Patents by Inventor Wu-Che Wen

Wu-Che Wen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING AN RNA VIRUS INDUCED DISEASE
    Publication number: 20230190680
    Abstract: The present invention provides methods and compositions for treating or reducing the symptoms of or preventing an RNA virus induced disease in a subject by cyclohexenone compounds.
    Type: Application
    Filed: May 7, 2021
    Publication date: June 22, 2023
    Inventors: Sheng-Yung Liu, Ching-Tien Su, Wu-Che Wen, Pei-Ni Chen
  • METHOD FOR THE TREATMENT OF FATTY LIVER DISEASE
    Publication number: 20210177775
    Abstract: The invention provides a method of treating, inhibiting and/or preventing fatty liver disease in a patient in need thereof, comprising administering an effective amount of a cyclohexenone compound of the following formula (I) to said patient,
    Type: Application
    Filed: February 20, 2021
    Publication date: June 17, 2021
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Method for the treatment of fatty liver disease
    Patent number: 10959963
    Abstract: The invention provides a method of treating, inhibiting and/or preventing fatty liver disease in a patient in need thereof, comprising administering an effective amount of a cyclohexenone compound of the following formula (I) to said patient,
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: March 30, 2021
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Methods and compositions for treating arteriosclerotic vascular diseases
    Patent number: 10905656
    Abstract: The present invention provides methods and compositions for treating arteriosclerotic vascular diseases by cyclohexenone compounds. In some embodiments, the compound in the methods inhibits PDGF-stimulated smooth muscle cell proliferation or migration. In some embodiments, the atherosclerosis is associated with coronary artery disease, aneurysm, arteriosclerosis, myocardial infarction, embolism, stroke, thrombosis, angina, vascular plaque inflammation, vascular plaque rupture, Kawasaki disease, calcification or inflammation. In some embodiments, the compound lowers low-density lipoprotein (LDL) cholesterol in the subject. In some embodiments, the compound maintains a normal low-density lipoprotein (LDL) cholesterol level in the subject.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: February 2, 2021
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • METHOD FOR THE TREATMENT OF FATTY LIVER DISEASE
    Publication number: 20200093757
    Abstract: The invention provides a method of treating, inhibiting and/or preventing fatty liver disease in a patient in need thereof, comprising administering an effective amount of a cyclohexenone compound of the following formula (I) to said patient,
    Type: Application
    Filed: November 29, 2019
    Publication date: March 26, 2020
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Methods and compositions for treating neurodegenerative diseases
    Patent number: 9861592
    Abstract: The present invention provides methods and compositions for treating neurodegenerative diseases by cyclohexenone compounds.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: January 9, 2018
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • METHOD FOR THE TREATMENT OF FATTY LIVER DISEASE
    Publication number: 20170304224
    Abstract: The invention provides a method of treating, inhibiting and/or preventing fatty liver disease in a patient in need thereof, comprising administering an effective amount of a cyclohexenone compound of the following formula (I) to said patient,
    Type: Application
    Filed: June 26, 2017
    Publication date: October 26, 2017
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Cyclohexenone Compositions and Process for Making Thereof
    Publication number: 20160251308
    Abstract: Provided herein are processes of preparing cyclohexenone compounds useful for cancer treatments and/or diseases.
    Type: Application
    Filed: May 9, 2016
    Publication date: September 1, 2016
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen, Hsiu-Yi Cheng
  • Methods and compositions for treating leukemia
    Patent number: 9403747
    Abstract: The present invention provides methods and compositions for treating leukemia by cyclohexenone compounds.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: August 2, 2016
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Cyclohexenone compositions and process for making thereof
    Patent number: 9365481
    Abstract: Provided herein are processes of preparing cyclohexenone compounds useful for cancer treatments and/or diseases.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: June 14, 2016
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen, Hsiu-Yi Cheng
  • Compositions for Improving the Development of Arteriosclerotic Vascular Diseases
    Publication number: 20150328272
    Abstract: The present invention provides methods and compositions for treating arteriosclerotic vascular diseases by pharmaceutical compositions comprising a component of at least one species from the genus Sargassum; a component of at least one species from the genus Lonicera; and a component of at least one species from the genus Cimicifuga.
