Abstract: Disclosed are a compound of formula (I), a stereoisomer, solvate, prodrug, metabolite, pharmaceutically acceptable salt, or eutectic thereof, or a pharmaceutical composition comprising same, and an application thereof as an ATX inhibitor in preparation of a drug for treating a related disease. Groups in formula (I) are as defined in the description.

Abstract: A safety control mechanism for performing safety control on a battery includes a voltage generation module and a safety member. The voltage generation module is configured to establish a voltage difference between the safety member and the battery. When the battery is abnormal, the voltage difference causes the safety member to perform safety control.

Abstract: A thermal runaway trigger method relates to the technical field of batteries. The thermal runaway trigger method includes: providing a battery cell and a heating member arranged in the battery cell; and heating the inside of the battery cell by the heating member, so as to cause a thermal runaway of the battery cell. The heating member is arranged inside the battery cell, and the heating member heats the inside of the battery cell to cause the thermal runaway of the battery cell, so that the inside of the battery cell can be heated to cause the thermal runaway of the battery cell in a relatively short time. Due to the reduced internal space of the battery cell, the range of diffusion of the heating member inside the battery cell is small, and the heat loss of the heating member is relatively small.

Abstract: A computer-implemented method, system and computer program product for improving performance of a distributed database. A query is received to store version data in the distributed database. Upon receiving the query to store the version data, the version data is stored in a row of a data page of a main table of a heap organized table/index organized table of the distributed database, where the row of the data page of the main table of the heap organized table/index organized table of the distributed database contains a pointer pointing to a later/previous version of the version data if the later/previous version of the version data is stored in the data page thereby chaining version data bi-directionally.

Abstract: A method includes receiving, by a computing device, a Structured Query Language (SQL) query from a user; generating, by the computing device, execution structures from the SQL query; generating, by the computing device, test results by running the SQL query with the execution structures; building, by the computing device, logs which record information of the running of the SQL query; generating, by the computing device, a candidate execution structure using the information from the logs; normalizing, by the computing device, the SQL query using the candidate execution structure; running, by the computing device, the normalized SQL query in a database; and comparing, by the computing device, results of the normalized SQL query to the test results.

Abstract: An integrated circuit-based nano-relay, comprising: an integrated circuit system of the nano-relay constructed according to an integrated circuit module built from a combinational logic circuit. An integrated power data processing algorithm is called by means of the integrated circuit module to perform signal processing on an input power signal, and power service data is output, that is, an integrated circuit is mainly constructed by means of the combinational logic circuit, the protection logic of the nano-relay is achieved by means of a hardware circuit module, and a response speed of the relay is improved.

Abstract: Provided is the following compound or a pharmaceutically acceptable salt, ester, optical isomer, stereoisomer, polymorphic substance, solvate, N-oxide, isotope-labeled compound, metabolite, chelate, coordination complex, inclusion compound or prodrug thereof, and a pharmaceutical composition comprising the compound. Also provided is an application of the compound in preparing a drug for a disease associated with SHP2 phosphatase. Also provided is a method for treating a disease associated with SHP2 phosphatase.

Abstract: A computer-implemented method to estimate computing cost of database queries. The method includes receiving a query. The method also includes generating one or more access plans for the query. The method further includes dynamically generating a learning model based on each of the generated access plans. The method includes estimating, by the learning model and for each of the one or more access plans, a predicted cost to execute the query. The method includes selecting, based on the predicted cost, a first access path associated with a lowest cost of the predicted costs and executing the query according the selected access path.

Abstract: A light-emitting device includes at least one light-emitting unit including a luminescent layer, an electron functional layer and a hole functional layer; a material of the luminescent layer includes host materials and guest materials, the host materials include hole transport materials and electron transport materials; a material of the electron functional layer is the same as the electron transport materials, and a material of the hole functional layer is the same as the hole transport materials; an energy value HOMOA of a highest occupied molecular orbital of the hole transport materials and an energy value HOMOB of a highest occupied molecular orbital of the electron transport materials satisfy: HOMOA?HOMOB>0.2 eV; and an energy value LUMOA of a lowest unoccupied molecular orbital of the hole transport materials and an energy value LUMOB of a lowest unoccupied molecular orbital of the electron transport materials satisfy: LUMOA?LUMOB>0.2 eV.

Abstract: An oil-soluble conductive agent and a preparation method therefor. Raw materials for preparing the oil-soluble conductive agent comprise the following components: 20 parts by weight of ethyl caprate or bis(2-ethylhexyl) sebacate, 1.8-2.2 parts by weight of ethyl methyl carbonate, and 2-8 parts by weight of fluorine-containing ion salt; and the fluorine-containing ion salt is selected from one or more of lithium bis(trifluoromethanesulfonyl)imide, lithium trifluoromethanesulfonate, and lithium tetrafluoroborate. The oil-soluble conductive agent is apparently a colorless transparent liquid at 25° C. or higher, and the conductivity at 25° C. reaches 1×10?4 S/cm. The oil-soluble conductive agent can be completely dissolved in a base oil and improve the conductivity thereof, so as to have the effects of arc suppression, being anti-static, cooling, heat transfer, and conduction.

Abstract: A method includes obtaining, by a data analytics device, data of a terminal on an access device and data of the terminal on an access and mobility management function device, where the data of the terminal on the access device includes a first identifier, and the access device is an access device, the data of the terminal on the access and mobility management function device includes the first identifier, and the first identifier includes an identifier assigned by the access device to the terminal, associating, by the data analytics device, the data of the terminal on the access device with the data of the terminal on the access and mobility management function device based on the first identifier.

