Abstract: Oxindole compounds useful for the treatment of CCR(9) mediated conditions or diseases are provided.

Abstract: The present disclosure relates to a quantum key distribution (QKD) method based on a tree QKD network. The method includes: judging a position of a parent node of the source node S0 and a position of a parent node of the destination node Sd; if the parent node is a trusted relay node, directly transferring an initial shared key of the source node S0 and the parent node to the destination node Sd according to an exclusive OR (XOR) relay scheme, and ending the process; and if the parent node is an untrusted relay node, emitting, by the source node S0 and the destination node Sd, photons to a measuring-device-independent quantum key distribution (MDI-QKD) receiver of the parent node through a QKD emitter, generating a shared key by an MDI-QKD method, then transmitting the shared key according to the XOR relay scheme, and ending the process.

Abstract: A system and a method are disclosed for a tool that generates a provider score corresponding to a predicted performance of a provider based on data of claims involving the provider. For a given claim, the tool provides the data as input into a supervised machine learning model and receives as output from the supervised machine learning model a predicted performance of the claim. The tool also inputs the data of the claim into an unsupervised machine learning model that is selected based on a stage of claim processing that the claim belongs to and receives as output from the unsupervised machine learning model an identification of a cluster of candidate claims to which the claim belongs. The tool combines the outputs of the supervised machine learning model and the unsupervised machine learning model to generate the provider score.

Abstract: The present disclosure provides a method and system for determining a helicopter rotor airfoil.

Abstract: Disclosed is a neural network-based inference method and apparatus. The neural network-based inference method includes compressing a matrix comprising processing elements corresponding to an operation of a neural network, balancing workloads related to the operation by reordering the compressed matrix based on the workloads, and performing inference based on the reordered matrix.

Abstract: An improved gel composite electrolyte membrane and a method of its manufacture are provided. The method includes mixing polymer precursors, a lithium salt, and a ceramic filler in a vessel to form a mixture. The mixture is cast on a preheated substrate and cured to form a crosslinked composite electrolyte membrane. The composite electrolyte membrane is plasticized by immersing the composite electrolyte in a plasticizer to obtain a gel composite electrolyte membrane. The addition of a plasticizer and a ceramic filler synergistically and simultaneously act to improve the Li+ transference number and Li+ conductivity of the resulting composite electrolyte, exhibiting high ionic conductivity and mechanical stability as well improved cycling performance. The gel composite electrolyte membrane is particularly suitable for, but not limited to, lithium metal batteries.

Abstract: A collision avoidance assist apparatus includes: a front-and-lateral target information acquisition device configured to acquire front-and-lateral target information; a vehicle information acquisition device configured to acquire vehicle information including a vehicle speed and at least one of a yaw rate or a steering input value; and a control unit configured to execute collision avoidance assist control when a target satisfies a collision condition that is satisfied when the target is determined to have collision possibility. The control unit selects targets that satisfy a predetermined selection condition from targets in the front-and-lateral target information, determines whether the collision condition is satisfied for each selected target, determines, when this determination is to be made, whether an own vehicle is turning based on the vehicle information, and changes the selection condition between a case in which the own vehicle is not turning and a case in which the own vehicle is turning.

Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y?, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.

Abstract: In an example embodiment, submitted confidential data of a certain cohort (e.g., title, region, organization) is split into two components covering different portions of the cohort attributes (e.g., a first portion for (title, region)-wise confidential data values and a second portion of organization-wise compensation adjustments). These two portions are then analyzed separately and the inferences from both models are integrated together to obtain predictions for compensation values for the cohort as a whole.

Abstract: The present disclosure provides compositions and methods to make and use ribonucleic acid sequences encoding viral proteins (e.g., Rep and Cap proteins) derived from adeno-associated viruses. The RNA sequences can be delivered into a host cell for viral packaging.

Abstract: The present disclosure provides a one-time programmable capacitive fuse bit, including an upper plate, the upper plate includes a plurality of fuses arranged side by side and spaced by an internal from each other, middle portions of two adjacent fuses are connected to each other; a connecting portion connected to the fuse is disposed above two ends and the middle portion of each of the plurality of fuses; the fuse bit further includes a lower plate corresponding to the two ends and the middle portion of the fuse, the lower plate is disposed below the fuse; the lower plate corresponding to the middle portion of the fuse is opposite to the connecting portion corresponding to the middle portion of the fuse; a hollow portion is disposed between the lower plate corresponding to the middle portion of the fuse and the lower plate corresponding to both ends of the fuse.

