Abstract: The present invention discloses a nucleic acid detection kit and a detection method based on photo-controlled CRISPR-Cas, wherein the kit comprises silent guide RNA and Cas protein; the silent guide RNA is formed by annealing hybridization of silent nucleotide and guide RNA; the guide RNA, designed according to a target nucleic acid sequence, includes two regions, i.e. a repetitive region and a spacer region; the silent nucleotide is completely complementarily paired with a the of the guide RNA, or is completely paired with a the of the guide RNA; the bases of the silent nucleotide are linked by PC linker; and the Cas protein is Cas12 protein or Cas13 protein. Although this method separates the nucleic acid amplification from the CRISPR-Cas detection in time, it can allow them to be completed in the same closed reaction tube, thereby avoiding the transfer process of uncapped reagent, ensuring that the detection is not affected by aerosol pollution while ensuring high detection sensitivity.

Abstract: Techniques for code modification for detecting abnormal activity are described. Web code is obtained. Modified web code is generated by changing a particular programmatic element to a modified programmatic element throughout the web code. Instrumentation code is generated configured to monitor and report on one or more interactions with versions of the particular programmatic element. The instrumentation code is caused to be provided in association with the modified web code to the first client device in response to the first request from the first client device. Report data generated by the instrumentation code is received. The report data describes abnormal activity at the first client device, the abnormal activity comprising an interaction with a version of the particular programmatic element that does not exist in the modified web code. Based on the report, it is determined that the first client device is likely controlled by malware.

Abstract: The invention provides method, device, and system to commission medical devices using different wireless communication protocol or from different manufacturers to a network by introducing a pairing device and a guiding device. The commissioning process includes two steps, e.g., a pairing the medical device to the pairing device and a pairing between the pairing device and server of the network. By configuring a pairing device dynamically with the aid of a guiding device, the pairing device can receive broadcast messages from medical devices using different communication protocols and send the same to a remote server having a specific network address. Further, the guiding device is introduced not only to assist in the configuration of the pairing device, but also provide an opportunity to the pairing device to obtain a real-time feedback from the remote server through the guiding device during installation.

Abstract: Systems and methods for generating an entity classification model using text classification of raw text information of entities are described. Generating the classification model includes obtaining raw text information associated with a plurality of entities, converting the raw text information for each entity of the plurality of entities into one or more character strings, generating a numerical vector for each entity of the plurality of entities based on the one or more character strings for each entity, and selecting, based on the numerical vectors for each entity of the plurality of entities, one or more entity properties to be used for entity classification. A classification of a first entity coupled to a network is performed based on the one or more selected entity properties.

Abstract: Techniques for code modification for detecting abnormal activity are described. Web code is obtained. Modified web code is generated by changing a particular programmatic element to a modified programmatic element throughout the web code. Instrumentation code is generated configured to monitor and report on one or more interactions with versions of the particular programmatic element. The instrumentation code is caused to be provided in association with the modified web code to the first client device in response to the first request from the first client device. Report data generated by the instrumentation code is received. The report data describes abnormal activity at the first client device, the abnormal activity comprising an interaction with a version of the particular programmatic element that does not exist in the modified web code. Based on the report, it is determined that the first client device is likely controlled by malware.

Abstract: The present disclosure relates to the field of ultrasonic detection, in particular to a craniocerebral ultrasonic standard plane imaging and automatic detection and display method for abnormal regions. The following technical solution is adopted: contour detection is performed on the scanned ultrasound images the skull to construct a skull surface model, and the standard planes in ultrasound images are identified and extracted according to the skull surface model. The symmetry of the standard planes in ultrasound images is used to compare the similarity, so as to obtain the abnormal regions for segmentation and display. The advantages of the present disclosure are as follows: the skull surface model is constructed by detecting the cranial edge, and the coordinate system is established based on this model, thereby the standard planes in ultrasound images can be quickly identified from the scanned ultrasound images.

Abstract: Techniques for code modification for detecting abnormal activity are described. Web code is obtained. Modified web code is generated by changing a particular programmatic element to a modified programmatic element throughout the web code. Instrumentation code is generated configured to monitor and report on one or more interactions with versions of the particular programmatic element. The instrumentation code is caused to be provided in association with the modified web code to the first client device in response to the first request from the first client device. Report data generated by the instrumentation code is received. The report data describes abnormal activity at the first client device, the abnormal activity comprising an interaction with a version of the particular programmatic element that does not exist in the modified web code. Based on the report, it is determined that the first client device is likely controlled by malware.

Abstract: The present disclosure relates to methods and tools for enhancing cognition in an individual. The methods involve presenting to the individual multiple sets of stimuli. Each set of the multiple set contains two or more stimuli and at least one set of the multiple sets contains a target stimulus. The method then receives an input from the individual, and informs the individual as to whether the input is a correct response. The methods encompass iterations of stimuli presentation, receiving of the input, and lastly, generation of feedback to the individual until the individual learns and retains what the target stimulus is.

Abstract: A preparation method of adiposomes, and use thereof. Provided is a method for preparing adiposomes consisting of neutral lipids and a monolayer phospholipid membrane, comprising a1) vortexing phospholipid and neutral lipids in a buffer, centrifuging the resulting mixture, and collecting an upper liquid phase; a2) purifying the upper liquid phase twice or more by uniformly mixing the upper liquid phase with the buffer, layering the mixture, and collecting an upper liquid phase; and a3) uniformly mixing the upper liquid phase obtained in step a2) with the buffer, layering the mixture, and collecting a lower liquid phase in containing adiposomes. For the adiposomes prepared by the method, one or more resident proteins and/or functional proteins can be recruited to obtain artificial lipid droplets, and one or more apolipoproteins can be recruited to obtain artificial lipoproteins; and they all play important roles in preparing drugs and/or drug carriers.

