Abstract: The present application provides anti-Sclerostin constructs that bind to Sclerostin, nucleic acid molecules encoding an amino acid sequence of the anti-Sclerostin construct, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of preparing the anti-Sclerostin construct, pharmaceutical compositions containing the anti-Sclerostin construct, and methods of using the anti-Sclerostin construct or compositions.

Abstract: Disclosed are a coffee capsule manufacturing tool and its manufacturing method. The coffee capsule manufacturing tool comprises a capsule shell, a mode base, a sealing film, a pressing mold, a powder-filling member, and a powder-pressing member. The opening of the capsule shell is provided with an outer ring extending outer towards. The center of the powder-filling member is penetrated with a powder guiding channel, a bottom portion is provided with a powder-filling member powder-filling holder, the powder-filling holder is supported on the outer ring, an inside wall of the powder guiding channel extends towards the capsule shell and extends beyond the powder-filling holder, when the powder-filling holder is supported on the outer ring, it extends into the capsule shell, the powder-pressing member extends into the powder guiding channel and uniformly compresses the coffee powder inside the capsule shell.

Abstract: A design method for high-performance ladle furnace (LF) desulfurization refining slag is provided, including: step S1: extracting a refining slag composition of LF desulfurization refining slag, and calculating a complete melting temperature and a viscosity of the refining slag composition; step S2: based on the refining slag composition and corresponding complete melting temperature and viscosity, calculating a desulfurization capacity of each refining slag composition, and determining a desulfurization range of the refining slag composition based on desulfurization capacity results; and step S3: selecting a high-performance LF desulfurization refining slag composition based on a desulfurization capacity range of the refining slag composition, analyzing a sulfur content in steel, and completing a design of the high-performance LF desulfurization refining slag.

Abstract: Provided are an appearance detection method and apparatus for a bare cell, a computer device, a computer-readable storage medium, a computer program product, and an appearance detection system for a bare cell, where the method includes: obtaining a cell picture of the bare cell by shooting, the cell picture being obtained by shooting in alignment with positions of tabs on an edge of the bare cell; determining a detection object in the cell picture; and performing appearance detection based on the detection object to obtain detection result information. The cell picture is obtained by shooting in alignment with the positions of the tabs on the edge of the bare cell, such that imaging of cell edges is parallel light reflection imaging.

Abstract: A simulation method of shield tunnel segment floating includes steps of dividing a flow field into grids, obtaining numbers and center coordinates of control bodies, and setting flow field boundary conditions; initializing flow field parameters and calculation parameters; updating the area velocity of the control bodies in the current time step; discretizing the flow field control equation, and solving iteratively the flow field velocity and pressure; updating the velocity and position coordinates of the boundary discrete points; obtaining the velocity of the boundary discrete points, calculating the force generated by the boundary discrete points and discretizing the force to the whole flow field; and finally transmitting the velocity of the boundary discrete points, the force applied to each unit of the flow field, the force applied to the boundary discrete points and the updated slurry viscosity in the current time step to the next time step.

Abstract: A friction resistance testing device for a side wall of a pipe jacking machine includes: a shell, a pressure gauge unit, a pulley (3) and a sensing block (4); wherein the pressure gauge unit, the pulley (3) and the sensing block (4) are provided in the shell (1); the pressure gauge unit is fixed to the shell (1); the pulley (3) is provided between the sensing block (4) and the pressure gauge unit; the sensing block (4) presses the pressure gauge unit in a horizontal direction to measure a side wall friction resistance; and the sensing block (4) presses the pressure gauge unit in a vertical direction to measure a soil pressure. The present invention further provides a method for adopting the friction resistance testing device for the side wall of the pipe jacking machine.

Abstract: A method for lifting a subway shield tunnel by polymer grouting includes steps of: detecting settlement of the shield tunnel, and determining a settlement location, a settlement range and a settlement amount; drilling a row of isolation barrier holes on both sides of a settlement repair area, and injecting quick-setting slurry so that two isolation barriers are formed; drilling grouting channel holes from ground, and then drilling horizontal grouting holes below the settlement; connecting grouting pipes to geotextile bags, and feeding the geotextile bags into each of the grouting holes in turn; using a polymer grouting system to inject polymer slurry into the geotextile bags, wherein the polymer slurry then expands to lift up a soil layer above and jack up a tunnel structure; and after lifting, filling and sealing the grouting channel holes. The method is efficient and convenient without the need for maintenance.

Abstract: The present application provides anti-Sclerostin constructs that bind to Sclerostin, nucleic acid molecules encoding an amino acid sequence of the anti-Sclerostin construct, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of preparing the anti-Sclerostin construct, pharmaceutical compositions containing the anti-Sclerostin construct, and methods of using the anti-Sclerostin construct or compositions.

