Patents by Inventor Xiaojing Wang

Xiaojing Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250230147
    Abstract: Various lactam compound that binds Cbl-B, many of which are selective for Cbl-B over C-Cbl, and methods of making and using the same.
    Type: Application
    Filed: November 6, 2024
    Publication date: July 17, 2025
    Applicant: Genentech, Inc.
    Inventors: Jun Liang, Araz Jakalian, Michael John Lambrecht, Robin Larouche-Gauthier, Malcolm Huestis, Man Un Ung, Xiaojing Wang, Arun Yadav, Jason Robert Zbieg, Fabio Broccatelli
  • Publication number: 20250177318
    Abstract: Provided are functional segregated telodendrimers having, for example, two or three functional segments. The telodendrimers can aggregate to form nanocarriers. The telodendrimers can have one or more tetracycline drugs (such as CMT-3) physically bound thereto that release under physiological conditions. Such nanocarriers with loaded CMT-3 disperse stably in aqueous solution and may be used in treating inflammatory disease through local or systemic administration. Also provided are methods of treating acute respiratory distress syndrome (ARDS) and/or CARDS in a subject in need thereof, including: administering a therapeutically effective amount of CMT-3 and one or more nonantimicrobial host-modulators directly to the lungs of the patient. In embodiments, CMT-3 is administered to the lungs in an aerosolized formulation. In embodiments, subsequent to CMT-3 administration, one or more non-antimicrobial host-modulators directly to the lungs of the patient.
    Type: Application
    Filed: January 3, 2023
    Publication date: June 5, 2025
    Inventors: Juntao LUO, Robert COONEY, Qinghe MENG, Xiaojing WANG, Dandan GUO, Gary NIEMAN, Lorne GOLUB, Francis JOHNSON, Hsi-Ming LEE
  • Publication number: 20250114338
    Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: December 18, 2024
    Publication date: April 10, 2025
    Applicant: Genentech, Inc.
    Inventors: Sharada Labadie, Jun Liang, Daniel Fred Ortwine, Xiaojing Wang, Jason Zbieg, Birong Zhang, Simon Charles Goodacre, Nicholas Charles Ray, Jun Li
  • Patent number: 12233052
    Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: February 25, 2025
    Assignee: Genentech, Inc.
    Inventors: Sharada Labadie, Jun Liang, Daniel Fred Ortwine, Xiaojing Wang, Jason Zbieg, Birong Zhang, Simon Charles Goodacre, Nicholas Charles Ray, Jun Li
  • Patent number: 12187709
    Abstract: A compound, of formula (I): suitable for treating a cancer wherein the cancer is susceptible to inhibition of Cbl-B.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: January 7, 2025
    Assignee: Genentech, Inc.
    Inventors: Malcolm Huestis, Michael John Lambrecht, Jun Liang, Man Un Ung, Xiaojing Wang, Jason Robert Zbieg, Bing-Yan Zhu, Lisa Marie Barton, Fabio Broccatelli, Georgette Marie Castanedo, Araz Jakalian, Robin Larouche-Gauthier, Arun Yadav
  • Publication number: 20240300927
    Abstract: Various amide compounds that bind Cbl-B, including those that are selective for C-Cbl, and methods of making and using the same.
    Type: Application
    Filed: February 3, 2022
    Publication date: September 12, 2024
    Applicant: Genentech, Inc.
    Inventors: Jun Liang, Araz Jakalian, Michael John Lambrecht, Robin Larouche-Gauthier, Malcolm Huestis, Man Un Ung, Xiaojing Wang, Arun Yadav, Jason Robert Zbieg, Fabio Broccatelli
  • Publication number: 20240218316
    Abstract: A Bacillus velezensis (B. velezensis) strain bred through ultrasound-assisted adaptive evolution and use thereof are provided. In the present disclosure, a B. velezensis strain (B. velezensis CICC 23571) is used as a starting strain, and an ultrasound-assisted adaptive evolution process is performed, where a proportion of organic nitrogen in a medium is continuously reduced and proportions of inorganic nitrogen and a sugar source are increased to obtain a B. velezensis mutant strain with a high polypeptide yield. Different metabolic pathways in the mutant strain are enhanced, such that the mutant strain can efficiently convert inorganic nitrogen into organic nitrogen or reduce the deaminization of organic nitrogen, and finally a yield of polypeptides is greatly increased.
