Patents by Inventor Xiaoping Guo

Xiaoping Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11445758
    Abstract: An electronic cigarette includes a housing, wherein the housing is elongate and has a head end disposed toward the user and a tail end extending away from the user. The housing comprises a bottom cover and a shell section. A battery is retained within the housing. An atomizer tank cartridge fits to the housing. An electrical heating apparatus powered by the battery. A groove is formed between the bottom cover and the shell section. A trim piece is mounted between the bottom cover and shell section. The trim piece is a hot-melt material, and connected to the groove via a heating process. The trim piece passes around an external periphery of the housing. The trim piece is an epoxy resin material. The housing further comprises a removable mouthpiece cover attached at a head end.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: September 20, 2022
    Inventors: Xiaoping Guo, Ruyun Guo
  • Publication number: 20220280699
    Abstract: An intracardiac echocardiography catheter includes a shaft and an ultrasound transducer at a distal end of the shaft. The ultrasound transducer includes an outer polymeric encapsulant layer and a nanocoating applied to the outer polymeric encapsulant layer. The nanocoating is configured to provide increased surface lubricity and self-cleaning properties to the ultrasound transducer.
    Type: Application
    Filed: March 2, 2022
    Publication date: September 8, 2022
    Inventor: Xiaoping Guo
  • Patent number: 11413454
    Abstract: A delivery device for delivering a pacing lead to the His bundle of a patient's heart includes an elongated sheath having a distal end, and a plurality of mapping electrodes positioned at the distal end. The distal end of the sheath may have a distal end face, and the mapping electrodes may include two electrodes that diametrically oppose one another at a position exposed on or spaced from the distal end face. The sheath includes a plurality of flexible sections spaced apart from one another, and a pull wire that causes the sheath to deflect from a substantially straight configuration to a dual hinged curved configuration that maneuvers and positions the electrodes in the vicinity of the bundle of His. The sheath may include a PTFE liner having axially oriented, platelet-like fibril features that enable the sheath to be split along its length from a proximal end to the distal end.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: August 16, 2022
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Xiaoping Guo, Erich W. Stoermer
  • Publication number: 20220255409
    Abstract: Provided is a noise reduction method by cutting a corner of a tooth shoulder of a stator of an AC traction motor based on an inscribed arc. Taking a vertex of a corner of the tooth shoulder of the stator as an end point, two points are selected along two sides of the corner of the tooth shoulder of the stator to allow distances from the two points to the end point to be equal. The two points are determined as tangent points D1 and D2 of the inscribed arc. The tangent points D1 and D2 define the inscribed arc along which the corner of the tooth shoulder is cut off.
    Type: Application
    Filed: February 5, 2021
    Publication date: August 11, 2022
    Inventors: Xiaoping ZHANG, Yuxuan GUO, Zhu ZHANG, Guanghui ZHU, Haipeng JIANG, Hongwei CHEN
  • Patent number: 11389571
    Abstract: In various embodiments of the present disclosure, a surgical catheter is provided. The present disclosure provides a catheter shaft that includes a distal portion and a proximal portion. The proximal portion comprises a handle operably connected to the distal portion of the elongated structure. The distal portion three radially positioned polymeric layers. At least two of the layers include chemically dissimilar polymers and at least one of the three layers includes functionalized polyvinylidene fluoride (PVDF).
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: July 19, 2022
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Xiaoping Guo, David P. Johnson
  • Publication number: 20220204630
    Abstract: An antibody or an antigen-binding fragment thereof is capable of specifically recognizing TrkA and uses thereof. The antibody contains a CDR sequence selected from at least one of the following or an amino acid sequence having at least 95% identity with it: heavy chain variable region CDR sequences: SEQ ID NO: 1˜27, light chain variable region CDR sequences: SEQ IN NO: 28˜54. The above antibody can specifically targeted-bind to the TrkA receptor and block the binding of NGF to TrkA.
    Type: Application
    Filed: May 28, 2020
    Publication date: June 30, 2022
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Chao CHEN, Zhiheng REN, Zhuandi HE, Jielian LU, Shushan LIN, Tingting YU, Xiling WEI, Xufang WANG, Le XU, Junji DONG, Xiang LI, Kuo ZHANG, Xueyao YANG, Linfeng GUO, Xiaoping LI, Xiaofeng CHEN, Wenjia LI
  • Patent number: 11331452
    Abstract: Aspects of the present disclosure are directed to intravascular electrophysiology catheters including a catheter handle with a steering-wire locking mechanism.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: May 17, 2022
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Xiaoping Guo, David Hong, John J. Buysman, Steven N. Willard, Ryan K. Buesseler
  • Publication number: 20210386968
    Abstract: Embodiments include a catheter comprising a proximal handle, a distal tip, and a shaft extending between the proximal handle and the distal tip. The shaft comprises an outer polymer layer, and an inner polymer layer disposed adjacent to the outer polymer layer and defining an internal lumen. The inner polymer layer includes a blend of two or more polymers, and the blend of two or more polymers includes PTFE and one or more copolymers.
