Abstract: A light-emitting device includes a semiconductor epitaxial unit having a first surface and a second surface that are opposite to each other, and including a first semiconductor layer, an active layer, and a second semiconductor layer that are disposed sequentially in such order in a direction from the first surface to the second surface. The active layer includes a quantum well structure that has n periodic units, each of which includes a well layer and a barrier layer that are sequentially disposed. The second semiconductor layer includes a cladding layer and a current spreading layer. A ratio of a thickness of the current spreading layer to a current density of the light-emitting device ranges from 0.6 to 4. A light-emitting apparatus is also provided in the disclosure.

Abstract: A light-emitting diode includes a semiconductor epitaxial structure which includes a first semiconductor layer, an active layer, and a second semiconductor layer that are stacked in sequence. The second semiconductor layer includes a current spreading layer, which includes a first doped layer doped with a first p-type impurity, a second doped layer doped with the first p-type impurity and a second p-type impurity, and a third doped layer doped with the second p-type impurity. A concentration of the first p-type impurity in the first doped layer is less than or equal to a concentration of the first p-type impurity in the second doped layer. A concentration of the second p-type impurity in the third doped layer is greater than a concentration of the second p-type impurity in the second doped layer. A light-emitting device including the aforesaid light-emitting diode is also provided.

Abstract: A method for providing a composite image of a single biological sample, comprising the steps of generating a first image of the biological sample with a target protein, generating a second image of the biological sample with a target nucleic acid sequence, and generating a composite image that provides the relative locations of both the target protein and the target nucleic acid sequence. Also provided is a method of analyzing a biological sample, comprising providing a composite image of the biological sample according to the method for providing a composite image, and analyzing the expression of the protein and the nucleic acid sequences of interest from the composite image. Further provided are systems and kits that comprise the means for executing the novel methods.

Abstract: Conjugates of an interleukin-2 (“IL-2”) moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the non-peptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, methods of administering compositions to an individual, nucleic acid sequences, expression systems, host cells, and methods for preparing IL-moieties.

Abstract: A data consistency control method, applied to a centralized railway signal monitoring system, includes: acquiring, by a center of the centralized railway signal monitoring system, all data in a local and target time intervals; encoding, by the center, all the acquired data according to a type of the data to generate a first data consistency identifier; sending, by the center, a data consistency detection command to a station, and inquiring, by the station, all the data in the local and target time intervals upon receiving the command and encoding the data to generate a second data consistency identifier, and returning the second data consistency identifier to the center; and comparing, by the center, the first data consistency identifier with the second data consistency identifier, and finishing data consistency control in a case that the first data consistency identifier and the second data consistency identifier that are compared are consistent.

Abstract: Disclosed in the present disclosure is an intelligent browsing apparatus based on railway centralized signaling monitoring system data, including: an interface module, configured to send out an analysis command and display a received analysis result; and a data analysis module, connected to the interface module, and configured to acquire railway centralized signaling monitoring system data to be analyzed according to the received analysis command and analyze the railway centralized signaling monitoring system data to obtain and feed the analysis result back to the interface module. The intelligent browsing apparatus can automatically analyze the railway centralized signaling monitoring system data.

Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.

Abstract: The present disclosure relates to the field of underwater robots, and in particular to a controllable sinking and floating swimming pool robot and a sinking and floating control method for a swimming pool robot. The controllable sinking and floating swimming pool robot of the present disclosure includes a sinking and floating control unit configured to control a swimming pool robot to float and sink; a waterline detection unit configured to detect a positional relationship between the swimming pool robot and a waterline of a liquid surface of a swimming pool where the swimming pool robot is located; and a main control unit configured to control a working state of the sinking and floating control unit to enter a floating working state based on detection results to realize a floating of the swimming pool robot.

Abstract: Disclosed in the present application is a hybrid automatic repeat request feedback method, which comprises the steps that: an HARQ-ACK codebook includes HARQ-ACK information of M PDSCHs, the M PDSCHs are all scheduled by first-type PDCCHs, and the first-type PDCCHs are used for activating an SPS configuration; the order of the HARQ-ACK information of the M PDSCHs in the HARQ-ACK codebook is arranged according to at least one parameter value among cell indexes, BWP indexes, SPS configuration indexes and PDSCH transmission moments of the M PDSCHs. The embodiments of the present application also provide a hybrid automatic repeat request feedback method with the participation of second-type PDCCHs for releasing SPS and dynamically configured third-type PDCCHs. The present application also provides a terminal device and a network device to which the method is applied. The present application solves the problem of how to generate an HARQ-ACK codebook when there are multiple PDSCHs in an SPS configuration condition.

Abstract: The present disclosure provides a method for determining an ore-forming environment of a porphyry deposit based on a tourmaline component, including the following steps: collecting a tourmaline-containing rock in the porphyry deposit to obtain a rock sample; performing pretreatment on the rock sample to obtain a treated sample; performing an in-situ tourmaline trace element test on the treated sample to obtain a test result; performing data processing and interpretation on the test result to obtain tourmaline trace element data; establishing a discrimination factor based on the tourmaline trace element data; and determining the ore-forming environment based on the discrimination factor. The present disclosure can quickly recognize a forming environment of a newly discovered porphyry deposit, thereby summarizing a rule and quickly giving guidance for a next prospecting direction.

