Abstract: An illumination system with freeform surface comprises a plurality of collimated light sources having same parameters and a freeform surface lens comprising a first freeform surface and a second freeform surface, wherein formula of the first freeform surface and the second freeform surface is expressed as follows: z = c ? ( x 2 + y ? ? 2 ) 1 + 1 - ( 1 + k ) ? c 2 ? ( x 2 + y 2 ) + ? m ? ? n ? A mn ? x m ? y n , in which c is the curvature of the conic surface at the vertex, k is the conic constant, Amn represents the xy polynomials coefficient, m+n?2 and both m and n are even, beams emitted by the plurality of collimated light sources pass through the freeform surface lens to form a plurality of light spots on a target plane.

Abstract: An inhibitor of a wild type and Y641 F mutant of human histone methyltransferase EZH2 is provided herein. Particularly, the inhibitor is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The inhibitor can be used to treat a cancer or precancerous condition related to EZH2 activity.

Abstract: An underbody panel for a motor vehicle, in particular a passenger vehicle, has at least one first underbody panel element which is arranged in a region of a pivotable vehicle wheel and moves with the wheel during a pivoting movement of the wheel and at least one second underbody panel element which is arranged in the region of the wheel and which is pivotable with the wheel during a pivoting movement of the wheel in the opposite direction.

Abstract: A method for designing off-axial optical system with freeform surfaces is provided. An initial system is established. A freeform surface of the off-axial optical system that needs to be solved is defined as a freeform surface. A number of feature rays are selected. A number of intersections of the feature rays with the freeform surface are calculated point by point based on a given object-image relationship and a vector form of Snell's law. A number of first feature data points are obtained from the intersections and surface fitted to obtain the freeform surface. All the freeform surfaces of the off-axial optical system that need to be solved are obtained by the method above to form a before-iteration off-axial optical system. The before-iteration off-axial optical system is used as the initial system for multiple iterations to obtain an after-iteration off-axial optical system.

Abstract: A method for designing three-dimensional freeform surface is provided. An initial surface and a first three-dimensional rectangular coordinates system are established. A number of feature rays are selected. A number of intersections of the feature rays with a first freeform surface are calculated, wherein the intersections are a number of feature data points. The first freeform surface is obtained by surface fitting the feature data points. An equation of the first freeform surface includes a conic term and a freeform surface term. The first freeform surface is taken as the initial surface for an iteration process.

Abstract: A method for analyzing distribution of tolerances on a freeform surface in an optical system. Establishes a freeform surface imaging optical system. A plurality of fields is selected, and maximum and minimum margins of wavefront errors in each field are defined. One freeform surface in one field is selected, an isolated point jumping model is established, and an isolated point is placed in different areas of the freeform surface of the one field. A local figure error with extreme values corresponding to each field is resolved, based on the maximum and minimum margins of wavefront erroes, and the local surface tolerance distributions of the freeform surface in the plurality of fields are integrated together.

Abstract: A design method of LED freeform surface illumination system based on XY-polynomial obtains a plurality of data points of a freeform surface, wherein each data point includes a coordinate value Qi and a normal vector Ni. A sum of squares e1(P) of coordinate differences in z direction between the coordinate value Qi and the freeform surface is applied, and by a sum of squares e2(P) between the normal vector Ni of the data points and normal vector ni of the freeform surface a modulus of vector differences is acquired. An evaluation function ƒ(p)=e1(P)+we2(P) is proposed and a plurality of freeform surface shapes obtained by selecting different weightings. The freeform surface shape which has the best imaging quality is achieved as a final shape, and a freeform surface lens based on the final shape is constructed to establish an LED freeform surface illumination system.

Abstract: An initial system and a constraint condition are established. All freeform surfaces are obtained by surface fitting the feature data points to form a first freeform surface imaging optical system. The first freeform surface imaging optical system is taken as the initial system for multiple iterations to obtain a second freeform surface imaging optical system. The second freeform surface imaging optical system is taken as a first base system. A first surface freedom of the first base system is selected, the values nearby the first surface freedom is selected, and surface positions and tilts of the first base system are changed to obtain a third freeform surface imaging optical system that satisfies the constraint condition. A second base system is selected and the method above is repeated. The freeform surface imaging optical system is obtained until all freedoms for surface positions and tilts have been used.

Abstract: An illumination system with freeform surface comprises a plurality of collimated light sources having same parameters and a freeform surface lens comprising a first freeform surface and a second freeform surface, wherein formula of the first freeform surface and the second freeform surface is expressed as follows: z = c ? ( x 2 + y ? ? 2 ) 1 + 1 - ( 1 + k ) ? c 2 ? ( x 2 + y 2 ) + ? m ? ? n ? A mn ? x m ? y n , in which c is the curvature of the conic surface at the vertex, k is the conic constant, Amn represents the xy polynomials coefficient, m+n?2 and both m and n are even, beams emitted by the plurality of collimated light sources pass through the freeform surface lens to form a plurality of light spots on a target plane.

Abstract: A method for designing illumination system with freeform surface, the method comprising: presupposing a plurality of expected light spots; establishing an initial system, wherein the initial system comprises a plurality of collimated light sources, a plane lens and a target plane; designing a sphere lens to replace the plane lens, and obtaining a before-construction-iteration illumination system; selecting a plurality of feature rays and obtaining a plurality of target points; taking the before-construction-iteration illumination system as an initial construction-iteration system, and obtaining an after-construction-iteration illumination system with freeform surface by making multiple construction-iteration, wherein the illumination system with freeform surface is configured to form the plurality of expected light spots.