    Type: Application
    Filed: May 14, 2021
    Publication date: December 16, 2021
    Inventor: Xiaoping Guo
  • Publication number: 20210236766
    Abstract: A method of manufacturing a catheter shaft includes the steps of forming an inner layer of a first polymeric material, forming a plait matrix layer including a second polymeric material about the inner layer, and forming an outer layer of a third polymeric material about the plait matrix layer. The plait matrix layer includes a braided wire mesh partially or fully embedded within the second polymeric material, which is different from at least one of the first polymeric material forming the inner layer and the third polymeric material forming the outer layer. The second polymeric material has a higher yield strain and/or a lower hardness than at least the first polymeric material, and preferably both the first and the third polymeric materials. The first polymeric material and the third polymeric material may be different or the same. The catheter shaft may be formed by stepwise extrusion, co-extrusion, and/or reflow processes.
    Type: Application
    Filed: February 24, 2021
    Publication date: August 5, 2021
    Inventors: Xiaoping Guo, Richard E. Stehr
  • Publication number: 20210162200
    Abstract: The present disclosure relates generally to percutaneous heart pumps including a self-expandable and collapsible impeller housing fabricated from a mesh of a shape memory alloy, such as nitinol, and a base polymer coating and a top polymer coating. Specifically, the present disclosure relates to highly flexible and fluid-impermissible polymer coatings having improved adherence and performance properties on the metallic surfaces of the impeller housing mesh thus improving the overall performance of the percutaneous heart pumps.
    Type: Application
    Filed: March 18, 2019
    Publication date: June 3, 2021
    Applicant: TC1 LLC
    Inventors: Xiaoping GUO, David PANUS
  • Patent number: 10960180
    Abstract: A method of manufacturing a catheter shaft includes the steps of forming an inner layer of a first polymeric material, forming a plait matrix layer including a second polymeric material about the inner layer, and forming an outer layer of a third polymeric material about the plait matrix layer. The plait matrix layer includes a braided wire mesh partially or fully embedded within the second polymeric material, which is different from at least one of the first polymeric material forming the inner layer and the third polymeric material forming the outer layer. The second polymeric material has a higher yield strain and/or a lower hardness than at least the first polymeric material, and preferably both the first and the third polymeric materials. The first polymeric material and the third polymeric material may be different or the same. The catheter shaft may be formed by stepwise extrusion, co-extrusion, and/or reflow processes.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: March 30, 2021
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Xiaoping Guo, Richard E. Stehr
  • Publication number: 20210046233
    Abstract: An expandable cannula for a percutaneous heart pump includes a substantially open proximal end, a substantially open distal end and an elongate central portion disposed between the proximal end and the distal end. The elongate central portion has an inner surface and an opposing outer surface. The expandable cannula is made of a shape memory alloy having an austenite finish temperature Af that is at or below the body temperature of a human patient.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 18, 2021
    Inventors: Xiaoping Guo, David Panus
  • Publication number: 20210046232
    Abstract: An expandable cannula for a percutaneous heart pump includes a substantially open proximal end and a substantially open distal end. The expandable cannula includes an elongate central portion disposed between the proximal end and the distal end, the elongate central portion having an inner surface and an opposing outer surface. A first fluid impermeable film is disposed on at least one of the inner surface and the outer surface. The first fluid impermeable film comprises a polymer and has a thickness within a range of from 10 ?m to 200 ?m.
