Patents by Inventor X. Wang

X. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180011010
    Abstract: Disclosed herein are embodiments of sensor devices comprising a sensing component able to determine the presence of, detect, and/or quantify detectable species in a variety of environments and applications. The sensing components disclosed herein can comprise MOF materials, plasmonic nanomaterials, redox-active molecules, a metal, or any combinations thereof. In some exemplary embodiments, optical properties of the plasmonic nanomaterials and/or the redox-active molecules combined with MOF materials can be monitored directly to detect analyte species through their impact on external conditions surrounding the material or as a result of charge transfer to and from the plasmonic nanomaterial and/or the redox-active molecule as a result of interactions with the MOF material.
    Type: Application
    Filed: September 7, 2017
    Publication date: January 11, 2018
    Inventors: Chih-hung Chang, Ki-Joong Kim, Alan X. Wang, Yujing Zhang, Xinyuan Chong, John P. Baltrus, Paul R. Ohodnicki
  • Patent number: 9863939
    Abstract: Methods for analyte detection with magnetic sensors are provided. Aspects of the methods include producing a magnetic sensor device having a magnetically labeled analyte from a sample, such as a serum sample, bound to a surface of a magnetic sensor thereof; and obtaining a signal, e.g., a real-time signal, from the magnetic sensor to determine whether the analyte is present in the sample. Also provided are devices, systems and kits that find use in practicing the methods of the invention. The methods, devices, systems and kits of the invention find use in a variety of different applications, including detection of biomarkers, such as disease markers.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: January 9, 2018
    Assignees: MagArray, Inc., The Board of Trustees of the Leland Stanford Junior University
    Inventors: Shan X. Wang, Sebastian J. Osterfeld, Heng Yu, Nader Pourmand, Robert L. White
  • Publication number: 20180002760
    Abstract: A method for identification of circulating tumor cells (CTCs) in a blood sample uses magnetic enrichment and a nanowell assay. The CTCs are magnetically labeled with cancer cell markers conjugated to magnetic nanoparticles and then separated by passing the blood sample through a magnetic sifter. The enriched CTCs are then loaded into a microfluidic single-cell molecular assay comprising an array of 25,600 or more nanowells, each containing at most a single one of the CTCs. Using multiple fluorescent gene markers, simultaneous multiple-color multiplexed gene expression of the CTCs is performed, preferably using RT-PCR. Images of fluorescence signals from individual nanowells are analyzed to identify CTCs.
    Type: Application
    Filed: April 20, 2016
    Publication date: January 4, 2018
    Inventors: Seung-min Park, Dawson Wong, Chin Chun Ooi, Sanjiv Sam Gambhir, Viswam S. Nair, Shan X. Wang
  • Publication number: 20180002531
    Abstract: The present invention is directed to dirt and anti-microbial resistant articles that include a substrate, a powder coating applied to the substrate, the powder coating may comprise a cross-linked polymeric binder. The powder coating may comprise a blend of metal borate and a sulfur-containing benzimidazole compound, wherein the metal borate and sulfur-containing benzimidazole compound are present in a weight ratio ranging from about 75:1 to about 10:1. The powder coating may comprise fluorosurfactant and a fluorosurfactant may be applied to the powder coating in an amount ranging from about 0.01 g/m2 to about 4 g/m2. The powder coating may be formed using a liquid-based fluorosurfactant.
    Type: Application
    Filed: June 29, 2017
    Publication date: January 4, 2018
    Inventors: Steven L. Masia, Michelle X. Wang, Kenneth G. Caldwell
  • Publication number: 20180001297
    Abstract: Described herein is a building panel comprising a substrate and an odor and VOC reducing coating applied to the substrate, the coating comprising a blend of a first component comprising ethylene urea; a second component comprising silica; and a rheology modifier.
    Type: Application
    Filed: September 18, 2017
    Publication date: January 4, 2018
    Inventors: Kenneth G. Caldwell, Steven L. Masia, Gourish Sirdeshpande, Michelle X. Wang
  • Patent number: 9856251
    Abstract: The present invention provides processes for the synthesis of substituted berbine compounds. Also provided are intermediates used in the synthesis of substituted berbine compounds.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: January 2, 2018
    Assignee: Mallinckrodt LLC
    Inventors: Peter X. Wang, Frank W. Moser, Gary L. Cantrell, Christopher W. Grote
  • Publication number: 20170345589
    Abstract: A key mechanism is disclosed. The key mechanism comprises a keycap, a dome support structure positioned relative to the keycap and defining an opening, an actuation mechanism coupled to the keycap, and a collapsible dome positioned in the opening of the dome support structure. The actuation mechanism is configured to movably support the keycap relative to the dome support structure. The dome comprises an upstop member configured to limit upward travel of the collapsible dome.
