Abstract: A membrane for filtering one or more hydrophobic organic contaminants can include a porous nanostructure that includes one or more of a metal, a metal oxide, and a metal alloy nanostructure component functionalized with one or more amphiphilic ligands.

Abstract: The present application relates to antibodies specifically binding to immunoglobulin-like transcript 4 (ILT4), which is also known as LILRB2, LIR2, MIR10, and CD85d, and corresponding nucleic acids, host cells, compositions, and uses. In some embodiments, the antibodies bind specifically to human ILT4, but do not significantly bind to ILT2, ILT3, or ILT5, or to other members of the LILRA or LILRB families.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.

Abstract: A method for processing a time series includes dividing, with a processing device, the time series into a plurality of windows by time; extracting at least one group of similar subsequences from a current window among the plurality of windows; and updating a candidate list on the basis of comparison between similar subsequences in each group of the at least one group with k characteristic subsequences in the candidate list; wherein the k characteristic subsequences are k characteristic subsequences with a greatest number of occurrences in at least processed parts of the time series.

Abstract: Antibodies to human GITR are provided, as well as uses thereof, e.g., in treatment of proliferative and immune disorders.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.

Abstract: A method for processing a time series includes dividing, with a processing device, the time series into a plurality of windows by time; extracting at least one group of similar subsequences from a current window among the plurality of windows; and updating a candidate list on the basis of comparison between similar subsequences in each group of the at least one group with k characteristic subsequences in the candidate list; wherein the k characteristic subsequences are k characteristic subsequences with a greatest number of occurrences in at least processed parts of the time series.

Abstract: A plurality of messages comprising a stream of sensed data is received from an Internet of Things (IoT) device. A plurality of rules is identified. Responsive to a received message of the plurality of messages, the plurality of rules are distributed into a rule index tree based upon a cost model which minimizes a cost for analyzing the plurality of rules to determine whether or not each of the plurality of rules can be applied to the received message. The rule index tree is used to identify a set of rules of the plurality of rules that can be applied to the received message. The set of rules is applied to the received message to generate an outgoing message.

Abstract: A communication-type thermal conduction device includes a vapor chamber, at least one heat pipe, and at least one third capillary structure. The vapor chamber has a bottom board. A first capillary structure is disposed on an inner surface of the bottom board. A second capillary structure is disposed in the heat pipe. One end portion of the heat pipe is connected to the bottom board, and the end portion has an open portion in communication with the heat pipe and the vapor chamber. The second capillary structure has a connected portion exposed by means of the open portion. The third capillary structure is connected to the first capillary structure and the connected portion, so that the first and second capillary structures are in communication with each other. Accordingly, holistic thermal conduction can be achieved, and the vapor chamber incorporating the heat pipe can provide the desired heat dissipation effect.

Abstract: A three-dimensional heat transfer device includes a vapor chamber comprising a chamber body and a first capillary structure, and the first capillary structure being disposed in the chamber body; and a heat pipe comprising a pipe body and a second capillary structure, and the second capillary structure being disposed in the pipe body. The first capillary structure is connected to the second capillary structure by metallic bonding.

Abstract: The present disclosure relates to methods and systems for storing and querying data. According to the embodiments of the present invention, two-layer indexes are created for multi-dimension data, wherein the primary index is created based on two or more dimensions to retrieve respective data units of the data, while the secondary index is created based on specific dimensions to retrieve respective data blocks in the data unit. Correspondingly, when receiving a multi-dimension query request for data, the primary retrieval first determines a data unit including the target data based on a primary index, and then the secondary retrieval quickly locates a data block including the target data based on the secondary index. In this way, the multi-dimension retrieval can be efficiently performed. Moreover, by appropriately setting the size of a smallest data block, the I/O efficiency of data access will be significantly enhanced.