Abstract: A method for rapid prediction of porphyry copper mineralization potential based on spectral characteristics of tourmaline, includes collecting and collating data related to magma-fluid evolution, petrography and mineralogy of a porphyry copper deposit in a working area, systematically, distinguishing magmatic tourmaline from hydrothermal tourmaline in the working area, and further distinguishing phases and generations of the hydrothermal tourmaline; collecting hydrothermal tourmaline samples of the same phase and generation; performing short-wave infrared spectroscopy measurement on the collected hydrothermal tourmaline samples; extracting spectral characteristics of the Fe—OH wavelength and Mg—OH wavelength of the tourmaline samples based on The Spectral Geologist (TSG); and when the Fe—OH wavelength is less than 2245.75 nm, and the Mg—OH wavelength is greater than 2356.

Abstract: The present invention relates to the area of improved anti-IgE antibodies and antigen binding agents, and compositions thereof, which target IgE, for instance: for use in treating disorders caused by IgE (such as allergic responses, or certain autoimmune responses); and, in particular, disorders caused by the interaction of IgE with the Fc?RI receptor. In particular, this invention relates to improved anti-IgE antibodies and antigen binding agents related to novel mutants of omalizumab (Xolair®). The improved anti-IgE antibodies and antigen binding agents of the invention may have improved affinity for IgE and/or an improved interaction with the C?2 domain of IgE and/or an improved modified epitope on IgE (for instance further involving the C?2 domain of IgE) and/or the ability to disassociate IgE from the Fc?RI receptor for instance at pharmaceutically-relevant concentrations.

Abstract: In a method for discriminating deposit types by using tourmaline elemental components, contents of Sn, Li, Ga, and V trace elements are determined by collecting hydrothermal tourmaline samples in a deposit, and deposit type discrimination is performed with F1, F2, and F3 as discriminant factors, in combination with the characteristics that a porphyry type Cu—Mo—Au deposit has lower contents of Sn+Li, and further, a porphyry type Cu—Mo deposit has higher contents of Ga*V, while a porphyry type Au deposit has relatively low contents of Ga*V; a granite-related Sn—W deposit has relatively high contents of Sn+Li; while an IOCG deposit has relatively high contents of Sn+Li and Ga*V, realizing quick discrimination of the deposit types during prospecting and exploration, shortening the exploration period and reducing the exploration cost, and the method can be used for identification of 4 different types of deposits.

Abstract: The present disclosure provides a parallel bus-based communication system, the system including: electronic devices; a host controller equipped with a selecting chip and a communication chip, and the communication chip controls at least one channelized parallel bus, and the electronic devices are individually connected to the channelized parallel bus. The host controller, upon first power on, allocates addresses to the electronic device sequentially via the selecting chip. In the present disclosure, the communication chip of the communication system employs a parallel bus communication mode, and the selecting chip sequentially allocates addresses to the electronic device. Communication functions can be achieved by using a small number of communication chips. The electronic devices (sensors) are independent of each other and do not affect one another. The existing sensor structures and vehicle harness may be used, which has cost advantages.

Abstract: The present disclosure provides a method for determining an ore-forming environment of a porphyry deposit based on a tourmaline component, including the following steps: collecting a tourmaline-containing rock in the porphyry deposit to obtain a rock sample; performing pretreatment on the rock sample to obtain a treated sample; performing an in-situ tourmaline trace element test on the treated sample to obtain a test result; performing data processing and interpretation on the test result to obtain tourmaline trace element data; establishing a discrimination factor based on the tourmaline trace element data; and determining the ore-forming environment based on the discrimination factor. The present disclosure can quickly recognize a forming environment of a newly discovered porphyry deposit, thereby summarizing a rule and quickly giving guidance for a next prospecting direction.

Abstract: A preparation method and use of a yellow fluorescent glass ceramic are disclosed. The preparation method includes: mixing a monomer, a cross-linking agent and a filling solvent evenly, then adding fumed silica and stirring evenly, further adding an ultraviolet (UV) photoinitiator and an UV absorber, and stirring thoroughly; adding a yellow phosphor (Y,Gd)AG:Ce, stirring thoroughly and defoaming to obtain a slurry; introducing the slurry into a mold, and curing by UV irradiation or three-dimensional (3D) printing to obtain a body; putting the body into a high-temperature furnace for heating to obtain a phosphor-embedded porous silica glass; putting the porous silica glass into a high-temperature vacuum furnace for densification and sintering to obtain a densified fluorescent glass ceramic; and finally cutting and surface-polishing.

Abstract: A pyrazole derivative, and a preparation method therefor and a use thereof in medicine are described. In particular, provided are a PRMT5 inhibitor having a structure shown in formula (I), a preparation method therefor, a pharmaceutical composition containing same, a use thereof as a PRMT5 inhibitor, and a use thereof in treatment and/or prevention of a PRMT5-mediated disease.

Abstract: The present invention provides antibodies comprising a variable (V) domain and an insert polypeptide, wherein the insert polypeptide is within the framework 3 region of the V domain.