    Type: Application
    Filed: May 24, 2016
    Publication date: November 30, 2017
    Inventors: Chia-Chi Wu, Zheng Gao, Ming Gavin Gao, Paul X. Wang, Alex J. Lehmann, Richard Xu, Kenneth M. Silz, Chia-Wei Lee
  • Patent number: 9831954
    Abstract: Techniques and solutions are provides for increasing data bandwidth to wireless devices in a wireless network. Data bandwidth to a wireless device can be increased by using an array of wireless transmitters of one type, arranged to cover one or more areas of an enclosed space, in combination with one or more wireless transmitters of another type, to simultaneously transmit data to the wireless device over different wireless communication channels.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: November 28, 2017
    Assignee: Oregon State University
    Inventors: Thinh P. Nguyen, Alan X. Wang
  • Publication number: 20170314260
    Abstract: Described herein is an stain and sag resistant acoustic ceiling panel comprising a porous body formed from mineral and cellulosic fibers having an upper surface opposite a lower surface and at least one side surface extending between the upper surface and the lower surface; a first layer applied to the upper surface, the first layer comprising a hygroscopic component and a hydrophobic component; and a second layer applied to the lower surface, the second layer comprising a hydrophobic component.
    Type: Application
    Filed: July 11, 2017
    Publication date: November 2, 2017
    Inventors: MICHELLE X. WANG, JOANNE LEFEVER, LIDA LU
  • Patent number: 9773612
    Abstract: A method of fabricating in-plane or out-of-plane thin-film multi-axial magnetic anisotropy devices is provided that includes either depositing a magnetic material with perpendicular or partially perpendicular anisotropy patterned into a multi-directional, curved, or closed path or depositing a thin-film of magnetic material on a piezoelectric material, where the magnetic material is arranged in a pattern, depositing excitation electrodes on the piezoelectric material, where the excitation electrodes are arranged in a pattern, biasing the piezoelectric material, by applying a voltage across the excitation electrodes, where an electric field through the piezoelectric material is generated by the applied voltage across the excitation electrodes, where the piezoelectric material is biased by the electric field to provide stress to the magnetic material, where the stress rotates a magnetization of the magnetic material, and patterning the magnetic material into a multi-directional, curved, or closed path.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: September 26, 2017
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Amal El-Ghazaly, Shan X. Wang
  • Patent number: 9764307
    Abstract: Described herein is a building panel comprising a substrate and an odor and VOC reducing coating applied to the substrate, the coating comprising a blend of a first component comprising ethylene urea; a second component comprising silica; and a rheology modifier.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: September 19, 2017
    Assignee: AWI Licensing LLC
    Inventors: Kenneth G. Caldwell, Steven L. Masia, Gourish Sirdeshpande, Michelle X. Wang
  • Patent number: 9702142
    Abstract: Described herein is an stain and sag resistant acoustic ceiling panel comprising a porous body formed from mineral and cellulosic fibers having an upper surface opposite a lower surface and at least one side surface extending between the upper surface and the lower surface; a first layer applied to the upper surface, the first layer comprising a hygroscopic component and a hydrophobic component; and a second layer applied to the lower surface, the second layer comprising a hydrophobic component.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: July 11, 2017
    Assignee: AWI Licensing LLC
    Inventors: Michelle X Wang, Joanne Lefever, Lida Lu
  • Publication number: 20170165636
    Abstract: Described herein is a building panel comprising a substrate and an odor and VOC reducing coating applied to the substrate, the coating comprising a blend of a first component comprising ethylene urea; a second component comprising silica; and a rheology modifier.
