Patents by Inventor Xiaofeng Liu
Xiaofeng Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12366707Abstract: A graded-index polymer waveguide (30) and a manufacturing method thereof are provided. The method includes providing a waveguide substrate (1); manufacturing a waveguide lower cladding layer (2) on a surface of the waveguide substrate (1); coating a material of a waveguide core layer (3) having UV photosensitivity on a surface of the waveguide lower cladding layer (2) away from the waveguide substrate (1); performing a hot imprinting process for the material of the waveguide core layer by means of a flexible transfer film mold and forming a waveguide core layer (3) having an imprinted waveguide link structure; performing a heat treatment process for the waveguide core layer (3); performing a pre-exposure process for the waveguide core layer; coating a waveguide upper cladding layer on a surface of a waveguide core layer (3); and curing the waveguide core layer (3) and the waveguide upper cladding layer (4).Type: GrantFiled: October 31, 2022Date of Patent: July 22, 2025Assignee: SHENNAN CIRCUITS CO., LTD.Inventors: Xiaofeng Liu, Guodong Wang, Hua Miao, Tengfei Yao, Rui Wang, Yongkai Li
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Patent number: 12339052Abstract: A refrigerator is provided. The refrigerator includes a refrigerator body, a door body and an ice making compartment. The refrigerator body includes a storage compartment. The door body is configured to open or close the storage compartment. The ice making compartment is disposed in the storage compartment, and includes an ice making compartment shell, an ice maker, and an ice storage box. The ice maker is configured to make ice cubes. The ice storage box is located below the ice maker, and is configured to store the ice cubes made by the ice maker. The ice storage box includes a box body and a first ice baffle. At least a part of the first ice baffle is located in the box body, and the first ice baffle is configured to prevent the ice cubes from accumulating at a position of the box body close to the door body.Type: GrantFiled: December 30, 2021Date of Patent: June 24, 2025Assignee: HISENSE RONSHEN (GUANGDONG) REFRIGERATOR CO., LTD.Inventors: Huimin Yao, Jinbo Gan, Kunxiong Deng, Xiaofeng Liu, Zixuan Zhao, Hao Weng
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Patent number: 12327613Abstract: Computer-implemented methods of designing an antibody that will bind to a target epitope are disclosed. In one arrangement, the method comprises identifying one or more hotspot residues that will each bind to a corresponding one of one or more hotspot sites on the target epitope. Candidate antibody structures are selected from a database such that characteristic atoms within the antibody structure and hotspot characteristic atoms can be superimposed computationally with an averaged spatial deviation less than a predetermined threshold. A designed antibody is generated by replacing matching residues with different residues such that a predicted affinity is increased.Type: GrantFiled: December 1, 2016Date of Patent: June 10, 2025Assignee: UCB BIOPHARMA SRLInventors: Terence Seward Baker, Xiaofeng Liu, Jiye Shi, Richard David Taylor
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Patent number: 12296877Abstract: A safety information supervision apparatus applied to a high-speed rail signaling system includes a communication processor, a Radio Block Center (RBC) interface machine, a Centralized Traffic Control (CTC) interface machine, a supervision and analysis server, an analysis terminal, and a storage device, where the communication processor and the RBC interface machine are communicatively connected to the supervision and analysis server through a monitoring network. The CTC interface machine is communicatively connected to the CTC system of a station and the supervision and analysis server, so as to obtain train information in the CTC system and to transmit an analysis result of the supervision and analysis server to the CTC system through the CTC interface machine. Multi-source data fusion analysis is used to perform filtering and validity analysis on basic data, thereby reducing false alarms.Type: GrantFiled: September 24, 2021Date of Patent: May 13, 2025Assignee: CASCO SIGNAL CO., LTD.Inventors: Enhua Hu, Pengfei Tu, Xiangbo Yang, Xiaofeng Liu, Xingyu Zhou
