Patents by Inventor Xiaoping Guo

Xiaoping Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140276643
    Abstract: In various embodiments of the present disclosure, a surgical catheter is provided. The present disclosure provides a catheter shaft that includes a distal portion and a proximal portion. The proximal portion comprises a handle operably connected to the distal portion of the elongated structure. The distal portion three radially positioned polymeric layers. At least two of the layers include chemically dissimilar polymers and at least one of the three layers includes functionalized polyvinylidene fluoride (PVDF).
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Xiaoping Guo, David P. Johnson
  • Publication number: 20140157573
    Abstract: A method of manufacturing a splittable/peelable tubular body of a catheter or sheath wherein the tubular body has a splittable/peelable atraumatic tip is disclosed. The atraumatic tip is generally softer than the tubular body. The tubular body and atraumatic tip each comprise a peel mechanism longitudinally extending along their respective lengths. The peel mechanisms are formed by longitudinally extending regions of interfacial bonding between first and second longitudinally extending strips of polymer material. Each strip forms at least a portion of an outer circumferential surface of the tubular body and atraumatic tip. A region of stress concentration extends along the region of interfacial bonding. The stress concentration facilitates the splitting of the tubular body and atraumatic tip along their respective peel mechanisms.
    Type: Application
    Filed: February 12, 2014
    Publication date: June 12, 2014
    Inventors: Xiaoping Guo, Richard E. Stehr, Vitaliy G. Epshteyn, Bruce P. Holman, Donald A. Sauter, Chad A. Thorstenson, Daniel J. Potter, Nalin S. Perera
  • Patent number: 8734442
    Abstract: An ablation catheter is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode is connected relative to the distal end of the catheter for providing ablation energy to patient tissue. A heat sink is provided that is in thermal contact with the ablation electrode. The heat sink, in addition to being in thermal contact with the ablation electrode, is electrically isolated from the ablation electrode. This allows the heat sink to conduct heat away from the ablation electrode without dissipating electrical energy from the electrode. In this regard, the heat sink may prevent build-up of excess heat within the electrode that may result in blood coagulation and/or tissue charring.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: May 27, 2014
    Inventors: Hong Cao, Xiaoping Guo, Yitzhak I. Shai, Michael Yang, Kedar R. Belhe, Saurav Paul, Riki C. Thao
  • Patent number: 8728055
    Abstract: The present invention is a splitable/peelable reinforced flexible tubular body (10) for a catheter or sheath (12). The body (10) comprises a proximal end (14), a distal end (16), a wall structure (18), and a lumen (20) defined by the wall structure (18). The wall structure (18) extends between the ends and includes a reinforcement layer (22) within the wall structure (18) and a separation line (26) extending longitudinally along the wall structure (18). The separation line (26) is adapted to facilitate the splitting/peeling of the wall structure (18) to allow a medical device such as a pacemaker lead to be removed from within the tubular body (10).
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: May 20, 2014
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Richard E. Stehr, Xiaoping Guo
  • Patent number: 8657789
    Abstract: A splittable/peelable tubular body (2) of a catheter or sheath wherein the tubular body (2) has a splittable/peelable atraumatic tip (14) is disclosed. The atraumatic tip (4) is generally softer than the tubular body (2). The tubular body (2) and atraumatic tip (4) each comprise a peel mechanism longitudinally extending along their respective lengths. The peel mechanisms are formed by longitudinally extending regions of interfacial bonding (11) between first and second longitudinally extending strips (8, 10) of polymer material. Each strip (8, 10) forms at least a portion of an outer circumferential surface of the tubular body (2) and atraumatic tip (4). A region of stress concentration extends along the region of interfacial bonding. The stress concentration facilitates the splitting of the tubular body (2) and atraumatic tip (4) along their respective peel mechanisms.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: February 25, 2014
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Xiaoping Guo, Richard E. Stehr, Vitaliy G. Epshteyn, Bruce P. Holman, Donald A. Sauter, Chad A. Thorstenson, Daniel J. Potter, Nalin S. Perera
  • Patent number: 8647323
    Abstract: A catheter shaft includes an inner layer of a first polymeric material, an intermediate layer of a second polymeric material, an outer layer of a third polymeric material, a first wire reinforcing layer encapsulated between the inner and intermediate layers, and a second wire reinforcing layer encapsulated between the outer and intermediate layers. Typically, the first wire reinforcing layer includes one or more metallic wires helically wound in one direction and the second wire reinforcing layer includes one or more metallic wires helically wound in the opposite direction. The intermediate layer is bonded to the inner and outer layers, as by extruding layers over one another or by thermal lamination or reflow bonding. Typically, the intermediate layer has a larger yield strain and/or a lower flexural modulus and/or a lower durometer than at least one of the inner layer and the outer layer.
