Abstract: A cooking appliance includes a body defining a cooking cavity, and a mounting plate including pivotably coupled first and second panels and first and second locking features that are coupled to the first and second panels, respectively. The mounting plate is operable between a folded condition, wherein the second panel is pivoted relative to the first panel such that the mounting plate fits within the cooking cavity and the first locking feature is disengaged from the second locking feature, and an extended condition in which the mounting plate supports the body in a mounted condition of the cooking appliance. The first and second panels are generally parallel and the first locking feature is engaged with the second locking feature to maintain the mounting plate in the extended condition. The first and second locking features become engaged with each other upon movement of the mounting plate to the extended condition.

Abstract: A compound as a receptor-interacting protein (RIP) inhibitor, a preparation method therefor, and a use thereof, which relate to the field of chemical medicines, are provided. The compound is a compound as represented by formula (I), or a salt thereof, or a stereoisomer thereof, or a solvate thereof, or a prodrug thereof. The compound has good inhibitory activity on humanized RIP1 kinase, and can be used for preparing drugs for resisting inflammation, resisting tumors and the like.

Abstract: The present disclosure relates to novel methods for preparing rapamycin analog compounds, as well as to related intermediates useful in such methods.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat inflammatory bowel diseases, and processes and intermediates useful for preparing such compounds.

Abstract: The present invention relates to methods for treating patients with cancer, including patients with hematological malignancy, wherein the method comprises administering to the patient a therapeutically effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein.

Abstract: Disclosed are methods for treating Crohn's disease using a compound of the formula: or a pharmaceutically-acceptable salt thereof.

Abstract: The present disclosure provides processes for preparing a crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile and related intermediate compounds.

Abstract: A truck-mounted flipped automated operation equipment for a well workover, which includes a derrick and an operation platform. A guide rail is arranged on the front and back sides of the center of the operation platform, respectively, and a hydraulic clamp mechanism is arranged on the guide rail. An inner clamp frame support is arranged under the derrick, and a lifting cylinder is fixed on the left side of the derrick. The piston part of the lifting cylinder is provided with a fixed plate configured to rise and fall with the lifting cylinder, and the right side of the operation platform is hinged on the fixing plate. The fixed plate is further provided with a flipped cylinder. The cylinder barrel of the flipped cylinder is hinged on the fixed plate, and the piston part of the flipped cylinder is connected to the lower part of the operation platform.

Abstract: Systems and methods are provided for calculating authenticity of a human user. One method comprises receiving, via a network, an electronic request from a user device, instantiating a video connection with the user device; generating, using a database of questions, a first question; providing, via the network, the generated question to the user device; analyzing video and audio data received via the connection to extract facial expressions, calculating, using convolutional neural networks, first data and second data corresponding predetermined emotions based on facial expressions and audio data; generating candidate emotion data using the first and second data; determining whether the candidate emotion data predicts a predetermined emotion, and generating a second question to collect additional data for aggregating with the first and second data or determining the authenticity of the user and using the determined authenticity to decide on the user request.

Abstract: A support device for the rotation of a high-capacity and compact drill pipe storage unit of a seabed drilling rig in a lying state, including: a rack, a plurality of curved support frames, a plurality of lateral drill pipe stoppers and a plurality of annular fences. The curved support frames are provided parallelly and coaxially on a slideway of the rack. A separating plate is provided on each of the curved support frames. A curved support surface of each of the curved support frames is in contact with a circular edge surface of the corresponding separating plate. The annular fences are mounted on the rack. Each of the annular fences is provided with a first gap and a second gap. The first gap is provided corresponding to the lateral drill pipe stopper. The second gap is configured to allow the drill pipes enter and exit the drill pipe storage unit.

Abstract: The present invention relates to methods for treating patients with cancer, including patients with hematological malignancy, wherein the method comprises administering to the patient a therapeutically effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are as defined herein.

