Patents by Inventor Xiaocheng Chen

Xiaocheng Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20180000964
    Abstract: The present invention relates to antibodies that bind to receptors expressed on the blood brain barrier and methods of using the same.
    Type: Application
    Filed: June 9, 2017
    Publication date: January 4, 2018
    Applicant: Genentech, Inc.
    Inventors: Christine Tan, Ryan J. Watts, Joy Yu Zuchero, Xiaocheng Chen, Mark S. Dennis
  • EXPRESSION AND SECRETION SYSTEM
    Publication number: 20170369869
    Abstract: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
    Type: Application
    Filed: August 30, 2017
    Publication date: December 28, 2017
    Inventors: Devin TESAR, Xiaocheng CHEN, Mark DENNIS, Isidro HOTZEL
  • Expression and secretion system
    Patent number: 9803191
    Abstract: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: October 31, 2017
    Assignee: Genentech, Inc.
    Inventors: Devin Tesar, Xiaocheng Chen, Mark Dennis, Isidro Hotzel
  • IMMUNOCONJUGATES COMPRISING ANTI-HER2 ANTIBODIES AND PYRROLOBENZODIAZEPINES
    Publication number: 20170274092
    Abstract: The invention provides immunoconjugates comprising anti-HER2 antibodies and methods of using the same.
    Type: Application
    Filed: February 21, 2017
    Publication date: September 28, 2017
    Applicant: GENENTECH, INC.
    Inventors: Xiaocheng Chen, Mark Dennis, Jagath Reddy Junutula, Gail Lewis Phillips, Thomas Harden Pillow, Mark X. Sliwkowski
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20170204194
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: March 29, 2017
    Publication date: July 20, 2017
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, Jr., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU
  • ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20170174782
    Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: October 18, 2016
    Publication date: June 22, 2017
    Applicant: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark Dennis, Jagath Reddy Junutula, Gail Lewis Phillips, Thomas Harden Pillow, Mark X. Sliwkowski
  • ANTI-CLL-1 ANTIBODIES AND METHODS OF USE
    Publication number: 20160368994
    Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
    Type: Application
    Filed: June 14, 2016
    Publication date: December 22, 2016
    Applicant: Genentech, Inc.
    Inventors: Robert F. Kelley, Steven R. Leong, Wei-Ching Liang, Mary Mathieu, Andrew G. Polson, Bing Zheng, Xiaocheng Chen, Cecilia Pui Chi Chiu, Mark S. Dennis, Allen Ebens, Yan Wu
  • Anti-HER2 antibodies and immunoconjugates
    Patent number: 9518118
    Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: December 13, 2016
    Assignee: Genentech, Inc.
    Inventors: Xiaocheng Chen, Mark Dennis, Jagath Reddy Junutula, Gail Lewis Phillips, Thomas Harden Pillow, Mark X. Sliwkowski
  • ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20160096893
    Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: September 11, 2015
    Publication date: April 7, 2016
    Applicant: GENENTECH, INC.
    Inventors: Xiaocheng Chen, Mark Dennis, Jagath Reddy Junutula, Gail Lewis Phillips, Thomas Harden Pillow, Mark X. Sliwkowski
  • ANTIBODY COMPOSITIONS AND METHODS OF USE
    Publication number: 20150376265
    Abstract: The invention provides compositions comprising anti-gH antibodies and anti-Complex I antibodies as well as methods of using the same.
    Type: Application
    Filed: December 19, 2014
    Publication date: December 31, 2015
    Applicant: GENENTECH, INC.
    Inventors: Xiaocheng Chen, Mark Dennis, Becket L. Feierbach, Ashley Fouts, Isidro Hotzel, Bing Li, Jo-Anne S. Hongo, Rajesh Vij
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20150166661
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 18, 2015
    Applicant: GENENTECH, INC.
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, JR., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU, Liping L. SUN
  • EXPRESSION AND SECRETION SYSTEM
    Publication number: 20140011981
    Abstract: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
    Type: Application
    Filed: July 3, 2013
    Publication date: January 9, 2014
    Applicant: GENENTECH, INC.
    Inventors: Devin Tesar, Xiaocheng Chen, Mark Dennis, Isidro Hotzel
  • ANTIBODY COMPOSITIONS AND METHODS OF USE
    Publication number: 20120082666
    Abstract: The invention provides compositions comprising anti-gH antibodies and anti-Complex I antibodies as well as methods of using the same.
    Type: Application
    Filed: September 29, 2011
    Publication date: April 5, 2012
    Inventors: Xiaocheng Chen, Mark Dennis, Becket Feierbach, Ashley Fouts, Isidro Hotzel, Bing Li