Abstract: The present invention relates generally to compositions and methods for treating cancer and hypercortisolism. Provided herein are substituted steroidal derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of glucocorticoid receptors. Furthermore, the subject compounds and compositions are useful for the treatment of cancer.

Abstract: Provided is a length adjuster on a wearable device, comprising an arc-shaped shell and a length fine-adjustment mechanism, wherein a first connection rack, a second connection rack, a gear, and a button and a return spring of a gear shaft are provided in the arc-shaped shell; the first connection rack, the second connection rack and the gear are meshed with one another, the gear shaft is connected to a clockwork spring mechanism, the gear shaft and the length fine-adjustment mechanism are in a clutch connection, and the gear shaft and the length fine-adjustment mechanism may be in a clutch connection; and a unidirectional rotation-prevention structure is provided in the length fine-adjustment mechanism, and the unidirectional rotation-prevention structure allows the length fine-adjustment mechanism to drive the gear shaft to rotate in a rotation direction for enabling a clockwork spring to be stretched, and prevents the gear shaft from rotating in the direction opposite to the rotation direction.

Abstract: A UV sterilization device for a board-type kitchenware includes a base with a driving member being received therein and defining a first motor, a left work-board, a right work-board, with a receiving room being formed between the left and right work-boards for receiving the board-type kitchenware therein, and a UV sterilization module connected to the first motor, longitudinally arranged on the inside of the left and right work-boards and horizontally sliding relative to the left and right work-boards. The first motor is configured to drive the UV sterilization module to slide so as to sterilize the board-type kitchenware received in the receiving room. The present structure not only can have a good disinfection and bactericidal effect on the harmful bacteria, pathogenic bacteria and molds left on the kitchenware with a minimize disinfection time, but also can reciprocate sterilization of the board-type kitchenware to achieve all-round sterilization by simple operation.

Abstract: A method for migration of data is provided. The method includes triggering a rebuild of data according to a first migration mechanism from a first storage drive to a second storage drive. Monitoring space utilization associated with the second storage drive, and adaptively switching the migration of the data from the first migration mechanism to a second migration mechanism based on the monitoring.

Abstract: Techniques are disclosed for blur classification. The techniques utilize an image content feature map, a blur map, and an attention map, thereby combining low-level blur estimation with a high-level understanding of important image content in order to perform blur classification. The techniques allow for programmatically determining if blur exists in an image, and determining what type of blur it is (e.g., high blur, low blur, middle or neutral blur, or no blur). According to one example embodiment, if blur is detected, an estimate of spatially-varying blur amounts is performed and blur desirability is categorized in terms of image quality.

Abstract: An HFET includes a first and second semiconductor material. A first composite passivation layer includes a first insulation layer and a first passivation layer, and the first passivation layer is disposed between the first insulation layer and the second semiconductor material. The HFET includes a second passivation layer, where the first insulation layer is disposed between the first passivation layer and the second passivation layer. A gate dielectric is disposed between the second semiconductor material and the first passivation layer. A source electrode and a drain electrode are coupled to the second semiconductor material, and a gate electrode is disposed laterally between the source electrode and the drain electrode. A first gate field plate is disposed between the first passivation layer and the second passivation layer and electrically connected to the gate electrode, and a second gate field plate is disposed above first gate field plate.

Abstract: The present invention relates to a cosmetic composition and a cleaning and caring product comprising the same, use and application method of the cleaning and caring product. The cosmetic composition comprises: a polymerization product, which is obtained by reacting a system comprising the following components: an anionic polymer, an amphoteric polymer and water, the weight ratio of the anionic polymer to the amphoteric polymer is in the range from 1:100 to 100:1 and the total weight of the anionic polymer and the amphoteric polymer is no less than 0.1 wt %, based on that the amount of the composition is 100 wt %; an optional cationic polymer; an optional active ingredient; an optional additive; and an optional cosmetically acceptable medium.

Abstract: The present invention provides a drainage control device and a cleaning robot, the drainage control device includes a water tank body and a middle cover sealingly disposed on an upper portion of the water tank body; wherein the middle cover is provided with a water inlet, an air inlet, and a steering engine assembly engaged with the air inlet and configured to adjust an opening size of the air inlet to control an air intake amount, the water inlet is mounted with a sealing cover, and a lower portion of the water tank body is provided with at least one water outlet. The present invention precisely controls the air intake amount through the steering gear assembly and the air inlet, and can accurately control the water output under the action of the atmospheric pressure, which is very suitable for the occasion where the displacement needs precise control.

Abstract: Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: The present disclosure discloses a mobile terminal and a battery cover of mobile terminal, the battery cover of mobile terminal includes a main control circuit, a power management circuit, a touch circuit and an e-Ink; wherein the main control circuit, the power management circuit and the touch circuit are connected to the e-Ink respectively; the main control circuit and the power management circuit are connected to the mobile terminal respectively; the main control circuit is connected to the touch circuit; the power management circuit is configured to supply power to the e-Ink; the touch circuit is configured to receive a screen changing operation of the e-Ink; and the main control circuit is configured to receive data from the touch circuit, communicate with the mobile terminal and display contents of communication on the e-Ink.

