Patents by Inventor XIAO ZHENG

XIAO ZHENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CROSSLINKED COMPOUNDS AND METHODS OF MAKING AND USING THEREOF
    Publication number: 20090105193
    Abstract: Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) the oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one thiol compound with at least one thiol-reactive compound.
    Type: Application
    Filed: September 19, 2008
    Publication date: April 23, 2009
    Applicant: University of Utah Research Foundation
    Inventors: Glenn D. Prestwich, Xiao Zheng Shu, Yi Luo, Kelly R. Kirker, Yanchun Liu
  • FASTENER ASSEMBLY
    Publication number: 20090028664
    Abstract: A fastener assembly includes a drive shaft, a threaded shaft, and a joint portion. The drive shaft is used for being operated to rotate around an axis thereof. The threaded shaft has a thread thereon, and is used for being screwed into an object. The joint portion is used for connecting the drive shaft with the threaded shaft. The joint portion is able to transfer the rotation of the drive shaft to the threaded shaft, and allow the rotations of the drive shaft and the threaded shaft about different axes.
    Type: Application
    Filed: December 24, 2007
    Publication date: January 29, 2009
    Applicants: HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: WEN-TANG PENG, GUANG-YI ZHANG, XIAO-ZHENG LI
  • Transplant tolerance by costimulation blockade and T-cell activation-induced apoptosis
    Publication number: 20080089894
    Abstract: The invention relates to methods of inducing tolerance and preventing transplant rejection by blocking costimulatory signals and using immunosuppressive agents, preferably rapamycin, to prevent late rejection episodes, yet not block tolerance inducing T-cell specific depletion; compositions and kits for use in such methods are also provided herein.
    Type: Application
    Filed: December 5, 2007
    Publication date: April 17, 2008
    Inventors: Terry Strom, Xin Xiao Zheng
  • Compositions and methods for achieving immune suppression
    Patent number: 7347995
    Abstract: Disclosed herein are therapeutic compositions containing agents that modulate the immune response in a patient.
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: March 25, 2008
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Terry B. Strom, Wlodzimierz Maslinski, Xin Xiao Zheng, Yon Su Kim, Sylvie Ferrari-Lacraz
  • Modified Macromolescules and Associated Methods of Synthesis and Use
    Publication number: 20080025950
    Abstract: Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking by introduction of at least one hydrazide-reactive group and/or aminooxy-reactive group, and methods of making and using thereof for scar-free wound healing, for delivering bioactive agents or living cells, for preventing adhesion after a surgical procedure or for bone and cartilage repair. The macromolecule can be an oligonucleotide, a necleic acid, a polypeptide, a lipid, a glycoprotein, a glycolipid, a polysaccharide, a protein or a synthetic polymer, preferably a glycosaminoglycan like hyaluronan.
    Type: Application
    Filed: December 6, 2004
    Publication date: January 31, 2008
    Inventors: Glenn D. Prestwich, Xiao Zheng Shu, Yanchun Liu
  • Chimeric IL-10
    Patent number: 7018626
    Abstract: Disclosed are chimeric proteins having a cytokine fused to an enzymatically inactive polypeptide which increases the circulating half-life of the cytokine. The chimeric proteins are useful for treating, inhibiting, or preventing a variety of conditions, including septic shock, granulomatous disorders, Type I diabetes, and various cancers (e.g., multiple myeloma) in a patient.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: March 28, 2006
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Terry B. Strom, Xin Xiao Zheng, Alan Steele
  • Compositions and methods for achieving immune suppression
    Publication number: 20040219148
    Abstract: Disclosed herein are therapeutic compositions containing agents that modulate the immune response in a patient.
