Abstract: One or more computing devices, systems, and/or methods for identifying anomalous behavior of users are provided. In an example, users of a telecommunication service provider may be segmented into a plurality of user segments based upon telecommunication service metrics associated with the users. A machine learning model may be trained using telecommunication service information associated with users of the first user segment to generate a trained machine learning model. Using the trained machine learning model, a forecast of telecommunication service usage associated with a first user segment of the plurality of user segments. A telecommunication service usage metric, associated with a user belonging to the first user segment, may be compared with a range indicated by the forecast. The user may be flagged as having anomalous behavior based upon a determination that one or more telecommunication usage metrics, associated with the user, are outside one or more ranges indicated by the forecast.

Abstract: Some demonstrative embodiments include devices, systems and/or methods of simultaneously communicating with a group of wireless communication devices. For example, a device may include a wireless communication unit to communicate with at least one group of a plurality of wireless communication devices over a wireless communication medium, wherein the wireless communication unit is to reserve the wireless communication medium for a time period, during which the wireless communication unit is to simultaneously transmit two or more different wireless communication transmissions to two or more wireless communication devices of the group, respectively. Other embodiments are described and claimed.

Abstract: Disclosed herein are antibodies useful that bind to connexin 43 hemichannels to inhibit or block channel opening. Also disclosed herein are methods for detecting or treating osteoarthritis, rheumatoid arthritis, and tendon disorders and injuries with antibodies that inhibit or block Cx43 hemichannel opening.

Abstract: Low-profile computer supports include features to reduce the thickness and improve the portability or storage capability of a computer system while it is disassembled, packaged, shipped, or moved. Some computer systems have a computing device and a dock device that can be stored and moved separately or that can store or support accessories associated with the computer system. Some computer systems have a movable stand configured to transition between a collapsed state and a deployed or standing state. Some stands include handles or grips for moving the computer systems while collapsed. Other computer systems include handles or grips to provide areas to more easily carry the computer systems. The handles or grips can have features such as a flexible material to hide or mask their appearance on the computer system.

Abstract: The present application relates to pharmaceutical formulations and dosage forms of an AXL/MER inhibitor, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, including methods of preparation thereof, which are useful in the treatment of AXL/MER mediated diseases such as cancer.

Abstract: An airfoil includes an airfoil wall that has a wishbone-shaped fiber layup structure. The structure includes two arms that merge into a single leg. The single leg includes fiber tows from each of the arms that are interwoven. The single leg forms at least a portion of the trailing edge of the airfoil wall. Each of the arms includes a first section that is distal from the single leg and a second section that is proximal to the single leg. The first section defines a first thickness, the second section defines a second thickness that is greater than the first thickness, and the single leg defines a third thickness that is greater than the second thickness.

Abstract: A technology is described for redundant network communication in a robot. An example of the technology can include a main robotic controller and a robotic component including a local controller and a controlled component that is operable based on a data signal comprising control instructions executed by the local controller. A command can be sent between the main robotic controller and the local controller. The command can be encoded in a first data signal and a second data signal. The first data signal can be sent over a first network channel, and the second data signal can be sent over a second network channel. The first data signal and the second data signal can be configured to be redundant data signals for the local controller sent respectively over the first network channel and the second network channel.

Abstract: A head-mounted device may include a main housing portion and displays in the main housing portion that provide images to eye boxes. A light seal may be coupled to the main housing portion and may at least partially surround the eye boxes. The head-mounted device may include sweat mitigation structures such as moisture-guiding channels in the light seal to guide sweat and other moisture away from the eye boxes. The moisture-guiding channels may be formed from grooves or moisture-wicking fabric. Control circuitry may adjust a fan based on humidity, temperature, or fog detected by a sensor. The light seal may include a directional pattern of grooves through which moisture is guided away from the eye boxes. A moisture barrier layer may be interposed between an inner foam layer and an outer light-blocking fabric to prevent sweat from penetrating into the foam.

Abstract: An electronic device may include a glass housing member that includes an upper portion defining a display area, a lower portion defining an input area, and a transition portion joining the upper portion and the lower portion and defining a continuous, curved surface between the upper portion and the lower portion. The electronic device may include a display coupled to the glass housing member and configured to provide a visual output at the display area. The electronic device may include an input device coupled to the glass housing member and configured to detect inputs at the input area. The electronic device may include a support structure coupled to the glass housing member and configured to support the computing device.

Abstract: Devices, systems, methods, and computer program products for performing a medical procedure are disclosed herein. In some embodiments, a system for performing a medical procedure in an anatomic region includes a medical instrument configured to be inserted within the anatomic region, the medical instrument including an image capture device. The system can also include a positional sensor associated with the medical instrument. The system can be configured to receive a model of the anatomic region. The system can obtain image data from the image capture device and a set of coordinate points from the positional sensor. The system can generate a registration between the model and the anatomic region based on the image data and the coordinate points.

