Abstract: The present disclosure discloses a conflict detection method for Internet of Things (IoT) device scheduling, relating to the technical field of the IoT, and specific steps include: acquiring data of a device model; converting a device scheduling instruction into a conditional instruction according to the data of the device model; determining a scheduling conflict rule according to device scheduling conflicts in historical data; detecting whether the conditional instruction is in a conflict state based on the scheduling conflict rule; if the conditional instruction is in a conflict state, performing a first conflict resolution, or if the conditional instruction is in a non-conflict state or after a conflict is resolved, performing a second detection; converting, in the second detection, the conditional instruction into an SMT formula, inputting the SMT formula into an SMT solver for detection, and determining whether the conditional instruction is in a conflict state; and if the conditional instruction is in a

Abstract: The present invention provides a method and system for analyzing precipitation normalization by gradient-based parameter optimization.

Abstract: Disclosed in the present invention are a polypeptide fragment, a derivative of the polypeptide fragment, and applications of the derivative of the polypeptide in the preparation of drugs for preventing and treating fibrosis diseases.

Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or pharmaceutically acceptable salts thereof wherein R, R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein. The disclosure also relates to methods of making and using compounds of Formula (I) or pharmaceutically acceptable salts thereof.

Abstract: The present invention provides compounds of the formula: wherein A, Z, G, R1, R2, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients for cancer.

Abstract: The present invention provides compounds of the formula: wherein A, Z, G, R1, R2, and R4 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients for cancer.

Abstract: A method for suppressing coherent and polarization-induced fading by simultaneous monitoring of loss and vibration is provided. By using merely common single-mode sensing fibers, the polarization diversity-based measurement method solves the conflict between ?-OTDR and COTDR in terms of polarization state. In addition, the method not only achieves a better coherent fading noise suppression effect but also enhances the capability of recognizing small loss events in the monitoring of loss parameters. Meanwhile, the method can suppress the influence of coherent fading on the phase demodulation of ?-OTDR and reconstruct a vibration signal with high fidelity in the monitoring of perturbation parameters, which can effectively reduce the error rate of external perturbation warning.

Abstract: The present invention provides an offline handwriting individual recognition system and method. The method comprises: scanning the suspicious handwriting to obtain a first white light image and a first three-dimensional image, and scanning the sample handwriting to obtain a second white light image and a second three-dimensional image; pre-processing the first white light image and the second white light image to obtain a first pre-processed image and a second pre-processed image; extracting a first skeleton image and a second skeleton image from the first pre-processed image and the second pre-processed image; obtaining a first writing trajectory and a second writing trajectory according to the first skeleton image and the second skeleton image; extracting a first dynamic feature, a first three-dimensional feature, and a second dynamic feature, a second three-dimensional feature; processing to obtain a correlation coefficient, and obtaining an individual recognition result.

Abstract: Disclosed in the present invention are a polypeptide fragment, a derivative of the polypeptide fragment, and applications of the derivative of the polypeptide in the preparation of drugs for preventing and treating fibrosis diseases.

Abstract: The present disclosure provides a preparation method of a titanium implant with a surface coating in a crater-like porous shape. A titanium substrate is subjected to polishing, cleaning, and first drying in sequence to obtain a pretreated titanium substrate. This step eliminates an influence of roughness and surface impurities of the titanium substrate on roughness and a structure of a coating formed on a surface of the titanium substrate after micro-arc oxidation, so as to obtain a titanium implant with a specific structure and a desirable biological performance. The micro-arc oxidation is conducted using the pretreated titanium substrate as an anode and iron as a cathode in an electrolyte containing sodium phosphate. In this step, a micro-arc oxidation coating is formed on the surface of the titanium substrate to obtain the titanium implant with a surface coating in a crater-like porous shape.

Abstract: A control method of a mechanical arm, a mechanical arm assembly, and a readable storage medium. The mechanical arm includes a parallel platform which includes a movable platform, a static platform and a telescopic element connecting the movable platform and the static platform, and the method includes: acquiring a current pose of the movable platform in a mechanical coordinate system, wherein the mechanical coordinate system is a global coordinate system of the mechanical arm where the movable platform is located; acquiring, according to the current pose of the movable platform, a target pose of a static platform in the mechanical coordinate system; performing pose transformation on the static platform according to the current pose of the movable platform and the target pose of the static platform.

Abstract: Disclosed is a copper-niobium alloy for a medical biopsy puncture needle. A needle core and/or needle tube of the puncture needle are/is made of the copper-niobium alloy. The copper-chromium alloy includes the following components by mass: 5?Nb?15 and the balance of Cu. A copper alloy with designed components is obtained by combining a diamagnetic material Cu with paramagnetic Nb, and compared with existing medical stainless steel and titanium alloy, the copper alloy has greatly reduced magnetic susceptibility, and specifically, the artifact area and volume are also significantly reduced. In addition, the blank of use of the copper alloy in medical biopsy paracentesis is filled.

Abstract: The present disclosure provides a fiber membrane and a preparation method and use thereof, and belongs to the field of biological materials. The fiber membrane includes a fiber with a core-shell structure, where a core of the fiber includes simvastatin and a first spinnable polymer, and a shell of the fiber includes hydroxyapatite and a second spinnable polymer. In the fiber, a release of the simvastatin mainly depends on a rate of water invasion. After water invades the fiber, the simvastatin in the fiber leaves the fiber with the diffusion of water. In the present disclosure, a barrier function of the shell prevents moisture from entering the core. Therefore, the simvastatin in the core cannot leave the fiber with the diffusion of water molecules in an early stage, and a release rate of drugs is slowed down in the early stage, thereby controlling sustained release of the drugs.

Abstract: The present disclosure provides a hydrophilic fiber membrane with a sustained-release drug, and belongs to the field of biological materials. The present disclosure provides a hydrophilic fiber membrane with a sustained-release drug, including a fiber with a core-shell structure, where a core of the fiber includes curcumin and a first spinnable polymer, and a shell of the fiber includes polyethylene glycol and a second spinnable polymer; and in the shell, the polyethylene glycol and the second spinnable polymer have a mass ratio of not greater than 1:12. In the present disclosure, the fiber membrane has a core-shell structure, the curcumin is provided in the core, and the shell prevents a rapid release of the curcumin in an early stage, thereby delaying a release rate of the curcumin to prevent the drug from forming a burst release in the early stage and causing toxic reactions.

Abstract: The present disclosure relates to compounds that are capable of modulating the WNT/Beta-Catenin pathway. The disclosure further relates to methods of treating colorectal cancer and other WNT/Beta-Catenin mediated cancers.

Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or pharmaceutically acceptable salts thereof wherein R, R1, R2, R3, R4, R5, R6, R7, and R8, are as defined herein. The disclosure also relates to methods of making and using compounds of Formula (I) or pharmaceutically acceptable salts thereof.

Abstract: A hybrid master-slave mapping method includes the following steps: acquiring a current position and a target position of an end point of a robotic arm; decomposing a displacement from the current position to the target position into a vertical direction and a horizontal plane to obtain a vertical displacement position and a horizontal displacement position; determining a first control amount of a multi-degree-of-freedom parallel platform according to the vertical displacement position, and determining a second control amount of a passive arm according to the horizontal displacement position; controlling the multi-degree-of-freedom parallel platform according to the first control amount, and controlling the passive arm according to the second control amount.