Patents by Inventor Xiaojun Zhang

Xiaojun Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8420830
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: April 16, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Peter W. Glunz, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata, Luciano Mueller
  • Patent number: 8222453
    Abstract: The present invention provides novel benzamide derivatives of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, W, Y, Z, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: June 7, 2007
    Date of Patent: July 17, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventors: Eldon Scott Priestley, Xiaojun Zhang
  • Patent number: 8200146
    Abstract: A book spread identification arrangement for a board book is provided, the arrangement comprising a plurality of conductive paths, contact means disposed adjacent at least part of at least one of the conductive paths and processing means connected to the conductive paths and configured for processing signals associated with the conductive paths. One selection end of each path is disposed adjacent the spine surface of the book. The contact means comprise one or more conductive surfaces and are arranged, upon opening of the book to a spread, to contact one of a plurality of combinations of one or more of the conductive paths. Each of the plurality of combinations is in a predetermined unique association with a respective single spread of the book. From the processed signals, the processing means are able to determine the particular combination of conductive paths contacted by the contact means and identify to which spread the book is open.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: June 12, 2012
    Assignee: Creata (USA) Inc.
    Inventors: Craig Allen White, Satyajit Deb, Tao Xu, Xiaojun Zhang, Rong Zhang
  • Patent number: 8044242
    Abstract: The present invention relates generally to novel 2-(aryloxy)acetamides of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables W, Y, Z, R7, R8, and R9 are as defined herein. These compounds are selective inhibitors of the serine protease coagulation factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: October 25, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Alexandra A. Nirschl, Xiaojun Zhang
  • Patent number: 8039506
    Abstract: The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, B, C, W, Y, Z1, Z2, Z3, Z4, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: October 18, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata
  • Patent number: 7992850
    Abstract: A method for operating an electromagnetic lift that includes a generator-driven electromagnet comprises adjusting a position of the electromagnet, in response to a first position command. Upon receiving a lift command, an output power level of a generator is established at a predetermined level above a predefined normal power level. In response to an excess release command, the output power level is set to a first predetermined level below the normal power level. In response to a transport command, the output power level is established as approximately the normal power level. Upon receiving a release command, the output power level is established at a second predetermined level below the normal power level.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: August 9, 2011
    Assignee: Caterpillar Inc.
    Inventors: Xiaojun Zhang, Timothy Lynn Cooper, James Ivan Portscheller
  • Patent number: 7794672
    Abstract: A catalytic converter assembly is provided that includes a metallic tubular member having a first end and a second end. The metallic tubular member includes an aperture centrally formed between the first end and the second end. A sensor is received in the aperture and extends into an interior of the metallic tubular member for sensing a content of gas flowing through the metallic tubular member. At least one substrate is disposed within the metallic tubular member. The at least one substrate has a cavity formed in an exterior surface of the at least one substrate and extends radially inward. The cavity is aligned with the aperture of the metallic tubular member and receives a portion of the sensor extending into the interior of the metallic tubular member.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: September 14, 2010
    Assignee: Automotive Components Holdings, LLC
    Inventors: Haimian Cai, Lakshmana Gummadi, Xiaojun Zhang
  • Publication number: 20100227894
    Abstract: The present invention provides novel benzamide derivatives of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, W, Y, Z, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Application
    Filed: June 7, 2007
    Publication date: September 9, 2010
    Inventors: Eldon Scott Priestley, Xiaojun Zhang
  • Publication number: 20100113488
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 6, 2010
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Peter W. Glunz, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata, Luciano Mueller
  • Publication number: 20100041664
    Abstract: The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, B, C, W, Y, Z1, Z2, Z3, Z4, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Application
    Filed: December 17, 2007
    Publication date: February 18, 2010
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata
  • Patent number: 7622585
    Abstract: The present invention relates generally to phenylglycinamide derivatives that inhibit serine proteases. In particular it0 is directed to novel phenylglycinamide derivatives, and analogues thereof, which are useful as selective inhibitors of serine protease enzymes of the coagulation cascade; for example thrombin, factor VIIa, factor Xa, factor XIa, factor IXa, and/or plasma kallikrein. In particular, it relates to compounds that are factor VIIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: November 24, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiaojun Zhang, Eldon Scott Priestley, Alexandra A. Nirschl, Yan Zou
  • Patent number: 7564662
    Abstract: A method for protecting against current overload conditions associated with an electromagnetic lift system comprises receiving current data from a current monitoring device associated with an electromagnetic lift system. The method also includes determining a current level based on the collected current data, and identifying a predetermined overload range corresponding to the current level if the current level exceeds an overload current threshold. The method also includes monitoring a time that the current level is within the predetermined overload range, and providing a command signal to an actuator associated with the electromagnetic lift system if the time that the current level is within the predetermined overload range exceeds a predetermined time limit. The command signal causes the actuator to substantially limit mechanical power provided to a generator associated with the electromagnetic lift system.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: July 21, 2009
    Assignee: Caterpillar Inc.
    Inventors: Xiaojun Zhang, Timothy Lynn Cooper, James Ivan Portscheller, Naga Raja Rao Mosam, Michael Lee Ferguson, Jr.