    Type: Grant
    Filed: December 30, 2007
    Date of Patent: February 11, 2014
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Xiaoping Guo, David Johnson, Richard E. Stehr
  • Publication number: 20130338663
    Abstract: An ablation catheter is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode is connected relative to the distal end of the catheter for providing ablation energy to patient tissue. A heat sink is provided that is in thermal contact with the ablation electrode. The heat sink, in addition to being in thermal contact with the ablation electrode, is electrically isolated from the ablation electrode. This allows the heat sink to conduct heat away from the ablation electrode without dissipating electrical energy from the electrode. In this regard, the heat sink may prevent build-up of excess heat within the electrode that may result in blood coagulation and/or tissue charring.
    Type: Application
    Filed: May 24, 2013
    Publication date: December 19, 2013
    Inventors: Hong Cao, Xiaoping Guo, Yitzhak I. Shai, Michael Yang, Kedar Ravindra Belhe, Saurav Paul, Riki Chou Thao
  • Publication number: 20130300036
    Abstract: The present invention is a method of manufacturing a flexible tubular body for catheter, sheath or similar medical device. The method comprises pre-extruding an inner layer of the body from a thermoplastic polymer and then pulling the inner layer over a mandrel and tightening the layer down. If wire lumens were not integrally formed in the inner layer when pre-extruded, then two polymer spaghetti tubes, each with wire lumens, are laid 180 degrees apart axially along the outer surface of the inner layer. Deflection wires are then fed into the wire lumens. A cylindrical wire braid is woven or pulled over the inner layer (and the spaghetti tubes, as the case may be) and tightened down. The aforementioned components are then encased in an outer polymer layer. A heat-shrinkable tube is then placed over the outer layer.
    Type: Application
    Filed: September 24, 2012
    Publication date: November 14, 2013
    Inventors: Eric John Wilkowske, Allan Manuel Fuentes, Xiaoping Guo, Xuan Yen Khieu, Linda Kay Nemec, Richard E. Stehr
  • Publication number: 20130197481
    Abstract: A method of manufacturing a catheter shaft includes the steps of forming an inner layer of a first polymeric material, forming a plait matrix layer including a second polymeric material about the inner layer, and forming an outer layer of a third polymeric material about the plait matrix layer. The plait matrix layer includes a braided wire mesh partially or fully embedded within the second polymeric material, which is different from at least one of the first polymeric material forming the inner layer and the third polymeric material forming the outer layer. The second polymeric material has a higher yield strain and/or a lower hardness than at least the first polymeric material, and preferably both the first and the third polymeric materials. The first polymeric material and the third polymeric material may be different or the same. The catheter shaft may be formed by stepwise extrusion, co-extrusion, and/or reflow processes.
    Type: Application
    Filed: March 12, 2013
    Publication date: August 1, 2013
    Inventors: Xiaoping Guo, Richard E. Stehr
  • Patent number: 8449537
    Abstract: An ablation catheter is provided for ablating internal tissue of a patient. The catheter includes a distal end that is adapted to be inserted into a body cavity relative to a desired location therein (e.g., within the heart). An ablation electrode is connected relative to the distal end of the catheter for providing ablation energy to patient tissue. A heat sink is provided that is in thermal contact with the ablation electrode. The heat sink, in addition to being in thermal contact with the ablation electrode, is electrically isolated from the ablation electrode. This allows the heat sink to conduct heat away from the ablation electrode without dissipating electrical energy from the electrode. In this regard, the heat sink may prevent build-up of excess heat within the electrode that may result in blood coagulation and/or tissue charring.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: May 28, 2013
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Hong Cao, Xiaoping Guo, Isaac Shai, Michael Yang, Kedar Ravindra Belhe, Saurav Paul, Chou Thao
  • Patent number: 8431057
    Abstract: A method of manufacturing a catheter shaft includes the steps of forming an inner layer of a first polymeric material, forming a plait matrix layer including a second polymeric material about the inner layer, and forming an outer layer of a third polymeric material about the plait matrix layer. The plait matrix layer includes a braided wire mesh partially or fully embedded within the second polymeric material, which is different from at least one of the first polymeric material forming the inner layer and the third polymeric material forming the outer layer. The second polymeric material has a higher yield strain and/or a lower hardness than at least the first polymeric material, and preferably both the first and the third polymeric materials. The first polymeric material and the third polymeric material may be different or the same. The catheter shaft may be formed by stepwise extrusion, co-extrusion, and/or reflow processes.
