Abstract: The present disclosure provides a truncated Evans Blue modified fibroblast activation protein inhibitor compound. The compound is formed by connecting truncated Evans Blue, a fibroblast activation protein inhibitor and a nuclide chelating group by means of connecting groups L1, L2, L3, L4 and X. The compound has the following structure shown in Formula (I), where R1 is a fibroblast activation protein inhibitor; L1 is lysine, glutamic acid, or a derivative structure thereof; L2 is —(CH2)n—, n is an integer from 0 to 30, and each —CH2— may be individually substituted or unsubstituted with —O—, —NH—, —(CO)—, —NH(CO)—, or —(CO)—NH—; L3 is —(CH2)m—, m is an integer from 0 to 30, and each —CH2— may be individually substituted or unsubstituted with —O— or —(CO)—; L4 is —(CH2)p—, p is an integer from 0 to 30, and each —CH2— may be individually substituted or unsubstituted with —O—, —NH—, —(CO)—, —NH(CO)—, or —(CO)—NH—; X is selected from N, C, O, S, or and R2 is a nuclide chelating group.

Abstract: The present invention relates to a carbide tool cleaning and coating production line and a method, including a cleaning device including a support frame, a cleaning mechanism and a drying mechanism are sequentially disposed under the support frame connected to a moving mechanism, the moving mechanism is connected to a lifting mechanism being capable of being connected to a tool fixture bracket being configured to accommodate the tool fixture; a coating device including a coating chamber which a plane target mechanism and a turntable assembly disposed in, the turntable assembly is capable of being connected to a plurality of tool fixtures being capable of rotating around an axial line of the coating chamber under the driving of the turntable assembly and rotating around an axial line thereof at the same time; and, a manipulator being disposed between the cleaning device and the coating device.

Abstract: The present disclosure relates to the fields of nuclear medicine and molecular imaging, and specifically relates to a dual-targeting compound and a preparation method and application thereof. The dual-targeting compound has the following structure shown in Formula (I). The present disclosure also provides a dual-targeting compound capable of being labeled with a radionuclide, and the compound has the following structure shown in Formula (I-1) or Formula (I-2). The dual-targeting compound of the present disclosure has high affinity for an FAP target and an integrin ?v?3 target, can realize synergistic targeting of the FAP target and the integrin ?v?3 target in tumors, and has high uptake in tumors and long retention time in tumors.

Abstract: An extrusion type ice maker is provided which comprising a mounting frame with a compressor disposed at the bottom of the mounting frame and a condenser at the back surface; a cylinder is disposed above the compressor on the mounting frame, and a screw rod is disposed inside the cylinder; an evaporator is wound around the cylinder; a motor is disposed at the top of the mounting frame and an output shaft of the motor is in transmission connection with an upper end of the screw rod and the upper end of the screw rod is fixedly connected to the output shaft of the motor through a fixing pin; an outlet of the compressor is connected to an inlet of the condenser, and an outlet of the condenser is connected to an inlet of the evaporator; an outlet of the evaporator is connected to an inlet of the compressor.

Abstract: A present disclosure is a method of segmenting an abnormal robust for complex autonomous driving scenes and a system thereof, specifically relates to the technical field of an image segmenting system. The system includes: a segmentation module, configured to transmit an obtained input image to the segmentation network to obtain a segmentation prediction image, and then quantify the uncertainty of a segmentation prediction by means of calculating two different discrete metrics; a synthesis module, configured to match a generated data distribution with a data distribution of the input image by utilizing a conditional generative adversarial network; a difference module, configured to model and calculate the input image, an generated image, the semantic feature map and the uncertainty feature map based on an encoder, a fusion module and a decoder, to generate the segmentation prediction images for the abnormal objects; a model training module; and an integrated prediction module.

