Patents by Inventor Xiaohui Chen
Xiaohui Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9399986Abstract: A device, a system, and a method for isolating biomolecules from biological materials are provided. The device comprises a quartz-based solid phase extraction matrix comprising one or more reagents impregnated therein; and an electroosmotic pump (EOP) operationally coupled to the quartz-based solid phase extraction matrix to elute the nucleic acids, wherein the EOP comprises a plurality of electroosmotic membranes comprising one or more positive electroosmotic membranes and one or more negative electroosmotic membranes disposed alternatively and a plurality of electrodes comprising one or more cathodes and one or more anodes, wherein at least one cathode is disposed on one side of one of the membranes and at least one anode is disposed on another side of that membrane and at least one cathode or anode is disposed between a positive electroosmotic membrane and a negative electroosmotic membrane.Type: GrantFiled: August 30, 2012Date of Patent: July 26, 2016Assignee: General Electric CompanyInventors: John Richard Nelson, Li Zhu, Xiaohui Chen, Christopher Michael Puleo, Patrick McCoy Spooner
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Patent number: 9347033Abstract: A method of processing an adipose tissue to collect adipose derived regenerative cells is provided, wherein the method comprises providing a vessel comprising a fluid jet mixer, introducing the adipose tissue into the vessel, introducing a buffer solution into the vessel; washing the adipose tissue using the fluid jet mixer; introducing an enzyme solution into the vessel; initiating jet mixing into the vessel comprising the adipose tissue, the enzyme solution, and the buffer solution using the fluid jet mixer to digest the adipose tissue to form a digestion product; phase-separating the digestion product into a digested buoyant fat layer and a non-buoyant aqueous layer; and collecting the non-buoyant aqueous layer comprising the adipose derived regenerative cells. A system of processing an adipose tissue to collect adipose derived regenerative cells is also provided.Type: GrantFiled: July 30, 2015Date of Patent: May 24, 2016Assignee: General Electric CompanyInventors: Zaeem Ashraf Khan, Aaron Joseph Dulgar-Tulloch, Stefan Rakuff, Philip Alexander Shoemaker, Erik Leeming Kvam, Xiaohui Chen, Jaydeep Roy
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Publication number: 20160137547Abstract: A leucite glass-ceramic is prepared from a glass comprising: about 66.8 to about 71.9 mol % of SiO2, about 8.5 to about 10.6 mol % of Al2O3, about 9.5 to about 12.8 mol % of K2O, about 0.5 to about 4.0 mol % of CaO, about 0 to about 3.0 mol % of TiO2, about 1.8 to about 4.0 mol % of Na2O, about 0.1 to about 6.0 mol % of Li2O, about 0 to about 1.0 mol % of MgO, about 0 to about 3.0 mol % of Nb2O5, and about 0 to about 3.0 mol % of B2O3. The leucite glass-ceramic is prepared by subjecting the glass components to a nucleation heat treatment, followed by a growth heat treatment. The leucite glass-ceramic may be used in the fabrication of a Dental restoration using various processes, and may be used in the construction of Dental restorations such as ceramic Dental inlays, crowns, veneers, bridges, veneering materials for zirconium oxide restoration substrates, alumina oxide restoration substrates, or metal restoration substrates.Type: ApplicationFiled: June 27, 2014Publication date: May 19, 2016Inventors: Antonios THEOCHAROPOULOS, Xiaohui CHEN, Natalia KARPUKHINA, Robert HILL, Mike CATTELL
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Publication number: 20160123926Abstract: A method of isolating nucleic acids from a biological material, comprises applying the biological material on a substrate comprising one or more cell lysis reagents impregnated therein; applying a fluid to the biological material applied on the substrate; extracting the nucleic acids from the biological material applied on the substrate; and collecting the extracted nucleic acids in a substantially intact form, wherein the collected nucleic acid has a molecular weight greater than or equal to 20 kb.Type: ApplicationFiled: September 25, 2015Publication date: May 5, 2016Inventors: John Richard Nelson, Christopher Michael Puleo, Erin Jean Finehout, Patrick McCoy Spooner, Kashan Ali Shaikh, Xiaohui Chen, Li Zhu
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Patent number: 9291672Abstract: A debug apparatus for debugging a chip under test with a plurality of pins is provided. The debug apparatus includes a processor for controlling the chip under test via a bridge device. The processor provides graphical data to indicate pin states of the chip under test when the chip under test is controlled by the processor.Type: GrantFiled: March 15, 2013Date of Patent: March 22, 2016Assignee: Nuvoton Technology CorporationInventors: Xiaohui Chen, Xiaocheng Shen
