Patents by Inventor Xiaolin Liu

Xiaolin Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964677
    Abstract: The present invention relates to a platform door control apparatus based on a double 2-vote-2 architecture, including a security communication and logic processing module, a driver collection module, and a maintenance module, the security communication and logic processing module is separately connected to the driver collection module and the maintenance module, and both the security communication and logic processing module and the driver collection module are devices using the double 2-vote-2 architecture. Compared with the prior art, the present invention has the following advantages of effectively improving linkage efficiency of a signal system and a platform door system, and the like.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: April 23, 2024
    Assignee: CASCO SIGNAL CO., LTD.
    Inventors: Ruiyuan Ye, Xiaolin Tang, Liang Chen, Zhijun Ji, Chang Liu, Chun Yang, Xiaonan Liu, Jing Xu
  • Publication number: 20240086625
    Abstract: An information processing method and apparatus, a terminal, and a storage medium. The information processing method comprises: determining first content in response to a first operation event of a first control in a first document (S11); and adding the first content to the first document on the basis of content information and type information of the first content (S12). The type information comprises first type information and/or second type information, the second type information having an association with the first type information. In the described method, first content can be added to a first document according to content information and type information of the first content, so as to distinguish different ways of adding the first content.
    Type: Application
    Filed: November 16, 2023
    Publication date: March 14, 2024
    Inventors: Lu ZHANG, Wenzong MA, Xinlei GUO, Xiaolin FANG, Hao HUANG, Liang CHEN, Lanjin ZHOU, Linghui ZHOU, Yingtao LIU, Dirun HUANG, Xuebing ZENG, Zejian LIN, Yingjie YOU, Yunzhao TONG, Yuxiang CHEN, Jiawei CHEN
  • Publication number: 20240074990
    Abstract: The present invention relates to application of gossypol and its optical isomers to preparation of an anti-Coronavirus drug. Specifically disclosed is application of pharmaceutically acceptable salts, solvates, isotopes, stereoisomers, stereoisomer mixtures, and tautomers of the gossypol and its optical isomers to preparation of a drug for preventing and/or treating a disease caused by a Coronavirus. The Coronavirus is MERS-CoV, SARS-CoV, or SARS-CoV-2. It is found in the present invention for the first time that the gossypol and its optical isomers can inhibit the activity of Coronavirus 3CL proteases to achieve an anti-Coronavirus effect. The half maximal inhibitory concentrations of gossypol and (?)-gossypol to SARS-CoV proteases and SARS-CoV-2 3CL proteases are all lower than 10 ?M. The anti-Coronavirus 3CL protease effect is good. Therefore, the gossypol and its optical isomers have the potential for use in the preparation of a drug for preventing and/or treating novel Coronavirus infections.
    Type: Application
    Filed: March 18, 2023
    Publication date: March 7, 2024
    Inventors: Xiaolin XIE, Dezhu ZHANG, Zhao MA, Boyang LI, Xuhua ZHOU, Lei TIAN, Chengyuan LIANG, Taotao QIANG, Jingyi LI, Liang XIN, Shaojun ZHANG, Kangxiong WU, Xiuding YANG, Sundian LIU, Yuting LIU
  • Publication number: 20240002553
    Abstract: A process for polymerizing at least one fluoromonomer in an aqueous medium containing initiator and hydrocarbon dispersing agent to form an aqueous dispersion of particles of fluoropolymer. The hydrocarbon dispersing agent comprises a compound of formula I: R—(XZ)n??I wherein R is a hydrophobic hydrocarbon moiety that comprises one or more saturated or unsaturated, non-cyclic or cyclic aliphatic groups, the percentage of total CH3 groups in relation to the total of CH3, CH2 and CH groups in said one or more aliphatic groups being at least about 70%, said hydrophobic moiety being free of siloxane units; wherein each X may be the same or different and represents an ionic hydrophilic moiety; wherein each Z may be a same or different and represents one or more counter ions for said ionic hydrophilic moiety; and wherein n is 1 to 3.
