Abstract: Inhibitors of ALCAT1 are described having the general formula: (I). These compounds offer a treatment for aging and age-related diseases.

Abstract: Language interoperability between source code programs not compatible with an interprocedural static code analyzer is achieved through language-independent representations of the programs. The source code programs are transformed into respective intermediate language instructions from which a language-independent control flow graph and a language-independent type environment is created. A program compatible with the interprocedural static code analyzer is generated from the language-independent control flow graph and the language-independent type environment in order to utilize the interprocedural static code analyzer to detect memory safety faults.

Abstract: A code completion tool uses machine learning models to more precisely predict the likelihood of a method invocation completing a code fragment that follows one or more method invocations of different classes in a same document during program development. In one aspect, the machine learning model is a n-order Markov chain model that is trained on features that represent characteristics of the context of method invocations found in commonly-used programs from a sampled population. The machine learning model is implemented as a hash table contained a ranked order of hash values in descending order of probability of completing a partially-formed method invocation.

Abstract: Language interoperability between source code programs not compatible with an interprocedural static code analyzer is achieved through language-independent representations of the programs. The source code programs are transformed into respective intermediate language instructions from which a language-independent control flow graph and a language-independent type environment is created. A program compatible with the interprocedural static code analyzer is generated from the language-independent control flow graph and the language-independent type environment in order to utilize the interprocedural static code analyzer to detect memory safety faults.

Abstract: A code completion system uses neural components to rank the unordered list of code completion candidates generated from an existing static analyzer. The candidates represent the next sequence of tokens likely to complete a partially-formed program element as a developer is typing in a software development tool. A re-ranking component generates a ranked order of the candidates based on a context embedding of the code context and candidate embeddings of the candidates, where both embeddings are based a common token encoding.

Abstract: Provided is a method of preparing chimeric antigen receptor T cells by serum-free culture. The method comprises steps of: (a) providing PBMC cells; (b) performing negative sorting treatment on the PBMC cells to obtain sorted PBMC cells; (c) activating the sorted PBMC cells to obtain activated T cells; (d) transfecting the activated T cells with a viral vector expressing a chimeric antigen receptor, so as to obtain transfected T cells; (e) removing the viruses from the transfected T cells to obtain virus-removed T cells; and (f) subjecting the virus-removed T cells to expansion culture to obtain chimeric antigen receptor T cells.

Abstract: A picture file processing method, apparatus, and computer readable medium are provided. The method includes parsing a picture file, to obtain a picture header information data segment, first stream data, and second stream data of a first image thereof. The first stream data of the first image is decoded to generate red-green-blue (RGB) data of the first image. The second stream data of the first image is decoded to generate Alpha data of the first image. Red-green-blue-alpha (RGBA) data corresponding to the first image are generated according to the RGB data and the Alpha data.

Abstract: In some examples, a method comprises: obtaining, by an artificial reality system including a head mounted display (HMD), image data via an image capture device, the HMD configured to output artificial reality content; detecting, by the artificial reality system, a physical peripheral device from the image data; detecting, by the artificial reality system, a pose of the peripheral device; generating, by the artificial reality system, based on the pose of the peripheral device, a virtual pointer along at least a portion of a line between the peripheral device and a virtual surface, the virtual pointer pointing at a location of the virtual surface; performing, by the artificial reality system, one or more actions based on the location of the virtual surface; and rendering, by the artificial reality system, the virtual pointer and the virtual surface for display at the HMD.

Abstract: The present invention relates to a magnetic navigation-guided tear-away sheath for cardiac conduction bundle pacing, including a sheath body and a joint fixedly connected to a rear end of the sheath body. The sheath body includes a front flexible section and a rear fixed section, and the front flexible section is freely bendable. An outer surface near a head end of the front flexible section is provided with a plurality of pairs of half-ring magnets, two half-ring magnets in each pair of half-ring magnets are symmetrically disposed and form a ring, and a gap is kept between the two half-ring magnets. The head end of the front flexible section is provided with three electrodes uniformly disposed in a circumferential direction, and the three electrodes can be freely combined two by two, to form three electrode pairs used to record and position an intracardiac potential.

Abstract: A method for automatic gain adjustment based on illuminance of video content and a camera are provided. The method includes arranging a first gain value for an image sensor according to a list of preset gain values; obtaining frequency domain data using frequency domain transformation on illuminance components of the image; setting a constant percentage value and summing up the percentage of the frequency domain data accumulated from the highest signal amplitude to obtain a first high frequency information cumulative value; repeating above steps according to a preset gain value arrangement order to obtain a number of high frequency information cumulative values; and using the gain value corresponding to a maximum high frequency information cumulative value in gain adjustment for the image sensor.

