Abstract: Disclosed herein is a crystalline solvate comprising the compound of formula: methanol, N,N-dimethylformamide, and water, that is useful to prepare a crystalline form of said compound, which is an inhibitor of JAK kinases.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: Methods and systems for arranging hyperlinks on a graphical user-interface (GUI) of a computerized system include receiving, via the GUI, a user selection to display a plurality of hyperlinks, the hyperlinks corresponding to one or more nodes of a first set. The methods and systems further include determining, by a processor, a rank of each hyperlink in the plurality of hyperlinks. Determining a rank includes constructing a first bipartite graph between the one or more nodes of the first set and one or more nodes of a second set, the first set and the second set being mutually exclusive, wherein edges of the first bipartite graph are weighted according to a first criterium and constructing a second bipartite graph between the one or more nodes of the first set and the one or more nodes of the second set, wherein edges of the second bipartite graph are weighted according to a second criterium, different from the first criterium.

Abstract: Systems and methods are provided for calculating authenticity of a human user. One method comprises receiving, via a network, an electronic request from a user device, instantiating a video connection with the user device; generating, using a database of questions, a first question; providing, via the network, the generated question to the user device; analyzing video and audio data received via the connection to extract facial expressions, calculating, using convolutional neural networks, first data and second data corresponding predetermined emotions based on facial expressions and audio data; generating candidate emotion data using the first and second data; determining whether the candidate emotion data predicts a predetermined emotion, and generating a second question to collect additional data for aggregating with the first and second data or determining the authenticity of the user and using the determined authenticity to decide on the user request.

Abstract: A cosmetic compact may comprise a housing including an open top, a front opening, a back side, lateral sides, and a slidable drawer at least partly within the housing having a first position and a second position. The cosmetic compact may include a first actuator positioned above the slidable drawer and accessible from the open top of the housing. The cosmetic compact may include one or more resistive members positioned between the slidable drawer and the first actuator, configured to bias the first actuator upwards, and a second actuator coupled to the back side of the housing and adapted to be compressed when the slidable drawer is closed and in an extended state when the slidable drawer is open. A downward force may be applied to the first actuator to release the slidable drawer from the first position and allow it to assume the second position.

Abstract: Systems and methods are described herein for detecting and measuring inertial parameters, such as acceleration. In particular, the systems and methods relate to vibratory inertial sensors implementing time-domain sensing techniques. Within a composite mass sensor system, a sense mass may oscillate at a frequency different from its actuation frequency, allowing flexibility when integrating the sensor into drive systems without sacrificing sensitivity.

Abstract: The present application provides an integrated card swiping device, which includes: a casing, a circuit board, a magnetic head, a card reader, and a card support for positioning a card. The card support defines therein a card slot for allowing the card to be inserted in, the card support is mounted inside the casing, the magnetic head is electrically connected with the circuit board, the card reader is mounted on the card support, the magnetic head is disposed on the card support, and a side of the casing defines a first opening for allowing the card to be inserted into the card slot.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat inflammatory bowel diseases, and processes and intermediates useful for preparing such compounds.

Abstract: A device for dispensing a cosmetic product may include a container configured to hold a volume of cosmetic product, the container having a closed lower end and an open upper end, a pump assembly disposed at least partially within the open upper end of the container, and a tip connected to the pump assembly, the tip having an outlet for dispensing the cosmetic product. The pump assembly and tip may be configured such that manually tilting the tip actuates the pump assembly to deliver a portion of the volume of cosmetic product to the outlet.

Abstract: A method and system for aggregating user generated content (UGC) are disclosed. The method includes receiving a request for creating UGC, the request including content to be created and identification of a subject event; generating the UGC, the UGC being associated with the subject event; adding data related to the UGC to data describing the subject event; and sending data related to the subject event to users, including the UGC related to the subject event. Embodiments consistent with the present disclosure thus provide various aggregations of UGC associated with a subject event and improve user experience in social networking systems.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: Systems and methods are disclosed herein for multi-axis single-drive inertial devices. A multi-axis single drive inertial device can include a rotational drive configured to oscillate a plurality of accelerometer proof masses and a plurality of gyroscope proof masses about a z axis and signal processing circuitry configured for determining inertial parameters based on motion of the plurality of accelerometer proof masses and the plurality of gyroscope proof masses. The inertial parameters can include acceleration of the inertial device along an x axis perpendicular to the z axis and along a y axis perpendicular to each of the x and z axes, and rotation of the inertial device about each of the x, y, and z axes.

Abstract: The invention provides a crystalline form of the compound of formula: that is an inhibitor of JAK kinases. The invention also provides pharmaceutical compositions comprising such crystalline form and methods of using such crystalline form in mammals suffering from inflammatory bowel diseases.

Abstract: Systems and methods are disclosed herein for extracting system parameters from nonlinear periodic signals from sensors. A sensor such as an inertial device includes a first structure and a second structure that is springedly coupled to the first structure. The sensor is configured to generate an output voltage based on a current between the first and second structures. Monotonic motion of the second structure relative to the first structure causes a reversal in direction of the current.

Abstract: Systems and methods are disclosed herein for extracting system parameters from nonlinear periodic signals from sensors. A sensor such as an inertial device includes a first structure and a second structure that is springedly coupled to the first structure. The sensor is configured to generate an output voltage based on a current between the first and second structures. Monotonic motion of the second structure relative to the first structure causes a reversal in direction of the current.

Abstract: Systems and methods are described herein for determining an inertial parameter. In particular, the systems and methods relate to multiple degrees of freedom inertial sensors implementing time-domain sensing techniques. Within a multiple degrees of freedom inertial sensor system, sense masses may respond to actuation with more than one natural frequency mode, each corresponding to a characteristic motion. Measurement of the inertial parameter can be conducted in the differential natural frequency mode using differential sensing techniques to remove common mode error. The inertial parameter can be acceleration in the vertical dimension. The inertial parameter can be acceleration in the horizontal dimension.

Abstract: Systems and methods are described herein for detecting and measuring inertial parameters, such as acceleration. In particular, the systems and methods relate to vibratory inertial sensors implementing time-domain sensing techniques. Within a composite mass sensor system, a sense mass may oscillate at a frequency different from its actuation frequency, allowing flexibility when integrating the sensor into drive systems without sacrificing sensitivity.

Abstract: System and methods are disclosed herein for converting rotational motion to linear motion. A system comprising a rotational drive can be connected to a proof mass by a first structure comprising a coupling spring. An anchor can be connected to the proof mass by a second structure comprising a drive spring. The coupling spring and the drive spring can be configured to cause the proof mass to move substantially along a first axis when the rotational drive rotates about a second axis.