    Type: Application
    Filed: June 17, 2013
    Publication date: November 19, 2015
    Inventors: Sheng-Yung LIU, Wu-Che WEN
  • METHODS AND COMPOSITIONS FOR TREATING ARTERIOSCLEROTIC VASCULAR DISEASES
    Publication number: 20150080477
    Abstract: The present invention provides methods and compositions for treating arteriosclerotic vascular diseases by cyclohexenone compounds. In some embodiments, the compound in the methods inhibits PDGF-stimulated smooth muscle cell proliferation or migration. In some embodiments, the atherosclerosis is associated with coronary artery disease, aneurysm, arteriosclerosis, myocardial infarction, embolism, stroke, thrombosis, angina, vascular plaque inflammation, vascular plaque rupture, Kawasaki disease, calcification or inflammation. In some embodiments, the compound lowers low-density lipoprotein (LDL) cholesterol in the subject. In some embodiments, the compound maintains a normal low-density lipoprotein (LDL) cholesterol level in the subject.
    Type: Application
    Filed: March 26, 2013
    Publication date: March 19, 2015
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Methods and Compositions for Treating Leukemia
    Publication number: 20150025135
    Abstract: The present invention provides methods and compositions for treating leukemia by cyclohexenone compounds.
    Type: Application
    Filed: February 20, 2014
    Publication date: January 22, 2015
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Cyclohexenone Compositions and Process for Making Thereof
    Publication number: 20150018567
    Abstract: Provided herein are processes of preparing cyclohexenone compounds useful for cancer treatments and/or diseases.
    Type: Application
    Filed: February 20, 2014
    Publication date: January 15, 2015
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen, Hsiu-Yi Cheng
  • THERAPEUTIC METHODS AND COMPOSITIONS UTILIZING CYCLOHEXENONE COMPOUNDS
    Publication number: 20150018296
    Abstract: The present invention is directed to therapeutic methods and compositions involving cyclohexenone compounds where said compounds inhibit farnesyltransferase or Ras. The therapeutic methods (e.g. for treating cancers) comprise contacting a tumor with a cyclohexenone compound and an anticancer agent.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 15, 2015
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • METHOD FOR THE TREATMENT OF FATTY LIVER DISEASE
    Publication number: 20140274979
    Abstract: The invention provides a method of treating, inhibiting and/or preventing fatty liver disease in a patient in need thereof, comprising administering an effective amount of a cyclohexenone compound of the following formula (I) to said patient,
    Type: Application
    Filed: March 13, 2013
    Publication date: September 18, 2014
    Inventors: Sheng-Yung Liu, Wu-Che Wen, Chih-Ming Chen
  • Inhibition of the Survival of Bladder Cancer by Cyclohexenone Compounds from Antrodia Camphorata
    Publication number: 20140179800
    Abstract: The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of bladder cancer cells and be used as a pharmaceutical composition to inhibit the bladder tumor growth.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yun Liu, Wu-Che Wen, Mao-Tien Kuo
  • Inhibition of the Survival of Lymphoma by Cyclohexenone Compounds from Antrodia Camphorata
    Publication number: 20140179801
    Abstract: The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3 -dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6, 10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of lymphoma cells and be used as a pharmaceutical composition to inhibit the lymphoma tumor growth.
    Type: Application
    Filed: March 3, 2014
    Publication date: June 26, 2014
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yun Liu, Wu-Che Wen, Mao-Tien Kuo
  • METHODS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES
    Publication number: 20140142194
    Abstract: The present invention provides methods and compositions for treating neurodegenerative diseases by cyclohexenone compounds.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 22, 2014
    Applicant: Golden Biotechnology Corporation
    Inventors: Sheng-Yung LIU, Wu-Che WEN, Chih-Ming CHEN
  • Methods and compositions for treating cancer metastasis
    Patent number: 8648117
    Abstract: The present invention provides methods and compositions for treating cancer metastasis by cyclohexenone compounds.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: February 11, 2014
    Assignee: Golden Biotechnology Corporation
    Inventors: Sheng-Yung Liu, Wu-Che Wen