Abstract: The present disclosure provides a multi-factor quantitative analysis method for deformation of a neighborhood tunnel. The method includes the following steps: analyzing monitoring data generated at a tunnel site; simulating collapse occurring at a shallow buried section of a tunnel; determining the degree of influence of each factor on the tunnel and a stratum; and determining quantitative influence of each factor on tunnel deformation. The present disclosure can not only provide an accurate theoretical basis for the construction of the shallow buried section of the small-distance tunnel, but also guarantee safety and cost saving during tunnel construction.

Abstract: An automobile hub fixture includes a fixture body and a positioning apparatus. The fixture body includes a fixed platform and a plurality of clamping claws arranged at intervals in a circumferential direction of the fixed platform. The clamping claws are configured to clamp an outer rim of a hub. The plurality of clamping claws are connected to a driving member by using a linkage, and the driving member drives the clamping claws to radially move along the fixed platform. The positioning apparatus includes a movable platform slidably connected to the clamping claws. A positioning module configured to position an inner rim or the outer rim of the hub is mounted to the movable platform. The machining device includes a fixture, a machine tool, and a minimal quantity lubrication apparatus. The production line includes a machining device, a loading system, a loading and unloading manipulator, and a catching table.

Abstract: A method for presenting EPG user interface, including: in response to a first input command, displaying an EPG user interface including a first presentation page; and in response to a second input command, switching the EPG user interface from the first presentation page to a second presentation page, where the first presentation page includes a first set of channels and programs in a first time period corresponding to the first set of channels; and the second presentation page includes the first set of channels and programs in a second time period corresponding to the first set of channels.

Abstract: The present application provides a method and a device for charging a secondary battery, a computer storage medium and electronic equipment. The charging method includes steps of: sending first charge information to a charging source by a battery management system, the first charge information includes a first charge power; performing a constant-power charging on the secondary battery by the charging source according to the first charge power; sending a plurality of pulse discharge information to the charging source by the BMS when a battery status parameter reaches a first predetermined value, each pulse discharge information includes a discharge power and a discharge duration; and performing multiple constant-power pulse discharges on the secondary battery by the charging source according to the discharge power and the discharge duration in the plurality of pulse discharge information.

Abstract: A present disclosure is a method of segmenting an abnormal robust for complex autonomous driving scenes and a system thereof, specifically relates to the technical field of an image segmenting system. The system includes: a segmentation module, configured to transmit an obtained input image to the segmentation network to obtain a segmentation prediction image, and then quantify the uncertainty of a segmentation prediction by means of calculating two different discrete metrics; a synthesis module, configured to match a generated data distribution with a data distribution of the input image by utilizing a conditional generative adversarial network; a difference module, configured to model and calculate the input image, an generated image, the semantic feature map and the uncertainty feature map based on an encoder, a fusion module and a decoder, to generate the segmentation prediction images for the abnormal objects; a model training module; and an integrated prediction module.

Abstract: An in vitro release test (IVRT) method and system is provided for drug release testing. The IVRT method, referred to herein as adaptive perfusion, employ tangential-flow filtration (TFF), where released drug products that are smaller than a molecular weight cutoff (MWCO) of a membrane filter pass therethrough into the permeate. Unreleased drug products are retained by the pores of the filter and are recirculated to a retentate reservoir. Fresh media is provided to the retentate in order to maintain a constant total volume for the sample as well as to maintain sink conditions for the drug release. Drug concentration in the retentate and permeate are evaluated by in situ monitoring with one or more sensors and/or by periodic removal of aliquots from the respective reservoirs. In some embodiments, the membrane filter can be conditioned prior to use in order to improve the accuracy, precision, or both of the subsequent testing.

Abstract: The present disclosure provides Low Temperature NOx-Absorber (LT-NA) catalyst compositions, catalyst articles, and an emission treatment system for treating an exhaust gas, each including the LT-NA catalyst compositions. Further provided are methods for reducing a NOx level in an exhaust gas stream using the LT-NA catalyst articles. In particular, the LT-NA catalyst compositions include a first zeolite, a first palladium component, and a plurality of platinum nanoparticles. The LT-NA catalyst compositions exhibit enhanced regeneration efficiency with respect to NOx adsorption capacity, even after hydrothermal aging.