Abstract: Automatically recommending sound effects based on visual scenes enables sound engineers during video production of computer simulations, such as movies and video games. This recommendation engine may be accomplished by classifying SFX and using a machine learning engine to output a first of the classified SFX for a first computer simulation based on learned correlations between video attributes of the first computer simulation and the classified SFX.

Abstract: A sustainable pavement is constructed by creating a construction structure for a hot mix asphalt (HMA) pavement according to a pavement project; calculating a greenhouse gas (GHG) emission of the HMA pavement; performing a sustainable construction on the HMA pavement to modify one or more layers in the HMA pavement to form a sustainably constructed pavement; calculating a GHG emission of the sustainably constructed pavement; and obtaining a carbon reduction by comparing the GHG emissions of the HMA pavement and the sustainably constructed pavement.

Abstract: Automatically recommending sound effects based on visual scenes enables sound engineers during video production of computer simulations, such as movies and video games. This recommendation engine may be accomplished by classifying SFX and using a machine learning engine to output a first of the classified SFX for a first computer simulation based on learned correlations between video attributes of the first computer simulation and the classified SFX.

Abstract: The disclosure relates to bacillus having an effect of inducing corn to resist Northern leaf blight and applications of the bacillus. The bacillus having an effect of inducing corn to resist Northern corn leaf blight is Bacillus megaterium which was deposited on Apr. 16, 2019 with a deposit number of CGMCC No. 17573. The Bacillus megaterium of the disclosure can induce corn to generate resistance to Northern corn leaf blight during seed germination and corn growth to activate the immune response of corns and stimulate immune control of Northern leaf blight of corn. The method described herein is long in coming does not pollute environment and soil, is a green, simplified and new control method of Northern leaf blight of corn, and has wide application and popularization prospect.

Abstract: Automatically recommending sound effects based on visual scenes enables sound engineers during video production of computer simulations, such as movies and video games. This recommendation engine may be accomplished by classifying SFX and using a machine learning engine to output a first of the classified SFX for a first computer simulation based on learned correlations between video attributes of the first computer simulation and the classified SFX.

Abstract: Provided is a wire fixing device for a cardiac pacemaker electrodes, including: an electrode fixator having an electrode clamping component, first hooks and second hooks; the electrode clamping component includes a first clamping piece and a second clamping piece that are semicircular cylindrical, the first clamping piece and the second clamping piece are connected by a clamp hinge connector, and a circular tube is formed when the electrode clamping component is closed; first hooks are provided on the back of the first clamping piece, second hooks are provided on the back of the second clamping piece, and hook tips of the first and second hooks are all bent towards a rotation direction of the electrode clamping component during closing; and the first and second hooks can be interlaced with each other when the electrode clamping component is closed, and can be separated when the electrode clamping component is open.

Abstract: A code completion tool uses machine learning models to more precisely predict the likelihood of a method invocation completing a code fragment that follows one or more method invocations of different classes in a same document during program development. In one aspect, the machine learning model is a n-order Markov chain model that is trained on features that represent characteristics of the context of method invocations found in commonly-used programs from a sampled population. The machine learning model is implemented as a hash table contained a ranked order of hash values in descending order of probability of completing a partially-formed method invocation.

Abstract: A deformable high-density and precision balloon cardiac mapping catheter includes a catheter, an electrode head mounted at one end of the catheter, and a handle mounted at the other end of the catheter. A head electrode pair, a middle expansion body and a rear expansion body are sequentially disposed on the electrode head from left to right. A liquid storage apparatus is disposed on a surface of the handle. The liquid storage apparatus includes a reservoir tube. A liquid outlet is disposed at one end of the reservoir tube.

Abstract: Computing systems and technical methods that transform data structures and pierce opacity difficulties associated with complex machine learning modules are disclosed. Advances include a framework and techniques that include: i) global diagnostics; ii) locally interpretable models LIME-SUP-R and LIME-SUP-D; and iii) explainable neural networks. Advances also include integrating LIME-SUP-R and LIME-SUP-D approaches that create a transformed data structure and replicated modeling over local and global effects and that yield high interpretability along with high accuracy of the replicated complex machine learning modules that make up a machine learning application.

Abstract: A domain adaptation module is used to optimize a first domain derived from a second domain using respective outputs from respective parallel hidden layers of the domains.