Abstract: Methods and systems for arranging hyperlinks on a graphical user-interface (GUI) of a computerized system include receiving, via the GUI, a user selection to display a plurality of hyperlinks, the hyperlinks corresponding to one or more nodes of a first set. The methods and systems further include determining, by a processor, a rank of each hyperlink in the plurality of hyperlinks. Determining a rank includes constructing a first bipartite graph between the one or more nodes of the first set and one or more nodes of a second set, the first set and the second set being mutually exclusive, wherein edges of the first bipartite graph are weighted according to a first criterium and constructing a second bipartite graph between the one or more nodes of the first set and the one or more nodes of the second set, wherein edges of the second bipartite graph are weighted according to a second criterium, different from the first criterium.

Abstract: The present disclosure provides processes for preparing a crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile and related intermediate compounds.

Abstract: Methods and systems for detecting fraudulent data points in a database of a computerized system include receiving, from a user device, a request for detecting one or more fraudulent data points in a database storing data points representing electronic transactions. The system constructs a feature vector fore each data point and k random vectors. After constructions, the system performs a combination of Locality Sensitive Hashing algorithm and Local Outlier Factor (LOF) algorithm on the constructed feature vectors and the constructed k random vectors to compute outlier scores for each data point. The system detects a fraudulent data point based on the outlier scores that indicate consistent degrees.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: Systems and methods are provided for calculating authenticity of a human user. One method comprises receiving, via a network, an electronic request from a user device, instantiating a video connection with the user device; generating, using a database of questions, a first question; providing, via the network, the generated question to the user device; analyzing video and audio data received via the connection to extract facial expressions, calculating, using convolutional neural networks, first data and second data corresponding predetermined emotions based on facial expressions and audio data; generating candidate emotion data using the first and second data; determining whether the candidate emotion data predicts a predetermined emotion, and generating a second question to collect additional data for aggregating with the first and second data or determining the authenticity of the user and using the determined authenticity to decide on the user request.

Abstract: There is provided a wireline coring recovery system of a seafloor drilling rig, including: a winch, a rope, a submersible tension sensor, a cover, a main shaft and a catcher. One end of the rope is wound on the winch, and the other end of the rope is connected to an upper end of the catcher after the rope passes over a first pulley provided below the submersible tension sensor and then through a tapered hole on the cover. The catcher is provided in a center hole of the main shaft. The present application further provides a method of using the wireline coring recovery system. By the cooperation of the compression rod skewed teeth, the first rotating core skewed teeth, the second rotating core skewed teeth and the compression spring, the inner core barrel is readily recovered or released.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat inflammatory bowel diseases, and processes and intermediates useful for preparing such compounds.

Abstract: Systems and methods are provided for calculating authenticity of a human user. One method comprises receiving, via a network, an electronic request from a user device, instantiating a video connection with the user device; generating, using a database of questions, a first question; providing, via the network, the generated question to the user device; analyzing video and audio data received via the connection to extract facial expressions, calculating, using convolutional neural networks, first data and second data corresponding predetermined emotions based on facial expressions and audio data; generating candidate emotion data using the first and second data; determining whether the candidate emotion data predicts a predetermined emotion, and generating a second question to collect additional data for aggregating with the first and second data or determining the authenticity of the user and using the determined authenticity to decide on the user request.

Abstract: There is provided a wireline coring recovery system of a seafloor drilling rig, including: a winch, a rope, a submersible tension sensor, a cover, a main shaft and a catcher. One end of the rope is wound on the winch, and the other end of the rope is connected to an upper end of the catcher after the rope passes over a first pulley provided below the submersible tension sensor and then through a tapered hole on the cover. The catcher is provided in a center hole of the main shaft. The present application further provides a method of using the wireline coring recovery system. By the cooperation of the compression rod skewed teeth, the first rotating core skewed teeth, the second rotating core skewed teeth and the compression spring, the inner core barrel is readily recovered or released.