Abstract: The invention relates to stable formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof and a PH20 variant or fragment thereof. The invention further provides methods for treating various cancers with formulations of the invention. In some embodiments of the methods of the invention, the formulations are administered to a subject by subcutaneous administration.

Abstract: The present disclosure relates to a photoinitiating composition suitable for UV-LED light irradiation comprising: a) a photoinitiating system suitable for LED light irradiation having a wavelength in the range of 340-420 nm; b) a dispersing medium; wherein the dispersing medium comprises an organic solvent which is miscible with water.

Abstract: A process for converting naphtha to light olefins comprises contacting a naphtha stream with a zeolitic catalyst to produce a light paraffin stream. The light paraffin may be separated into an ethane stream and a propane stream. The ethane in the ethane stream may be converted into ethylene, and the propane in the propane in the propane stream may be converted into propylene. The light paraffin stream may also be separated into a heavy stream which may be recycled back to the contacting step.

Abstract: A process for converting naphtha to light olefins comprises contacting a naphtha stream with a zeolitic catalyst to produce a light paraffin stream at conditions which dehydrogenate the naphtha to olefins, interconvert the olefins to lighter olefins and hydrogenate the lighter olefins to produce a light paraffin stream comprising ethane and propane. The catalyst may comprise a zeolite and a metal.

Abstract: Disclosed herein are methods of detecting viruses and methods of making a diagnosis of viral infection, by using RNA and DNA probes. According to some embodiments of the present disclosure, the method is useful in detecting and diagnosing SARS-CoV-2 infection. Accordingly, also disclosed herein are a kit for detecting SARS-CoV-2.

Abstract: The present application relates to a coating composition and wood article manufactured therefrom, the coating composition comprising: (A) a film-forming resin composition comprising a reactive donor capable of providing two or more nucleophilic carbanions, and a reactive acceptor comprising two or more carbon-carbon double bonds; (B) a catalyst for catalyzing the Michael addition crosslinking reaction between the reactive donor and the reactive acceptor, wherein the reactive donor has an aromatic epoxy backbone, and wherein the reactive donor has an epoxy equivalent weight in the range of from 400 to 1100 g/mol, preferably in the range of from 470 to 1000 g/mol, more preferably in the range of from 470 to 900 g/mol.

Abstract: The present invention provides an anti-ErbB2 antibody-drug conjugate, a composition comprising the conjugate, a method for preparing the conjugate, and use of the conjugate.

Abstract: An improved MFI zeolite having low aluminum occupation at intersection sites characterized by an ortho-xylene to para-xylene uptake ratio of 0.1 to about 0.55. Processes for converting hydrocarbon or oxygenate to a product comprising light olefins and/or aromatics using the improved MFI zeolite as catalyst are also disclosed. Para-xylene in the product may be greater than about 24% of the xylenes.

Abstract: Provided are a UV-curable non-isocyanate polyurea polymer and a UV-curable coating composition containing the same. The UV-curable non-isocyanate polyurea polymer has one or more ethylenically unsaturated functional groups and the ethylenically unsaturated functional groups are attached to nitrogen atoms present in a backbone urea segment via —C(=0)- linkage. The nonisocyanate polyurea polymer is prepared by: (i) providing an ethylenically unsaturated compound having one or more carboxylic acid functional groups; and (ii) reacting said ethylenically unsaturated compound having one or more carboxylic acid functional groups with a multi-carbodiimide polymer to form the non-isocyanate polyurea polymer.

Abstract: The present disclosure is directed to an aqueous dispersion of polymeric particles having core-shell structure, the preparation thereof and the coating formed therefrom. In the polymeric particles, at least one of the polymeric core and the polymeric shell is formed from a monomers mixture comprising isobornyl (meth)acrylate and wherein the isobornyl (meth)acrylate is present in the monomers mixture in an amount of 1 wt % to 40 wt %, relative to the weight of the corresponding monomers mixture for the polymeric core or the polymeric shell.

Abstract: The present description provides a Michael Addition curable composition, comprising A) at least one reactive donor capable of providing two or more nucleophilic carbanions; B) at least one reactive acceptor comprising two or more carbon-carbon double bonds; and C) at least one catalyst for catalyzing the Michael Addition crosslinking reaction between the at least one reactive donor and the at least one reactive acceptor. The present description further provides a coating composition containing the composition and a coated article made therefrom.

