Abstract: A compound of formula (I) capable of inhibiting plasmin activity, delaying fibrinolysis, and having coagulation and hemostatic activity, pharmaceutically acceptable salts, hydrates, isomers, prodrugs and mixtures thereof, wherein X, and R1 to R5 are as defined in the description.

Abstract: An array substrate including: a base substrate; a data line on the base substrate and extending in a first direction; and a touch signal line on the base substrate, wherein an extending direction of the touch signal line is the same as an extending direction of the data line; an orthographic projection of the touch signal line on the base substrate at least partially overlaps an orthographic projection of the data line on the base substrate, which is within an orthographic projection of a gap between two touch electrode units adjacent in a second direction on the base substrate, and a size of the data line in the second direction is smaller than a size, in the second direction, of the gap between the two touch electrode units adjacent in the second direction, where the second direction is perpendicular to the first direction.

Abstract: A driving and stabilization system for a pump laser, and a pump laser system. The driving and stabilization system includes a constant current stabilization device, a constant temperature stabilization device, a power detection device, an environment detection device, and a control device. The constant current stabilization device includes a voltage comparison circuit, a constant current driving circuit, and a switch protection circuit. The constant temperature stabilization device includes an internal constant temperature stabilization circuit and an external constant temperature stabilization circuit.

Abstract: The present disclosure provides methods and systems for profiling RNAs being translated in a cell. Also provided by the present disclosure are methods for diagnosing a disease or disorder in a subject based on a profile of the RNAs being translated in a cell, including cells within an intact tissue. Methods of screening for or testing a candidate agent capable of modulating translation of one or more RNAs are also provided by the present disclosure. The present disclosure also provides methods for treating a disease or disorder in a subject in need thereof. Pairs of probes and sets of probes comprising oligonuclcotide portions, which may be useful for performing the methods described herein, are also described by the present disclosure. Additionally, the present disclosure provides kits comprising any of the probes described herein.

Abstract: The present application provides a method and a device for charging and discharging a battery system, the battery system and an electric vehicle. The battery system includes a low-voltage battery and a high-voltage battery, the high-voltage battery and the low-voltage battery are both configured to be connected with a load. The method for charging and discharging the battery system includes steps of obtaining a first power of the load when the load is in operation; obtaining a first SOC value of the low-voltage battery and a second SOC value of the high-voltage battery; and controlling charge-and-discharge processes of the high-voltage battery and the low-voltage battery according to the first power, the first SOC value and the second SOC value.

Abstract: Disclosed herein are modified niRNAs and modified non-coding RNAs with poly(A) tails containing modified nucleotides and/or secondary structures, which may be made by ligation of a tailing nucleic acid onto the 3? terminal end of an RNA. Also provided are compositions comprising one or more modified mRNAs or modified non-coding RNAs provided herein, and methods of using said compositions for therapeutic or agricultural applications.

Abstract: A liquid crystal/polymer composite electrically controlled dimming film is provided, including a liquid crystal material, a polymer matrix, and two layers of conductive substrates. The polymer matrix is sandwiched between the two layers of conductive substrates, and the polymer matrix has a porous microstructure. The liquid crystal material is dispersed in the polymer matrix to form liquid crystal microdroplets, and the liquid crystal microdroplets have vertically oriented polymer networks. The liquid crystal/polymer composite electrically controlled dimming film has a unique composite microstructure. In this composite microstructure, the polymer matrix of the porous microstructure gives the film with good mechanical processing performance.

Abstract: The present application provides an array base plate and a light emitting apparatus, which relates to the technical field of displaying. The array base plate includes: a substrate; and a plurality of electrically-conductive-pad groups located on the substrate, wherein each of the electrically-conductive-pad groups includes at least one electrically conductive pad; the electrically conductive pad includes an electrically conducting layer and a first connecting layer, the first connecting layer is located on one side of the electrically conducting layer away from the substrate, and an orthographic projection of the first connecting layer on the substrate and an orthographic projection of the electrically conducting layer on the substrate at least partially intersect or overlap; and a thickness of the first connecting layer in a thickness direction of the substrate is greater than or equal to a thickness of the electrically conducting layer in the thickness direction of the substrate.

Abstract: The present disclosure provides methods for profiling spatiotemporal gene expression, including methods for profiling spatiotemporal gene expression in vivo in a subject. The present disclosure also provides methods for profiling the role of post-transcriptional modification in spatiotemporal gene expression, methods for studying the role of spatiotemporal gene expression in the development or progression of a disease or disorder, methods for screening for an agent capable of modulating spatiotemporal gene expression, methods for diagnosing a disease or disorder in a subject, and methods for treating a disease or disorder in a subject. Oligonucleotide probes useful in the methods described herein are also provided by the present disclosure. The present disclosure also provide kits comprising the oligonucleotide probes disclosed herein. Systems for profiling spatiotemporal gene expression are also provided by the present disclosure.

Abstract: A microfluidic system includes a matrix structure having a plurality of wells, each of the wells being accessible via at least one microfluidic path connectable via an interface to at least one droplet input for receiving one or more sets of droplets from one or more droplet sources, wherein a droplet enters a well based on one or more of: buoyancy, gravity, hydrodynamic force, and/or mechanical capturing, and wherein contents of a particular well are determinable based on a position of the particular well in the matrix structure and on inputs to the matrix structure. Methods using the matrix structure.