    Type: Application
    Filed: May 25, 2004
    Publication date: November 4, 2004
    Applicant: Beth Israel Deaconess Medical Center, Inc., a Massachusetts corporation
    Inventors: Terry B. Strom, Wlodzimierz Maslinski, Xin Xiao Zheng, Yon Su Kim, Sylvie Ferrari-Lacraz
  • Compositions and methods for achieving immune suppression
    Patent number: 6797263
    Abstract: Disclosed herein are therapeutic compositions containing agents that modulate the immune response in a patient.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: September 28, 2004
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Terry B. Strom, Wlodzimierz Maslinski, Xin Xiao Zheng, Yon Su Kim, Sylvie Ferrari-Lacraz
  • Treatment of diabetes
    Patent number: 6770272
    Abstract: Disclosed are chimeric proteins having IL-10 fused to an enzymatically inactive polypeptide which increases the circulating half-life of IL-10. The chimeric polypeptides are useful for treating or preventing septic shock, inhibiting the development of Type I diabetes, and treating multiple myeloma in a patient.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: August 3, 2004
    Assignee: Beth Israel Hospital Association
    Inventors: Terry B. Strom, Xin Xiao Zheng, Alan Steele
  • Chimeric cytokines and uses thereof
    Publication number: 20030026778
    Abstract: Disclosed are chimeric proteins having a cytokine fused to an enzymatically inactive polypeptide which increases the circulating half-life of the cytokine. The chimeric proteins are useful for treating, inhibiting, or preventing a variety of conditions, including septic shock, granulomatous disorders, Type I diabetes, and various cancers (e.g., multiple myeloma) in a patient.
    Type: Application
    Filed: May 14, 2002
    Publication date: February 6, 2003
    Applicant: Beth Israel Hospital Association, a Massachusetts corporation
    Inventors: Terry B. Strom, Xin Xiao Zheng, Alan Steele
  • Chimeric IL-10 proteins and uses thereof
    Publication number: 20020173628
    Abstract: Disclosed are chimeric proteins having IL-10 fused to an enzymatically inactive polypeptide which increases the circulating half-life of IL-10. The chimeric polypeptides are useful for treating or preventing septic shock, inhibiting the development of Type I diabetes, and treating multiple myeloma in a patient.
    Type: Application
    Filed: May 14, 2002
    Publication date: November 21, 2002
    Applicant: Beth Israel Hospital Association
    Inventors: Terry B. Strom, Xin Xiao Zheng, Alan Steele
  • Compositions and methods for achieving immune suppression
    Publication number: 20020128436
    Abstract: Disclosed herein are therapeutic compositions containing agents that modulate the immune response in a patient.
    Type: Application
    Filed: May 14, 2001
    Publication date: September 12, 2002
    Inventors: Terry B. Strom, Wlodzimierz Maslinski, Xin Xiao Zheng, Yon Su Kim, Sylvie Ferrari Lacraz
  • Chimeric IL-10 proteins and uses thereof
    Patent number: 6410008
    Abstract: Disclosed are chimeric proteins having IL-10 fused to an enzymatically inactive polypeptide which increases the circulating half-life of IL-10. The chimeric polypeptides are useful for treating or preventing septic shock, inhibiting the development of Type I diabetes, and treating multiple myeloma in a patient.
    Type: Grant
    Filed: December 12, 1994
    Date of Patent: June 25, 2002
    Assignee: Beth Israel Hospital Association
    Inventors: Terry B. Strom, Xin Xiao Zheng, Alan Steele
  • Treatment regimes featuring an IL-10-containing chimeric polypeptide
    Patent number: 6403077
    Abstract: Disclosed are chimeric proteins having a cytokine fused to an enzymatically inactive polypeptide which increases the circulating half-life of the cytokine. The chimeric proteins are useful for treating, inhibiting, or preventing a variety of conditions, including septic shock, granulomatous disorders, Type I diabetes, and various cancers (e.g., multiple myeloma) in a patient.
    Type: Grant
    Filed: November 6, 1997
    Date of Patent: June 11, 2002
    Assignee: Beth Israel Hospital Association
    Inventors: Terry B. Strom, Xin Xiao Zheng, Alan Steele