Abstract: The present invention provides novel compounds having the general formula: wherein R1, R2, R3, R4, A1, A2, A3, and A4 are as described herein, or a pharmaceutically acceptable salt thereof, compositions including the compounds and methods of using the compounds.

Abstract: Provided are a photoelectric hybrid device based on glass waveguide and manufacturing method thereof. The device comprises a first organic substrate, a glass substrate and a photoelectric chip; an inner side of an upper surface of the glass substrate is provided with a glass waveguide and an electrical interconnection structure communicating the upper surface and a lower surface of the glass substrate; the photoelectric chip is installed on an outer side of the upper surface of the glass substrate, an electrical connection port of the photoelectric chip is connected with the electrical interconnection structure, and an optical connection port of the photoelectric chip is arranged opposite to a first end of the glass waveguide; and the lower surface of the glass substrate is connected with the first organic substrate, and also connected with the first conductive trace arranged in the first organic substrate through the electrical interconnection structure.

Abstract: A semiconductor light-emitting component includes a semiconductor epitaxial structure that includes a first conductivity type semiconductor layer, an active layer, and a second conductivity type semiconductor layer. The first conductivity type semiconductor layer includes a first current spread layer having a first and second parts which are stacked on one another. The first part has an average band gap greater than that of the second part. The second part is formed by alternately stacking first sub layers and second sub layers one on another. Each of the first sub layers has a band gap different from that of each of the second sub layers. A light-emitting device including the semiconductor light-emitting component is also disclosed.

Abstract: In a method for discriminating deposit types by using tourmaline elemental components, contents of Sn, Li, Ga, and V trace elements are determined by collecting hydrothermal tourmaline samples in a deposit, and deposit type discrimination is performed with F1, F2, and F3 as discriminant factors, in combination with the characteristics that a porphyry type Cu—Mo—Au deposit has lower contents of Sn+Li, and further, a porphyry type Cu—Mo deposit has higher contents of Ga*V, while a porphyry type Au deposit has relatively low contents of Ga*V; a granite-related Sn—W deposit has relatively high contents of Sn+Li; while an IOCG deposit has relatively high contents of Sn+Li and Ga*V, realizing quick discrimination of the deposit types during prospecting and exploration, shortening the exploration period and reducing the exploration cost, and the method can be used for identification of 4 different types of deposits.

Abstract: A scene switching method includes: determining whether a user moves from a first scene to a second scene or not; if yes, acquiring voiceprint information of the user in the second scene; determining each device to be switched in the first scene according to the voiceprint information, and obtaining an operation state of the device to be switched; and determining an operation state of each target device in the second scene.

Abstract: Each sensor electrode includes transmission electrodes extending in a first direction, and reception electrodes extending in a second direction. Each of the transmission electrodes and the reception electrodes includes a mesh pattern formed by arranging a plurality of cells. Each cell has a quadrangular shape formed by a first diagonal and a second diagonal longer than the first diagonal. Each sensor electrode is configured so that the second diagonal extends in an extending direction of the sensor electrodes.

Abstract: The present application discloses a beam switching method for an intermediate node, applied to a wireless communication system. The wireless communication system includes a network device, an intermediate node apparatus, and user equipment. On a user node side, control information is received, wherein the control information includes a beam switching indication for the intermediate node; within a first threshold duration after receiving the control information, downlink control signaling and/or data are/is forwarded by using a beam controlled by an intermediate node before switching; and after a sum of the first threshold duration and a second threshold duration following receiving of the control information, the downlink control signaling and/or the data are/is forwarded by using a beam controlled by an intermediate node after switching. The present application further includes a device and system for implementing the method described.

Abstract: A data consistency control method, applied to a centralized railway signal monitoring system, includes: acquiring, by a center of the centralized railway signal monitoring system, all data in a local and target time intervals; encoding, by the center, all the acquired data according to a type of the data to generate a first data consistency identifier; sending, by the center, a data consistency detection command to a station, and inquiring, by the station, all the data in the local and target time intervals upon receiving the command and encoding the data to generate a second data consistency identifier, and returning the second data consistency identifier to the center; and comparing, by the center, the first data consistency identifier with the second data consistency identifier, and finishing data consistency control in a case that the first data consistency identifier and the second data consistency identifier that are compared are consistent.

Abstract: Conjugates of an interleukin-2 (“IL-2”) moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the non-peptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, methods of administering compositions to an individual, nucleic acid sequences, expression systems, host cells, and methods for preparing IL-moieties.