    Type: Application
    Filed: December 15, 2015
    Publication date: June 15, 2017
    Inventors: KENNETH G. CALDWELL, STEVEN L. MASIA, GOURISH SIRDESHPANDE, MICHELLE X. WANG
  • Patent number: 9656955
    Abstract: The present invention relates to pyrrolidine derivatives of the formula (I), or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such pyrrolidine derivatives, and the use of such pyrrolidine derivatives for therapeutic purposes. The pyrrolidine derivatives are GlyT1 inhibitors.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: May 23, 2017
    Assignees: AbbVie Inc., AbbVie Deutschland GmbH & Co. KG
    Inventors: Wilhelm Amberg, Frauke Pohlki, Udo Lange, Ying X. Wang, Hongyu H. Zhao, Huan-Qiu Li, Jason T. Brewer, Irini Zanze, Justin Dietrich, Anil Vasudevan, Stevan W. Djuric, Yanbin Lao, Charles W. Hutchins
  • Patent number: 9650334
    Abstract: The present invention relates to pyrrolidine derivatives of the formula (I), or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such pyrrolidine derivatives, and the use of such pyrrolidine derivatives for therapeutic purposes. The pyrrolidine derivatives are GlyT1 inhibitors.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: May 16, 2017
    Assignees: AbbVie Inc., AbbVie Deutschland GmbH & Co. KG
    Inventors: Wilhelm Amberg, Frauke Pohlki, Udo Lange, Ying X. Wang, Hongyu H. Zhao, Huan-Qiu Li, Jason T. Brewer, Irini Zanze, Justin Dietrich, Anil Vasudevan, Stevan W. Djuric, Yanbin Lao, Charles W. Hutchins
  • Publication number: 20170121982
    Abstract: The present invention is directed to a building panel having a laminate structure, the laminate structure including a topcoat layer comprising a first intumescent composition, a cellulosic veneer layer, an adhesive layer formed from an adhesive composition comprising a second intumescent composition, and a metallic substrate layer and wherein the cellulosic veneer layer is at least partially bonded to the metallic substrate by the adhesive layer. The resulting building panel exhibits superior flame retardancy resulting in a Class A fire rating, according to ASTM E-84.
    Type: Application
    Filed: October 26, 2016
    Publication date: May 4, 2017
    Inventors: Marsha S. Bischel, Kenneth P. Kehrer, Lida Lu, Michelle X. Wang
  • Patent number: 9637505
    Abstract: 4-Amino-6-(heterocyclic)picolinic acids and their derivatives; 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their derivatives; and methods of using the same as herbicides.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 2, 2017
    Assignee: Dow AgroSciences LLC
    Inventors: Joseph D. Eckelbarger, Jeffrey B. Epp, Stephen Craig Fields, Lindsey G. Fischer, Natalie C. Giampietro, Katherine A. Guenthenspberger, Christian T. Lowe, Jeff Petkus, Joshua Roth, Norbert M. Satchivi, Paul R. Schmitzer, Thomas L. Siddall, Nick X. Wang
  • Publication number: 20170097337
    Abstract: Small molecule analytes (less than 1000 Daltons) in a fluid sample are detected using a competitive assay in a magnetic biosensor. The fluid sample is added to a biosensor detection chamber together with detection probes and magnetic tags which bind to the detection probes. The magnetic biosensor is functionalized with a capture probe that shares an epitope with the analytes, and the detection probe is capable of binding the epitope shared by the analytes and the capture probe, so that the presence of the analyte prevents detection probes (and magnetic tags) from binding to the biosensor. By measuring the binding of the magnetic tags to the magnetic biosensor, an amount of analytes in the solution is determined.
    Type: Application
    Filed: September 30, 2016
    Publication date: April 6, 2017
    Inventors: Tyler O'Brien Shultz, Jung-Rok Lee, Shan X. Wang
  • Patent number: 9611282
    Abstract: 4-Amino-6-(heterocyclic)picolinic acids and their derivatives; 6-amino-2-(heterocyclic)pyrimidine-4-carboxylates and their derivatives; and methods of using the same as herbicides.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: April 4, 2017
    Assignee: Dow AgroSciences LLC
    Inventors: Joseph D. Eckelbarger, Jeffrey B. Epp, Stephen Craig Fields, Lindsey G. Fischer, Natalie C. Giampietro, Katherine A. Guenthenspberger, Christian T. Lowe, Jeff Petkus, Joshua Roth, Norbert M. Satchivi, Paul R. Schmitzer, Thomas L. Siddall, Nick X. Wang
  • Publication number: 20170082614
    Abstract: Disclosed herein are organometallic complexes and methods of using the same in detecting double stranded DNA or RNA, selectively over single stranded DNA or RNA.
    Type: Application
    Filed: May 22, 2015
    Publication date: March 23, 2017
    Inventors: Chad A. Mirkin, Chad M. Shade, Robert D. Kennedy, Jessica Lynn Rouge, Soyoung E. Seo, Mary X. Wang