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Publication number: 20250143020Abstract: A light-emitting diode includes a semiconductor epitaxial structure which includes a first semiconductor layer, an active layer, and a second semiconductor layer that are stacked in sequence. The second semiconductor layer includes a current spreading layer, which includes a first doped layer doped with a first p-type impurity, a second doped layer doped with the first p-type impurity and a second p-type impurity, and a third doped layer doped with the second p-type impurity. A concentration of the first p-type impurity in the first doped layer is less than or equal to a concentration of the first p-type impurity in the second doped layer. A concentration of the second p-type impurity in the third doped layer is greater than a concentration of the second p-type impurity in the second doped layer. A light-emitting device including the aforesaid light-emitting diode is also provided.Type: ApplicationFiled: October 29, 2024Publication date: May 1, 2025Inventors: Weihuan LI, Fuyang NING, Liwei WANG, Kunhuang CAI, Han-Xin LIU, Xiaofeng LIU, Lingfei WANG, Yuehua JIA
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Publication number: 20250143019Abstract: A light-emitting device includes a semiconductor epitaxial unit having a first surface and a second surface that are opposite to each other, and including a first semiconductor layer, an active layer, and a second semiconductor layer that are disposed sequentially in such order in a direction from the first surface to the second surface. The active layer includes a quantum well structure that has n periodic units, each of which includes a well layer and a barrier layer that are sequentially disposed. The second semiconductor layer includes a cladding layer and a current spreading layer. A ratio of a thickness of the current spreading layer to a current density of the light-emitting device ranges from 0.6 to 4. A light-emitting apparatus is also provided in the disclosure.Type: ApplicationFiled: July 12, 2024Publication date: May 1, 2025Inventors: Weihuan LI, Fuyang NING, Liwei WANG, Kunhuang CAI, Xiaofeng LIU, Jin-Dong WEI, Han-Xin LIU
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Publication number: 20250102507Abstract: A method for providing a composite image of a single biological sample, comprising the steps of generating a first image of the biological sample with a target protein, generating a second image of the biological sample with a target nucleic acid sequence, and generating a composite image that provides the relative locations of both the target protein and the target nucleic acid sequence. Also provided is a method of analyzing a biological sample, comprising providing a composite image of the biological sample according to the method for providing a composite image, and analyzing the expression of the protein and the nucleic acid sequences of interest from the composite image. Further provided are systems and kits that comprise the means for executing the novel methods.Type: ApplicationFiled: August 30, 2024Publication date: March 27, 2025Inventors: Antti E. SEPPO, Fiona GINTY, Kevin B. KENNY, David Lavan HENDERSON, Michael J. GERDES, Adriana I. LARRIERA MORENO, Xiaofeng LIU, Alex D. CORWIN, Stephen E. ZINGELEWICZ, Thomas HA, Natalia R. JUN, Ainura KYSHTOOBAYEVA, Denise A. HOLLMAN-HEWGLEY, Ying LI
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Patent number: 12247059Abstract: Conjugates of an interleukin-2 (“IL-2”) moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the non-peptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, methods of administering compositions to an individual, nucleic acid sequences, expression systems, host cells, and methods for preparing IL-moieties.Type: GrantFiled: July 12, 2021Date of Patent: March 11, 2025Assignee: Nektar TherapeuticsInventors: Mary J. Bossard, Cherie F. Ali, Xiaofeng Liu, Deborah H. Charych, Yujun Wang
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Publication number: 20250053558Abstract: A data consistency control method, applied to a centralized railway signal monitoring system, includes: acquiring, by a center of the centralized railway signal monitoring system, all data in a local and target time intervals; encoding, by the center, all the acquired data according to a type of the data to generate a first data consistency identifier; sending, by the center, a data consistency detection command to a station, and inquiring, by the station, all the data in the local and target time intervals upon receiving the command and encoding the data to generate a second data consistency identifier, and returning the second data consistency identifier to the center; and comparing, by the center, the first data consistency identifier with the second data consistency identifier, and finishing data consistency control in a case that the first data consistency identifier and the second data consistency identifier that are compared are consistent.Type: ApplicationFiled: November 11, 2022Publication date: February 13, 2025Inventors: Xiaofeng LIU, Xiangbo YANG, Enhua HU, Pengfei TU