    Type: Application
    Filed: October 29, 2020
    Publication date: February 18, 2021
    Inventors: Xiaoping Guo, David Panus
  • Patent number: 10918773
    Abstract: Disclosed herein is a collapsible and self-expanding cannula for a percutaneous heart pump. The collapsible and self-expanding cannula comprises an open proximal end, an open distal end, and an elongate fluid-impermissible wall structure that includes a first balloon film, a cannula strut, and a second balloon film. The first balloon film is disposed on an interior surface of the cannula, the second balloon film is disposed on the exterior surface of the cannula, and the cannula strut is between the two balloon films. Together they form an integrated hybrid structure upon thermal fusion bonding. Also disclosed herein is a method of manufacturing the collapsible and self-expanding cannula.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: February 16, 2021
    Assignee: TCI LLC
    Inventors: Xiaoping Guo, David Panus
  • Publication number: 20200406025
    Abstract: A delivery device for delivering a pacing lead to the His bundle of a patient's heart includes an elongated sheath having a distal end, and a plurality of mapping electrodes positioned at the distal end. The distal end of the sheath may have a distal end face, and the mapping electrodes may include two electrodes that diametrically oppose one another at a position exposed on or spaced from the distal end face. The sheath includes a plurality of flexible sections spaced apart from one another, and a pull wire that causes the sheath to deflect from a substantially straight configuration to a dual hinged curved configuration that maneuvers and positions the electrodes in the vicinity of the bundle of His. The sheath may include a PTFE liner having axially oriented, platelet-like fibril features that enable the sheath to be split along its length from a proximal end to the distal end.
    Type: Application
    Filed: June 25, 2019
    Publication date: December 31, 2020
    Inventors: Xiaoping Guo, Erich W. Stoermer
  • Publication number: 20200337375
    Abstract: An electronic cigarette includes a housing, wherein the housing is elongate and has a head end disposed toward the user and a tail end extending away from the user. The housing comprises a bottom cover and a shell section. A battery is retained within the housing. An atomizer tank cartridge fits to the housing. An electrical heating apparatus powered by the battery. A groove is formed between the bottom cover and the shell section. A trim piece is mounted between the bottom cover and shell section. The trim piece is a hot-melt material, and connected to the groove via a heating process. The trim piece passes around an external periphery of the housing. The trim piece is an epoxy resin material. The housing further comprises a removable mouthpiece cover attached at a head end.
    Type: Application
    Filed: April 6, 2020
    Publication date: October 29, 2020
    Inventors: Xiaoping GUO, Ruyun Guo
  • Patent number: 10610293
    Abstract: A guidable, or steerable, or deflectable catheter is provided that includes a proximal portion and a distal portion for insertion into a body cavity. A selectively deflectable segment having an anisotropic bending stiffness for deflection in individual planes is incorporated into the distal portion of the catheter shaft. The deflectable segment comprises a corrugate structure that provides smooth curvatures of desirable configurations, deflection planarity, and easiness.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: April 7, 2020
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Xiaoping Guo
  • Publication number: 20200078559
    Abstract: Aspects of the present disclosure are directed to intravascular electrophysiology catheters including a catheter handle with a steering-wire locking mechanism.
    Type: Application
    Filed: September 5, 2019
    Publication date: March 12, 2020
    Inventors: Xiaoping Guo, David Hong, John J. Buysman, Steven N. Willard, Ryan K. Buesseler
  • Patent number: 10576249
    Abstract: The present disclosure provides a medical device comprising a restraining assembly configured to assist in restraining a catheter shaft in a deflected configuration. The resistance assembly may include an inner restraining assembly and an outer restraining assembly configured to engage one another and create normal and frictional resistances therebetween sufficient to prevent unintentional and/or undesired proximal, retracting movement of an actuator, and thus, to prevent changes in a desired deflected configuration of the catheter shaft. In one embodiment, the restraining assembly is configured to allow for temporary, i.e., reversible, restraining of the catheter shaft in the deflected configuration.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: March 3, 2020
    Assignee: St. Jude Medical Cardiology Division, Inc.
    Inventor: Xiaoping Guo
  • Patent number: 10493708
    Abstract: A method of manufacturing a flexible tubular body for a medical device includes extruding an inner layer from a thermoplastic polymer, pulling it over a mandrel, and tightening it down. If wire lumens were not formed in the inner layer when extruded, polymer spaghetti tubes with wire lumens are laid along the outer surface of the inner layer. Deflection wires are fed into the wire lumens. A wire braid is placed over the inner layer (and spaghetti tubes, if present) and tightened down. The components are encased in an outer polymer layer and a heat shrinkable tube. Pressurized fluid is injected into each wire lumen to maintain the internal diameter thereof greater than the diameter of the deflection wire received therein. Heat is applied to the assembled components, causing the layers to laminate. Once the laminated body has cooled, the heat-shrinkable tube is removed.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: December 3, 2019
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Eric John Wilkowske, Allan Manuel Fuentes, Xiaoping Guo, Xuan Yen Khieu, Linda Kay Nemec, Richard E. Stehr