Patents by Inventor Xiaojiang Chen

Xiaojiang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Three-dimensional structure of complement receptor type 2 and uses thereof
    Publication number: 20040005538
    Abstract: Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds.
    Type: Application
    Filed: April 11, 2001
    Publication date: January 8, 2004
    Inventors: Xiaojiang Chen, Vernon Michael Holers
  • Compositions, preparations and uses of human papillomavirus L1 protein
    Publication number: 20030118609
    Abstract: Large quantities of soluble multimers of human papillomavirus L1 proteins can be produced in bacterial expression systems and used as therapeutic and diagnostic tools. L1 multimers can be used in immunogenic vaccine compositions, as diagnostic reagents, and as tools for mapping cell surface receptor interactions.
    Type: Application
    Filed: November 21, 2002
    Publication date: June 26, 2003
    Inventors: Stephen C. Harrison, Xiaojiang Chen
  • Vaccine compositions for human papillomavirus
    Patent number: 6551597
    Abstract: Large quantities of soluble multimers of human papillomavirus L1 proteins can be produced in bacterial expression systems and used as therapeutic and diagnostic tools. L1 multimers can be used in immunogenic vaccine compositions, as diagnostic reagents, and as tools for mapping cell surface receptor interactions.
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: April 22, 2003
    Assignee: President & Fellows of Harvard College
    Inventors: Stephen Harrison, Xiaojiang Chen