  • Patent number: 7552698
    Abstract: This invention is about triploid breeding method for different shrimp species especially to the triploid production both in cold-warm water shrimp and tropical species, including the induction of MI triploid shrimp, the triploid induction methods for different shrimp and the development and utilization of revulsants for triploid shrimp. The triploid of cold-water shrimps were obtained by collecting the fertilized eggs and heat shock treatment; while the triploid induction of tropical shrimps were obtained with collection of the fertilized eggs, treatment of the revulsants or cold shock.
    Type: Grant
    Filed: November 29, 2004
    Date of Patent: June 30, 2009
    Assignee: Institute of Oceanology Chinese Academy of Sciences
    Inventors: Jianhai Xiang, Fuhua Li, Linghua Zhou, Xiaojun Zhang
  • Publication number: 20090131473
    Abstract: The present invention relates generally to novel 2-(aryloxy)acetamides of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables W, Y, Z, R7, R8, and R9 are as defined herein. These compounds are selective inhibitors of the serine protease coagulation factor VIIa which can be used as medicaments.
    Type: Application
    Filed: March 8, 2007
    Publication date: May 21, 2009
    Inventors: Alexandra A. Nirschl, Xiaojun Zhang
  • Patent number: 7456195
    Abstract: The present invention provides novel phenylglycinamide derivatives of Formula (I) or (IV): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables W, W1, Y, Z, R7, R8, R9, and R11 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: June 22, 2006
    Date of Patent: November 25, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiaojun Zhang, Alexandra A. Nirschl, Yan Zou, Eldon Scott Priestley
  • Publication number: 20080239612
    Abstract: A method for operating an electromagnetic lift that includes a generator-driven electromagnet comprises adjusting a position of the electromagnet, in response to a first position command. Upon receiving a lift command, an output power level of a generator is established at a predetermined level above a predefined normal power level. In response to an excess release command, the output power level is set to a first predetermined level below the normal power level. In response to a transport command, the output power level is established as approximately the normal power level. Upon receiving a release command, the output power level is established at a second predetermined level below the normal power level.
    Type: Application
    Filed: March 29, 2007
    Publication date: October 2, 2008
    Inventors: Xiaojun Zhang, Timothy Lynn Cooper, James Ivan Portscheller
  • Publication number: 20080204948
    Abstract: A method for protecting against current overload conditions associated with an electromagnetic lift system comprises receiving current data from a current monitoring device associated with an electromagnetic lift system. The method also includes determining a current level based on the collected current data, and identifying a predetermined overload range corresponding to the current level if the current level exceeds an overload current threshold. The method also includes monitoring a time that the current level is within the predetermined overload range, and providing a command signal to an actuator associated with the electromagnetic lift system if the time that the current level is within the predetermined overload range exceeds a predetermined time limit. The command signal causes the actuator to substantially limit mechanical power provided to a generator associated with the electromagnetic lift system.
    Type: Application
    Filed: February 28, 2007
    Publication date: August 28, 2008
    Inventors: Xiaojun Zhang, Timothy Lynn Cooper, James Ivan Portscheller, Naga Raja Rao Mosam, Michael Lee Ferguson
  • Publication number: 20080170972
    Abstract: A catalytic conventer assembly is provided that includes a metallic tubular member having a first end and a second end. The metallic tubular member includes an aperture centrally formed between the first end and the second end. A sensor is received in the aperture and extends into an interior of the metallic tubular member for sensing a content of gas flowing through the metallic tubular member. At least one substrate is disposed within the metallic tubular member. The at least one substrate has a cavity formed in an exterior surface of the at least one substrate and extends radially inward. The cavity is aligned with the aperture of the metallic tubular member and receives a portion of the sensor extending into the interior of the metallic tubular member.
    Type: Application
    Filed: January 11, 2007
    Publication date: July 17, 2008
    Inventors: Haimian Cai, Lakshmana Gummadi, Xiaojun Zhang
  • Publication number: 20080115734
    Abstract: This invention is about triploid breeding method for different shrimp species especially to the triploid production both in cold-warm water shrimp and tropical species, including the induction of MI triploid shrimp, the triploid induction methods for different shrimp and the development and utilization of revulsants for triploid shrimp. The triploid of cold-water shrimps were obtained by collecting the fertilized eggs and heat shock treatment; while the triploid induction of tropical shrimps were obtained with collection of the fertilized eggs, treatment of the revulsants or cold shock.
    Type: Application
    Filed: November 29, 2004
    Publication date: May 22, 2008
    Inventors: Jianhai Xiang, Fuhua Li, Linghua Zhou, Xiaojun Zhang
  • Publication number: 20070294891
    Abstract: A method is provided for manufacturing a catalytic converter. A metallic tubular member is provided. A section of the metallic tubular member is deformed radially inward to form a neck portion. The neck portion has a diameter less than an initial diameter of the metallic tubular member. The tubular member is separated at substantially an axial midpoint of the neck portion for obtaining a first pre-form member having a first conical-shaped end. At least one catalytic element is inserted in the first pre-form member. An outer surface of the first pre-form member is deformed radially inward for securing the catalytic element within the first pre-form member. The first pre-form member is spin-formed for forming a second conical-shaped end opposite the first conical-shaped end.
    Type: Application
    Filed: June 23, 2006
    Publication date: December 27, 2007
    Inventors: Haimian Cai, Xiaojun Zhang, Peng Xiao