Abstract: A folding chair having a side table, including a folding chair frame and a folding table frame that is foldably linked with the folding chair frame, a plurality of support connectors are provided on the upper end of the folding table frame, and the plurality of support connectors are in the same horizontal plane to support tabletop when the folding table frame is in an unfolded state. The independent folding chair frame and folding table frame are provided. A plurality of support connectors is provided on the upper end of the folding table frame so as to place tabletop. It is implemented by providing the side table and chair frame independently. The side table is provided with a relatively large size, which has relatively more items being placed. The folding chair frame and the folding table frame are formed in a folding linkage to achieve unified folding.

Abstract: Embodiments of the present disclosure relate to a sky editing system and related processes for sky editing. The sky editing system includes a composition detector to determine the composition of a target image. A sky search engine in the sky editing system is configured to find a reference image with similar composition with the target image. Subsequently, a sky editor replaces content of the sky in the target image with content of the sky in the reference image. As such, the sky editing system transforms the target image into a new image with a preferred sky background.

Abstract: A method for fluoroscopy energizes a radiation source to form a scout image on a detector and processes the scout image to determine and report a radiation field position with respect to a predetermined zone of the detector. The radiation source is energized for fluoroscopic imaging of a subject when the reported radiation field position is fully within the predetermined zone.

Abstract: A subset of humanized anti-PD-1 antibodies that inhibit binding of PD-L1 and PD-L2 to human PD-1. These binding proteins modulate the immune system through the manipulation of the PD-1 signaling pathway to treat immune dysfunctional disorders, including for example cancers.

Abstract: This invention discloses an ultrasonic probe, an ultrasonic imaging system and their detail usage for biopsy needle visualization enhancement. The invention adds new lateral element arrays in the elevation direction of a center element array of a conventional linear/curve linear array probe, and allows a clinician to control the lateral element arrays to be turned on or off manually, or by a system analysis unit through intelligent judgment. During imaging, when the lateral element arrays are turned on, they will substantially enlarge the effective range of an ultrasonic field created by this probe in a needle body searching mode, so that the needle body is more easily captured and displayed in an image. By turning off the lateral arrays after the needle body is captured, a high-resolution imaging mode is recovered, thus the image quality will still be good enough for conventional clinical usage.

Abstract: In implementations of object detection in images, object detectors are trained using heterogeneous training datasets. A first training dataset is used to train an image tagging network to determine an attention map of an input image for a target concept. A second training dataset is used to train a conditional detection network that accepts as conditional inputs the attention map and a word embedding of the target concept. Despite the conditional detection network being trained with a training dataset having a small number of seen classes (e.g., classes in a training dataset), it generalizes to novel, unseen classes by concept conditioning, since the target concept propagates through the conditional detection network via the conditional inputs, thus influencing classification and region proposal. Hence, classes of objects that can be detected are expanded, without the need to scale training databases to include additional classes.

Abstract: A display panel circuit structure is provided. The display panel circuit structure includes: a display area and an output bonding area located on a side of the display area. The output bonding area includes: a plurality of first bonding pads arranged in parallel at intervals, and a plurality of first connecting lines between corresponding first bonding pads of the first bonding pads. Each of the first bonding pads includes: a first bottom pad, a first middle pad, and a first top pad.

Abstract: A stove using biomass pellets as fuels is disclosed herein, comprising a stove body that comprises a firebox, at least one hopper, and a feed tube, wherein the at least one hopper is connected to the firebox via the feed tube, and fuels contained inside the at least one hopper can enter the firebox along the feed tube under gravity. The stove has a simple structure and removes any mechanically or electrically controlled feeding system by feeding the firebox using gravity of the fuels, therefore lowers the cost.

Abstract: In some embodiments, a method trains a first prediction network to predict similarity between images in videos. The training uses boundaries detected in the videos to train the prediction network to predict images in a same scene to have similar feature descriptors. The first prediction network generates feature descriptors that describe library images from videos in a video library offered to users of a video delivery service. A search image is received and the prediction network predicts one or more library images for one or more videos that are predicted to be similar to the received image. The one or more library images for the one or more videos are provided as a search result.

Abstract: In implementations of object detection in images, object detectors are trained using heterogeneous training datasets. A first training dataset is used to train an image tagging network to determine an attention map of an input image for a target concept. A second training dataset is used to train a conditional detection network that accepts as conditional inputs the attention map and a word embedding of the target concept. Despite the conditional detection network being trained with a training dataset having a small number of seen classes (e.g., classes in a training dataset), it generalizes to novel, unseen classes by concept conditioning, since the target concept propagates through the conditional detection network via the conditional inputs, thus influencing classification and region proposal. Hence, classes of objects that can be detected are expanded, without the need to scale training databases to include additional classes.