    Type: Grant
    Filed: December 30, 2007
    Date of Patent: April 30, 2013
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Xiaoping Guo, Richard E. Stehr
  • Patent number: 8273285
    Abstract: The present invention is a method of manufacturing a flexible tubular body for catheter, sheath or similar medical device. The method comprises pre-extruding an inner layer of the body from a thermoplastic polymer and then pulling the inner layer over a mandrel and tightening the layer down. If wire lumens were not integrally formed in the inner layer when pre-extruded, then two polymer spaghetti tubes, each with wire lumens, are laid 180 degrees apart axially along the outer surface of the inner layer. Deflection wires are then fed into the wire lumens. A cylindrical wire braid is woven or pulled over the inner layer (and the spaghetti tubes, as the case may be) and tightened down. The aforementioned components are then encased in an outer polymer layer. A heat-shrinkable tube is then placed over the outer layer.
    Type: Grant
    Filed: January 10, 2005
    Date of Patent: September 25, 2012
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Eric John Wilkowske, Allan Manuel Fuentes, Xiaoping Guo, Xuan Yen Khieu, Linda Kay Nemec, Richard E. Stehr
  • Publication number: 20120172840
    Abstract: In various embodiments, a surgical catheter is provided. The catheter may comprise one or more hydrophobic barrier layers made from an ethylene-pertfluoroethylenepropylene (“EFEP”) copolymer. Additionally, the catheter may comprise another polymer layer made from a reactive polar polymer. In at least one embodiment, the reactive polar polymer may be a modified-poly(ether block amide) (“PEBA”) copolymer, such as an amine-terminated PEBA. Moreover, in various embodiments, a composition is provided that may comprise a reactive polar polymer bonded to an EFEP copolymer.
    Type: Application
    Filed: December 29, 2010
    Publication date: July 5, 2012
    Inventors: Xiaoping Guo, James V. Kauphusman, David P. Johnson, Karen L. Armstrong
  • Patent number: 7985215
    Abstract: A guidable, or steerable, or deflectable catheter is provided that includes a proximal portion and a distal portion for insertion into a body cavity. A selectively deflectable segment having an anisotropic bending stiffness for deflection in individual planes is incorporated into the distal portion of the catheter shaft. Upon actuation of pull wires, the distal deflectable segment may be deflected to move/sweep the distal catheter tip through a sweeping plane. The anisotropic bending stiffness of the distal deflectable segment permits in-plane movement of the distal catheter tip in the sweeping plane while resisting any out-of-plane movements. In one arrangement, stiffening elements are selectively disposed within the distal deflectable segment such that the out-of-plane bending stiffness is largely increased and greater than the in-plane bending stiffness for deflection in the sweeping plane.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: July 26, 2011
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Xiaoping Guo, Troy T. Tegg, Richard E. Stehr
  • Publication number: 20100168270
    Abstract: The invention relates to biocompatible polycarbonate/polyamide polymer compositions for use in medical and surgical devices. Additional additives, crosslinking agents, phosphites, and optionally a radiopaque filler or fillers can be used to produce the high performance compositions desired. The polymer compositions have improved melt processability along with balanced or enhanced physical and mechanical properties, especially when combined or over-extruded onto or covering other polymer layers, such as soft and/or flexible layers commonly used in medical device applications and catheter tips, for example.