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Publication number: 20150337263Abstract: A method of processing an adipose tissue to collect adipose derived regenerative cells is provided, wherein the method comprises providing a vessel comprising a fluid jet mixer, introducing the adipose tissue into the vessel, introducing a buffer solution into the vessel; washing the adipose tissue using the fluid jet mixer; introducing an enzyme solution into the vessel; initiating jet mixing into the vessel comprising the adipose tissue, the enzyme solution, and the buffer solution using the fluid jet mixer to digest the adipose tissue to form a digestion product; phase-separating the digestion product into a digested buoyant fat layer and a non-buoyant aqueous layer; and collecting the non-buoyant aqueous layer comprising the adipose derived regenerative cells. A system of processing an adipose tissue to collect adipose derived regenerative cells is also provided.Type: ApplicationFiled: July 30, 2015Publication date: November 26, 2015Inventors: Zaeem Ashraf Khan, Aaron Joseph Dulgar-Tulloch, Stefan Rakuff, Philip Alexander Shoemaker, Erik Leeming Kvam, Xiaohui Chen, Jaydeep Roy
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Publication number: 20150259671Abstract: A device, a system, a cartridge and a method for isolating biomolecules from biological materials are provided. The device comprises a substrate; a reagent storage location; and a self-rupturing component comprising a fluid and a pressure source embedded therein, wherein the substrate, the reagent storage location and the self-rupturing component are operationally coupled to each other. A system is provided, wherein the system comprises an extraction matrix, an enclosed matrix housing comprising a biological sample inlet, one or more biomolecule extraction reagents to extract biomolecules and at least one pressure source embedded therein, a fluidic extraction circuit; and a controller for activating the embedded pressure source. A method of isolating nucleic acids from biological materials is also provided.Type: ApplicationFiled: July 31, 2012Publication date: September 17, 2015Applicant: GENERAL ELECTRIC COMPANYInventors: Christopher Michael Puleo, Ralf Lenigk, John Richard Nelson, Xiaohui Chen, Li Zhu, Erin Jean Finehout, Patrick McCoy Spooner
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Patent number: 9109198Abstract: A method of processing an adipose tissue to collect adipose derived regenerative cells is provided, wherein the method comprises providing a vessel comprising a fluid jet mixer; introducing the adipose tissue into the vessel; introducing a buffer solution into the vessel; washing the adipose tissue using the fluid jet mixer; introducing an enzyme solution into the vessel; initiating jet mixing into the vessel comprising the adipose tissue, the enzyme solution, and the buffer solution using the fluid jet mixer to digest the adipose tissue to form a digestion product; phase-separating the digestion product into a digested buoyant fat layer and a non-buoyant aqueous layer; and collecting the non-buoyant aqueous layer comprising the adipose derived regenerative cells. A system of processing an adipose tissue to collect adipose derived regenerative cells is also provided.Type: GrantFiled: April 29, 2011Date of Patent: August 18, 2015Assignee: General Electric CompanyInventors: Zaeem Ashraf Khan, Aaron Joseph Dulgar-Tulloch, Stefan Rakuff, Philip Alexander Shoemaker, Erik Leeming Kvam, Xiaohui Chen, Jaydeep Roy
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Patent number: 9103331Abstract: An electroosmotic pump comprises a plurality of membranes comprising one or more positive electroosmotic membranes and one or more negative electroosmotic membranes, a plurality of electrodes comprising cathodes and anodes, and a power source. Each of the positive electroosmotic membranes and negative electroosmotic membranes are disposed alternatively and wherein at least one of the cathodes is disposed on one side of one of the membranes and at least one of the anodes is disposed on other side of the membrane. At least one of the cathodes or anodes is disposed between a positive electroosmotic membrane and negative electroosmotic membrane.Type: GrantFiled: December 15, 2011Date of Patent: August 11, 2015Assignee: General Electric CompanyInventors: Christopher Michael Puleo, Christopher Fred Keimel, Xiaohui Chen, Ralf Lenigk, Craig Patrick Galligan, Todd Frederick Miller
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Publication number: 20150106436Abstract: A videoconferencing system in which multiple browsers are utilized to present content and control functions for a server based videoconference. The content of the videoconference (e.g., video and audio streams) is presented on a display device driven by a local computer running a browser. The local computer also runs a separate browser that presents control functions on a different display device (e.g., a touch screen). The system can be scaled to include additional monitors and browsers running on the local computer. A local server is provided on the local computer for facilitating communications among the locally running browsers. In this manner, the browsers can communicate with each other via the local server executing on the local computer. The need to send traffic to a remote server to effectuate the browser-to-browser communication is eliminated. This provides for reduced latency and lowers the demands on the remote server.Type: ApplicationFiled: December 16, 2014Publication date: April 16, 2015Applicant: Google Inc.Inventors: James Deyerle, Alan Savage, Xiaohui Chen, Christopher Lane, Antonio Petruzziello, William Shields