    Type: Application
    Filed: December 16, 2021
    Publication date: July 4, 2024
    Applicant: JIANGSU UNIVERSITY
    Inventors: Siyu RUAN, Haile MA, Yunliang LI, Yaoyong JI, Xiaojing WANG, Anqi ZHOU, Pengfei XIE, Xiaoshuang LIU
  • Publication number: 20230414982
    Abstract: A lithium battery module including a housing, a cover, at least one lithium battery cell and a fire retardant material is provided. The cover covers the housing. The housing and the cover form an accommodating space. The lithium battery cell is disposed in the accommodating space. The fire retardant material is filled in the accommodating space.
    Type: Application
    Filed: June 20, 2023
    Publication date: December 28, 2023
    Applicants: Maxim Nature Green Energy Solutions, Ltd., LiWatt X Incorporation
    Inventor: Xiaojing Wang
  • Publication number: 20230391941
    Abstract: A polymer having a dispersing function, a preparation method therefor and use thereof as a cement dispersant are provided. The polymer has a structural unit (a), a structural unit (b) and a structural unit (c). The structural unit (a) is provided by an unsaturated polyether, the structural unit (b) is provided by an unsaturated acid and/or a salt thereof and/or an anhydride thereof, and the structural unit (c) is provided by a silane and/or siloxane having a polymerizable group and no less than five carbon atoms. The molar ratio of the structural unit (a), the structural unit (b) and the structural unit (c) is 1:(1-20):(0.01-0.5); and the polymer has a weight average molecular weight of 20,000-90,000 g/mol.
    Type: Application
    Filed: August 13, 2021
    Publication date: December 7, 2023
    Inventors: Xia MIAO, Shiming ZHOU, Haoguang WEI, Guangguo YANG, Lishuang WANG, Qichun WANG, Mu WANG, Xiaojing WANG, Min ZENG, Jian LIU, Xiaojiang LI, Xuepeng WU, Haoya LIU
  • Publication number: 20230381155
    Abstract: Provided herein are combination therapies comprising GDC-9545 and GDC-0077 for treating locally advanced breast cancer or metastatic breast cancer.
    Type: Application
    Filed: August 15, 2023
    Publication date: November 30, 2023
    Applicant: Genentech, Inc.
    Inventors: Ciara METCALFE, Xiaojing WANG, Wei ZHOU
  • Publication number: 20230381154
    Abstract: Provided herein are combination therapies comprising GDC-9545 and abemaciclib or ribociclib for treating locally advanced breast cancer or metastatic breast cancer.
    Type: Application
    Filed: August 15, 2023
    Publication date: November 30, 2023
    Applicant: Genentech, Inc.
    Inventors: Ciara METCALFE, Pablo Diego PEREZ-MORENO, Xiaojing WANG
  • Publication number: 20230281563
    Abstract: Managing and applying human resources data comprising aggregating employee transaction data for an organization. A number of human resources-related attributes are evaluated across heterogeneous transaction data. The employee transaction data is classified via statistical machine learning into a number of normalized codes according to the human resources-related attributes, a user interface is presented to adjust a number of organizational operating procedures according to the normalized codes.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 7, 2023
    Applicant: ADP, Inc.
    Inventors: Min Xiao, Lei Xia, Manish Karanjavkar, Dmitry Tolstonogov, Xiaojing Wang
  • Publication number: 20230212153
    Abstract: A compound, of formula (I): suitable for treating a cancer wherein the cancer is susceptible to inhibition of Cbl-B.
    Type: Application
    Filed: November 4, 2022
    Publication date: July 6, 2023
    Applicant: Genentech, Inc.
    Inventors: Malcolm HUESTIS, Michael John LAMBRECHT, Jun LIANG, Man Un UNG, Xiaojing WANG, Jason Robert ZBIEG, Bing-Yan Zhu, Lisa Marie BARTON, Fabio BROCCATELLI, Georgette Marie CASTANEDO, Araz JAKALIAN, Robin LAROUCHE-GAUTHIER, Arun YADAV
  • Publication number: 20230079990
    Abstract: Various lactam compound that binds Cbl-B, many of which are selective for Cbl-B over C-Cbl, and methods of making and using the same.
