Abstract: Provided is an engineered polypeptide capable of catalyzing the asymmetric hydrolysis of 3-isobutylglutarimide to generate (R)-(?)-3-(carbamoylmethyl)-5-methylhexanoic acid. The engineered polypeptide has high stereoselectivity, high catalytic activity, good process stability and thermal stability, and tolerance to high product concentrations, and has good prospects for industrial applications.

Abstract: Disclosed is NOR memory device. The NOR memory device comprises: at least two source/drain contact layers and at least one isolation layer alternately stacked in a vertical direction; a gate structure vertically extending through the source/drain contact layers and the isolation layer; and a semiconductor layer on the periphery of the gate structure; wherein, two of the source/drain contact layers located immediately above and below the isolation layer are respectively connected to two bit/source lines, and form a memory transistor together with the gate structure and the semiconductor layer.

Abstract: The present disclosure provides an energy transmission method, an energy router and an operation control device thereof, and a storage medium, and relates to the field of energy network technology. The energy router of the present disclosure includes a plurality of ports configured to perform at least one of receiving or sending energy and PLC data, energy transmission switches, each of the energy transmission switches is configured to control open and closed states of one port of, and a routing processor configured to determine an energy transmission path according to the PLC data and stored routing information, determine a corresponding port associated with the energy transmission path, and turn on an energy transmission switch of the corresponding port, for the energy outputting from the corresponding port.

Abstract: This application provides a method for adjusting display screen brightness, an electronic device, and a storage medium. The method includes: setting display screen brightness in response to an automatic brightness setting instruction; adjusting the display screen brightness in response to a brightness setting instruction generated by manually adjusting brightness by a user; determining, when a display screen is on again after the display screen is off, whether a mechanism of clearing the display screen brightness manually adjusted is triggered; if the mechanism of clearing the display screen brightness manually adjusted is triggered, setting the display screen brightness again in response to the automatic brightness setting instruction; determining, in response to an operation of manually adjusting the display screen brightness again, whether the operation of manually adjusting the display screen brightness again is the same as a previous operation of manually adjusting the display screen brightness.

Abstract: The application provides a structured light module and an autonomous mobile device. The structured light module includes a first camera and line laser emitters for collecting a first environmental image containing laser stripes generated when the line laser encounters an object. The structured light module can also capture a visible light image through a second environmental image that does not contain laser stripes. Both the first and second environmental images can help to detect more accurate and richer environmental information, expanding the application range of laser sensors.

Abstract: The present invention provides ketoreductase variants having activity on both (R)-(?)-1,3-butanediol and (S)-(+)-1,3-butanediol, and the computational methodology for designing the above mentioned ketoreductase variants. The ketoreductase variants disclosed in the present application can catalyze the reaction of synthesizing 4-hydroxy-2-butanone from racemic 1,3-butanediol, which has industrial application prospects.

Abstract: An energy Internet system, an energy routing conversion device, and an energy control method, relating to a field of energy information. An alternating-current (AC) side energy routing conversion device of the energy Internet system includes a plurality of first route ports, and a direct-current (DC) side energy routing conversion device includes a plurality of second route ports, where each second route port is connected to a corresponding first route port by means of a corresponding DC busbar. A plurality of energy devices are connected to a DC busbar by means of corresponding first AC/DC converters or first DC converters. The AC side energy routing conversion device and the DC side energy routing conversion device collect energy information of the energy devices and adjust energy of the energy devices on a basis of energy balance constraint conditions.

Abstract: A protection assembly of the electronic device is disposed along a side edge of a display screen assembly, and includes a decorative layer, a support, and a buffer layer. The support is located on a side of the display screen assembly, and is fastened to the side edge of the display screen assembly. The decorative layer is located on an outer side of the display screen assembly and the support. A first part of the decorative layer is bonded to a first surface of the support through a first adhesive layer, a second part of the decorative layer abuts against a screen surface through the buffer layer, and the first surface is a surface that is on the support and that is located on a side of the screen surface of the display screen assembly.

Abstract: A bispecific antibody directed against Claudin 18.2 and CD3, pharmaceutical compositions including the bispecific antibody, and a use thereof in the treatment of cancer are provided. The bispecific antibody includes an anti-CLDN18.2 binding domain and an anti-CD3 binding domain, the first binding domain being capable of binding to a CLDN18.2 protein, the second binding domain being capable of binding to CD3.

Abstract: A blockchain-based supervision system of hazardous chemical production includes: a collection layer, for collecting production data information, wherein a collection device in the collection layer sets a TEE to encrypt or hash the collected production data information; a data layer, for uplinking a hash certificate of the production data information through an alliance chain, wherein the collection layer communicates with the data layer; a blockchain, for deploying a file uplink contract and encrypting and storing a file on a privacy computing server after the file is connected to the trusted environment; and a privacy computing system, for forming a metadata market of the data from file description information, recording the metadata information of the collected data. A data user applies for the right of use to a production enterprise that produces the data, and after obtaining authorization, the data user performs various applications on the privacy computing system.

