Abstract: The applicants disclose a thin film magnetic media structure with a pre-seed layer of CrTiAl. The CrTiAl pre-seed layer presents an amorphous or nanocrystalline structure. The CrTiAl pre-seed layer improves in-plane c-axis orientation while maintaining a good orientation ratio. The pulse transition width (PW50) is narrowed and the soft error rate is improved. The preferred seed layer is RuAl.

Abstract: The present invention relates to an organic light emitting device (OLED) in which a binaphthalene derivative is used as the emissive layer and/or one or more of the charge transport layers, or as a host or dopant material for one or more of such layers.

Abstract: Melanin concentrating hormone receptor ligands (especially 1-benzyl-4-aryl-piperazines, 1-benzyl-4-aryl-piperidines and related compounds), capable of modulating MCH receptor activity, are provided. Such ligands may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).

Abstract: An electrical connector (1) includes a terminal module (32), a metallic shield (31) surrounding the terminal module, an outer dielectric cover (10) surrounding a major portion of the shield and a pair of a latching mechanism (50) attached to the cover. The terminal module includes a mating portion having a number of conductive terminals exposed therein. The shield includes a resilient latching beam (20) having a driving portion (22) and an outwardly latching portion (21). The latching mechanism includes a button (40) for deflecting the driving portion inwardly to urge the latching portion inwardly toward the mating portion, and a spring (46) and a spring assembled to the button and abutting against the shield for providing enough release strength to push the button to a normal position.

Abstract: A scan-based method for testing delay faults in a circuit comprising controlling a subset of state inputs of the circuit by a skewed-load approach and controlling all inputs other than said subset of state inputs by a broad-side approach.

Abstract: An interior blind spot mirror which is mounted on the pillar of the window frame inside a vehicle on the driver's side, or on the passenger's side, completely eliminates the blind spot. The interior blind spot mirror includes an extension serving as a bridge between the mirror and the base which can be removed from the extension. There are two ball joints on either end of the extension which enable a user to conveniently adjust the mirror to a desired position. The base includes a soft pad sandwiched between the base and the double stick foam adhesive so that the base can fit pillars of different shapes. The interior blind spot mirror also includes an alternative base constructed of soft material such as polymer which can be mounted on different shapes of pillars of the window frames without the soft pad being attached to the bottom of the base. There is a mounting box on top of the base having a U-shaped notch into which the joint box on the lower end of the extension can be slidably affixed.

Abstract: Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.

Abstract: The present invention discloses an apparatus and method for rapid analysis of members of a combinatorial library. The apparatus includes a plurality of vessels for containing individual library members and a fluid handling system that apportions a test fluid about equally between each of the vessels. This allows for simultaneous screening of library members by detecting changes in test fluid following contact with individual library members. Fluid flow through each of the vessels is controlled using passive flow restrictors or active flow controllers to ensure that each library member contacts approximately the same amount of test fluid per unit time. The disclosed apparatus is especially useful for screening library members based on their ability to catalyze the conversion of fluid reactants.

Abstract: The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.

Abstract: This invention provides aryl and heteroaryl compounds of Formula (I) as described herein, and methods of their preparation. Also provided are pharmaceutical compositions made with the compounds of Formula (I) and methods for making such compositions. Compounds of Formula (I) may be useful for treating viral infections including orthopox viruses, either alone or in combination with other therapeutic agents.

Abstract: The invention described herein relates to antibodies directed to the antigen phospholipase A2 (PLA2) and uses of such antibodies. In particular, in accordance with some embodiments of the invention, there are provided fully human monoclonal antibodies directed to the antigen PLA2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.

Abstract: This invention provides aryl and heteroaryl compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention may be antagonists, or partial antagonist of factor IX and/or factor XI and thus, may be useful for inhibiting the intrinsic pathway of blood coagulation. The compounds may be useful in a variety of applications including the management, treatment and/or control of diseases caused in part by the intrinsic clotting pathway.

Abstract: Techniques for delivering data for coordinating multiple party use of a facility include producing conditions data by measuring without human intervention current condition of a facility that is used by multiple human parties. Availability data that indicates present or future availability for the facility is generated based at least in part on the conditions data. Coordination data based at least in part on the availability data is presented for the parties. These techniques allow rapid dynamic adaptation to changing status of a high-value facility while being less reliant on varied and subjective human motivations for reporting status changes. Undue exposure of sensitive information can be avoided by deriving less detailed views from high-resolution images of the facility and its users. Coordination data can be projected directly onto, and manual input can be derived from, a magnetic white board currently used for coordination at many facilities.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: The invention relates to a pharmaceutical composition for treating siriasis and its process. The composition is formulated by Camphor, dried ginger, rhubarb, Common fennel, Chinese cinnamon, hot pepper and oleum eucalypti. According to the invention, the pharmaceutical composition can be taken conveniently and absorbed quickly. It has high contents of active ingredient, and accordingly it has a good therapeutic effect.

Abstract: An electronic connector (1) includes a dielectric housing (10), a number of terminals (20) received in the dielectric housing, a shell (30) mounted on the dielectric housing, a spacer (50) and a pair of ground plates (40). The dielectric housing includes a base (11), a pair of brackets (13) extending downwardly from opposite ends of the base. Each bracket has a shoulder (132) defining a retention slit (1322) extending therethrough. The ground plates are received in the retention slits. The shell has a pair of cantilever arms (33) received in the retention slits and electrically connecting with the ground plates.

Abstract: The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the measurement with ovarian cancer status. The invention further relates to kits for qualifying ovarian cancer status in a subject.

Abstract: Molecular systems are provided for electric field activated switches, such as optical switches. The molecular system has an electric field induced band gap change that occurs via one of the following mechanisms: (1) molecular conformation change; (2) change of extended conjugation via chemical bonding change to change the band gap; or (3) molecular folding or stretching. Nanometer-scale reversible optical switches are thus provided that can be assembled easily to make a variety of optical devices, including optical displays.

Abstract: A motor drive and a choke therefor are disclosed, wherein the choke comprises a magnetic core with an inner leg and two outer legs, and four coils, which may be connected in DC current paths in the motor drive. First and second differential coils are wound around first and second outer legs, respectively; and first and second common-mode coils are wound around the inner leg of the choke. The first and second differential coils smooth the DC current on a DC bus in the motor drive, and the first and second common-mode coils suppress common-mode voltages in the motor drive. Also disclosed is a method for suppressing common-mode voltages in a motor drive.

Abstract: This invention relates to treatment of papillomavirus infections. Primarily there is provided a method of treatment of an existing papillomavirus (PV) infection which includes the step of administration of PV VLPs selected from the group consisting of PV L1 VLPs and PV L1/L2 VLPs to a patient suffering from the PV infection. Suitably the PV infection is characterised by the presence of epithelial lesions. The major infection which is treated are gential warts caused by HPV 6 and HPV 11.