    Type: Application
    Filed: September 30, 2021
    Publication date: January 4, 2024
    Applicant: THE CHEMOURS COMPANY FC, LLC
    Inventors: PHAN LINH TANG, MICHAEL DEEMER, VINCENT FRANCO, STEVEN FURYK, STEPHEN JAMES GETTY, DIPTI DILIP KHASNIS, XIAOLIN LIU, ALEXANDER ANTHONY MARCHIONE, ANDRII MATSNEV, BENJAMIN WEAVER MESSMORE, PETER A. MORKEN, CAMERON PARRISH, ADAM PAUL SMITH, EDWARD PATRICK CAREY
  • Patent number: 11803254
    Abstract: A flexible display apparatus and a control method therefor. The flexible display apparatus comprises: a flexible display panel (10); a bending sensor (11), that is configured to sense bending information of the flexible display panel (10); and a processor, that is coupled to the bending sensor (11), configured to receive the bending information of the bending sensor (11), and determines whether the bending information is valid bending information, and if so, then a currently running application program is controlled according to the valid bending information to perform a corresponding operation. By bending the flexible display panel (10), an application program is controlled to perform a corresponding operation, achieving a convenient, accurate, and effective operation, and improving user experience.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: October 31, 2023
    Assignees: Chengdu BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Hong Zhu, Xiaolin Liu, Chao Sun, Yuanjie Li
  • Patent number: 11761801
    Abstract: The present disclosure provides a multi-layer open channel portable flow measuring device based on a water impulse principle and a flow measuring method; an instantaneous water head height of a water-carrying section, namely, a water level H is measured through a pressure sensor at a bottom of a U-shaped hollow tube; at the same time, layered multi-point velocity measuring components in equidistant layout include a series of position “current meters” composed of tension sensors, hollow punching lightweight steel balls and lightweight elastic steel ropes to measure velocities V1-n of different points, n depends on the layer decided to be arranged according to a channel depth, an instantaneous flow value of the whole water-carrying section is further acquired through multi-layer flow accumulation, and with a simple structure, intelligent control, easy operation and convenient carrying, the present disclosure may further improve the flow measuring precision.
    Type: Grant
    Filed: December 28, 2022
    Date of Patent: September 19, 2023
    Assignee: Soil and Water Conservation Monitoring Center of Pearl River Basin, Pearl River Water Resources Commission of the Ministry of Water Resources
    Inventors: Hao Li, Le Li, Bin Liu, Pingwei Jin, Jun Huang, Xuebing Jiang, Xinyue Kou, Liping Lin, Zhou Xu, Guangyan Wu, Bin Yin, Xiaolin Liu
  • Patent number: 11732044
    Abstract: The invention relates to a novel antibody and an antibody fragment thereof that specifically bind to ALG-3 and a composition comprising the antibody or the antibody fragment. In addition, the invention relates to a nucleic acid encoding the antibody or the antibody fragment thereof, a host cell comprising the nucleic acid, and related use. Furthermore, the invention relates to therapeutic and diagnostic use of the antibody and the antibody fragment. In particular, the invention relates to combination therapy of the antibodies and the antibody fragments described herein with other therapeutic agents, such as anti-PD-1 or anti-PD-L1 antibodies.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: August 22, 2023
    Assignee: INNOVENT BIOLOGICS (SUZHOU) CO., LTD.
    Inventors: Xiaoniu Miao, Huajing Hu, Andy Tsun, Junjian Liu, Xiaolin Liu
  • Publication number: 20230258485
    Abstract: The present disclosure provides a multi-layer open channel portable flow measuring device based on a water impulse principle and a flow measuring method; an instantaneous water head height of a water-carrying section, namely, a water level H is measured through a pressure sensor at a bottom of a U-shaped hollow tube; at the same time, layered multi-point velocity measuring components in equidistant layout include a series of position “current meters” composed of tension sensors, hollow punching lightweight steel balls and lightweight elastic steel ropes to measure velocities V1-n of different points, n depends on the layer decided to be arranged according to a channel depth, an instantaneous flow value of the whole water-carrying section is further acquired through multi-layer flow accumulation, and with a simple structure, intelligent control, easy operation and convenient carrying, the present disclosure may further improve the flow measuring precision.
