Abstract: A spectrometer has a multi-input aperture for admitting an input wavefront and an array of multiple waveguide structures terminating at the multi-input aperture. The input wavefront is incident on each of the waveguide structures, which provide a dispersive function for the input wavefront. Interferometers are formed by elements of the waveguide structures. The interferometers have different optical path length differences (OPDs). The interferometers provide a wavelength responsive output for spatially extended light sources. The output of the interferometers is detected with a detector array. The spectrometer has an improved etendue, and in some embodiments very high resolution.

Abstract: A waveguide cores consisting of a subwavelength grating permits transmission of light without diffraction in a discontinuous manner, wherein the energy is provided by field hopping between subwavelength material segments of higher index. The use of alternating segments permits design of waveguides having desired effective index, mode confinement factor, birefringence, polarization mode or mode dispersions, polarization dependent loss, thermal sensitivity, or nonlinear optical coefficient. An optical system comprises a waveguide having such a core, clad on at least one side, extending between two ends, and wavelength-limiting optical components in optical communication with the ends.

Abstract: Embodiments include methods, apparatus, and systems for managing snapshots in storage systems. One method includes logically linking a plurality of snapshots to a logical disk in a storage network; and splitting the snapshots from the logical disk to form a snapshot tree that includes the snapshots split from the logical disk.

Abstract: A technique for high sensitivity evanescent field molecular sensing employs a detection scheme that simultaneously couples a polarized beam to a single mode of a waveguide, and couples the polarized beam out of the waveguide to specularly reflect the beam by the same grating. Strong interaction with the single (preferably TM) mode is provided by using a silicon on insulator (SOI) wafer having a waveguide thickness chosen between 10-400 nm so that the majority of the mode field strength spans the evanescent field. Well known, robust techniques for producing a grating on the waveguide are provided. Interrogation from a backside of the SOI wafer is taught.

Abstract: Methods and devices related to a sensor element for use in the detection and monitoring of molecular interactions. The sensor element uses a silicon-on-insulator wafer optically coupled to a silicon prism. The wafer has a thin silicon film top layer, a silicon substrate layer, and a buried silicon dioxide layer sandwiched between the silicon film and substrate layers. The wafer is coupled to the prism on the wafer's substrate side while the interactions to be monitored are placed on the wafer's silicon film side. An incident beam is directed at the prism and the incident angle is adjusted until the beam optically couples to the silicon film's optical waveguide mode. When this occurs, a decrease in the intensity of the reflected beam can be detected. The molecular interactions affect the phase velocity or wave vector of the propagating mode. Similarly, instead of measuring the incident angle at which optical coupling occurs, the phase of the reflected beam may be measured.

Abstract: Methods for enhancing detection by mass spectroscopy (MS) and/or chromatographic separability of carbonyl-containing compounds such as steroids are disclosed. Reaction of a carbonyl compound with a sulfonhydrazide compound provides a sulfonhydrazone with enhanced ionization efficiency during the electrospray ionization process. In a particularly disclosed embodiment, derivatization of catechol estrogens with p-toluenesulfonhydrazide enhances both detection by atmospheric pressure ionization-MS (API-MS), such as electron spray ionization-MS (ESI-MS) and separation by liquid chromatography (such as HPLC) under reverse phase conditions. In yet other embodiments, the sulfonhydrazone is further reacted with a sulfonyl halide under alkaline conditions to derivatize hydroxyl groups in the compound. Prior formation of the sulfonhydrazide derivative protects the carbonyl bond of the compound during subsequent alkaline reaction with the sulfonyl halide.

Abstract: A new and distinct cultivar of the muscadine grape plant, Vitis rotundifolia Michx., which has exceptionally good flavor, firm flesh texture with relatively thin skin, and a larger berry than the current grapes that are produced commercially. The vines of this cultivar are vigorous, productive and disease resistant.

Abstract: Various embodiments of the present invention are directed to an instant snapshot-tree-copy operation that, when directed to an existing snapshot tree, generates a data-structure framework for a copy of the existing snapshot tree that can be immediately accessed while a background-copy process copies data from the existing snapshot tree to the copy snapshot tree. The background-copy process copies data from the existing snapshot tree to the copy snapshot tree in top-down fashion, from the source logical device through each of the snapshot logical devices. While copying each logical device, the background-copy process sequentially copies data-storage units from a corresponding logical device of the existing snapshot tree to the copy-snapshot-tree logical device, making sure to adjust chains of dependencies within the copy snapshot tree to reflect modifications to the snapshot copy tree that occur independently from the background-copy process.

Abstract: Methods and devices relating to a sensor for use in detecting and monitoring molecular interactions. A silicon waveguide sensing element is provided along with a layer of silicon. A silicon oxide layer is also provided between the waveguide element and the layer of silicon. The sensing element is adjacent to an aqueous solution in which the molecular interactions are occurring. A light beam travelling in the silicon waveguide creates an evanescent optical field on the surface of the sensing element adjacent to the boundary between the sensing element and the aqueous medium. Molecular interactions occurring on this surface affect the intensity or the phase of the light beam travelling through the waveguide by changing the effective refractive index of the medium. By measuring the effect on the intensity, phase, or speed of the light beam, the molecular interactions can be detected and monitored in real time.