Abstract: An array substrate, a display panel, a display device, and a manufacturing method for an array substrate are provided. The array substrate includes a pixel unit group which includes a first pixel and a second pixel; the first pixel includes a first pixel electrode, a first switching element, and a first connection portion extending and protruding from the first pixel electrode; the second pixel includes a second pixel electrode, a second switching element, and a second connection portion extending and protruding from the second pixel electrode; the first pixel electrode and the first switching element are electrically connected to each other via the first connection portion; the second pixel electrode and the second switching element are electrically connected to each other via the second connection portion; and an extension length of the first connection portion is not equal to an extension length of the second connection portion.

Abstract: Presented herein are systems and methods for an end-to-end solution for object removal from a video using adaptive learning. In one or more embodiments, using a pre-trained image inpainting models, in-scene training data may be generated using optical-flow guided sampling. In one or more embodiments, the sampled patches are used to generate a training dataset, which is used to further train the image inpainting model until reaching a stop condition. The adaptively trained inpainting model may be used to generate a modified video in which the desired object or objects have been removed and the corresponding removed portion(s) have been filled (or inpainted) to preserve the integrity of the image.

Abstract: A system for operating a vehicle includes a first temperature sensor located at a first location and configured to measure a first temperature; a second temperature sensor located at a second location configured to measure a second temperature; and one or more processors. The one or more processors are individually or collectively configured to receive information regarding the first temperature and/or the second temperature; process the information; and impose a restriction affecting operation of the vehicle based on the processed information.

Abstract: An apparatus includes an optical source of an optical wavelength carrier, an optical modulator to receive the optical wavelength carrier, and an optical data receiver. The optical data modulator is configured to produce, from the optical wavelength carrier, an optical signal to carry separate data on different first and second components thereof in individual modulation periods during data transmission and to carry a training sequence on one of the components during time slots for calibration. The first component is relatively phase offset from the second component in the optical signal. The optical data modulator alternates the one of the components between the first and second components over the time slots for calibration. The optical receiver is connected to receive a portion of the optical signal and to temporally interleave a measurement of a characteristic of the first component and a measurement of a characteristic of the second component over the time slots for calibration.

Abstract: The subject invention pertains to lysins fused to a CeA peptide fragment, particularly at the C-terminus of the lysin. The subject invention also pertains to recombinant DNA encoding said lysins, vectors encoding said recombinant DNA, host cells comprising said vectors, and compositions comprising said lysins. The invention further pertains to a method of treating a bacterial infection, particularly a Gram-negative bacterial infection.

Abstract: A wearable electronic device such as an earbud, wristwatch, or other device may be provided with a skin sensor. The skin sensor may use optical measurements to detect the presence of skin adjacent to the electronic device. The sensor may have first and second light-emitting devices such as infrared devices that emit light at respective first and second infrared light wavelengths. Reflected light is monitored by a photodetector. Control circuitry can initiate or pause audio playback or take other actions in response to determining from the reflected light measurements that skin is present. The sensor may have a thin-film interference filter or other optical structure that overlaps the first and second light-emitting devices to narrow the angular spread of light emitted from the skin sensor. This reduces tilt sensitivity and helps enhance skin sensor accuracy.

Abstract: The present disclosure relates to an in-situ testing device including a measuring head, a drive mechanism, and a testing chamber. The testing chamber is provided with a first optical observation hole. The measuring head is provided with a second optical observation hole. The testing chamber is provided with an opening allowing the measuring head to pass. The testing chamber is further provided with a shielding door, and the drive mechanism is connected to the shielding door to drive the shielding door to move relative to the testing chamber, to open or cover the opening, thereby opening or closing the testing chamber.

Abstract: A method for exchange imaging of at least two targets in a sample includes (a) incubating a sample with at least two or more target-recognizing antibodies, each bound to a corresponding monovalent tight antibody binder-docketing moiety (MTAB-DM) reagent capable of binding monovalently to the target-recognizing antibodies, (b) applying at least two imager moieties corresponding to the MTAB-DM, either in series, in batches, or in parallel, and (d) imaging the at least two imager moieties either in series, in batches, or in parallel.