Abstract: An array substrate has a display area and a bonding region. The display area includes a distal region, a proximal region, and a middle region therebetween. The array substrate includes a base, a common electrode located in the display area, a connecting lead disposed outside the distal region, a conductive frame at least partially surrounding the display area, and at least one first common signal line, at least one second common signal line and at least one third common signal line. The first common signal line, the second common signal line and the third common signal line are respectively coupled to portions of the common electrode located in the distal region, the proximal region and the middle region. The first common signal line is coupled to the connecting lead. The connecting lead and the portion of the common electrode located in the distal region are coupled to the conductive frame.

Abstract: The embodiments of the present application provide a low-voltage power transmission system, a DCDC converter and a control method, a device and a medium, relating to the field of battery power. The control method includes: acquiring a charging signal; acquiring a vehicle start signal; acquiring an enabling signal; when each of the charging signal, the vehicle activating start signal, and the enabling signal is at a low level, and no communication message sent by a battery management system (BMS) is received, determining that a vehicle is in a power-off state and enters a sleep mode; when a duration of the sleep mode reaches a preset duration, performing self-awakening, and outputting, to the BMS, an awakening signal for awakening the BMS and making the BMS enter a working mode.

Abstract: A battery housing includes: a tray including a first channel; an explosion-proof valve disposed on the tray, the first channel being in communication with the explosion-proof valve; at least one module transverse beam disposed in the tray and including an accommodating portion, at least a part of a bottom of the accommodating portion being depressed downward to form a groove, and an opening disposed at at least one end of the groove along a length direction of the module transverse beam; and a liquid cooling plate connected to an outside of a bottom of the module transverse beam, at least one connection channel being formed between the liquid cooling plate and the module transverse beam, and the opening of the at least one module transverse beam being in communication with the first channel through the connection channel.

Abstract: A battery pack and an electric vehicle are provided. The battery pack includes a tray and a heating component. The heating component is arranged within the tray, and the heating component includes multiple heating sections. In the heating component of the battery pack, heating powers of the multiple heating sections are different, and the multiple heating sections are respectively configured to heat multiple regions within the tray to balance an ambient temperature within the tray.

Abstract: An array substrate including: a substrate; a data line on the base substrate and extending in a first direction; and a touch signal line on the base substrate, wherein an extending direction of the touch signal line is the same as an extending direction of the data line; the data line and the touch signal line are in different layers and insulated from each other, and an orthographic projection of the touch signal line on the base substrate at least partially overlaps an orthographic projection of the data line on the base substrate.

Abstract: The present application relates to the technical field of construction machinery, in particular to an excavator lower part length regulating system and an excavator. The excavator lower part length regulating system includes: a lower part walking beam; a caterpillar track, provided around the lower part walking beam; and a regulating assembly, adapted to regulating the length of the lower part walking beam and the height of the caterpillar track along a longitudinal direction. The regulating assembly has an extension state in which the lower part walking beam is driven to be elongated and the caterpillar track is driven to descend along a longitudinal direction, and a contraction state in which the lower part walking beam is driven to be shortened and the caterpillar track is driven to ascend along the longitudinal direction.

Abstract: This application provides a method, an apparatus, a system for detecting battery thermal runaway, and a battery management unit. The method includes: obtaining an output signal of an air pressure sensor located in a battery pack, and obtaining parameter information of the battery pack; determining state information of the air pressure sensor based on the output signal of the air pressure sensor; and generating an alarm signal indicating occurrence of thermal runaway in the battery pack based on the state information of the air pressure sensor and the parameter information of the battery pack. In this application, the thermal runaway detection for the battery pack may be implemented by considering parameter information of both the air pressure sensor and the battery pack, improving the reliability of the thermal runaway detection for the battery pack, reducing the probability of false positives and false negatives, and improving driving safety.

Abstract: Techniques for generating a dataset from a knowledge graph are described. An exemplary method includes receiving a request to generate a dataset from a knowledge graph to be stored in the storage; generating a dataset comprising a plurality of mention-concept pairs from the knowledge graph according to the request based one or more of a synonym-based and graph-based evaluation of the knowledge graph and a custom ontology for the knowledge graph; and storing the generated dataset in the storage.

Abstract: The present disclosure provides a self-similar regenerative amplification method and an apparatus. The apparatus includes a broadband seed source, a spectrum shaping broader, a self-similar regenerative amplifier and a pulse compressor disposed in order of a light path. The spectrum shaping broader includes a time domain broader and a spectrum shaper. The time domain broader is configured to broaden the seed pulses, and fine-tune a width of the seed pulse. The spectrum shaper is configured to perform spectrum shaping on the broadened pulses to obtain saddle chirped pulses. The pulse regenerative amplification component includes a gain crystal and a nonlinear crystal. The self-similar regenerative amplifier receives the saddle chirped pulses, performs multiple stepwise amplifications and multiple nonlinear spectrum broadenings back and forth on the saddle chirped pulses, and output high-energy chirped pulses to the pulse compressor.

Abstract: A cable modeling method and system, and an electronic device are provided. The method includes: acquiring preset cable attributes of a cable and a preset laying scenario of the cable; determining a start point, an end point and a path point of the cable according to the preset laying scenario; inputting the preset attributes of the cable, the start point, the end point, and the path point into an Autodesk Revit software to model the cable, thereby to obtain a cable simulation model; and laying the cable according to the cable simulation model. The method first determines a start point, an end point, and the path point of the cable through the preset laying scenario, and then inputs the preset attributes, the start point, the end point, and the path point into the Autodesk Revit software to model the cable, so as to obtain a cable simulation model.