Abstract: An initial system and a constraint condition are established. All freeform surfaces are obtained by surface fitting the feature data points to form a first freeform surface imaging optical system. The first freeform surface imaging optical system is taken as the initial system for multiple iterations to obtain a second freeform surface imaging optical system. The second freeform surface imaging optical system is taken as a first base system. A first surface freedom of the first base system is selected, the values nearby the first surface freedom is selected, and surface positions and tilts of the first base system are changed to obtain a third freeform surface imaging optical system that satisfies the constraint condition. A second base system is selected and the method above is repeated. The freeform surface imaging optical system is obtained until all freedoms for surface positions and tilts have been used.

Abstract: An underbody panel for a motor vehicle, in particular a passenger vehicle, has at least one first underbody panel element which is arranged in a region of a pivotable vehicle wheel and moves with the wheel during a pivoting movement of the wheel and at least one second underbody panel element which is arranged in the region of the wheel and which is pivotable with the wheel during a pivoting movement of the wheel in the opposite direction.

Abstract: A manufacturing method of a semiconductor structure is provided. The manufacturing method of the semiconductor structure includes the following steps: providing a semiconductor substrate, wherein the semiconductor substrate has a first region and a second region surrounding the first region; forming a gate stack and a dummy gate stack in the first region, wherein the dummy gate stack surrounds the gate stack; forming an oxide layer on an exterior wall and a top surface of the dummy gate stack; forming a dummy conductive layer on the gate stack, the dummy gate stack and the oxide layer, wherein the dummy conductive layer has a concave bowl-shaped top surface in the first region; and performing a chemical mechanical polishing (CMP) process on the dummy conductive layer.

Abstract: A methods and device for accessing virtual machine (VM) data are described. A computing device for accessing virtual machine comprises an access request process module, a data transfer proxy module and a virtual disk. The access request process module receives a data access request sent by a VM and adds the data access request to a request array. The data transfer proxy module obtains the data access request from the request array, maps the obtained data access request to a corresponding virtual storage unit, and maps the virtual storage unit to a corresponding physical storage unit of a distributed storage system. A corresponding data access operation may be performed based on a type of the data access request.

Abstract: A construction method of freeform surface shape based on XY-polynomial obtains a plurality of data points of a freeform surface according to an object point and an imaging point in a three-dimensional Cartesian coordinates system Oxyz. Each of the plurality of data points comprises a coordinate value Qi and a normal vector Ni. A first sum of squares e1(P) of coordinate differences in z direction between the coordinate value Qi and the freeform surface is applied, and by a second sum of squares e2(P) between the normal vector Ni of the data points and a normal vector ni of the freeform surface, a modulus of vector differences is acquired. An evaluation function ƒ(p)=e1(P)+we2(P) is proposed and a plurality of freeform surface shapes obtained by selecting and applying different weightings. A final freeform surface shape ?opt is chosen from the plurality of freeform surface shapes.

Abstract: A server receives a request to upload a file form a user device. The server may generate a unique file ID associated with the file based on the request, and transmit the file ID to the user device. The user device may divide the file to generate multiple slice files and their corresponding slice IDs. From the user device, the server receives the multiple slice files and the slice IDs. Based on the slice IDs, the server may determine storage addresses at which to store the multiple slice files in a distributed storage system using a consistent hash algorithm. The multiple slice files may be stored based on the corresponding storage addresses of the distrusted storage system.

Abstract: A method is disclosed. The method includes determining a touch control parameter of a touch control operation at an identifier corresponding to an application program. The method also includes determining a touch control type based on the touch control parameter. The method also includes invoking a first element related to the application program in response to a determination that the touch control operation is a first type of touch control. The method also includes invoking a second element related to the application program in response to a determination that the touch control operation is a second type of touch control.

Abstract: The present invention relates to a pharmaceutical composition for treating and preventing degenerative neurological disorders, containing, as an active ingredient, a mixture extract of two or more types selected from the group consisting of Moutan Root Bark, Angelica Dahurica Root, and Bupleurum Root, or a fraction thereof.

Abstract: A methods and device for accessing virtual machine (VM) data are described. A computing device for accessing virtual machine comprises an access request process module, a data transfer proxy module and a virtual disk. The access request process module receives a data access request sent by a VM and adds the data access request to a request array. The data transfer proxy module obtains the data access request from the request array, maps the obtained data access request to a corresponding virtual storage unit, and maps the virtual storage unit to a corresponding physical storage unit of a distributed storage system. A corresponding data access operation may be performed based on a type of the data access request.

Abstract: A packing box can include a first cover, a second cover, a first sidewall, a second sidewall, a third sidewall, a fourth sidewall, and a bulkhead. The first cover and the second cover can be opposite to each other. The four sidewalls can be sequentially coupled end-to-end. The bulkhead can be received in the main box and be substantially parallel to the first cover and the second cover. Four edges of the bulkhead can be coupled to the four sidewalls, respectively. An inner receiving space of the main box can be divided into a first receiving cavity and a second receiving cavity by the bulkhead. A number of receiving portions can be defined on a surface of the packing box facing the first receiving cavity.