Abstract: The present invention provides a hemostatic powder. The hemostatic powder is mainly present in the form of a columnar particle, wherein the ratio of axial length to diameter of the columnar particle is less than 5; the hemostatic powder includes a polymer represented by the following structural formula: wherein the R is at least one selected from the group consisting of —NH2, —OCH2CH2OH, —OCH2CH2CH2OH, —OH, —ONa, —OK and —OCa; m, n and p respectively represent number percentages of corresponding repeating units in polymer molecules, and satisfy the following equations: m+n+p=1, p/(m+n+p)=0.05˜0.

Abstract: The present disclosure relates to methods and tools for enhancing cognition in an individual. The methods involve presenting to the individual multiple sets of stimuli. Each set of the multiple set contains two or more stimuli and at least one set of the multiple sets contains a target stimulus. The method then receives an input from the individual, and informs the individual as to whether the input is a correct response. The methods encompass iterations of stimuli presentation, receiving of the input, and lastly, generation of feedback to the individual until the individual learns and retains what the target stimulus is.

Abstract: The present invention provides a hemostatic powder. The hemostatic powder is mainly present in the form of a columnar particle, wherein the ratio of axial length to diameter of the columnar particle is less than 5; the hemostatic powder includes a polymer represented by the following structural formula: wherein the R is at least one selected from the group consisting of —NH2, —OCH2CH2OH, —OCH2CH2CH2OH, —OH, —ONa, —OK and —OCa; m, n and p respectively represent number percentages of corresponding repeating units in polymer molecules, and satisfy the following equations: m+n+p=1, p/(m+n+p)=0.05˜0.

Abstract: In various embodiments, an air quality-monitoring system (100) may include at least one sensor (106) configured to detect operation of a mechanism (110) within or at a boundary of an indoor environment. The mechanism may be external to an air purifier (102) associated with the indoor environment. The system may include a persistent memory (124) for storing data about the indoor environment observed by the at least one sensor (106).

Abstract: Techniques for code modification for detecting abnormal activity are described. Web code is obtained. Modified web code is generated by changing a particular programmatic element to a modified programmatic element throughout the web code. Instrumentation code is generated configured to monitor and report on one or more interactions with versions of the particular programmatic element. The instrumentation code is caused to be provided in association with the modified web code to the first client device in response to the first request from the first client device. Report data generated by the instrumentation code is received. The report data describes abnormal activity at the first client device, the abnormal activity comprising an interaction with a version of the particular programmatic element that does not exist in the modified web code. Based on the report, it is determined that the first client device is likely controlled by malware.

Abstract: Provided are methods and tools for enhancing cognition in an individual. The methods involve presenting to the individual multiple sets of stimuli. Each set of the multiple set contains two or more stimuli and at least one set of the multiple sets contains a target stimulus. The method then receives an input from the individual, and informs the individual as to whether the input is a correct response. The methods encompass iterations of stimuli presentation, receiving of the input, and lastly, generation of feedback to the individual until the individual learns and retains what the target stimulus is.

Abstract: In an embodiment, a method comprises intercepting a first set of instructions from a server computer that define one or more objects and one or more original operations that are based, at least in part, on the one or more objects; modifying the first set of instructions by adding one or more supervisor operations that are based, at least in part, on the one or more objects; transforming the one or more original operations to produce one or more transformed operations that are based, at least in part, on the one or more supervisor operations; rendering a second set of instructions which define the one or more supervisor operations and the one or more transformed operations; sending the second set of instructions to a remote client computer.

Abstract: Techniques for code modification for automation detection are described. Web code is obtained corresponding to content to be served to a first client device in response to a first request from the first client device. Instances of a particular programmatic element in the web code are identified. In response to the first request, modified web code is generated from the web code by consistently changing the particular programmatic element to a modified programmatic element throughout the web code. The modified web code is caused to be provided to the first client device in response to the first request from the first client device. A communication is received from the first client device that is made in response to the modified web code. The communication includes an attempt to interact with the particular programmatic element that exists in the web code but not in the modified web code.

Abstract: Systems and methods for detecting a live human face in an image are disclosed. The methods and systems are capable of receiving multispectral image data that includes a human face. The multispectral image data can comprise visible light image data and near-infrared (NIR) image data. The multispectral image data can be processed to detect the human face. The detected human face in the visible light image data can be associated with the detected human face in the NIR image data to determine whether the detected human face is a live human face.

Abstract: A preparation method of adiposomes, and use thereof. Provided is a method for preparing adiposomes consisting of neutral lipids and a monolayer phospholipid membrane, comprising a1) vortexing phospholipid and neutral lipids in a buffer, centrifuging the resulting mixture, and collecting an upper liquid phase; a2) purifying the upper liquid phase twice or more by uniformly mixing the upper liquid phase with the buffer, layering the mixture, and collecting an upper liquid phase; and a3) uniformly mixing the upper liquid phase obtained in step a2) with the buffer, layering the mixture, and collecting a lower liquid phase in containing adiposomes. For the adiposomes prepared by the method, one or more resident proteins and/or functional proteins can be recruited to obtain artificial lipid droplets, and one or more apolipoproteins can be recruited to obtain artificial lipoproteins; and they all play important roles in preparing drugs and/or drug carriers.

Abstract: Techniques are provided for using instrumentation code to detect bots or malware. Data corresponding to requests from a plurality of client devices for a web resource comprising web code is obtained. The web resource is hosted by a first web server system. For a first client device of the plurality of client devices, instrumentation code is served. The instrumentation code is configured to execute on the first client device to monitor execution of the web code of the web resource at the first client device. One or more responses generated by the instrumentation code at the first client device are received from the first client device. The one or more responses are based one or more interactions with the web code at the first client device.