    Type: Application
    Filed: December 31, 2008
    Publication date: July 1, 2010
    Inventors: Xiaoping Guo, David P. Johnson, Richard E. Stehr
  • Publication number: 20090171348
    Abstract: A guidable, or steerable, or deflectable catheter is provided that includes a proximal portion and a distal portion for insertion into a body cavity. A selectively deflectable segment having an anisotropic bending stiffness for deflection in individual planes is incorporated into the distal portion of the catheter shaft. Upon actuation of pull wires, the distal deflectable segment may be deflected to move/sweep the distal catheter tip through a sweeping plane. The anisotropic bending stiffness of the distal deflectable segment permits in-plane movement of the distal catheter tip in the sweeping plane while resisting any out-of-plane movements. In one arrangement, stiffening elements are selectively disposed within the distal deflectable segment such that the out-of-plane bending stiffness is largely increased and greater than the in-plane bending stiffness for deflection in the sweeping plane.
    Type: Application
    Filed: December 28, 2007
    Publication date: July 2, 2009
    Inventors: Xiaoping Guo, Troy T. Tegg, Richard E. Stehr
  • Publication number: 20090166913
    Abstract: A method of manufacturing a catheter shaft includes the steps of forming an inner layer of a first polymeric material, forming a plait matrix layer including a second polymeric material about the inner layer, and forming an outer layer of a third polymeric material about the plait matrix layer. The plait matrix layer includes a braided wire mesh partially or fully embedded within the second polymeric material, which is different from at least one of the first polymeric material forming the inner layer and the third polymeric material forming the outer layer. The second polymeric material has a higher yield strain and/or a lower hardness than at least the first polymeric material, and preferably both the first and the third polymeric materials. The first polymeric material and the third polymeric material may be different or the same. The catheter shaft may be formed by stepwise extrusion, co-extrusion, and/or reflow processes.
    Type: Application
    Filed: December 30, 2007
    Publication date: July 2, 2009
    Inventors: Xiaoping Guo, Richard E. Stehr
  • Publication number: 20090171319
    Abstract: A catheter shaft includes an inner layer of a first polymeric material, an intermediate layer of a second polymeric material, an outer layer of a third polymeric material, a first wire reinforcing layer encapsulated between the inner and intermediate layers, and a second wire reinforcing layer encapsulated between the outer and intermediate layers. Typically, the first wire reinforcing layer includes one or more metallic wires helically wound in one direction and the second wire reinforcing layer includes one or more metallic wires helically wound in the opposite direction. The intermediate layer is bonded to the inner and outer layers, as by extruding layers over one another or by thermal lamination or reflow bonding. Typically, the intermediate layer has a larger yield strain and/or a lower flexural modulus and/or a lower durometer than at least one of the inner layer and the outer layer.
    Type: Application
    Filed: December 30, 2007
    Publication date: July 2, 2009
    Inventors: Xiaoping Guo, David P. Johnson, Richard E. Stehr
  • Publication number: 20090043285
    Abstract: The present invention is a splitable/peelable reinforced flexible tubular body (10) for a catheter or sheath (12). The body (10) comprises a proximal end (14), a distal end (16), a wall structure (18), and a lumen (20) defined by the wall structure (18). The wall structure (18) extends between the ends and includes a reinforcement layer (22) within the wall structure (18) and a separation line (26) extending longitudinally along the wall structure (18). The separation line (26) is adapted to facilitate the splitting/peeling of the wall structure (18) to allow a medical device such as a pacemaker lead to be removed from within the tubular body (10).
    Type: Application
    Filed: June 14, 2005
    Publication date: February 12, 2009
    Inventors: Richard E. Stehr, Xiaoping Guo
  • Publication number: 20080208128
    Abstract: A splittable/peelable tubular body (2) of a catheter or sheath wherein the tubular body (2) has a splittable/peelable atraumatic tip (14) is disclosed. The atraumatic tip (4) is generally softer than the tubular body (2). The tubular body (2) and atraumatic tip (4) each comprise a peel mechanism longitudinally extending along their respective lengths. The peel mechanisms are formed by longitudinally extending regions of interfacial bonding (11) between first and second longitudinally extending strips (8, 10) of polymer material. Each strip (8, 10) forms at least a portion of an outer circumferential surface of the tubular body (2) and atraumatic tip (4). A region of stress concentration extends along the region of interfacial bonding. The stress concentration facilitates the splitting of the tubular body (2) and atraumatic tip (4) along their respective peel mechanisms.
    Type: Application
    Filed: April 28, 2006
    Publication date: August 28, 2008
    Inventors: Xiaoping Guo, Richard E. Stehr, Vitaliy G. Epshteyn, Bruce P. Holman, Donald A. Sauter, Chad A. Thorstenson, Daniel J. Potter, Nalin S. Perera