Patents by Inventor Xiao Hong
Xiao Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11883148Abstract: A system and method for performing magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), or magnetic resonance spectroscopy imaging (MRSI) at multiple resonant frequencies using a coil system. The coil system includes at least one conductive loop and a capacitor forming a radiofrequency (RF) resonant antenna and a tuning-matching circuit electrically connected to the RF resonant antenna to operate at multiple resonant frequencies across a desired operational range. The coil system also includes two legs electrically connecting the tuning-matching circuit to the RF resonant antenna and having a length selected to generate at least two selected resonant frequencies with a selected frequency difference.Type: GrantFiled: July 25, 2022Date of Patent: January 30, 2024Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Wei Chen, Guangle Zhang, Wei Zhu, Xiao-Hong Zhu
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Publication number: 20230212604Abstract: A method for gene editing in a vertebrate brain comprising: intravascular administration of a brain penetrable viral vector including a target sequence in a genomic locus of interest and a CRISPR enzyme; genomic integration via Non-Homologues End Joining (NHEJ) in post-mitotic neurons; and editing a monopartite cell-type specific gene via NHEJ knock-in a sgRNA flanked by self-cleaving ribozymes into 3?UTR to use an endogenous promoter for sgRNA expression.Type: ApplicationFiled: December 11, 2019Publication date: July 6, 2023Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Xiao-Hong LU, Xinli TIAN
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Publication number: 20230190129Abstract: A system and method for performing magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), or magnetic resonance spectroscopy imaging (MRS I) at multiple resonant frequencies using a coil system. The coil system includes at least one conductive loop and a capacitor forming a radiofrequency (RF) resonant antenna and a tuning-matching circuit electrically connected to the RF resonant antenna to operate at multiple resonant frequencies across a desired operational range. The coil system also includes two legs electrically connecting the tuning-matching circuit to the RF resonant antenna and having a length selected to generate at least two selected resonant frequencies with a selected frequency difference.Type: ApplicationFiled: July 25, 2022Publication date: June 22, 2023Applicant: Regents of the University of MinnesotaInventors: Wei Chen, Guangle Zhang, Wei Zhu, Xiao-Hong Zhu
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Publication number: 20230069973Abstract: A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue.Type: ApplicationFiled: August 16, 2022Publication date: March 9, 2023Inventors: Corey Edward Cruttenden, Rajesh Rajamani, Wei Chen, Xiao-Hong Zhu, Mahdi Ahmadi
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Patent number: 11533027Abstract: Data isolators are described. The data isolators include a differential receiver having cross-coupled single-ended amplifiers. The single-ended amplifiers may be referenced to a time-varying reference potential. The cross-coupling of the single-ended amplifiers may provide high speed, low power consumption operation of the data isolator.Type: GrantFiled: October 18, 2019Date of Patent: December 20, 2022Assignee: Analog Devices, Inc.Inventor: Xiao Hong Du
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Patent number: 11527605Abstract: A method for fabricating a MOMCAP includes steps as follows: An Nth metal layer is formed on a substrate according to an Nth expected capacitance value of the Nth metal layer. An Nth capacitance error value between an Nth actual capacitance value of the Nth metal layer and the Nth expected capacitance value is calculated. An N+1th expected capacitance value of an N+1th metal layer is adjusted to form an N+1th actual capacitance value according to the Nth capacitance error value, and the N+1th metal layer with an N+1th actual capacitance value is formed on the Nth metal layer according to the adjusted N+1th expected capacitance value, to make the sum of the Nth actual capacitance value and the N+1th actual capacitance value equal to the sum of the Nth expected capacitance value and the N+1th expected capacitance value. N is an integer greater than 1.Type: GrantFiled: July 1, 2021Date of Patent: December 13, 2022Assignee: UNITED MICROELECTRONICS CORP.Inventors: Shu-Ji Chen, Jing Feng, Xiao-Hong Jiang, Ching-Hwa Tey