Abstract: Methods and devices relating to sensors and sensor blocks for use in detecting and monitoring molecular interactions. A silicon waveguide sensing element is provided along with a layer of silicon. A silicon oxide layer is also provided between the waveguide element and the layer of silicon. The sensing element is adjacent to an aqueous solution in which the molecular interactions are occurring. A light beam travelling in the silicon waveguide creates an evanescent optical field on the surface of the sensing element adjacent to the boundary between the sensing element and the aqueous medium. Molecular interactions occurring on this surface affect the intensity or the phase of the light beam travelling through the waveguide by changing the effective refractive index of the medium. By measuring the effect on the intensity, phase, or speed of the light beam, the molecular interactions can be detected and monitored in real time. Various configurations using this sensor technology is also disclosed.

Abstract: A spectrometer has a multi-input aperture for admitting an input wavefront and an array of multiple waveguide structures terminating at the multi-input aperture. The input wavefront is incident on each of the waveguide structures, which provide a dispersive function for the input wavefront. Interferometers are formed by elements of the waveguide structures. The interferometers have different optical path length differences (OPDs). The interferometers provide a wavelength responsive output for spatially extended light sources. The output of the interferometers is detected with a detector array. The spectrometer has an improved etendue, and in some embodiments very high resolution.

Abstract: An interface device for performing mode transformation in optical waveguides includes an optical waveguide core for propagating light of a particular wavelength or a plurality of wavelengths. The optical waveguide core terminates in a subwavelength grating configured to change the propagation mode of the light. The subwavelength grating has a pitch sufficiently less than the wavelength of the light to frustrate diffraction. The device can thus serve as an optical coupler between different propagating media, or as an anti-reflective or high reflectivity device.

Abstract: Mass-spectrometry based methods of analyzing estrogens and other steroids from biological tissue sections samples are disclosed herein. Methods of detecting a disease state or condition or elevated risk of a disease state or condition in a mammal from tissue sections are also disclosed.

Abstract: Various embodiments of the present invention are directed to an instant snapshot-tree-copy operation that, when directed to an existing snapshot tree, generates a data-structure framework for a copy of the existing snapshot tree that can be immediately accessed while a background-copy process copies data from the existing snapshot tree to the copy snapshot tree. The background-copy process copies data from the existing snapshot tree to the copy snapshot tree in top-down fashion, from the source logical device through each of the snapshot logical devices. While copying each logical device, the background-copy process sequentially copies data-storage units from a corresponding logical device of the existing snapshot tree to the copy-snapshot-tree logical device, making sure to adjust chains of dependencies within the copy snapshot tree to reflect modifications to the snapshot copy tree that occur independently from the background-copy process.

Abstract: Exemplary storage network architectures, data architectures, and methods for data restore operation are disclosed. In one embodiment, a storage device comprises a processor, a memory module communicatively connected to the processor, and logic instructions in the memory module which, when executed by the processor, configure the processor to receive a signal that identifies a source volume and a first target snapshot that represents a point in time copy of the source volume, update metadata to define an restore relationship between the first target snapshot and the source volume, execute a background copy process between the first target snapshot and the source volume, and manage input/output operations during the background copy process to permit input/output operations to the source volume during the background copy process.

Abstract: An interface device for performing mode transformation in optical waveguides includes an optical waveguide core for propagating light of a particular wavelength. The optical waveguide core terminates in a subwavelength grating configured to change the propagation mode of the light. The subwavelength grating has a pitch sufficiently less than the wavelength of the light to frustrate diffraction. The device can thus serve as an optical coupler between different propagating media, or as an anti-reflective or high reflectivity device.

Abstract: An interface device for performing mode transformation in optical waveguides includes an optical waveguide core for propagating light of a particular wavelength or a plurality of wavelengths. The optical waveguide core terminates in a subwavelength grating configured to change the propagation mode of the light. The subwavelength grating has a pitch sufficiently less than the wavelength of the light to frustrate diffraction. The device can thus serve as an optical coupler between different propagating media, or as an anti-reflective or high reflectivity device.

Abstract: An Echelle grating has alternate first (1a) and second (1b) sets of facets (1). The first set of facets (1a) is operative to reflect incident light (4) for diffraction and the second set of facets (1b) extends between adjacent facets of the first set (1a). Only the first set of facets (1a) is metallized to enhance reflection. The second set of facets (1b) is left unmetallized. This configuration reduces polarization dependent loss (PDL).

Abstract: The multichannel waveguide device includes an array of waveguides located in a plane. Each waveguide channel has a redirecting element for redirecting a guided wave out of said plane, or vice versa. The redirecting elements are staggered in the direction of the waveguides so as to transform a one-dimensional array of in-plane waves into a two-dimensional array of out-of-plane waves, or vice versa.

Abstract: A new and distinct cultivar of the muscadine grape plant, Vitis rotundifolia Michx., which has exceptionally good flavor, firm flesh texture with relatively thin skin, and a larger berry than the current grapes that are produced commercially. The vines of this cultivar are vigorous, productive and disease resistant.