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Publication number: 20150094548Abstract: In accordance with one aspect of the present technique, a method is disclosed. The method includes applying a mechanical perturbation to a tissue region using a displacement device. The method further includes calculating a compression impedance of the tissue region in response to applying the mechanical perturbation. The method further includes retracting the displacement device and calculating a retraction impedance of the tissue region in response to retracting the displacement device. The method also includes determining a hydration level of the tissue region based on at least one of the compression impedance and the retraction impedances.Type: ApplicationFiled: September 27, 2013Publication date: April 2, 2015Applicant: General Electric CompanyInventors: James Enrico Sabatini, Jeffrey Michael Ashe, Xiaohui Chen, Tzu-Jen Kao
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Patent number: 8939294Abstract: A separation matrix comprises a porous surface layer; and a bulk porous support, wherein both the porous surface layer and the bulk porous support comprising a block copolymer. The block copolymer comprises A-B or A-B-A repeating units, wherein A and B at each occurrence are two different blocks of oligomer, or polymer. A structural unit of block A is derived from one or more atom transfer radical polymerization (ATRP)-active monomer or oligomer and a structural unit of block B is derived from a thermoplastic ATRP-active macro initiator. A poly dispersity index of the block copolymer is at least about 2.Type: GrantFiled: March 31, 2010Date of Patent: January 27, 2015Assignee: General Electric CompanyInventors: David Roger Moore, Hongyi Zhou, Matthew Jeremiah Misner, Xiaohui Chen, Lifeng Zhang, Daniel Joseph Brunelle, Minglin Ma
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Patent number: 8937637Abstract: A videoconferencing system in which multiple browsers are utilized to present content and control functions for a server based videoconference. The content of the videoconference (e.g., video and audio streams) is presented on a display device driven by a local computer running a browser. The local computer also runs a separate browser that presents control functions on a different display device (e.g., a touch screen). The system can be scaled to include additional monitors and browsers running on the local computer. A local server is provided on the local computer for facilitating communications among the locally running browsers. In this manner, the browsers can communicate with each other via the local server executing on the local computer. The need to send traffic to a remote server to effectuate the browser-to-browser communication is eliminated. This provides for reduced latency and lowers the demands on the remote server.Type: GrantFiled: July 26, 2012Date of Patent: January 20, 2015Assignee: Google Inc.Inventors: James Deyerle, Alan Savage, Xiaohui Chen, Christopher Lane, Antonio Petruzziello, William Shields
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Publication number: 20150002168Abstract: One system includes a pattern generator that generates one or more excitation patterns suitable for probing a hydration level of a tissue of a subject at one or more depths from a surface of the subject into an interrogation region. Each of the excitation patterns has a spatial sensitivity at one of the one or more predetermined depths. A data analysis module receives one or more measured responses of the subject at a plurality of electrodes to excitation applied by the plurality of electrodes based on the one or more excitation patterns and determines one or more hydration changes at the one or more depths within the subject based on the measured responses. Each of the measured responses corresponds to the one of the one or more predetermined depths for which the applied excitation pattern has spatial sensitivity.Type: ApplicationFiled: June 27, 2013Publication date: January 1, 2015Inventors: Tzu-Jen Kao, David Michael Davenport, Jeffrey Michael Ashe, Xiaohui Chen
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Publication number: 20140289839Abstract: Embodiments of the present invention disclose a resource control method and apparatus. A client sends an authorization request message to a content provider. The content provider sends an authorization response message to the client according to a user identifier carried in the authorization request message, where the authorization response message carries an authorized access token. The client sends a content request message to a storage server corresponding to the content provider, where the content request message carries an identifier of content requested by the client and the authorized access token. The client receives the content sent by the storage server according to the authorized access token. The present invention is applied to the field of network resource management.Type: ApplicationFiled: June 10, 2014Publication date: September 25, 2014Inventors: Xiaohui Chen, Hanyu Wei, Ruifeng Wang
