Abstract: An accommodating cylinder, a touch pen assembly, and a protective case are provided. The accommodating cylinder includes a cylinder body, a first magnetic member, a second magnetic member and a pen base. The cylinder body has an accommodating cavity. The first magnetic member is configured to generate a first magnetic field, and is arranged in the accommodating cavity. At least one of the first magnetic member and the second magnetic member is a coil, and the second magnetic member is arranged in the accommodating cavity and movable between a retracted position and an extended position. The pen base is connected with the second magnetic member. The second magnetic member is configured to move relative to the first magnetic member from the retracted position to the extended position, and to drive the pen base to move from an inserted position to a pop-up position in a first power-on state.

Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.

Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent.

Abstract: Microneedle arrays for introducing an active ingredient through a skin surface of a subject can include a base layer, a plurality of microneedles projecting from the base layer, and an active ingredient. Each of the microneedles comprises an elongate body having a proximal portion and a distal portion, in which the proximal portion is attached to the base layer. Each of the microneedles comprises at least one dissolvable polymer. The active ingredient is incorporated in the elongate body, and the active ingredient is present only in the distal portion and at least internally in the distal portion.

Abstract: The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.

Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions made with a di-amine or multiamine crosslinker in the presence of a carbodiimide coupling agent.

Abstract: Microneedle arrays for introducing an active ingredient through a skin surface of a subject can include a base layer, a plurality of microneedles projecting from the base layer, and an active ingredient. Each of the microneedles comprises an elongate body having a proximal portion and a distal portion, in which the proximal portion is attached to the base layer. Each of the microneedles comprises at least one dissolvable polymer. The active ingredient is incorporated in the elongate body, and the active ingredient is present only in the distal portion and at least internally in the distal portion.

Abstract: Provided are injectable, hyaluronic acid-based dermal filler compositions including conjugated vitamin C derivatives. The compositions provide for extended release of active vitamin C into tissue, promoting collagenesis and other benefits to skin.

Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.

Abstract: Dermal filler compositions can comprise hyaluronic acid and a conjugated vitamin C derivative. The compositions can provide for extended release of active vitamin C into tissue, which can promote collagenesis and other benefits to skin.

Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.

Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.

Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.

Abstract: A built-in S-typed array eddy current testing probe and a method for detecting defects of a tubular structure are provided. The probe includes an exciting coil part and a plurality of pick-up coil parts, wherein: the exciting coil part includes multiple bundles of exciting coil wires helically wound on a columnar coil former with a same interval; two bundles of exciting coil wires with an interval of 180° are connected at an end of the columnar coil former, actually being a same group of exciting coil wire bundles; each pick-up coil part consists of two rows of pancake coils; each four pancake coils which are closely arranged in a square shape form one differential eddy current testing pick-up unit; a final output signal is a result of additions between signals of opposite pancake coils and subtractions between signals of adjacent pancake coils in each differential eddy current testing pick-up unit.

Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.

Abstract: A built-in S-typed array eddy current testing probe and a method for detecting defects of a tubular structure are provided.

Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.

Abstract: The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.

Abstract: Dermal filler compositions presented herein can contain a vitamin that is conjugated to a hyaluronic acid.

Abstract: Provided are injectable, hyaluronic acid-based hydrogel compositions including conjugated vitamins.