Abstract: The present disclosure relates to methods and systems for storing and querying data. According to the embodiments of the present invention, two-layer indexes are created for multi-dimension data, wherein the primary index is created based on two or more dimensions to retrieve respective data units of the data, while the secondary index is created based on specific dimensions to retrieve respective data blocks in the data unit. Correspondingly, when receiving a multi-dimension query request for data, the primary retrieval first determines a data unit including the target data based on a primary index, and then the secondary retrieval quickly locates a data block including the target data based on the secondary index. In this way, the multi-dimension retrieval can be efficiently performed. Moreover, by appropriately setting the size of a smallest data block, the I/O efficiency of data access will be significantly enhanced.

Abstract: A three-dimensional heat transfer device includes a vapor chamber comprising a chamber body and a first capillary structure, and the first capillary structure being disposed in the chamber body; and a heat pipe comprising a pipe body and a second capillary structure, and the second capillary structure being disposed in the pipe body. The first capillary structure is connected to the second capillary structure by metallic bonding.

Abstract: The system, method, and computer program product described herein provide unified real-time rule analytics to users through the use of an analytics logic editor that allows a user to construct an analytic logic rule unit that may be used on both edge and cloud devices. The user may select a data source, transform, rule condition, and action using an interface of the analytics logic editor to construct an analytics logic rule unit that may be deployed to both edge and cloud devices in real-time without the need to separately program each device. The analytics logic rule unit may be installed and executed by the edge and cloud device in real-time.

Abstract: A heat dissipation device, includes a vapor chamber including a heat conduction chamber and a first wick structure, the heat conduction chamber having a recessed portion, and the first wick structure disposed in the heat conduction chamber; and a heat pipe including a pipe body and a second wick structure disposed in the pipe body, the pipe body positioned in the recessed portion of the heat conduction chamber. The first wick structure and the second wick structure are metallically bonded.

Abstract: The system, method, and computer program product described herein provide unified real-time rule analytics to users through the use of an analytics logic editor that allows a user to construct an analytic logic rule unit that may be used on both edge and cloud devices. The user may select a data source, transform, rule condition, and action using an interface of the analytics logic editor to construct an analytics logic rule unit that may be deployed to both edge and cloud devices in real-time without the need to separately program each device. The analytics logic rule unit may be installed and executed by the edge and cloud device in real-time.

Abstract: A plurality of messages comprising a stream of sensed data is received from an Internet of Things (IoT) device. A plurality of rules is identified. Responsive to a received message of the plurality of messages, the plurality of rules are distributed into a rule index tree based upon a cost model which minimizes a cost for analyzing the plurality of rules to determine whether or not each of the plurality of rules can be applied to the received message. The rule index tree is used to identify a set of rules of the plurality of rules that can be applied to the received message. The set of rules is applied to the received message to generate an outgoing message.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.

Abstract: A communication-type thermal conduction device includes a vapor chamber, at least one heat pipe, and at least one third capillary structure. The vapor chamber has a bottom board, and a first capillary structure is disposed on an inner surface of the bottom board. A second capillary structure is disposed in the heat pipe. One end portion of the heat pipe is connected to the bottom board, and the end portion has an open portion in communication with the heat pipe and the vapor chamber. The second capillary structure has a connected portion exposed by means of the open portion. The third capillary structure is connected to the first capillary structure and the connected portion, so that the first and second capillary structures are in communication with each other. Accordingly, holistic thermal conduction can be achieved, and the vapor chamber incorporating the heat pipe can provide the desired heat dissipation effect.

Abstract: A computer-implemented method is provided that includes receiving a search request to perform a search in a time series database, where the time series database stores a plurality of sequences of measured values arranged in chronological order, extracting from the search request a condition for performing the search in the time series database, the condition including a target subsequence to be searched for within the plurality of sequences of measured values within the time series database, selecting a search algorithm to perform the search from a plurality of search algorithms registered to the time series database, based on one or more characteristics of the condition and historical statistic data of one or more historical searches conducted on the time series database, and obtaining a search result from the time series database, utilizing the search algorithm.