Abstract: Embodiments of the present disclosure disclose a method and an apparatus for restoring a NETCONF server to factory defaults, and relate to the field of configuration management technologies. A NETCONF server receives a command for restoring to factory defaults sent by a NETCONF client, where the command for restoring to factory defaults is a remote procedure call (RPC) command that is based on a Yang model of the NETCONF for restoring the NETCONF server to the factory defaults. The NETCONF server replaces data in the running configuration datastore with factory defaults of the NETCONF server according to the command for restoring to factory defaults.

Abstract: A blockchain-based supervision system of hazardous chemical production includes: a collection layer, for collecting production data information, wherein a collection device in the collection layer sets a TEE to encrypt or hash the collected production data information; a data layer, for uplinking a hash certificate of the production data information through an alliance chain, wherein the collection layer communicates with the data layer; a blockchain, for deploying a file uplink contract and encrypting and storing a file on a privacy computing server after the file is connected to the trusted environment; and a privacy computing system, for forming a metadata market of the data from file description information, recording the metadata information of the collected data. A data user applies for the right of use to a production enterprise that produces the data, and after obtaining authorization, the data user performs various applications on the privacy computing system.

Abstract: Disclosed are a method, device and system for tracking potential infected persons in a public place during an epidemic period. The method comprises: determining, according to associated information of a confirmed case, times of motions of the confirmed case in a public place and matching location information; searching for potential infected persons by means of video frame data provided by video monitoring devices in the public place based on an epidemic propagation mechanism; and tracking the potential infected persons based on multi-target tracking, and verifying the identity of the potential infected persons according to critical time nodes in the public place.

Abstract: Provided are a structured light module and an autonomous mobile device. A structured light module comprises a camera module and line laser emitters distributed on two sides of the camera module; the line laser emitters emit line laser outwards; and the camera module collects an environmental image detected by the line laser. By virtue of the advantage of high detection accuracy of the line laser, front environmental information may be detected more accurately. In addition, the line laser emitters are located on two sides of the camera module. This mode occupies a small size, may save more space, and is beneficial to expand an application scenario of a line laser sensor.

Abstract: Provided are a human GCGR antibody, a GLP-1 peptid and a mutant thereof, as well as a bispecific protein formed by fusion of the GCGR antibody and the GLP-1 peptide and a preparation method thereof, which can be used for weight loss and diabetes treatment.

Abstract: The present invention provides a fusion protein containing TGF-? receptor and pharmaceutical use thereof. Further, the present invention provides a bifunctional fusion protein comprising the PD-L1 antibody targeting portion and the TGF-?RII extracellular domain, and a pharmaceutical composition comprising the fusion protein containing TGF-? receptor, and the use thereof in the preparation of anti-cancer drug.

Abstract: The present disclosure provides an energy transmission method, an energy router and an operation control device thereof, and a storage medium, and relates to the field of energy network technology. The energy router of the present disclosure includes a plurality of ports configured to perform at least one of receiving or sending energy and PLC data, energy transmission switches, each of the energy transmission switches is configured to control open and closed states of one port of, and a routing processor configured to determine an energy transmission path according to the PLC data and stored routing information, determine a corresponding port associated with the energy transmission path, and turn on an energy transmission switch of the corresponding port, for the energy outputting from the corresponding port.

Abstract: An optical adjustment method and an optical adjustment device for a display panel, and a display device are provided. The optical adjustment method includes: displaying N groups of testing images sequentially on the display panel, each group of testing images including M images distributed at different display regions of the display panel, each image corresponding to one to-be-adjusted reference color, N being an integer greater than or equal to 1, M being an integer greater than or equal to 1; and when each group of testing images are displayed on the display panel, detecting, by an optical detection unit, optical parameters of the M images in the group of testing images simultaneously, and performing optical adjustment on the display panel in accordance with the optical parameters.

Abstract: Embodiments of the present disclosure disclose a method and an apparatus for restoring a NETCONF server to factory defaults, and relate to the field of configuration management technologies. A NETCONF server receives a command for restoring to factory defaults sent by a NETCONF client, where the command for restoring to factory defaults is a remote procedure call (RPC) command that is based on a Yang model of the NETCONF for restoring the NETCONF server to the factory defaults. The NETCONF server replaces data in the running configuration datastore with factory defaults of the NETCONF server according to the command for restoring to factory defaults.

Abstract: Embodiments of the present disclosure disclose a method and an apparatus for restoring a network device to factory defaults, and a network device, and relate to the field of configuration management technologies. A NETCONF server determines that the network device needs to be restored to the factory defaults; the NETCONF server replaces data in a startup configuration datastore and a running configuration datastore in the NETCONF server with factory defaults data in a factory defaults datastore, where the factory defaults datastore is dedicated to storing the factory defaults data of the network device. The NETCONF server delivers the data in the running configuration datastore after replacement to a plurality of service modules. Then, the plurality of service modules performs a validation operation based on the data delivered by the NETCONF server.