Abstract: Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking and methods of making and using thereof.

Abstract: A mounting apparatus for mounting a data storage device includes a bracket and a blocking member. The bracket includes a front panel and two sidewalls extending from opposite ends of the front panel. The blocking member is positioned between the sidewalls of the bracket opposite to the front panel and pivotably attached to the sidewalls of the bracket.

Abstract: A mounting mechanism for attaching a data storage device to a chassis includes a housing, first and second driving members, a latching member, first, second, and third elastic members. The housing defines first, second and third sliding paths therein. The first and third sliding paths extend along a first direction of the housing for receiving the first driving member and the latching member. The second sliding path extends along a second direction of the housing substantially perpendicular to the first direction for receiving the second driving member. The first driving member forms an inclined guiding surface at an end thereof outside the housing. When the guiding surface is pressed down, the driving member moves inward, driving the second driving to move and disengage from the latching member, and the latching member moves along the first direction by an elastic force of the third elastic member.

Abstract: A caster for being mounted to a bottom of a device includes a support, a connecting member, and a wheel mounted to the connecting member. The support defines a receiving space. The connecting member is threadedly connected to the support, and comprises a bracket accommodated in the receiving space. The wheel is rotatably mounted to the bracket. The support and the connecting member are operable to rotate relative to each other, with the wheel moving to expose out of or retract inside the receiving space.

Abstract: A mounting apparatus for attaching a data storage device to a chassis includes a latching member, first and second elastic members and a button. The latching member defines a through hole therein and forms a latching pin at a first end thereof. The button includes an abutting portion and a pressing portion extending up from the abutting portion. When the mounting apparatus is mounted to the chassis, the button is placed on a bottom side of the latching member, the latching member is movably mounted to the chassis, the first elastic member is compressed between the second end of the latching member and a baffle formed on the chassis, the second elastic member is compressed between the button and the chassis, the pressing portion of the button extends through the through hole and extending out of a top surface of the latching member.

Abstract: Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking by introduction of at least one hydrazide-reactive group and/or aminooxy-reactive group, and methods of making and using thereof for scar-free wound healing, for delivering bioactive agents or living cells, for preventing adhesion after a surgical procedure or for bone and cartilage repair. The macromolecule can be an oligonucleotide, a necleic acid, a polypeptide, a lipid, a glycoprotein, a glycolipid, a polysaccharide, a protein or a synthetic polymer, preferably a glycosaminoglycan like hyaluronan.

Abstract: A mounting mechanism for attaching a data storage device to a chassis includes a housing, first and second driving members, a latching member, first, second, and third elastic members. The housing defines first, second and third sliding paths therein. The first and third sliding paths extend along a first direction of the housing for receiving the first driving member and the latching member. The second sliding path extends along a second direction of the housing substantially perpendicular to the first direction for receiving the second driving member. The first driving member forms an inclined guiding surface at an end thereof outside the housing. When the guiding surface is pressed down, the driving member moves inward, driving the second driving to move and disengage from the latching member, and the latching member moves along the first direction by an elastic force of the third elastic member.

Abstract: A mounting apparatus for attaching a data storage device to a chassis includes a latching member, first and second elastic members and a button. The latching member defines a through hole therein and forms a latching pin at a first end thereof. The button includes an abutting portion and a pressing portion extending up from the abutting portion. When the mounting apparatus is mounted to the chassis, the button is placed on a bottom side of the latching member, the latching member is movably mounted to the chassis, the first elastic member is compressed between the second end of the latching member and a baffle formed on the chassis, the second elastic member is compressed between the button and the chassis, the pressing portion of the button extends through the through hole and extending out of a top surface of the latching member.

Abstract: Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) die oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one thiol compound with at least one thiol-reactive compound.

Abstract: The invention relates to methods of modulating immune responses in a subject, such as by administering to the subject agents which modulate tim-1, tim-2 or tim-4 activity, or which modulate the physical interaction between tim-1 and tim-4 or between tim-2 and a tim-2 ligand. Immune responses include, but are not limited to, autoimmune disorders, transplantation tolerance, and Th1 and Th2-mediated responses and disorders. The invention also relates to novel assays for identifying agents which modulate the physical interaction between tim-1 and tim-4. In addition, the invention relates to novel soluble tim-4 polypeptides and to nucleic acids which encode them.