    Type: Application
    Filed: February 3, 2022
    Publication date: March 16, 2023
    Applicant: Genentech, Inc.
    Inventors: Jun LIANG, Araz JAKALIAN, Michael John LAMBRECHT, Robin LAROUCHE-GAUTHIER, Malcolm HUESTIS, Man Un UNG, Xiaojing WANG, Arun YADAV, Jason Robert ZBIEG, Fabio BROCCATELLI
  • Publication number: 20230045776
    Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: February 25, 2021
    Publication date: February 9, 2023
    Applicant: Genentech, Inc.
    Inventors: Sharada Labadie, Jun Liang, Daniel Fred Ortwine, Xiaojing Wang, Jason Zbieg, Birong Zhang, Simon Charles Goodacre, Nicholas Charles Ray, Jun Li, Tommy Lai, Jiangpeng Liao, Zhiguo Liu, John Wai, Tao Wang
  • Patent number: 11495163
    Abstract: The present disclosure provides a grayscale compensation method, a gray-scale compensation assembly, and a liquid crystal display device. The gray-scale compensation method includes: detecting a display region for compensation in the liquid crystal display screen that needs grayscale compensation under a reserved liquid crystal response time; acquiring a grayscale conversion timetable of the liquid crystal display screen, and obtaining a limit value of conversion time of the liquid crystal display screen according to the grayscale conversion timetable; acquiring a compensation grayscale lookup table of the display region for compensation; comparing the reserved liquid crystal response time and the limit value of conversion time to obtain a time comparison result; performing grayscale compensation on the display region according to the time comparison result, the grayscale conversion timetable and the compensation grayscale lookup table.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: November 8, 2022
    Assignees: Beijing BOE Optoelectronics Technology Co., Ltd., BEIJING BOE TECHNOLOGY
    Inventors: Xiaojing Wang, Hao Zhang, Wenhong Tian, Zijiao Xue, Nan Han, Shuaishuai Xu, Xinjie Huang
  • Publication number: 20220180793
    Abstract: The present disclosure provides a grayscale compensation method, a grayscale compensation assembly, and a liquid crystal display device. The grayscale compensation method includes: detecting a display region for compensation in the liquid crystal display screen that needs grayscale compensation under a reserved liquid crystal response time; acquiring a grayscale conversion timetable of the liquid crystal display screen, and obtaining a limit value of conversion time of the liquid crystal display screen according to the grayscale conversion timetable; acquiring a compensation grayscale lookup table of the display region for compensation; comparing the reserved liquid crystal response time and the limit value of conversion time to obtain a time comparison result; performing grayscale compensation on the display region according to the time comparison result, the grayscale conversion timetable and the compensation grayscale lookup table.
    Type: Application
    Filed: December 3, 2021
    Publication date: June 9, 2022
    Inventors: Xiaojing WANG, Hao ZHANG, Wenhong TIAN, Zijiao XUE, Nan HAN, Shuaishuai XU, Xinjie HUANG
  • Patent number: 11276363
    Abstract: A display driving control circuit, a display panel, and a driving control method are disclosed. A driving control sub-circuit in the display driving control circuit includes a first data selection sub-circuit, a second data selection sub-circuit, a third data selection sub-circuit, and a fourth data selection circuit. The first data selection sub-circuit, the second data selection sub-circuit, the third data selection sub-circuit, and the fourth data selection circuit are electrically connected to a first selection signal line respectively. The first data selection sub-circuit and the third data selection sub-circuit are electrically connected to a first data channel signal line, and the second data selection sub-circuit and the fourth data selection sub-circuit are electrically connected to a second data channel signal line.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: March 15, 2022
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Yafei Li, Zijiao Xue, Lukang Li, Xiaojing Wang, Xin Duan, Lingyun Shi, Xiurong Wang
  • Patent number: D1007407
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: December 12, 2023
    Inventors: Xu Wang, Xiaojing Wang, Xueji Xu, Yongqiang Xu, Song Su
  • Patent number: D1075202
    Type: Grant
    Filed: December 9, 2024
    Date of Patent: May 13, 2025
    Inventor: Xiaojing Wang