Patents by Inventor Xiaowu Chen

Xiaowu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9036860
    Abstract: The invention discloses a method for editing propagation of video and image content based on local feature structure preservation, comprising: mapping all pixels in the input original image and/or video key frames to a selected feature space; finding K nearest neighbor pixels for each pixel according to feature vectors' Euclidean distance in the selected feature space; using Locally Linear Embedding (LLE) dimension reduction to construct the locally linear relationship between each pixel and its K nearest neighbor pixels in the selected feature space; According to the present invention, it is possible to accurately perform such image or video processing as automatic color transformation, interactive color editing, gray image colorization, video cloning and image matting.
    Type: Grant
    Filed: December 4, 2012
    Date of Patent: May 19, 2015
    Assignee: Beihang University
    Inventors: Xiaowu Chen, Dongqing Zou, Qinping Zhao, Jianwei Li, Feng Ding
  • Publication number: 20150084955
    Abstract: A method of constructing 3D clothing model based on single image, estimating a 3D model of human body of an inputted image and constructing 3D clothing plane according to the clothing silhouette of the inputted image. The method includes utilizing the 3D clothing plane and the 3D model of human body to generate a smooth 3D clothing model through a deformation algorithm. A decomposition algorithm of intrinsic image is utilized along with a shape-from-shading algorithm to acquire a set of detail information of clothing from the inputted image. A weighted Laplace editing algorithm is utilized to shift the acquired detail information of clothing to the smooth 3D clothing model to yield a final 3D clothing model. A 3D clothing model is used to generate the surface geometry details including folds, wrinkles.
    Type: Application
    Filed: July 28, 2014
    Publication date: March 26, 2015
    Inventors: Xiaowu CHEN, Qiang FU, Qinping ZHAO, Bin ZOU, Kan GUO
  • Patent number: 8987250
    Abstract: Compounds disclosed herein including compounds of formula I?: and salts thereof are provided. Pharmaceutical compositions comprising compounds disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection using compounds disclosed herein are also provided.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: March 24, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Kerim Babaoglu, Gediminas Brizgys, Jake Cha, Xiaowu Chen, Hongyan Guo, Randall L. Halcomb, Xiaochun Han, Richard Huang, Hongtao Liu, Ryan McFadden, Michael L. Mitchell, Yingmei Qi, Paul A. Roethle, Lianhong Xu, Hong Yang
  • Publication number: 20150030312
    Abstract: This invention provides a method of sparse representation of contents of high-resolution video images which supports content editing and propagation. It mainly comprises five steps which are: (1) to input the original images or videos of high resolution to summarize the characteristic information of their pixels; (2) to acquire the highly sparse samples of the original images or videos through the sparse representation technique; (3) to reconstruct each pixel of the input images or videos with a small number of the original sparse samples to calculate a coefficient of reconstruction; (4) to edit and propagate the original sparse samples to yield a result of new sparse samples; (5) to generate a result of final images or videos of high resolution according to the result of sparse samples and the coefficient of reconstruction. This invention only edits and propagates the highly sparse samples rather than all the information of pixels.
    Type: Application
    Filed: July 16, 2014
    Publication date: January 29, 2015
    Inventors: Xiaowu CHEN, Dongqing ZHOU, Qinping ZHAO, Jianwei LI
  • Publication number: 20150025039
    Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: June 19, 2014
    Publication date: January 22, 2015
    Inventors: Constantine G. BOOJAMRA, Carina E. CANNIZZARO, James M. CHEN, Xiaowu CHEN, Aesop CHO, Lee S. CHONG, Maria FARDIS, Haolun JIN, Ralph HIRSCHMANN, Alan X. HUANG, Choung U. KIM, Thorsten A. KIRSCHBERG, Christopher P. LEE, William A. LEE, Richard L. MACKMAN, David Y. MARKEVITCH, David A. OARE, Vidya K. PRASAD, Hyung-Jung PYUN, Adrian S. RAY, Rosemarie O'SHEA, Sundaramoorthi SWAMINATHAN, William J. WATKINS, Jennifer R. ZHANG
  • Patent number: 8871785
    Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: October 28, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Carina E. Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Haolun Jin, Ralph Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten A. Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie O'Shea, Sundaramoorthi Swaninathan, William J. Watkins, Jennifer R. Zhang
  • Publication number: 20140221356
    Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: December 19, 2013
    Publication date: August 7, 2014
    Inventors: Haolun JIN, Scott E. LAZERWITH, Teresa Alejandra TREJO MARTIN, Elizabeth M. BACON, Jeromy J. COTTELL, Zhenhong R. CAI, Hyung-Jung PYUN, Philip Anthony MORGANELLI, Mingzhe JI, James G. TAYLOR, Xiaowu CHEN, Michael R. MISH, Manoj C. DESAI
  • Publication number: 20140071347
    Abstract: The invention discloses a method for editing propagation of video and image content based on local feature structure preservation, comprising: mapping all pixels in the input original image and/or video key frames to a selected feature space; finding K nearest neighbor pixels for each pixel according to feature vectors' Euclidean distance in the selected feature space; using Locally Linear Embedding (LLE) dimension reduction to construct the locally linear relationship between each pixel and its K nearest neighbor pixels in the selected feature space; According to the present invention, it is possible to accurately perform such image or video processing as automatic color transformation, interactive color editing, gray image colorization, video cloning and image matting.