Abstract: The present invention discloses a ketone-aldehyde modified resin and the preparation process thereof. The ketone-aldehyde modified resin comprises a ketone-aldehyde modified unsaturated polyester, a ketone-aldehyde modified unsaturated alkyd or the combination thereof, and wherein the said resin has ketone-aldehyde moieties. The process of the said resin comprises the steps of: reacting unsaturated polyester-forming and/or unsaturated alkyd resin-forming monomer components with a ketone-aldehyde resin. The present invention also discloses a coating composition comprising the said resin as well as a coated article. The ketone-aldehyde modified resin and the coating composition achieve significantly improved fast drying effect, while other properties are not observably impaired or even improved.

Abstract: The present disclosure provides a contact structure and an electronic device having the same. The contact structure includes a substrate, a copper layer, an organic composite protective layer, and a silver nanowire layer. The copper layer is disposed on the substrate. The nanowire-distribution-promotion layer is disposed between the copper layer and the silver nanowire layer.

Abstract: The present disclosure provides a contact structure and an electronic device having the same. The contact structure includes: a substrate; a copper layer disposed on the substrate; an adhesion promotion layer disposed on the copper layer, wherein the adhesion promotion layer forms a monomolecular adsorption layer on the surface of the copper layer; and a silver nanowire layer disposed on the adhesion promotion layer, and the adhesive force between the copper layer and the silver nanowire layer is 3B or more. In the present disclosure, by disposing the adhesion promotion layer on the copper layer, in the stacked structure of the copper layer and the silver nanowire layer, the adhesive force between the copper layer and the silver nanowire layer is increased, so as to prevent a peeling phenomenon of the copper layer occurring in the subsequent yellow-light process.

Abstract: A system, method, or device for imaging the anterior segment of an eye includes a contactless adapter/lens that may be attached to an existing ophthalmic imaging system to redirect the imaging system's light beam to traverse the pupil of the eye at a steep angle. In particular, the steep angle is determined to permit the ophthalmic imaging system to image zonules under the iris, and which would typically be blocked by the iris and not accessible for imaging.

Abstract: A de-hydrogenation catalyst and its use in dehydrogenation of hydrocarbons. The catalyst has low cracking activity and comprises gallium or gallium and platinum on an essentially non-acidic and amorphous alumina-phosphate or silica-alumina-phosphate support with an empirical chemical composition of [Al2O3][SiO2]Y[P2O5]Z, wherein Y is between 0 and 0.2 and Z is between 0.01 and 1.1, with a BET surface area above 50 m2/g, as measured by N2 adsorption experiment.

Abstract: The present invention is a water dispersible copolymer for scavenging formaldehyde, the copolymer being based on acrylic copolymer comprising one or more acetoacetyl functional groups and one or more hydrophilic groups chemically bonded to its molecular backbone, wherein the acrylic copolymer has a number average molecular weight of 2000-100,000 g/mol; and wherein the acrylic copolymer comprises between 10 wt % and 30 wt % of the acetoacetyl functional groups relative to the weight of the acrylic copolymer. The present invention also refers to an aqueous dispersion containing said water dispersible copolymer, as well as an article coated by a coating comprising the aqueous dispersion.

Abstract: The present disclosure provides an extrusion forming die for a cabin component. The extrusion forming die for a cabin component comprises an upper die assembly, a lower die assembly and a combined concave die. The upper die assembly comprises an extrusion punch (3), and the combined concave die comprises an M-shaped outer concave die (4) having a hollow cavity matched with the extrusion punch (3), and a W-shaped inner concave die (5) having a rotary cavity. The W-shaped inner concave die (5) is arranged in the rotary cavity of the M-shaped outer concave die (4) in a matched manner, and the rotary cavity and the hollow cavity are matched to form a rotary extrusion die cavity (18) with a W-shaped longitudinal section.

Abstract: The present disclosure provides a contact structure and an electronic device having the same. The contact structure includes a substrate, a copper layer, an organic composite protective layer, and a silver nanowire layer. The copper layer is disposed on the substrate. The nanowire-distribution-promotion layer is disposed between the copper layer and the silver nanowire layer.