Patents by Inventor Xiao-Dong Yang

Xiao-Dong Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220031165
    Abstract: The present invention provides an imaging probe for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and optical coherence tomography. The imaging probes structures using high resolution imaging use combined high frequency ultrasound (IVUS) and optical imaging methods such as optical coherence tomography (OCT) and to accurate co-registering of images obtained from ultrasound image signals and optical image signals during scanning a region of interest.
    Type: Application
    Filed: October 18, 2021
    Publication date: February 3, 2022
    Inventors: Brian COURTNEY, Nigel Robert MUNCE, Amandeep Singh THIND, Victor Xiao Dong YANG, Francis Stuart FOSTER
  • Patent number: 11147452
    Abstract: The present invention provides an imaging probe for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and optical coherence tomography. The imaging probes structures using high resolution imaging use combined high frequency ultrasound (IVUS) and optical imaging methods such as optical coherence tomography (OCT) and to accurate co-registering of images obtained from ultrasound image signals and optical image signals during scanning a region of interest.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: October 19, 2021
    Assignee: SUNNYBROOK HEALTH SCIENCES CENTRE
    Inventors: Brian Courtney, Nigel Robert Munce, Amandeep Singh Thind, Victor Xiao Dong Yang, Francis Stuart Foster
  • Publication number: 20210249587
    Abstract: Disclosed herein is an apparatus and method for fine tuning properties of a thin film. The method of forming a piezoelectric film includes (a) depositing a first piezoelectric film layer on a surface of a substrate by a first physical vapor deposition (PVD) process. The method includes (b) depositing a second piezoelectric film layer, on top of and in contact with the first piezoelectric film layer, by a second PVD process. A temperature of the substrate is (c) reduced after forming the first piezoelectric film layer and before forming the second piezoelectric film layer. The temperature is reduced by performing a process for a first period of time. Processes (a), (b) and (c) are additionally performed one or more times. Process (c) is performed for a second period of time. The second period of time is different than the first period of time.
    Type: Application
    Filed: January 22, 2021
    Publication date: August 12, 2021
    Inventors: Lizhong SUN, Xiao Dong YANG
  • Publication number: 20210212772
    Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.
    Type: Application
    Filed: March 31, 2021
    Publication date: July 15, 2021
    Inventors: Victor Xiao Dong YANG, Beau Anthony Standish, Adrian Linus Dinesh Mariampillai, Michael Ka Kit Leung
  • Patent number: 10980601
    Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: April 20, 2021
    Assignee: RYERSON UNIVERSITY
    Inventors: Victor Xiao Dong Yang, Beau Anthony Standish, Adrian Linus Dinesh Mariampillai, Michael Ka Kit Leung
  • Publication number: 20200289086
    Abstract: The present invention provides scanning mechanisms for imaging probes using for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and/or optical coherence tomography. The imaging probes include adjustable rotational drive mechanism for imparting rotational motion to an imaging assembly containing either optical or ultrasound transducers which emit energy into the surrounding area. The imaging assembly includes a scanning mechanism having including a movable member configured to deliver the energy beam along a path out of said elongate hollow shaft at a variable angle with respect to said longitudinal axis to give forward and side viewing capability of the imaging assembly. The movable member is mounted in such a way that the variable angle is a function of the angular velocity of the imaging assembly.
    Type: Application
    Filed: June 1, 2020
    Publication date: September 17, 2020
    Inventors: Brian COURTNEY, Nigel Robert MUNCE, Amandeep Singh THIND, Victor Xiao Dong YANG, Francis Stuart FOSTER, Alan SOONG, Brian Heng LI
  • Patent number: 10667785
    Abstract: The present invention provides scanning mechanisms for imaging probes using for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and/or optical coherence tomography. The imaging probes include adjustable rotational drive mechanism for imparting rotational motion to an imaging assembly containing either optical or ultrasound transducers which emit energy into the surrounding area. The imaging assembly includes a scanning mechanism having including a movable member configured to deliver the energy beam along a path out of said elongate hollow shaft at a variable angle with respect to said longitudinal axis to give forward and side viewing capability of the imaging assembly. The movable member is mounted in such a way that the variable angle is a function of the angular velocity of the imaging assembly.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: June 2, 2020
    Assignee: SUNNYBROOK HEALTH SCIENCES CENTRE
    Inventors: Brian Courtney, Nigel Robert Munce, Amandeep Singh Thind, Victor Xiao Dong Yang, Francis Stuart Foster, Alan Soong, Brian Heng Li
  • Publication number: 20200062860
    Abstract: The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
    Type: Application
    Filed: November 4, 2019
    Publication date: February 27, 2020
    Inventors: Richard F. Weber, Xiao Feng, Orit Foord, Larry L. Green, Jean M. Gudas, Bruce A. Keyt, Ying Liu, Palaniswami Rathanaswami, Robert Raya, Xiao Dong Yang, Jose R.F. Corvalan, Ian Foltz, Xiao-Chi Jia, Jaspal Singh Kang, Chadwick Terence King, Scott L. Klakamp, Qiaojuan Jane Su
  • Patent number: 10508153
    Abstract: The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: December 17, 2019
    Assignee: Amgen Fremont Inc.