    Type: Application
    Filed: December 4, 2012
    Publication date: March 13, 2014
    Applicant: BEIHANG UNIVERSITY
    Inventors: Xiaowu Chen, Dongqing Zou, Qinping Zhao, Jianwei Li, Feng Ding
  • Publication number: 20130281433
    Abstract: Compounds disclosed herein including compounds of formula I?: and salts thereof are provided. Pharmaceutical compositions comprising compounds disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection using compounds disclosed herein are also provided.
    Type: Application
    Filed: April 19, 2013
    Publication date: October 24, 2013
    Inventors: Kerim Babaoglu, Gediminas Brizgys, Jake Cha, Xiaowu Chen, Hongyan Guo, Randall L. Halcomb, Xiaochun Han, Richard Huang, Hongtao Liu, Ryan McFadden, Michael L. Mitchell, Yingmei Qi, Paul A. Roethle, Lianhong Xu, Hong Yang
  • Publication number: 20110288053
    Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 20, 2011
    Publication date: November 24, 2011
    Applicant: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Heolun Jin, Ralph F. Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoothi Swaninathan, William J. Watkins, Jenneifer Zhang
  • Patent number: 8022083
    Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: September 20, 2011
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Haolun Jin, Ralph F. Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang
  • Publication number: 20110071101
    Abstract: The invention is related to phosphorus substituted nucleoside compounds and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: April 9, 2008
    Publication date: March 24, 2011
    Inventors: Constantine G. Boojamra, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Christopher P. Lee, David A. Oare, Vidya K. Prasad, Adrian S. Ray, Sundaramoorthi Swaminathan, William J. Watkins
  • Publication number: 20100022467
    Abstract: The invention is related to phosphorus substituted anti-cancer compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: September 2, 2008
    Publication date: January 28, 2010
    Inventors: Constantine G. Boojamra, Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Steven Krawczyk, Christopher P. Lee, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Peter H. Nelson, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang, Lijun Zhang
  • Patent number: 7649015
    Abstract: Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: January 19, 2010
    Assignee: Gilead Sciences, Inc.
    Inventors: Murty N. Arimili, Xiaowu Chen, Maria Fardis, Gong-Xin He, Haolun Jin, Choung U. Kim, William A. Lee, Kuei-Ying Lin, Hongtao Liu, Richard L. Mackman, Michael L. Mitchell, Hyung-Jung Pyun, Mark Sparacino, Sundaramoorthi Swaminathan, Jianying Wang, Matthew A. Williams, Lianhong Xu, Zheng-Yu Yang, Richard H. Yu, Jiancun Zhang, Lijun Zhang
  • Patent number: 7645747
    Abstract: The invention is related to phosphorus substituted therapeutic agents, compositions containing such phosphorus substituted agents, and therapeutic methods that include the administration of such phosphorus substituted agents, as well as to processes and intermediates useful for preparing such agents.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: January 12, 2010
    Assignee: Gilead Sciences, Inc.
    Inventors: Constantine G. Boojamra, Carina E. Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Manoj Desai, Maria Fardis, Craig S. Gibbs, Ralph F. Hirschmann, Alan X. Huang, Haolun Jin, Choung U. Kim, Thorsten A. Kirschberg, Steven Krawczyk, Christopher P. Lee, William A. Lee, Kuei-Ying Lin, Richard L. Mackman, David Y. Markevitch, Peter H. Nelson, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang, Lijun Zhang
  • Publication number: 20090275535
    Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 1, 2008
    Publication date: November 5, 2009
    Inventors: Constantine G. Boojamra, Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Haolun Jin, Ralph F. Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang
  • Publication number: 20090247488
    Abstract: The invention is related to phosphorus substituted anti-inflammatory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: June 25, 2008
    Publication date: October 1, 2009
    Inventors: Carina Cannizzaro, James Chen, Xiaowu Chen, Aesop Cho, Lee Chong, Maria Fardis, Craig Gibbs, Ralp F. Hirschmann, Thorsten Kirschberg, Christopher P. Lee, Kuei-Ying Lin, Richard L. Mackman, Peter H. Nelson, David A. Oare, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang
  • Publication number: 20090227543
    Abstract: The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 1, 2008
    Publication date: September 10, 2009
    Inventors: Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Manoj Desai, Maria Fardis, Alan X. Huang, Thorsten Kirschberg, Christopher P. Lee, Richard L. Mackman, Peter H. Nelson, Hyung-Jung Pyun, Adrian S. Ray, William J. Watkins, Jennifer R. Zhang, Sundaramoorthi Swaminathan
  • Publication number: 20090181930
    Abstract: The invention is related to phosphorus substituted kinase inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 2, 2008
    Publication date: July 16, 2009
    Inventors: Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Manoj Desai, Maria Fardis, Thorsten Kirschberg, Richard L. Mackman, Sundaramoorthi Swaminathan, William J. Watkins
  • Publication number: 20090131372
    Abstract: The invention is related to phosphorus substituted compounds with activity for treating metabolic diseases and/or disorders, e.g., diabetes and hypercholesterolemia, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: June 24, 2008
    Publication date: May 21, 2009
    Inventors: James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Thorsten Kirschberg, Steven Krawczyk, Hyung-Jung Pyun, William J. Watkins