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Publication number: 20220367609Abstract: A method for fabricating a MOMCAP includes steps as follows: An Nth metal layer is formed on a substrate according to an Nth expected capacitance value of the Nth metal layer. An Nth capacitance error value between an Nth actual capacitance value of the Nth metal layer and the Nth expected capacitance value is calculated. An N+1th expected capacitance value of an N+1th metal layer is adjusted to form an N+1th actual capacitance value according to the Nth capacitance error value, and the N+1th metal layer with an N+1th actual capacitance value is formed on the Nth metal layer according to the adjusted N+1th expected capacitance value, to make the sum of the Nth actual capacitance value and the N+1th actual capacitance value equal to the sum of the Nth expected capacitance value and the N+1th expected capacitance value. N is an integer greater than 1.Type: ApplicationFiled: July 1, 2021Publication date: November 17, 2022Inventors: Shu-Ji CHEN, Jing FENG, Xiao-Hong JIANG, Ching-Hwa TEY
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Patent number: 11439810Abstract: A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue.Type: GrantFiled: July 18, 2018Date of Patent: September 13, 2022Assignee: Regents of the University of MinnesotaInventors: Corey Edward Cruttenden, Rajesh Rajamani, Wei Chen, Xiao-Hong Zhu, Mahdi Ahmadi
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Patent number: 11275132Abstract: An apparatus for transmitting and receiving radiofrequency (RF) signals in a magnetic resonance imaging system for proton and X-nuclear imaging includes at least one radiofrequency (RF) coil and an ultrahigh dielectric constant material incorporated within the at least one RF coil. The permittivity of the ultrahigh dielectric constant material depends on a temperature of the material and is tunable. The apparatus also includes a temperature controller that is thermally coupled to the ultrahigh dielectric constant material. The temperature controller is configured to control a temperature of the ultrahigh dielectric constant material to tune and optimize the permittivity of the ultrahigh dielectric constant material. A chemical structure and composition of the ultrahigh dielectric constant material is selected to control and optimize the permittivity and a dielectric loss of the ultrahigh dielectric constant material and a temperature dependence of the ultrahigh dielectric constant material.Type: GrantFiled: April 8, 2020Date of Patent: March 15, 2022Assignees: REGENTS OF THE UNIVERSITY OF MINNESOTA, The Penn State Research FoundationInventors: Wei Chen, Byeong-Yeul Lee, Xiao-Hong Zhu, Hannes M. Wiesner, Michael T. Lanagan, Qing X. Yang, Sebastian Rupprecht, Navid P. Gandji, Maryam Sarkarat
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Publication number: 20220056024Abstract: Provided herein are compounds that can inhibit the replication of influenza viruses, reduce the amount of influenza viruses, and/or treat influenza.Type: ApplicationFiled: September 10, 2019Publication date: February 24, 2022Inventors: IRINA C. JACOBSON, Biing Yuan Lin, Emiliano J. Sanchez, Sam SK Lee, Xiao Hong
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Patent number: 11171602Abstract: The disclosure discloses an RC oscillating circuit. A first end of a capacitor is grounded, a second end of the capacitor is connected to a charging path, a discharging path and a comparator, A first input end of a comparator is connected to first reference voltage. An output end of the comparator outputs a first output signal and is connected to a control end of the discharging path. The first reference voltage provides the flipped voltage of the comparator The first output signal forms an output clock signal. A first regulating circuit is configured to regulate the magnitude of the charging current and realize coarse frequency tuning. A second regulating circuit is configured to regulate the magnitude of the first reference voltage and realize fine frequency tuning. The disclosure has the advantages of low power consumption, fast start, high precision and wide tuning range.Type: GrantFiled: June 26, 2020Date of Patent: November 9, 2021Assignee: Shanghai Huahong Grace Semiconductor Manufacturing CorporationInventor: Xiao Hong
