Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: Embodiments of the present disclosure provide a method for driving a display panel, a driving device for driving a display panel and a display device. The display panel includes a first display region and a second display region each including first color sub-pixel units. The method includes obtaining a respective target grayscale of each of the first color sub-pixel units, obtaining a respective first gamma voltage of each of the first color sub-pixel units in the first display region based on the respective target grayscale, and providing the respective first gamma voltage to each of the first color sub-pixel units in the first display region, and obtaining a respective second gamma voltage of the first color sub-pixel unit in the second display region based on the respective target grayscale, and providing the respective second gamma voltage to each of the first color sub-pixel units in the second display region.

Abstract: A predictive benchmarking of job wages is provided. Wage data is collected from a number of sources and preprocessed, wherein the wage data comprises a number of dimensions. A wide linear part of a wide-and-deep model is trained to emulate benchmarks and to memorize exceptions and co-occurrence of dimensions in the wage data. A deep part of the wide-and-deep model is concurrently trained to generalize rules for wage predictions across employment sectors based on relationships between dimensions. When a user request is received a number of wage benchmarks are forecast by summing linear coefficients produced by the wide linear part with nonlinear coefficients produced by the deep part according to parameters in a user request, and the wage benchmark forecasts are displayed.

Abstract: A method and apparatus for normalizing data. A computer system receives category data for a first code from a first client of a plurality of clients. The computer system also generates a category rule based on the category data. The computer system also assigns a category to a second code of a second client of the plurality of clients using the category rule. The category data is generated using input from the first client. Assigning the category to the second code of the second client comprises selecting the category rule to use to assign the category to the second code from a plurality of category rules.

Abstract: Managing and applying human resources data comprising aggregating employee transaction data for an organization. A number of human resources-related attributes are evaluated across heterogeneous transaction data. The employee transaction data is classified via statistical machine learning into a number of normalized codes according to the human resources-related attributes, a user interface is presented to adjust a number of organizational operating procedures according to the normalized codes.

Abstract: A display driving control circuit, a display panel, and a driving control method are disclosed. A driving control sub-circuit in the display driving control circuit includes a first data selection sub-circuit, a second data selection sub-circuit, a third data selection sub-circuit, and a fourth data selection circuit. The first data selection sub-circuit, the second data selection sub-circuit, the third data selection sub-circuit, and the fourth data selection circuit are electrically connected to a first selection signal line respectively. The first data selection sub-circuit and the third data selection sub-circuit are electrically connected to a first data channel signal line, and the second data selection sub-circuit and the fourth data selection sub-circuit are electrically connected to a second data channel signal line.

Abstract: Described herein are heteroaryl compounds with estrogen receptor modulation activity or function having the Formula I, II, and III structures: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I, II, and III compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: A method and system for analyzing employee retention across an enterprise based on commuter modeling is disclosed. The method can be implemented in a computer system which includes: mapping longitudinal and latitudinal coordinates of address information of a plurality of employees and a work location onto a map, which shows a predefined geographic location encompassing the work location surrounded by the longitudinal and latitudinal coordinates of the address information; obtaining calculated analytics data of employee turnover rate for the plurality of employees based on a commute distance from the work location to each of the longitudinal and latitudinal coordinates of the plurality of employees; and graphically overlaying the analytics data of the turnover rate for the plurality of employees onto the map to show employee turnover rate for different segments of the map.

Abstract: Described herein are heteroaryl compounds with estrogen receptor modulation activity or function having the Formula I, II, and III structures: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I, II, and III compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: An air-conditioner (10) is provided, including a casing (12), an evaporator (14), a front panel (16) and a temperature sensor (18). The casing (12) has an air inlet (120) and an air outlet (122). The evaporator (14) is arranged in the casing (12). The front panel (16) is arranged in front of the casing (12). The temperature sensor (18) is disposed to a back of the front panel (16) and is used for sensing an ambient temperature.

Abstract: A method and system for analyzing employee retention across an enterprise based on commuter modeling is disclosed. The method can be implemented in a computer system which includes: mapping longitudinal and latitudinal coordinates of address information of a plurality of employees and a work location onto a map, which shows a predefined geographic location encompassing the work location surrounded by the longitudinal and latitudinal coordinates of the address information; obtaining calculated analytics data of employee turnover rate for the plurality of employees based on a commute distance from the work location to each of the longitudinal and latitudinal coordinates of the plurality of employees; and graphically overlaying the analytics data of the turnover rate for the plurality of employees onto the map to show employee turnover rate for different segments of the map.

Abstract: Described herein are tetrahydronaphthalene compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: An image processing apparatus according to an embodiment includes a scanning protocol creation unit, an image acquisition unit, a post-processing unit, and a storage unit. The scanning protocol creation unit creates a scanning protocol for a particular part of body of an object. The image acquisition unit acquires source image data by scanning the particular part using an imaging device according to scanning parameters in the scanning protocol. The post-processing unit performs post-processing on the source image data according to post-processing parameters in the scanning protocol to obtain processed image data. The storage unit stores the scanning protocol, or store the source image data and the processed image data or index identifiers thereof in association with parameters related to the scanning protocol as single job data of the object. The scanning protocol includes the scanning and the post-processing parameters, and information related to the imaging device and the post-processing unit.

Abstract: Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: A method, a computer system, and a computer program product for digitally presenting a potentially competitive resource allocation for an organization. A computer system identifies employee data for a set of employees. The computer system determines a corresponding business function of a set of business functions for each employee of the set of employees by applying a normalized business function model to the employee data. The computer system determines an aggregate allocation for each business function based on a cumulative compensation of a subset of the set of employees in the corresponding business function. The computer system determines a resource distribution for the organization based on the aggregate allocations for each of the set of business functions. The computer system compares the resource distribution for the organization to a set of benchmark distributions to determine the competitive resource allocation for the organization.

Abstract: A method, computer system, and computer program product for determining job levels of an employee within an organization. A computer system identifies employee data for the employee. The computer system determines whether the employee is a manager or a non-manager based on the employee data for the employee. The computer system applies a manager employee level model to determine a manager job level of the employee in response to determining that the employee is a manager. The computer system applies a non-manager employee level model to determine a non-manager job level of the employee in response to determining that the employee is a non-manager.

Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.