Abstract: A fixing apparatus includes a frame having two opposite fixing walls to fix a first storage device. The fixing apparatus further includes a supporting arm pivotally connected to the frame. The supporting arm includes a fixing plate rotatable between a first position where a second storage device is capable of being sandwiched between the fixing plate and the second fixing wall of the frame, and a second position where the first storage device is capable of being sandwiched between the fixing walls of the frame.

Abstract: The invention provides isolated regulatory T cells and methods of obtaining regulatory T cells. The invention also provides methods for inhibiting an antigen-specific immune response (e.g., graft rejection, an autoimmune disorder, graft versus host disease, a response to a tumor cell, a response to an infection, and a response to an allergen) in a subject requiring administering an isolated regulatory T cell to the subject. The invention further provides methods for treating or modulating an antigen-specific immune response in a subject requiring administering a regulatory T cell to the subject.

Abstract: The invention relates to methods of modulating immune responses in a subject, such as by administering to the subject agents which modulate tim-1, tim-2 or tim-4 activity, or which modulate the physical interaction between tim-1 and tim-4 or between tim-2 and a tim-2 ligand. Immune responses include, but are not limited to, autoimmune disorders, transplantation tolerance, and Th1 and Th2-mediated responses and disorders. The invention also relates to novel assays for identifying agents which modulate the physical interaction between tim-1 and tim-4. In addition, the invention relates to novel soluble tim-4 polypeptides and to nucleic acids which encode them.

Abstract: A mounting apparatus for a data storage device that includes a tab includes a bracket, a locking member, and an operating assembly. The bracket includes a bezel defining an opening and a first cutout corresponding to the tab. The locking member, movable on the bezel, defines a second cutout corresponding to the first cutout. The operating assembly is assembled in the bezel and slides the locking member on the bezel to align or misalign the second cutout with the first cutout.

Abstract: A fixing apparatus for fixing a data storage device with a plurality of mounting holes defined in sidewalls thereof includes a first bracket, a second bracket, and a latch member. The first bracket includes a side sheet and a base sheet perpendicularly connected thereto. The second bracket includes a side sheet, and a base sheet perpendicularly connected thereto. The base sheet of the second bracket is pivotally attached to the base sheet of the first bracket. The latch member is slidably attached to the base sheet of the first bracket and engages with the base sheet of the second bracket. A plurality of fixing pins extends from the side sheets of the first bracket and the second bracket, corresponding to the mounting holes of the data storage device.

Abstract: A fixing apparatus for fixing a data storage device with a plurality of mounting holes defined in sidewalls thereof includes a first bracket, a second bracket, and a latch member. The first bracket includes a side sheet and a base sheet perpendicularly connected thereto. The second bracket includes a side sheet, and a base sheet perpendicularly connected thereto. The base sheet of the second bracket is pivotally attached to the base sheet of the first bracket. The latch member is slidably attached to the base sheet of the first bracket and engages with the base sheet of the second bracket. A plurality of fixing pins extends from the side sheets of the first bracket and the second bracket, corresponding to the mounting holes of the data storage device.

Abstract: A mounting apparatus for a data storage device that includes a tab includes a bracket, a locking member, and an operating assembly. The bracket includes a bezel defining an opening and a first cutout corresponding to the tab. The locking member, movable on the bezel, defines a second cutout corresponding to the first cutout. The operating assembly is assembled in the bezel and slides the locking member on the bezel to align or misalign the second cutout with the first cutout.

Abstract: The present invention is based, in part, on expression studies of IL-2 and IL-15 receptor subunits by cycling T cells in vivo. In one embodiment, the invention generally features novel combinations of IL-2 and IL-15 antagonists and methods of suppressing the immune response by administering these antagonists. In each case, suppression is achieved by administration of a first agent that targets an IL-15 molecule or an IL-15 receptor (IL-15R) and a second agent that targets an IL-2 molecule or an IL-2 receptor (IL-2R). More generally, the invention features novel combinations of agents that, when administered to a patient (or to a transplant ex vivo), reduce the number of antigen-reactive T cells. For example, the invention features compositions (e.g., pharamaceutically acceptable compositions) that include two or more agents, each of which promote T cell death. Alternatively, the composition can contain at least one agent that promotes T cell death and at least one agent that inhibits T cell proliferation.

Abstract: Described herein are composites that inhibit or reduce adhesion between two or more tissues. Also described herein are methods of using the composites.

Abstract: Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) die oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one thiol compound with at least one thiol-reactive compound.