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Publication number: 20250050925Abstract: Disclosed in the present disclosure is an intelligent browsing apparatus based on railway centralized signaling monitoring system data, including: an interface module, configured to send out an analysis command and display a received analysis result; and a data analysis module, connected to the interface module, and configured to acquire railway centralized signaling monitoring system data to be analyzed according to the received analysis command and analyze the railway centralized signaling monitoring system data to obtain and feed the analysis result back to the interface module. The intelligent browsing apparatus can automatically analyze the railway centralized signaling monitoring system data.Type: ApplicationFiled: November 9, 2022Publication date: February 13, 2025Inventors: Aie LIAN, Jing LIAO, Xingyu ZHOU, Xiaofeng LIU, Enhua HU, Xiangbo YANG, Pengfei TU
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Publication number: 20250051388Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.Type: ApplicationFiled: July 9, 2024Publication date: February 13, 2025Applicant: REATA PHARMACEUTICALS HOLDINGS, LLCInventors: Eric ANDERSON, Xiaofeng LIU, Andrea DECKER
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Patent number: 12221196Abstract: The present disclosure relates to the field of underwater robots, and in particular to a controllable sinking and floating swimming pool robot and a sinking and floating control method for a swimming pool robot. The controllable sinking and floating swimming pool robot of the present disclosure includes a sinking and floating control unit configured to control a swimming pool robot to float and sink; a waterline detection unit configured to detect a positional relationship between the swimming pool robot and a waterline of a liquid surface of a swimming pool where the swimming pool robot is located; and a main control unit configured to control a working state of the sinking and floating control unit to enter a floating working state based on detection results to realize a floating of the swimming pool robot.Type: GrantFiled: September 2, 2024Date of Patent: February 11, 2025Assignee: Aiper Global Pte. Ltd.Inventors: Xiaofeng Liu, Yongfei Hua
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Patent number: 12219385Abstract: Disclosed in the present application is a hybrid automatic repeat request feedback method, which comprises the steps that: an HARQ-ACK codebook includes HARQ-ACK information of M PDSCHs, the M PDSCHs are all scheduled by first-type PDCCHs, and the first-type PDCCHs are used for activating an SPS configuration; the order of the HARQ-ACK information of the M PDSCHs in the HARQ-ACK codebook is arranged according to at least one parameter value among cell indexes, BWP indexes, SPS configuration indexes and PDSCH transmission moments of the M PDSCHs. The embodiments of the present application also provide a hybrid automatic repeat request feedback method with the participation of second-type PDCCHs for releasing SPS and dynamically configured third-type PDCCHs. The present application also provides a terminal device and a network device to which the method is applied. The present application solves the problem of how to generate an HARQ-ACK codebook when there are multiple PDSCHs in an SPS configuration condition.Type: GrantFiled: August 14, 2020Date of Patent: February 4, 2025Assignee: China Academy of Information and CommunicationsInventors: Zhiyu Yan, Zhiqin Wang, Ying Du, Xiaofeng Liu, Guiming Wei, Fei Xu, Xia Shen, Huiying Jiao
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Patent number: 12203917Abstract: The present disclosure provides a method for determining an ore-forming environment of a porphyry deposit based on a tourmaline component, including the following steps: collecting a tourmaline-containing rock in the porphyry deposit to obtain a rock sample; performing pretreatment on the rock sample to obtain a treated sample; performing an in-situ tourmaline trace element test on the treated sample to obtain a test result; performing data processing and interpretation on the test result to obtain tourmaline trace element data; establishing a discrimination factor based on the tourmaline trace element data; and determining the ore-forming environment based on the discrimination factor. The present disclosure can quickly recognize a forming environment of a newly discovered porphyry deposit, thereby summarizing a rule and quickly giving guidance for a next prospecting direction.Type: GrantFiled: March 7, 2024Date of Patent: January 21, 2025Assignees: CHINA UNIVERSITY OF GEOSCIENCES (BEIJING), Tibet Julong Copper Co., Ltd.Inventors: Youye Zheng, Jianzhou Yi, Peng Liu, Song Wu, Xiaofang Dou, Quansheng Shen, Zhixin Zhang, Jinling Liao, Jiancuo Luosang, Defu Shu, Qiong Ci, Xiaofeng Liu