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Patent number: 11052450Abstract: A spring forming machine having tool rotation and tool retraction capabilities, that includes: a rotary beak seat mechanism and a dual-transmission core rotation separation mechanism. The rotary beak seat mechanism is installed on a transmission mechanism of an outside machine panel board through a panel board bearing. The rotary beak seat mechanism includes a rotation component, that rotates 360 degrees around a central axis of the panel board bearing. On a front end of the rotation component is disposed a slide seat component coaxially. The dual-transmission core rotation separation mechanism includes: a first substrate, in a center of a front plate surface of the first substrate is disposed the rotary beak seat mechanism, on a back plate surface of the first substrate is disposed an axle core positioning mechanism, an inner circle core rotation transmission mechanism, and an outer circle tool rotation transmission mechanism.Type: GrantFiled: October 13, 2019Date of Patent: July 6, 2021Assignee: HUIZHOU ODMAY MACHINERY CO., LTD.Inventors: Song-Wei Ye, Xiao-Hong Zhou, Jian-Ming Long
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Publication number: 20210119590Abstract: Data isolators are described. The data isolators include a differential receiver having cross-coupled single-ended amplifiers. The single-ended amplifiers may be referenced to a time-varying reference potential. The cross-coupling of the single-ended amplifiers may provide high speed, low power consumption operation of the data isolator.Type: ApplicationFiled: October 18, 2019Publication date: April 22, 2021Applicant: Analog Devices, Inc.Inventor: Xiao Hong Du
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Publication number: 20210078932Abstract: The present disclosure discloses a novel compound, 3,4-dihydroxyphenethyl 3-hydroxybutanoate, a method for preparing the same and use of the same, and in particular, a compound of formula I, use of the compound of formula I, optically pure isomers of the compound, a mixture of enantiomers in any ratio, or pharmaceutically acceptable salts thereof in preparing health food and drug for relieving brain fatigue, improving learning and memory abilities, and ameliorating mania mood related to brain fatigue.Type: ApplicationFiled: September 5, 2020Publication date: March 18, 2021Inventors: JIAN-GANG LONG, YA-CHONG HU, YONG-YAO WANG, ZHEN WANG, QING-QING MA, YU-XIA ZHANG, QING-LIN JIANG, XIAO-HONG XU, TING-HUA ZHANG, JIAN-KANG LIU
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Patent number: 10947179Abstract: The disclosure relates to a compound, 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate, for improving aortic endothelial cell function and use thereof. The compound is capable of inhibiting inflammatory response of the human aortic endothelial cells caused by a saturated fatty acid, and preventing an occurrence and progression of atherosclerosis. The compound is capable of reducing human aortic endothelial inflammation caused by a saturated fatty acid, for example, reducing the mRNA levels of interleukin-6 (IL-6), and is capable of effectively protecting the function of mitochondria in human aortic endothelium from being damaged by a saturated fatty acid, for example, increasing the expression of mitochondrial complex I.Type: GrantFiled: September 26, 2019Date of Patent: March 16, 2021Assignee: XI'AN JIAOTONG UNIVERSITYInventors: Jian-Kang Liu, Xu-Yun Liu, Ya-Chong Hu, Lin Zhao, Yong-Yao Wang, Cai-Yue Zhu, Zhen Wang, Jing Lou, Qing-Qing Ma, Yu-Xia Zhang, Qing-Lin Jiang, Xiao-Hong Xu, Ting-Hua Zhang, Jian-Gang Long
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Patent number: 10929083Abstract: A resource sharing device and control method thereof. The resource sharing device is electrically coupled to a plurality of computers and a mouse. The mouse is used to control a mouse cursor, and each computer is electrically coupled to a display. The steps include: identifying the spatial arrangement and resolutions of the displays; the computers initializing the respective positions of the mouse cursor; receiving a mouse displacement generated by the mouse; generating a mouse cursor displacement according to the mouse displacement and an acceleration setting; transmitting the mouse cursor displacement to one of the computers; determining whether the mouse cursor reaches a threshold; when the determination is affirmative, switching the mouse control to another computer.Type: GrantFiled: December 28, 2018Date of Patent: February 23, 2021Assignee: ATEN International Co., Ltd.Inventors: Xiao-Hong Wang, Xing Hong, Sung-Ting Dai