    Type: Application
    Filed: December 28, 2022
    Publication date: August 17, 2023
    Inventors: Hao Li, Le Li, Bin Liu, Pingwei Jin, Jun Huang, Xuebing Jiang, Xinyue Kou, Liping Lin, Zhou Xu, Guangyan Wu, Bin Yin, Xiaolin Liu
  • Patent number: 11694397
    Abstract: In one aspect of the present application, a computer-implemented method for setting a local coordinate system of a tooth 3D digital model is provided, the method comprises: obtaining a first 3D digital model representing a first tooth, wherein the first 3D digital model is based on a world coordinate system; and setting a local coordinate system for the first 3D digital model using a first artificial neural network based on the first 3D digital model, where the first artificial neural network is a trained deep learning artificial neural network.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: July 4, 2023
    Assignee: WUXI EA MEDICAL INSTRUMENTS TECHNOLOGIES LIMITED
    Inventors: Yang Feng, Xiaolin Liu, Bowen Zhou
  • Publication number: 20230172031
    Abstract: An display panel, including: a flexible display substrate; a circuit board on a back side of the flexible display substrate, wherein the circuit board is bonded and connected to the flexible display substrate, and is provided with a circuit device on a back side of the circuit board far away from the flexible display substrate; an auxiliary bending protection structure on the back side of the flexible display substrate, wherein the auxiliary bending protection structure is fixedly connected to the back side of the flexible display substrate, and the circuit device is in a region where the auxiliary bending protection structure is located.
    Type: Application
    Filed: October 26, 2021
    Publication date: June 1, 2023
    Inventors: Xiaolin LIU, Yue CUI, Hong ZHU, Yuehan WEI
  • Publication number: 20230167200
    Abstract: Provided in the present invention is a method for constructing a multispecific antibody. The method comprises the steps of: (i) constructing a first polynucleotide and a second polynucleotide, respectively, wherein the first polynucleotide and the second polynucleotide respectively encode a first polypeptide containing a CL region and a second polypeptide containing a CH1 region, and a disulfide bond may be formed between the CL region of the first polypeptide and the CH1 region of the second polypeptide, such that the antibody has a heterodimeric form; and (ii) expressing the first polynucleotide and the second polynucleotide to obtain the first polypeptide and the second polypeptide, and dimerize the first polypeptide and the second polypeptide to form a multispecific antibody with a heterodimeric form.
    Type: Application
    Filed: March 30, 2021
    Publication date: June 1, 2023
    Inventors: Xiaolin LIU, Andy TSUN, Tsoyue Joanne SUN, Xiaoniu MIAO, Tao WANG, Shuang DAI
  • Publication number: 20230050236
    Abstract: Disclosed are an anti-icing material with stealth function, a preparation method and use thereof. The anti-icing material with stealth function according to the disclosure includes an electrically insulating and thermally insulating layer, a patterned heating layer, an electrically insulating and thermally conducting layer, and a hydrophobic layer, that are disposed sequentially through stacking, wherein the patterned heating layer has a patterned hollowed-out structure.
    Type: Application
    Filed: March 16, 2022
    Publication date: February 16, 2023
    Inventors: Huawei CHEN, Xiaolin LIU, Jichen CHEN, Yantong ZHU, Zehui ZHAO, Zelinlan WANG, Xiaoyang ZHAN, Zheng MA
  • Publication number: 20230036281
    Abstract: Embodiments of the present disclosure provide a battery, which includes a plurality of energy storage units; and a connecting portion that connects the plurality of energy storage units together in parallel, where the connecting portion is made of a flexible material. The embodiments of the present disclosure further provides a display panel, which includes the above battery and a flexible display module, where the battery is provides on a back side of the flexible display module, the battery is electrically connected with the flexible display module for providing power to the flexible display module.
    Type: Application
    Filed: September 3, 2021
    Publication date: February 2, 2023
    Inventors: Yue CUI, Sitong CHEN, Yuehan WEI, Xiaolin LIU
  • Publication number: 20230002503
    Abstract: Provided are an anti-CAIX single-domain antibody and a VHH chain thereof, as well as related coding sequence, expression vector and host cell; also provided are a production method for said CAIX single-domain antibody and an application thereof.
    Type: Application
    Filed: August 25, 2020
    Publication date: January 5, 2023
    Inventors: Xiaoniu MIAO, Yifeng XU, Gang YI, Zhiyuan LI, Andy TSUN, Xiaolin LIU
  • Patent number: 11538371
    Abstract: A display apparatus and an electronic device relating to the field of display technologies are provided. The display apparatus includes: a first housing, one end of which includes an opening; a second housing slidably connected to the first housing and configured to slide out of a cavity of the first housing via the opening of the first housing; a flexible display screen configured to slide out of the cavity of the first housing along with the second housing when the second housing slides out of the cavity of the first housing; and at least one elastic assembly configured to provide an elastic force to the second housing when the second housing slides out of the cavity of the first housing so that a second lateral outer surface is kept flush with the first lateral outer surface.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: December 27, 2022
    Assignee: BEIJING BOE TECHNOLOGY DEVELOPMENT CO., LTD.
    Inventors: Zongyuan Wang, Lu Liu, Lupeng Bian, Yanyan Yang, Biao Gao, Xiaolin Liu
  • Patent number: 11498972
    Abstract: The present invention relates to an antibody and antibody fragment that specifically binds to OX40 and to a composition comprising said antibody or antibody fragment thereof. In addition, the present invention relates to a nucleic acid encoding the antibody or antibody fragment thereof and a host cell comprising the same, and to a related use thereof. In addition, the present invention relates to the use of the antibody and antibody fragment for treatment and diagnosis.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: November 15, 2022
    Assignee: Innovent Biologics (Suzhou) Co., Ltd.
    Inventors: Andy Tsun, Hemanta Baruah, Xiaolin Liu, Cheng Chen, Junjian Liu, Bingliang Chen, Weifeng Huang
  • Publication number: 20220347289
    Abstract: The present disclosure discloses nucleotide sequences as shown by SEQ ID NO: 1, SEQ ID NO: 2 and the nucleotide sequences having at least 90% homology therewith, which encode peptide antigens of SARS-CoV-2 virus. According to some embodiments of the present disclosure, the nucleotide sequences can be effectively expressed in human cells and produce the corresponding peptides, thereby inducing an immune-protective response accordingly. Thus, the nucleotide sequences of the present disclosure are expected to be developed as a vaccine against SARS-CoV-2 infection.
    Type: Application
    Filed: August 19, 2020
    Publication date: November 3, 2022
    Inventors: Ling Chen, Suhua Guan, Chenchen Yang, Xiaolin Liu
  • Patent number: 11485795
    Abstract: The present invention provides an antibody that specifically binds to proprotein convertase subtilisin/kexin type 9 (PCSK9), an antigen-binding fragment of the antibody, and a composition comprising the antibody or the fragment. Also provided are a nucleic acid that encodes the antibody or the fragment, a host cell containing the nucleic acid, and applications of the antibody and fragment in treatment and diagnosis.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: November 1, 2022
    Assignee: INNOVENT BIOLOGICS (SUZHOU) CO., LTD
    Inventors: Andy Tsun, Eric Krauland, Jonathan P Belk, Xiaoniu Miao, Min Zhang, Nadthakarn Boland, Xiaolin Liu, Dechao Yu
  • Publication number: 20220331416
    Abstract: Provided is a nucleic acid encoding a chimeric CD3 fusion protein and an anti-CD3 based bispecific T cell activator (BiTA) element. Also provided are vectors, engineered immune cells comprising the nucleic acid, the usage thereof and methods for preventing tumor. BiTA secreted by CAB-T cells can simultaneously achieve activation of CAB-T cells and endogenous TCR complexes in non-engineered T cells in tumor, and exert an anti-tumor effect.
    Type: Application
    Filed: September 7, 2020
    Publication date: October 20, 2022
    Inventors: Zhiyuan LI, Gang YI, Andy TSUN, Xiaolin LIU, Weifeng Joanne HUANG, Shaogang PENG
  • Publication number: 20220276724
    Abstract: A flexible display apparatus and a control method therefor. The flexible display apparatus comprises: a flexible display panel (10); a bending sensor (11), that is configured to sense bending information of the flexible display panel (10); and a processor, that is coupled to the bending sensor (11), configured to receive the bending information of the bending sensor (11), and determines whether the bending information is valid bending information, and if so, then a currently running application program is controlled according to the valid bending information to perform a corresponding operation. By bending the flexible display panel (10), an application program is controlled to perform a corresponding operation, achieving a convenient, accurate, and effective operation, and improving user experience.
    Type: Application
    Filed: March 9, 2021
    Publication date: September 1, 2022
    Inventors: Hong ZHU, Xiaolin LIU, Chao SUN, Yuanjie LI