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Publication number: 20140173370Abstract: A debug apparatus for debugging a chip under test with a plurality of pins is provided. The debug apparatus includes a processor for controlling the chip under test via a bridge device. The processor provides graphical data to indicate pin states of the chip under test when the chip under test is controlled by the processor.Type: ApplicationFiled: March 15, 2013Publication date: June 19, 2014Applicant: NUVOTON TECHNOLOGY CORPORATIONInventors: Xiaohui CHEN, Xiaocheng SHEN
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Publication number: 20140039177Abstract: A method of isolating nucleic acids from a biological material, comprises applying the biological material on a substrate comprising one or more cell lysis reagents impregnated therein; applying a fluid to the biological material applied on the substrate; extracting the nucleic acids from the biological material applied on the substrate; and collecting the extracted nucleic acids in a substantially intact form, wherein the collected nucleic acid has a molecular weight greater than or equal to 20 kb.Type: ApplicationFiled: August 30, 2012Publication date: February 6, 2014Applicant: GENERAL ELECTRIC COMPANYInventors: John Richard Nelson, Li Zhu, Erin Jean Finehout, Xiaohui Chen, Kashan Ali Shaikh, Christopher Michael Puleo, Patrick McCoy Spooner
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Publication number: 20140039172Abstract: A device, a system, and a method for isolating biomolecules from biological materials are provided. The device comprises a quartz-based solid phase extraction matrix comprising one or more reagents impregnated therein; and an electroosmotic pump (EOP) operationally coupled to the quartz-based solid phase extraction matrix to elute the nucleic acids, wherein the EOP comprises a plurality of electroosmotic membranes comprising one or more positive electroosmotic membranes and one or more negative electroosmotic membranes disposed alternatively and a plurality of electrodes comprising one or more cathodes and one or more anodes, wherein at least one cathode is disposed on one side of one of the membranes and at least one anode is disposed on another side of that membrane and at least one cathode or anode is disposed between a positive electroosmotic membrane and a negative electroosmotic membrane.Type: ApplicationFiled: August 30, 2012Publication date: February 6, 2014Applicant: GENERAL ELECTRIC COMPANYInventors: John Richard Nelson, Li Zhu, Xiaohui Chen, Christopher Michael Puleo, Patrick McCoy Spooner
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Publication number: 20140028784Abstract: A videoconferencing system in which multiple browsers are utilized to present content and control functions for a server based videoconference. The content of the videoconference (e.g., video and audio streams) is presented on a display device driven by a local computer running a browser. The local computer also runs a separate browser that presents control functions on a different display device (e.g., a touch screen). The system can be scaled to include additional monitors and browsers running on the local computer. A local server is provided on the local computer for facilitating communications among the locally running browsers. In this manner, the browsers can communicate with each other via the local server executing on the local computer. The need to send traffic to a remote server to effectuate the browser-to-browser communication is eliminated. This provides for reduced latency and lowers the demands on the remote server.Type: ApplicationFiled: July 26, 2012Publication date: January 30, 2014Applicant: GOOGLE INC.Inventors: James DEYERLE, Alan SAVAGE, Xiaohui CHEN, Christopher LANE, Antonio PETRUZZIELLO, William SHIELDS
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Publication number: 20130153425Abstract: An electroosmotic pump comprises a plurality of membranes comprising one or more positive electroosmotic membranes and one or more negative electroosmotic membranes, a plurality of electrodes comprising cathodes and anodes, and a power source. Each of the positive electroosmotic membranes and negative electroosmotic membranes are disposed alternatively and wherein at least one of the cathodes is disposed on one side of one of the membranes and at least one of the anodes is disposed on other side of the membrane. At least one of the cathodes or anodes is disposed between a positive electroosmotic membrane and negative electroosmotic membrane.Type: ApplicationFiled: December 15, 2011Publication date: June 20, 2013Applicant: GENERAL ELECTRIC COMPANYInventors: Christopher Michael Puleo, Christopher Fred Keimel, Xiaohui Chen, Ralf Lenigk, Craig Patrick Galligan, Todd Frederick Miller