Abstract: A method utilizing optical path difference in two-phase flow for analytical calculation of particle size gradation and solid content comprises: changing a width of measurement area of a laser particle size analyzer, and collecting extinction values at two different optical path lengths and a scattered light intensity signal on each detector during monitoring; utilizing the scattered light intensity signal with a long optical path to subtract the scattered light intensity signal with a short optical path on each detector to obtain a set of new scattered light intensity signals with background subtracted; processing particle size distribution inversion calculations for the set of scattered light intensity signals with background subtracted to obtain gradation data of solid particles; processing subtraction of the logarithm of the extinction value of the short optical path from the logarithm of the extinction value of the long optical path to obtain new extinction value; calculating the solid content based on th

Abstract: A method and system for correcting misalignment of, or of aligning, images of one or more portions of a subject, the images obtained by a two- or three-dimensional medical imaging modality. The method comprises: in consecutive first and second two- or three-dimensional sub-volume scans, (a) identifying at least one first portion and at least one second portion respectively of a common anatomical feature or structure, and/or (b) determining first and second axes of objects (such as anatomical features or structures, or portions thereof) in the first and second sub-volume scans, respectively; determining, based on those portions, or based on the axes, a transformation that aligns or brings into registration the portions; aligning the first and second sub-volume scans by applying the transformation and forming aligned first and second sub-volume scans; generating an aligned image from the aligned first and second sub-volume scans; and outputting the aligned image.

Abstract: The present application discloses novel and inventive methods, apparatuses, and the required molecules to detect compounds (analytes) utilizing antibodies or other protein-binding molecules and nanopore-detectable tags using specially designed nanopores, coupled with ionic current readout, to provide a single molecule electronic detection solution, offering unique opportunities for multiplexing and quantitation.

Abstract: Examples herein describe integrated circuit (IC) devices with cooling plates. An IC device includes a circuit board and an IC die mounted on a first side of the circuit board. A thermally conductive plate is disposed over the first side of the circuit board. Thermal interface material is disposed between the IC die and the thermally conductive plate. The IC device includes fins having a first end in contact with a side of the thermally conductive plate that contacts the thermal interface material and a second end that extends beyond a second side of the circuit board.

Abstract: This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides.

Abstract: This invention provides nucleotide analogues each of which comprises a tag comprising one or more Forster resonance energy transfer (FRET) acceptor fluorophores, a nucleotide polymerase having one or more FRET donor fluorophores, and methods for sequencing single-stranded DNA.

Abstract: A fiber-metal laminate having a honeycomb sandwich structure and a preparation method thereof are provided. Firstly, based on material reduction processing technology, a recessed polygonal structure is obtained according to a design trajectory, and an upper layer and a lower layer are closed to form a recessed honeycomb sandwich structure. Then, processed surfaces of the upper layer and the lower layer are chemically treated to passivate the processed surfaces, with the aim of increasing the adhesion between a fiber layer and the metal layers. Then, a viscous mixture is filled into the recessed structures of the metal layers to ensure the multifunctional characteristics and impact resistance of the fiber-metal laminate. Then, a fiber prepreg is laid between the upper layer and the lower layer to obtain a prefabricated fiber-metal laminate. Finally, the prefabricated fiber-metal laminate undergoes thermal curing treatment under pressure in a hot-pressing tank, thereby obtaining the fiber-metal laminate.

Abstract: A method and system for correcting misalignment of, or of aligning, images of one or more portions of a subject, the images obtained by a two- or three-dimensional medical imaging modality. The method comprises: in consecutive first and second two- or three-dimensional sub-volume scans, (a) identifying at least one first portion and at least one second portion respectively of a common anatomical feature or structure, and/or (b) determining first and second axes of objects (such as anatomical features or structures, or portions thereof) in the first and second sub-volume scans, respectively; determining, based on those portions, or based on the axes, a transformation that aligns or brings into registration the portions; aligning the first and second sub-volume scans by applying the transformation and forming aligned first and second sub-volume scans; generating an aligned image from the aligned first and second sub-volume scans; and outputting the aligned image.