Abstract: Embodiments of the present application provide a battery, comprising: a box comprising an electrical cavity; a battery cell accommodated in the electrical cavity, a first wall of the battery cell being provided with a pressure relief mechanism; a first pathway and a second pathway, the first pathway and the second pathway being configured to be capable of communicating with an interior of the battery cell via the pressure relief mechanism when the pressure relief mechanism is actuated, wherein the first pathway is used to discharge emissions discharged from the pressure relief mechanism into the electrical cavity, and the second pathway is used to discharge the emissions discharged from the pressure relief mechanism out of the electrical cavity; a first balance valve for discharging emissions passing through the first pathway out of the box; and a second balance valve for discharging emissions passing through the second pathway out of the box.

Abstract: Methods of assessing cytolysis of cancer cells are provided, which include: providing a cell-substrate impedance monitoring device operably connected to an impedance analyzer, adding target cells characterized as cancer cells to a well of the device adding effector cells to the well to form a test well, where the effector cells are immune cells obtained or derived from a same patient as the target cells; monitoring cell-substrate impedance of the test well before and after adding the effector cells and optionally deriving an impedance-based parameter from the impedance; and determining effectiveness of effector cell killing of the target cells by comparing the impedance or impedance-based curves over time.

Abstract: Provided are a battery, an electric apparatus, a method for preparing battery, and an apparatus for preparing battery. The battery includes: a plurality of battery cells, including first battery cells and second battery cells, where a pressure relief mechanism is provided on both a first wall of the first battery cell and a second wall of the second battery cell; and a thermal management component, configured to accommodate fluid to regulate temperatures of the plurality of battery cells, where the thermal management component is attached to the first wall of the first battery cell and a first wall of the second battery cell, and is provided with a pressure relief region at a position corresponding to the pressure relief mechanism of the first battery cell, to discharge emissions from the first battery cell when the pressure relief mechanism of the first battery cell is actuated.

Abstract: Provided are a determination method and apparatus of a main shaft bearing state, an electronic device, and a storage medium. The method includes the following steps: Bearing swing data of a target main shaft bearing at multiple moments within a preset time period are acquired; at least one current data period and current-period bearing swing data in each current data period are determined according to the multiple pieces of bearing swing data; a first abrupt change value and a second abrupt change value are determined according to the current-period bearing swing data in each current data period; and a main shaft bearing state of the target main shaft bearing is determined according to the first abrupt change value and the second abrupt change value.

Abstract: An embodiment of this application provides a battery, a method for manufacturing same, and an electrical device. The battery includes: a plurality of battery cells arranged along a first direction. Each of the battery cells includes two first side faces disposed opposite to each other in the first direction, two second side faces disposed opposite to each other in a second direction, a top face and a bottom face disposed opposite to each other in a third direction, and two electrode terminals. The first direction, the second direction, and the third direction are orthogonal to each other. The first side faces are larger than the second side faces in area. The battery further includes a cooling component. The cooling component contains a cooling medium to cool the battery cells, and includes a cooling unit and an integrated unit.

Abstract: A high-pressure SCR system with venting and pressure-stabilizing for marine diesel engine, comprising an SCR reactor, a gas intake pipeline, an exhaust pipeline, a bypass pipeline, a pneumatic pipeline, first and second auxiliary pipelines When denitrification treatment is needed, the exhaust gas can enter from a flue gas inlet, sequentially pass through the gas intake pipeline, the SCR reactor, and the exhaust pipeline, and be discharged from a flue gas outlet. When denitrification treatment is not needed, the exhaust gas can enter the bypass pipeline from the flue gas inlet and be discharged from the flue gas outlet, the exhaust gas in the SCR reactor and exhaust pipeline being pushed by compressed air entering from the first and second auxiliary pipelines to be discharged from the flue gas outlet. Also provided is a ship.

Abstract: A multifunctional immunity-targeted micromolecule anti-cancer medicine Citrate Bestazomib and preparation method and application thereof. The structure of the multifunctional immunity-targeted micromolecule anti-cancer medicine Bestazomib Citrate is shown as follows: The multifunctional immunity-targeted micromolecule anti-cancer medicine Citrate Bestazomib has an activity-inhibiting effect on APN/CD13, also has an activity-inhibiting effect on tumor proteasome, and can be applied to the development of medicines for treating malignant tumors.

Abstract: A system for electronically and optically monitoring biological samples, the system including: a multi-well plate having a plurality of wells configured to receive a plurality of biological samples, each of the wells having a set of electrodes and a transparent window on a bottom surface of the well that is free of electrodes; an illumination module configured to illuminate the wells; a cradle configured to receive the multi-well plate, the cradle having an opening on the bottom that exposes the transparent windows of the wells; and an optical imaging module movable across different wells of a same multi-well plate to capture images through the windows.

Abstract: In a computer-implemented method for improving performance of a database optimizer, a processor calculates a first execution time for a database query executing through a first access path of a database system. A processor generates a second access path. A processor determines a second execution time via a simulation of the database query through the second access path. A processor determines that the second execution time is less than the first execution time. A processor, responsive to determining that the second execution time is less than the first execution time, sends the second access path to the database optimizer.