    Inventors: Richard F. Weber, Xiao Feng, Orit Foord, Larry L. Green, Jean M. Gudas, Bruce A. Keyt, Ying Liu, Palaniswami Rathanaswami, Robert Raya, Xiao Dong Yang, Jose R. F. Corvalan, Ian Foltz, Xiao-Chi Jia, Jaspal Singh Kang, Chadwick Terence King, Scott L. Klakamp, Qiaojuan Jane Su
  • Patent number: 10439410
    Abstract: Techniques pertaining to battery protection circuits are disclosed. According to one embodiment of the present invention, the battery protection circuit includes a power button, a power detection circuit, a first switch coupled between the power button and the power detection circuit, the power detection circuit configured to output a power-off signal when either the first switch or the power button is in a switch-off state, a low-voltage detection circuit coupled with a battery and configured to detect whether a voltage of the battery is lower than a low-voltage detection threshold or not, and switch off the first switch to cut off an electric leakage path of the battery when the voltage of the battery is determined to be lower than the low-voltage detection threshold, and a power management circuit coupled with the power detection circuit and configured to cut off an electric discharge path of the battery to prohibit the battery from discharging when receiving the power-off signal.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: October 8, 2019
    Assignee: Zgmicro Wuxi Corporation
    Inventors: Zhao Wang, David Xiao Dong Yang
  • Patent number: 10118968
    Abstract: The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: November 6, 2018
    Assignee: Amgen Fremont Inc.
    Inventors: Richard Weber, Xiao Feng, Orit Foord, Larry Green, Jean M. Gudas, Bruce Keyt, Ying Liu, Palaniswami Rathanaswami, Robert Raya, Xiao Dong Yang, Jose Corvalan, Ian Foltz, Xiao-Chi Jia, Jaspal S. Kang, Chadwick T. King, Scott L. Klakamp, Qiaojuan Jane Su
  • Patent number: 10066011
    Abstract: Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: September 4, 2018
    Assignee: MedImmune Limited
    Inventors: Larry L. Green, Qing Zhou, Bruce A. Keyt, Xiao-Dong Yang, Stephen Charles Emery, David Charles Blakey
  • Publication number: 20180153626
    Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.
    Type: Application
    Filed: January 30, 2018
    Publication date: June 7, 2018
    Inventors: Victor Xiao Dong YANG, Beau Anthony Standish, Adrian Linus Dinesh Mariampillai, Michael Ka Kit Leung
  • Patent number: 9901409
    Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: February 27, 2018
    Assignee: RYERSON UNIVERSITY
    Inventors: Victor Xiao Dong Yang, Beau Anthony Standish, Adrian Linus Dinesh Mariampillai, Michael Ka Kit Leung
  • Patent number: 9796779
    Abstract: Binding proteins, such as antibodies directed to IGF-II with cross-reactivity to IGF-I and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the IGF-II with cross-reactivity to IGF-I are disclosed. Also discussed are nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: October 24, 2017
    Assignee: MedImmune Limited
    Inventors: Olivia Raeber, Gadi Gazit-Bornstein, Xiao-Dong Yang, Susan Ann Cartlidge, David William Tonge
  • Publication number: 20170042622
    Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.
    Type: Application
    Filed: November 1, 2016
    Publication date: February 16, 2017
    Inventors: Victor Xiao Dong YANG, Beau Anthony Standish, Adrian Linus Dinesh Mariampillai, Michael Ka Kit LEUNG
  • Patent number: 9510914
    Abstract: Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: December 6, 2016
    Assignee: Ryerson University
    Inventors: Victor Xiao Dong Yang, Beau Anthony Standish, Adrian Linus Dinesh Mariampillai, Michael Ka Kit Leung
  • Patent number: 9497317
    Abstract: Techniques for a personalized Bluetooth headset and a voice interaction control method thereof are described. According to one aspect of the present invention, the Bluetooth headset is configured to create and maintain a voice-based table. Each item in the table includes a phone number paired with a set of audio data (e.g., a voice or a predefined audio), where the audio data is created by a user. When a paired mobile device receives a call, the table is searched per the caller number. A corresponding audio is played back first when an item is located in the table. As such a user of the Bluetooth headset knows who is calling and determines whether the call shall be answered or not.
    Type: Grant
    Filed: October 19, 2014
    Date of Patent: November 15, 2016
    Assignee: WUXI VIMICRO CORPORATION
    Inventors: David Xiao Dong Yang, Jian Chen, Feng Zhu, Yuhong Feng
  • Publication number: 20160302763
    Abstract: The present invention provides scanning mechanisms for imaging probes using for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and/or optical coherence tomography. The imaging probes include adjustable rotational drive mechanism for imparting rotational motion to an imaging assembly containing either optical or ultrasound transducers which emit energy into the surrounding area. The imaging assembly includes a scanning mechanism having including a movable member configured to deliver the energy beam along a path out of said elongate hollow shaft at a variable angle with respect to said longitudinal axis to give forward and side viewing capability of the imaging assembly. The movable member is mounted in such a way that the variable angle is a function of the angular velocity of the imaging assembly.
    Type: Application
    Filed: June 24, 2016
    Publication date: October 20, 2016
    Inventors: Brian COURTNEY, Nigel Robert MUNCE, Amandeep Singh THIND, Victor Xiao Dong YANG, Francis Stuart FOSTER, Alan SOONG, Brian Heng LI
  • Patent number: 9375147
    Abstract: The present invention provides scanning mechanisms for imaging probes using for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and/or optical coherence tomography. The imaging probes include adjustable rotational drive mechanism for imparting rotational motion to an imaging assembly containing either optical or ultrasound transducers which emit energy into the surrounding area. The imaging assembly includes a scanning mechanism having including a movable member configured to deliver the energy beam along a path out of an elongate hollow shaft at a variable angle with respect to the longitudinal axis to give forward and side viewing capability of the imaging assembly. The movable member is mounted in such a way that the variable angle is a function of the angular velocity of the imaging assembly.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: June 28, 2016
    Assignee: SUNNYBROOK HEALTH SCIENCES CENTRE
    Inventors: Brian Courtney, Nigel Robert Munce, Amandeep Singh Thind, Victor Xiao Dong Yang, Francis Stuart Foster, Alan Soong, Brian Heng Li