Abstract: The present disclosure provides a method for determining an ore-forming environment of a porphyry deposit based on a tourmaline component, including the following steps: collecting a tourmaline-containing rock in the porphyry deposit to obtain a rock sample; performing pretreatment on the rock sample to obtain a treated sample; performing an in-situ tourmaline trace element test on the treated sample to obtain a test result; performing data processing and interpretation on the test result to obtain tourmaline trace element data; establishing a discrimination factor based on the tourmaline trace element data; and determining the ore-forming environment based on the discrimination factor. The present disclosure can quickly recognize a forming environment of a newly discovered porphyry deposit, thereby summarizing a rule and quickly giving guidance for a next prospecting direction.

Abstract: A preparation method and use of a yellow fluorescent glass ceramic are disclosed. The preparation method includes: mixing a monomer, a cross-linking agent and a filling solvent evenly, then adding fumed silica and stirring evenly, further adding an ultraviolet (UV) photoinitiator and an UV absorber, and stirring thoroughly; adding a yellow phosphor (Y,Gd)AG:Ce, stirring thoroughly and defoaming to obtain a slurry; introducing the slurry into a mold, and curing by UV irradiation or three-dimensional (3D) printing to obtain a body; putting the body into a high-temperature furnace for heating to obtain a phosphor-embedded porous silica glass; putting the porous silica glass into a high-temperature vacuum furnace for densification and sintering to obtain a densified fluorescent glass ceramic; and finally cutting and surface-polishing.

Abstract: A pyrazole derivative, and a preparation method therefor and a use thereof in medicine are described. In particular, provided are a PRMT5 inhibitor having a structure shown in formula (I), a preparation method therefor, a pharmaceutical composition containing same, a use thereof as a PRMT5 inhibitor, and a use thereof in treatment and/or prevention of a PRMT5-mediated disease.

Abstract: The present invention provides antibodies comprising a variable (V) domain and an insert polypeptide, wherein the insert polypeptide is within the framework 3 region of the V domain.

Abstract: Disclosed are a coffee capsule manufacturing tool and its manufacturing method. The coffee capsule manufacturing tool comprises a capsule shell, a mode base, a sealing film, a pressing mold, a powder-filling member, and a powder-pressing member. The opening of the capsule shell is provided with an outer ring extending outer towards. The center of the powder-filling member is penetrated with a powder guiding channel, a bottom portion is provided with a powder-filling member powder-filling holder, the powder-filling holder is supported on the outer ring, an inside wall of the powder guiding channel extends towards the capsule shell and extends beyond the powder-filling holder, when the powder-filling holder is supported on the outer ring, it extends into the capsule shell, the powder-pressing member extends into the powder guiding channel and uniformly compresses the coffee powder inside the capsule shell.

Abstract: The present invention discloses a method for evaluating a metallogenic potential of a skarn deposit based on the magnetite composition, including collecting geological, geophysical, geochemical, and remote sensing data in a studying area, systematically, and delineating a favorable area for mineralization; collecting magnetite-bearing samples in the favorable area for mineralization, and describing the lithology, alteration and mineralization characteristics of each sample; selecting the most representative magnetite samples for chemical analysis to obtain average contents of trace elements Ti, Ni, V, K and Al+Si+Mg, denoted as c(Ti), c(Ni), c(V), c(K), and c(Al+Si+Mg) in ppm; and calculating discriminant factors F1, F2, F3, and F4 by substituting data, and performing discrimination; and when the four discriminant factors all discriminate the metallogenic potential to be better, determining the skarn deposit in the favorable area for mineralization to have a good metallogenic potential; and discriminating as

Abstract: A light emitting device includes an epitaxial structure and first and second electrodes on a side of the epitaxial structure. The epitaxial structure includes a first-type semiconductor layer, an active layer, and a second-type semiconductor layer. The active layer is disposed between the first-type semiconductor layer and the second-type semiconductor layer. The first electrode is disposed on the epitaxial structure to be electrically connected with the first-type semiconductor layer. The second electrode is disposed on the epitaxial structure to be electrically connected with the second-type semiconductor layer. The second electrode is in ohmic contact with a second-type window sublayer of the second-type semiconductor layer.

Abstract: Provided are a photoelectric hybrid device based on glass waveguide and manufacturing method thereof. The device comprises a first organic substrate, a glass substrate and a photoelectric chip; an inner side of an upper surface of the glass substrate is provided with a glass waveguide and an electrical interconnection structure communicating the upper surface and a lower surface of the glass substrate; the photoelectric chip is installed on an outer side of the upper surface of the glass substrate, an electrical connection port of the photoelectric chip is connected with the electrical interconnection structure, and an optical connection port of the photoelectric chip is arranged opposite to a first end of the glass waveguide; and the lower surface of the glass substrate is connected with the first organic substrate, and also connected with the first conductive trace arranged in the first organic substrate through the electrical interconnection structure.

Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.

Abstract: The present invention relates to the area of improved anti-IgE antibodies and antigen binding agents, and compositions thereof, which target IgE, for instance: for use in treating disorders caused by IgE (such as allergic responses, or certain autoimmune responses); and, in particular, disorders caused by the interaction of IgE with the Fc?RI receptor. In particular, this invention relates to improved anti-IgE antibodies and antigen binding agents related to novel mutants of omalizumab (Xolair®). The improved anti-IgE antibodies and antigen binding agents of the invention may have improved affinity for IgE and/or an improved interaction with the C?2 domain of IgE and/or an improved modified epitope on IgE (for instance further involving the C?2 domain of IgE) and/or the ability to disassociate IgE from the Fc?RI receptor for instance at pharmaceutically-relevant concentrations.

Abstract: The present application discloses an AI technology-based channel state information feedback method, including the following steps: indicating at least one to-be-used AI model by first information; indicating a first feedback period by second information; and processing CSI original data and generating result data by the selected AI model; wherein the first feedback period is used for transmitting the result data. The present application further includes apparatuses applying the method. The present application solves the problems of low CSI feedback accuracy and large signal codebook quantity in a traditional technology.

Abstract: A quick self-making tool for a coffee capsule includes a die holder and a pressing die. A die cavity for containing a capsule shell is formed in the die holder, a sealing film is laid on an opening of the capsule shell, the sealing film seals the opening of the capsule shell through pressing of the pressing die to make the coffee capsule, and a guide piece is arranged on the die holder, and is configured to guide the sealing film to be coaxially aligned with the capsule shell before being pressed and guide up-down vertical movement of the pressing die during pressing. The pressing die evenly press an outer ring of the capsule shell, the sealing effect of the sealing film and the capsule shell is improved, and the situation that the sealing film and the top face of the capsule shell are not combined firmly is avoided.

Abstract: A movable coffee capsule storage rack includes a rack body for storage of coffee capsules. A first bracket is fixed to the bottom of the rack body, a first caster is rotatably connected to the first bracket through a first rotating shaft, a second bracket is disposed adjacent to the support leg, a second caster is connected to a second end of the second bracket, and when the second bracket is driven to rotate by the handle to drive the second caster to move down to hold up the support leg, the rack body is entirely supported by the first caster and the second caster and realizes free sliding. With the structure of the present disclosure, the storage rack is allowed to be switched quickly between the fixed state and the moving state through the movement of the second caster, the structure is simple, and the operation is convenient.

Abstract: A preparation method and use of a green fluorescent transparent ceramic are disclosed. The preparation method includes: weighing, according to a stoichiometric ratio, elements present in Ca3-x-yCexAySc2-xBzSi3-mCmO12, in forms of oxides, carbonates or nitrates as raw materials; mixing the raw materials, annealing, melting at a high temperature, cooling and annealing at a low temperature; putting the glass into a high-temperature furnace, holding, raising the temperature, and performing crystallization and densification sintering; finally cutting, reducing and surface-polishing, where A is at least one from the group consisting of Lu, Y, Gd, La and Na; B is at least one from the group consisting of Zr, Hf and Mg; C is at least one from the group consisting of Al and P; x, y, z and m satisfy 0.001?x?0.06, 0?y?0.06, 0?z?0.06 and 0?m?0.3, respectively.

Abstract: The present invention provides antibodies comprising a variable (V) domain and an insert polypeptide, wherein the insert polypeptide is within the framework 3 region of the V domain.

Abstract: A light-emitting device includes: an epitaxial structure having a first surface and a second surface opposite to the first surface, and including a first type semiconductor layered unit that includes a first type window layer and a first type ohmic contact layer disposed at one side of the first type window layer; an active layer; and a second type semiconductor layered unit. The first type window layer is disposed between the first type ohmic contact layer and the active layer. The first type ohmic contact layer contains a material represented by Alx1Gay1InP, where 0?x1?1, 0?y1?1. The first type window layer contains a material represented by Alx2Gay2InP, where 0<x2?1, 0?y2?1. The first type ohmic contact layer has an Al content lower than an Al content of the first type window layer. A light-emitting apparatus that includes a light-emitting device according to the disclosure is also disclosed.