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Publication number: 20210047262Abstract: The disclosure relates to a compound, 2-(3,4-dihydroxyphenyl)ethyl 3-hydroxybutanoate, for improving aortic endothelial cell function and use thereof. The compound is capable of inhibiting inflammatory response of the human aortic endothelial cells caused by a saturated fatty acid, and preventing an occurrence and progression of atherosclerosis. The compound is capable of reducing human aortic endothelial inflammation caused by a saturated fatty acid, for example, reducing the mRNA levels of interleukin-6 (IL-6), and is capable of effectively protecting the function of mitochondria in human aortic endothelium from being damaged by a saturated fatty acid, for example, increasing the expression of mitochondrial complex I.Type: ApplicationFiled: September 26, 2019Publication date: February 18, 2021Applicant: XI'AN JIAOTONG UNIVERSITYInventors: JIAN-KANG LIU, XU-YUN LIU, YA-CHONG HU, LIN ZHAO, YONG-YAO WANG, CAI-YUE ZHU, ZHEN WANG, JING LOU, QING-QING MA, YU-XIA ZHANG, QING-LIN JIANG, XIAO-HONG XU, TING-HUA ZHANG, JIAN-GANG LONG
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Publication number: 20210036660Abstract: The disclosure discloses an RC oscillating circuit. A first end of a capacitor is grounded, a second end of the capacitor is connected to a charging path, a discharging path and a comparator, A first input end of a comparator is connected to first reference voltage. An output end of the comparator outputs a first output signal and is connected to a control end of the discharging path. The first reference voltage provides the flipped voltage of the comparator The first output signal forms an output clock signal. A first regulating circuit is configured to regulate the magnitude of the charging current and realize coarse frequency tuning. A second regulating circuit is configured to regulate the magnitude of the first reference voltage and realize fine frequency tuning. The disclosure has the advantages of low power consumption, fast start, high precision and wide tuning range.Type: ApplicationFiled: June 26, 2020Publication date: February 4, 2021Applicant: SHANGHAI HUAHONG GRACE SEMICONDUCTOR MANUFACTURING CORPORATIONInventor: Xiao HONG
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Patent number: 10819042Abstract: A broadband low-profile dual-linearly polarized antenna for a OneLTE two-in-one platform and an antenna array device formed therefrom are provided that can realize low-profile and ultra-broadband and have such advantages as simple structure, neat appearance, easy engineering implementation, and suitability for mass production. The broadband low-profile dual-linearly polarized antenna can include (1) a radiating portion that can include a dielectric substrate, printed folded dipoles spaced apart on an upper surface of the dielectric substrate, first coupled parasitic elements on a lower surface of the dielectric substrate, and second coupled parasitic elements on the upper surface of the dielectric substrate and (2) a feed balun for feeding the radiating portion, wherein each of the printed folded dipoles can include a corresponding one of the first coupled parasitic elements and a corresponding one of the second coupled parasitic elements.Type: GrantFiled: September 6, 2018Date of Patent: October 27, 2020Assignee: PC-TEL, INC.Inventors: Xiao Hong Xia, Ma Chang Ming
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Publication number: 20200319275Abstract: An apparatus for transmitting and receiving radiofrequency (RF) signals in a magnetic resonance imaging system for proton and X-nuclear imaging includes at least one radiofrequency (RF) coil and an ultrahigh dielectric constant material incorporated within the at least one RF coil. The permittivity of the ultrahigh dielectric constant material depends on a temperature of the material and is tunable. The apparatus also includes a temperature controller that is thermally coupled to the ultrahigh dielectric constant material. The temperature controller is configured to control a temperature of the ultrahigh dielectric constant material to tune and optimize the permittivity of the ultrahigh dielectric constant material. A chemical structure and composition of the ultrahigh dielectric constant material is selected to control and optimize the permittivity and a dielectric loss of the ultrahigh dielectric constant material and a temperature dependence of the ultrahigh dielectric constant material.Type: ApplicationFiled: April 8, 2020Publication date: October 8, 2020Inventors: Wei Chen, Byeong-Yeul Lee, Xiao-Hong Zhu, Hannes M. Wiesner, Michael T. Lanagan, Qing X. Yang, Sebastian Rupprecht, Navid P. Gandji, Maryam Sarkarat