Abstract: A steel material is disclosed. The steel material includes components in the following mass percentages: 14% to 20% of nickel, 7.5% to 11% of cobalt, 4% to 7% of molybdenum, to 0.5% of rhenium and/or a rare earth element, less than or equal to 0.2% of manganese, less than or equal to 0.2% of silicon, less than or equal to 0.1% of carbon, less than or equal to of oxygen, iron, and inevitable impurities. The steel mechanical part is made of the steel material. The preparation method includes: mixing alloy powder and a binder to prepare feed particles; performing injection molding on the feed particles to obtain an injection green billet of the steel mechanical part; performing debinding and sintering on the injection green billet in sequence to obtain a sintered blank; and performing heat treatment on the sintered blank to obtain the steel mechanical part.

Abstract: A steel, a steel mechanical part, an electronic device, and a preparation method for a steel mechanical part are provided. The steel includes components of the following mass percentages: chromium: 7% to 11%, nickel: 2% to 7.5%, cobalt: 6% to 15%, molybdenum: 4% to 7%, oxygen: a trace to 0.4%, carbon: a trace to 0.35%, and iron: 50% to 80%. The steel provided in this application has relatively high mechanical strength and is not easily deformed, and therefore a risk of fracture caused when an electronic device using the steel falls off from a height is reduced.

Abstract: The present invention discloses a fully-assembled staircase system and an assembly method. The fully-assembled staircase system includes a stair slab, stair steps, stair stringers, landing slabs, steel connectors, and a stair handrail, where a main body of the stair slab is an inclined flat plate structure, lap joints are disposed at an upper end and a lower end of the stair slab LTB, an outer edge of an upper surface of the lap joint is provided with first grooves, one side of the landing slab PB is provided with second grooves, the stair stringer is an inverted T-shaped structure, a top surface of a web of the stair stringer is provided with third grooves, two flanges of the stair stringer are respectively fixedly lapped with the stair slab and the landing slab, the first groove, the third groove, and the second groove after the lapping jointly form a steel-connector groove.

Abstract: Provided are a dihydronaphthyridinone compound as shown in formula (I), which compound has a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof. In addition, provided are a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating RIPK1-related diseases or conditions.

Abstract: This invention relates to antimicrobial gallium compounds, and to monomers containing gallium complex moieties that can be used in oral care products and dental materials, and which can reduce or eliminate dental caries and bacterial or fungal infections associated with medical and dental devices.

Abstract: Compounds and methods for treatment of cancers such as multiple myeloma by inhibition of germinal center kinase.

Abstract: The present disclosure provides Low Temperature NOx-Absorber (LT-NA) catalyst compositions, catalyst articles, and an emission treatment system for treating an exhaust gas, each including the LT-NA catalyst compositions. Further provided are methods for reducing a NOx level in an exhaust gas stream using the LT-NA catalyst articles. In particular, the LT-NA catalyst compositions include a first zeolite, a first palladium component, and a plurality of platinum nanoparticles. The LT-NA catalyst compositions exhibit enhanced regeneration efficiency with respect to NOx adsorption capacity, even after hydrothermal aging.

Abstract: The present disclosure provides a robot, a control method for robot and a storage medium, the robot includes a memory, a processor and a computer program stored on the memory and running on the processor, and when the processor executes the computer program to obtain, material information of a working surface and determine, a target running speed of the robot according to the material information, and control the robot to run at the target running speed. The robot provided by the present disclosure controls the operating speed according to the material information of the working surface, and the robot can clean at different speeds for different materials when cleaning. If the detected material of the working surface is a material that is not easy to clean, you can set the speed to a low speed mode accordingly.