Abstract: The present application discloses novel and inventive methods, apparatuses, and the required molecules to detect compounds (analytes) utilizing antibodies or other protein-binding molecules and nanopore-detectable tags using specially designed nanopores, coupled with ionic current readout, to provide a single molecule electronic detection solution, offering unique opportunities for multiplexing and quantitation.

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.

Abstract: Disclosed herein are a backplate for a PCB and a method for protecting and cooling a PCB and its backside components. The backplate, which can be attached to a backside of a PCB, includes a second sheet sandwiched between a first sheet and a third sheet. The backplate may include a thermal pad penetrating the first sheet and contacting the second sheet. The second sheet has a higher thermal conductivity than the conductivities of the first and third sheets.

Abstract: Disclosed herein are highly accurate approaches for single molecule electronic nanopore-based SBS.

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.

Abstract: The present disclosure provides a display apparatus, a timing controller and a control method thereof. The control method of the timing controller includes: receiving and storing a video stream, where the video stream includes n initial display frames arranged in sequence, n is greater than or equal to 2, and a frame frequency of each initial display frame sequentially increases or decreases from a first initial display frame to an n-th initial display frame; generating a luminance control signal and n modified display frames according to the n initial display frames, where the n modified display frames respectively correspond to the n initial display frames; the luminance control signal is a pulse signal and includes n control segments, and the n control segments respectively correspond to the n modified display frames; and sending the luminance control signal and the n modified display frames to a display panel, so that the display panel displays according to the modified display frames.

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.

Abstract: A method and system for correcting misalignment of, or of aligning, images of one or more portions of a subject, the images obtained by a two- or three-dimensional medical imaging modality. The method comprises: in consecutive first and second two- or three-dimensional sub-volume scans, (a) identifying at least one first portion and at least one second portion respectively of a common anatomical feature or structure, and/or (b) determining first and second axes of objects (such as anatomical features or structures, or portions thereof) in the first and second sub-volume scans, respectively; determining, based on those portions, or based on the axes, a transformation that aligns or brings into registration the portions; aligning the first and second sub-volume scans by applying the transformation and forming aligned first and second sub-volume scans; generating an aligned image from the aligned first and second sub-volume scans; and outputting the aligned image.

Abstract: A method utilizing optical path difference in two-phase flow for analytical calculation of particle size gradation and solid content comprises: changing a width of measurement area of a laser particle size analyzer, and collecting extinction values at two different optical path lengths and a scattered light intensity signal on each detector during monitoring; utilizing the scattered light intensity signal with a long optical path to subtract the scattered light intensity signal with a short optical path on each detector to obtain a set of new scattered light intensity signals with background subtracted; processing particle size distribution inversion calculations for the set of scattered light intensity signals with background subtracted to obtain gradation data of solid particles; processing subtraction of the logarithm of the extinction value of the short optical path from the logarithm of the extinction value of the long optical path to obtain new extinction value; calculating the solid content based on th

Abstract: The invention provides various orthogonal nucleotide analogues and methods for using combinations of said various orthogonal nucleotide analogues for sequencing by synthesis.

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.

Abstract: A fiber-metal laminate having a honeycomb sandwich structure and a preparation method thereof are provided. Firstly, based on material reduction processing technology, a recessed polygonal structure is obtained according to a design trajectory, and an upper layer and a lower layer are closed to form a recessed honeycomb sandwich structure. Then, processed surfaces of the upper layer and the lower layer are chemically treated to passivate the processed surfaces, with the aim of increasing the adhesion between a fiber layer and the metal layers. Then, a viscous mixture is filled into the recessed structures of the metal layers to ensure the multifunctional characteristics and impact resistance of the fiber-metal laminate. Then, a fiber prepreg is laid between the upper layer and the lower layer to obtain a prefabricated fiber-metal laminate. Finally, the prefabricated fiber-metal laminate undergoes thermal curing treatment under pressure in a hot-pressing tank, thereby obtaining the fiber-metal laminate.