Abstract: A system may include an electronic device such as a head-mounted device and a handheld controller for controlling the electronic device. The handheld controller may have a housing with an elongated shaft extending between first and second tip portions. The handheld controller may have power receiving circuitry configured to receive power from a power source. The power source may be incorporated into an electronic device such as a wireless charging dock or stick, a battery case, or a head-mounted device. The power source may supply power through terminals that form ohmic contacts with mating terminals in the finger device or may transmit power wirelessly using capacitive coupling or inductive charging arrangements. Magnets may be used to hold and align the elongated shaft of the handheld controller on the power source.

Abstract: A rotary shaft assembly includes a rotary shaft having a first end portion, a second end portion opposite the first end portion, a longitudinal axis extending centrally through the first and second end portions, and a shaft body that defines a bore between the first and second end portions. An anti-flailing mechanism is positioned within the bore of the shaft body. The anti-flailing mechanism is coupled to rotary shaft and extends at least partially between the first and second end portions to contain the rotary shaft about the longitudinal axis when the rotary shaft fails.

Abstract: A method of identifying methylated cell-free DNA (cfDNA) biomarkers is provided, referred to as layered analysis of methylated biomarkers (LAMB). In particular, the LAMB methodology can be used to analyze data from patients to discover methylated cfDNA biomarkers associated with cancer. LAMB was used to identify tumor suppressor candidates using meta-analysis of cancer tissue methylation studies, followed by screening for tumor-specific promoter CpGs in these tumor suppressors and analysis of microarray data for cancerous tissues, non-cancerous tissues adjacent to tumors, and healthy blood samples. Biomarker panels for diagnosis of liver, colorectal, prostate, and lung cancer as well as biomarkers for predicting tumor response to therapy are provided based on this LAMB methodology. The biomarkers identified by LAMB can be used alone or in combination with one or more additional biomarkers or relevant clinical parameters in prognosis, diagnosis, therapy selection, or monitoring treatment of cancer.

Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

Abstract: A finger-mounted device may include finger-mounted units. The finger-mounted units may each have a body that serves as a support structure for components such as force sensors, accelerometers, and other sensors and for haptic output devices. The body may have sidewall portions coupled by a portion that rests adjacent to a user's fingernail. The body may be formed from deformable material such as metal or may be formed from adjustable structures such as sliding body portions that are coupled to each other using magnetic attraction, springs, or other structures. The body of each finger-mounted unit may have a U-shaped cross-sectional profile that leaves the finger pad of each finger exposed when the body is coupled to a fingertip of a user's finger. Control circuitry may gather finger press input, lateral finger movement input, and finger tap input using the sensors and may provide haptic output using the haptic output device.

Abstract: Antibodies that bind to connexin 43 hemichannels and inhibit, or activate, channel opening are provided. In certain aspects, methods for detecting or treating cancers with antibodies that activate Cx43 channel opening are also provided. Likewise, methods for treating inflammatory diseases (e.g., osteoarthritis) and neurological injuries (e.g., spinal cord injury) with antibodies that inhibit Cx43 channel opening are provided.

Abstract: Methods for identifying compounds that positively regulate connexin 43 hemichannels.

Abstract: A head-mountable device can have multiple cameras, which may be used to generate graphical content, provide a video passthrough of the environment, and/or sense objects, people, or events in the environment. The cameras of the head-mountable device can capture views that are output to a display. Other sensors and/or detectors can detect the presence or motion of objects and/or events in an environment of the user and provide outputs that call the user's attention to such objects and/or events. The outputs can include notifications, selectable features of a visual display output, and/or a view that includes the objects and/or events. The cameras can be integrated in a way that provides a low profile, such as by incorporation with other features of the head-mountable device.

Abstract: A robotic joint system is provided that facilitates efficient movement of a ground-contacting robotic system, such as during a gait cycle. The robotic joint system can comprise a first support member, a second support member, and a joint assembly rotatably coupling the first support member to the second support member about an axis of rotation. The joint assembly can comprise a passive actuation system coupled between the first and second support members. The passive actuation system can comprise a passive actuator operable to store energy and to release energy to apply a torque to the joint assembly and the first and second support members, and a length adapter coupled to the passive actuator operable to selectively direct the output of the stored energy of the passive actuator.

Abstract: A head-mountable device can operate in concert with one or more optical assemblies thereof to provide multiple users with shared experiences and content enjoyment. Such operations can be facilitated by a connection between the head-mountable device and one or both of its optical assemblies to allow different users to receive content. Such a connection can be made possible by a communication link that directly and/or physically connects the head-mountable device and one or both of its optical assemblies when the one or both of the optical assemblies is removed from the head-mountable device for operation by a separate user. The ability to provide multiple outputs on separate components allows separate users to participate in a shared experience.