Abstract: A main drive control method for glass factories, comprising the following steps: (a) providing a first circuit breaker and a second circuit breaker on a power supply loop of an electrical motor, wherein one end thereof is respectively connected to two main drive electrical motors; (b) enabling the first circuit breaker to be connected to a municipal power supply and the second circuit breaker to be connected to a UPS power supply; and (c) enabling the first circuit breaker and the second circuit breaker to be interlocked via a mechanical interlocking mechanism, so that only one of the circuit breakers can be switched on during a normal operation. The main drive control method for glass factories solves the problem that the rotation speed of a main drive electrical motor is incorrect due to the interference on a signal.

Abstract: Methods and apparatuses are disclosed for secure network communications. An exemplary method may include sending a handshake request message to a server. The handshake request message contains a first random number encrypted by using a first public key and first service request data encrypted by using the first public key. The method may also include receiving a handshake response message replied from the server. The handshake response message contains the first service response data encrypted by using the first random number and a second random number encrypted by using the first random number. The method may further include decrypting the handshake response message by using the first random number to obtain the first service response data and the second random number. In addition, the method may include calculating a session key used in a session with the server in accordance with the first random number and the second random number.

Abstract: A main drive control method for glass factories, comprising the following steps: (a) providing a first circuit breaker and a second circuit breaker on a power supply loop of an electrical motor, wherein one end thereof is respectively connected to two main drive electrical motors; (b) enabling the first circuit breaker to be connected to a municipal power supply and the second circuit breaker to be connected to a UPS power supply; and (c) enabling the first circuit breaker and the second circuit breaker to be interlocked via a mechanical interlocking mechanism, so that only one of the circuit breakers can be switched on during a normal operation. The main drive control method for glass factories solves the problem that the rotation speed of a main drive electrical motor is incorrect due to the interference on a signal.

Abstract: Methods and apparatuses are disclosed for secure network communications. An exemplary method may include sending a handshake request message to a server. The handshake request message contains a first random number encrypted by using a first public key and first service request data encrypted by using the first public key. The method may also include receiving a handshake response message replied from the server. The handshake response message contains the first service response data encrypted by using the first random number and a second random number encrypted by using the first random number. The method may further include decrypting the handshake response message by using the first random number to obtain the first service response data and the second random number. In addition, the method may include calculating a session key used in a session with the server in accordance with the first random number and the second random number.

Abstract: The present disclosure provides novel methods for treating cancer and conditions regulatable by a transcription factor and/or cofactor using specific compounds, as well as compositions, and pharmaceutical formulations. In certain embodiments, the compounds are transcription factor modulators.

Abstract: Amide derivatives of aniline-related compounds are disclosed, including salts thereof, and compositions, preparations and uses thereof. In certain embodiments, the amide derivatives and/or salts thereof show higher solubility in water compared to the corresponding parent aniline-related compounds.

Abstract: The present disclosure provides novel compounds capable of functioning as transcription factor modulators, as well as compositions, pharmaceutical formulations, and kits. Also provided are methods of treating a condition regulatable by a transcription factor and/or cofactor using the compounds, compositions, pharmaceutical formulations, and kits provided herein.

Abstract: Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds.

Abstract: The present disclosure provides novel compounds capable of functioning as transcription factor modulators, as well as compositions, pharmaceutical formulations, and kits. Also provided are methods of treating a condition regulatable by a transcription factor and/or cofactor using the compounds, compositions, pharmaceutical formulations, and kits provided herein.

Abstract: The present disclosure provides novel methods for treating cancer and conditions regulatable by a transcription factor and/or cofactor using specific compounds, as well as compositions, and pharmaceutical formulations. In certain embodiments, the compounds are transcription factor modulators.

Abstract: Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds.

Abstract: Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds.

Abstract: Three-dimensional structure of APOBEC-2 and other structure models of APOBEC proteins obtained by computer modeling that bear similarity with a root-mean-square deviation (RMSD) of 2.0 with the APOBEC-2 monomer, dimer or tetramer. Uses of the three-dimensional structure of APOBEC-2 and models of APOBEC proteins particularly for structure-based drug design of compounds, peptides or mutant APOBEC proteins designed to treat Hyper-IgM-2 Syndrome, B cell lymphomas and lentivirus infections, particularly the human immunodeficiency virus (HIV) infection. Methods for identifying a compound that binds to any fragment of an APOBEC protein.

Abstract: A low-cost sine-wave drive for a 3-phase permanent magnet synchronous AC machines (PMSM) in open-loop control is based on the measurements of two linear Hall sensors. The two Hall sensors are excited by a magnetic ring with the same pole number as the PMSM rotor magnet and sinusoidal flux distributions. The output signals of the Hall sensors are unified through a two-phase-type phase-lock-loop in order to reduce the impact of the sensor mounting non-uniformity during mass production. The peak torque and speed of motor is simply controlled by adjusting the amplitude of pulse-width-modulation carrier. Smooth torque control is achieved due to sinusoidal 3-phase currents. Such a simple sine-wave drive can be achieved with or without the assistance of a micro-controller unit (MCU). No current sensor is required for the motor phase current detection. This motor can be used in industrial applications where there is no strict requirement on torque response and constant speed control of PMSM machines.

Abstract: Structure and methods associated with the three-dimensional structure of G40P helicase and other structure models of any DnaB-like helicase obtained by computer modeling that bears similarity with a root-mean-square deviation (RMSD) of 2.0 with at least one of the three domain structures (N-globe, alpha-hairpin and the C-terminal ATPase domains). In one embodiment, a method for identifying a compound that binds to any fragment of a G40P protein is provided. The method including obtaining the three dimensional structure of the G40P hexamer whose sequence consists of SEQ ID NO:1 and identifying or designing one or more compounds that bind, mimic, enhance, disrupt, or compete with the G40P protein whose sequence consists of SEQ ID NO:1 or interactions of the G40P protein with its ligands based on the three dimensional structure of the G40P hexamer whose sequence consists of SEQ ID NO:1.

Abstract: Three-dimensional structure of APOBEC-2 and other structure models of APOBEC proteins obtained by computer modeling that bear similarity with a root-mean-square deviation (RMSD) of 2.0 with the APOBEC-2 monomer, dimer or tetramer. Uses of the three-dimensional structure of APOBEC-2 and models of APOBEC proteins particularly for structure-based drug design of compounds, peptides or mutant APOBEC proteins designed to treat Hyper-IgM-2 Syndrome, B cell lymphomas and lentivirus infections, particularly the human immunodeficiency virus (HIV) infection. Methods for identifying a compound that binds to any fragment of an APOBEC protein.

Abstract: Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds.

Abstract: Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds.

Abstract: A low-cost sine-wave drive for a 3-phase permanent magnet synchronous AC machines (PMSM) in open-loop control is based on the measurements of two linear Hall sensors. The two Hall sensors are excited by a magnetic ring with the same pole number as the PMSM rotor magnet and sinusoidal flux distributions. The output signals of the Hall sensors are unified through a two-phase-type phase-lock-loop in order to reduce the impact of the sensor mounting non-uniformity during mass production. The peak torque and speed of motor is simply controlled by adjusting the amplitude of pulse-width-modulation carrier. Smooth torque control is achieved due to sinusoidal 3-phase currents. Such a simple sine-wave drive can be achieved with or without the assistance of a micro-controller unit (MCU). No current sensor is required for the motor phase current detection. This motor can be used in industrial applications where there is no strict requirement on torque response and constant speed control of PMSM machines.

Abstract: Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds.