Patents by Inventor Xiaoming Xie

Xiaoming Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7816131
    Abstract: The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-, prostate cancer-, and pancreatic cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of topoisomerase II? and transferrin receptor promoters, particularly in combination with an enhancer. The prostate cancer-specific and pancreatic cancer-specific control sequences utilize composites of tissue-specific control sequences, a two-step transcription amplification sequence, and a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: October 19, 2010
    Assignee: Board of Regents, The University of Texas System
    Inventors: Mien-Chie Hung, Chi-Ping Day, Kun-Ming Rau, Xiaoming Xie, Zheng Li
  • Patent number: 7723104
    Abstract: The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-, prostate cancer-, and pancreatic cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of topoisomerase II? and transferrin receptor promoters, particularly in combination with an enhancer. The prostate cancer-specific and pancreatic cancer-specific control sequences utilize composites of tissue-specific control sequences, a two-step transcription amplification sequence, and a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: May 25, 2010
    Assignee: Board of Regents, The University Of Texas System
    Inventors: Mien-Chie Hung, Chi-Ping Day, Kun-Ming Rau, Xiaoming Xie, Zheng Li
  • Publication number: 20090192101
    Abstract: The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-specific and ovarian cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of fatty acid synthase and claudin 4 promoters, particularly in combination with a two-step transcription amplification sequence and/or a post-transcriptional control sequence. Two ovarian cancer-specific sequences utilize specific regions of hTERT and survivin promoters, particularly in combination with a two-step transcription amplification sequence and/or a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.
    Type: Application
    Filed: November 20, 2007
    Publication date: July 30, 2009
    Inventors: Mien-Chie Hung, Xiaoming Xie, Jing-Yu Lang
  • Publication number: 20080286860
    Abstract: The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-, prostate cancer-, and pancreatic cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of topoisomerase II? and transferrin receptor promoters, particularly in combination with an enhancer. The prostate cancer-specific and pancreatic cancer-specific control sequences utilize composites of tissue-specific control sequences, a two-step transcription amplification sequence, and a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.
    Type: Application
    Filed: January 24, 2007
    Publication date: November 20, 2008
    Inventors: Mien-Chie Hung, Chi-Ping Day, Kun-Ming Rau, Xiaoming Xie, Zheng Li
  • Publication number: 20050260643
    Abstract: The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-, prostate cancer-, and pancreatic cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of topoisomerase II? and transferrin receptor promoters, particularly in combination with an enhancer. The prostate cancer-specific and pancreatic cancer-specific control sequences utilize composites of tissue-specific control sequences, a two-step transcription amplification sequence, and a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.
    Type: Application
    Filed: April 1, 2005
    Publication date: November 24, 2005
    Inventors: Mien-Chie Hung, Chi-Ping Day, Kun-Ming Rau, Xiaoming Xie, Zheng Li
  • Patent number: 6334567
    Abstract: The invention relates to a component and to a method for the production. The component is an electronic component with a micro electronic chip and a carrier which is produced by means of isothermal coagulation.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: January 1, 2002
    Assignees: DaimlerChrysler AG, Shanghai Institue of Metallurgy
    Inventors: Xiaoming Xie, Zhongzhe Shen, Jürgen Freytag, Frank Stubhan