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Publication number: 20250012775Abstract: In a method for discriminating deposit types by using tourmaline elemental components, contents of Sn, Li, Ga, and V trace elements are determined by collecting hydrothermal tourmaline samples in a deposit, and deposit type discrimination is performed with F1, F2, and F3 as discriminant factors, in combination with the characteristics that a porphyry type Cu—Mo—Au deposit has lower contents of Sn+Li, and further, a porphyry type Cu—Mo deposit has higher contents of Ga*V, while a porphyry type Au deposit has relatively low contents of Ga*V; a granite-related Sn—W deposit has relatively high contents of Sn+Li; while an IOCG deposit has relatively high contents of Sn+Li and Ga*V, realizing quick discrimination of the deposit types during prospecting and exploration, shortening the exploration period and reducing the exploration cost, and the method can be used for identification of 4 different types of deposits.Type: ApplicationFiled: November 8, 2023Publication date: January 9, 2025Applicant: CHINA UNIVERSITY OF GEOSCIENCES (BEIJING)Inventors: Youye ZHENG, Peng LIU, Qiong CI, Xiaofang DOU, Song WU, Xiaofeng LIU, Fuzhi GONG
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Publication number: 20250012716Abstract: A method for rapid prediction of porphyry copper mineralization potential based on spectral characteristics of tourmaline, includes collecting and collating data related to magma-fluid evolution, petrography and mineralogy of a porphyry copper deposit in a working area, systematically, distinguishing magmatic tourmaline from hydrothermal tourmaline in the working area, and further distinguishing phases and generations of the hydrothermal tourmaline; collecting hydrothermal tourmaline samples of the same phase and generation; performing short-wave infrared spectroscopy measurement on the collected hydrothermal tourmaline samples; extracting spectral characteristics of the Fe—OH wavelength and Mg—OH wavelength of the tourmaline samples based on The Spectral Geologist (TSG); and when the Fe—OH wavelength is less than 2245.75 nm, and the Mg—OH wavelength is greater than 2356.Type: ApplicationFiled: October 24, 2023Publication date: January 9, 2025Applicants: CHINA UNIVERSITY OF GEOSCIENCES (BEIJING), Tibet Julong Copper Co., Ltd.Inventors: Youye ZHENG, Hongjun CHENG, Jiancuo LUOSANG, Jiangang WEI, Xiaofang DOU, Qiong CI, Xiaofeng LIU, Zhuoga SUOLANG, Song WU
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Publication number: 20250011473Abstract: The present invention relates to the area of improved anti-IgE antibodies and antigen binding agents, and compositions thereof, which target IgE, for instance: for use in treating disorders caused by IgE (such as allergic responses, or certain autoimmune responses); and, in particular, disorders caused by the interaction of IgE with the Fc?RI receptor. In particular, this invention relates to improved anti-IgE antibodies and antigen binding agents related to novel mutants of omalizumab (Xolair®). The improved anti-IgE antibodies and antigen binding agents of the invention may have improved affinity for IgE and/or an improved interaction with the C?2 domain of IgE and/or an improved modified epitope on IgE (for instance further involving the C?2 domain of IgE) and/or the ability to disassociate IgE from the Fc?RI receptor for instance at pharmaceutically-relevant concentrations.Type: ApplicationFiled: June 26, 2024Publication date: January 9, 2025Inventors: Ralph ADAMS, Thomas Allen CESKA, Anna Marie DAVIES, Alistair James HENRY, Xiaofeng LIU, James Michael MCDONNELL, Brian John SUTTON, Marta Katarzyna WESTWOOD
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Patent number: 12182054Abstract: The present disclosure provides a parallel bus-based communication system, the system including: electronic devices; a host controller equipped with a selecting chip and a communication chip, and the communication chip controls at least one channelized parallel bus, and the electronic devices are individually connected to the channelized parallel bus. The host controller, upon first power on, allocates addresses to the electronic device sequentially via the selecting chip. In the present disclosure, the communication chip of the communication system employs a parallel bus communication mode, and the selecting chip sequentially allocates addresses to the electronic device. Communication functions can be achieved by using a small number of communication chips. The electronic devices (sensors) are independent of each other and do not affect one another. The existing sensor structures and vehicle harness may be used, which has cost advantages.Type: GrantFiled: December 15, 2021Date of Patent: December 31, 2024Assignee: ZONGMU TECHNOLOGY (SHANGHAI) CO., LTD.Inventors: Dong Chen, Xiaofeng Liu, Hongfeng Zhu
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Patent number: D1065940Type: GrantFiled: June 7, 2023Date of Patent: March 11, 2025Inventor: Xiaofeng Liu
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Patent number: D1068767Type: GrantFiled: February 5, 2024Date of Patent: April 1, 2025Inventors: Yang Li, Xiaofeng Liu, Dahe Chen