Patents by Inventor Xiaoyuan Chen

Xiaoyuan Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTISTAGE THICK FILM THERMOELECTRIC DEVICES
    Publication number: 20080178606
    Abstract: The present invention generally provides multistage thermoelectric coolers and methods for their fabrication. For example, in one aspect, a multistage thermoelectric cooler is disclosed that includes at least two cooling stages, each of which comprises a p-type leg portion and an n-type leg portion coupled to form a p-n junction. The p-n junctions of the two stages are thermally and electrically coupled such that at least a portion of a current flowing, during operation of the device, through one stage is coupled to the other. Further, at least one of the p- or n-type leg portions of one stage forms a unitary structure with a corresponding p- or n-type leg portion of the other stage.
    Type: Application
    Filed: January 30, 2007
    Publication date: July 31, 2008
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MIT)
    Inventors: Gang Chen, Xiaoyuan Chen, Ronggui Yang
  • Pet imaging of vascular endothelial growth factor receptor (VEGFR), compositions for VEGF cancer imaging, and methods of VEGF cancer imaging
    Publication number: 20080031815
    Abstract: Briefly described, embodiments of this disclosure include polypeptides, in particular a labeled VEGF protein, kits for imaging, methods for imaging tissue, methods of diagnosing the presence in a tissue of one or more of precancerous cells, cancerous cells, tumor cells, and cells related to ischemic or hypoxic related diseases, methods of monitoring the progress in a tissue of the presence of one or more of precancerous cells, cancerous cells, tumor cells, and cells related to ischemic or hypoxic related diseases, and the like.
    Type: Application
    Filed: July 26, 2007
    Publication date: February 7, 2008
    Inventors: Xiaoyuan Chen, Weibo Cai, Sanjiv Gambhir, Hui Wang, Kai Chen, Martin Rodriguez-Porcel, Juergen Willmann
  • Surface phonon-polariton raman laser
    Publication number: 20070211771
    Abstract: An optical device includes an input optical source that provides and optical signal to the optical device. A surface phonon polariton (SPP) nanostructure receives the optical signal that interacts with the SPP nanostructure to excite a Raman process and produce a Raman light signal. The Raman light signal comprises a broad spectral range from near infrared to far infrared.
    Type: Application
    Filed: March 9, 2006
    Publication date: September 13, 2007
    Inventors: Gang Chen, Xiaoyuan Chen
  • Radionuclide-binding compound, a radionuclide delivery system, a method of making a radium complexing compound, a method of extracting a radionuclide, and a method of delivering a radionuclide
    Patent number: 6117413
    Abstract: The invention pertains to compounds which specifically bind radionuclides, and to methods of making radionuclide complexing compounds. In one aspect, the invention includes a radionuclide delivery system comprising: a) a calix[n]arene-crown-[m]-ether compound, wherein n is an integer greater than 3, and wherein m is an integer greater than 3, the calix[n]arene-crown-[m]-ether compound comprising at least two ionizable groups; and b) an antibody attached to the calix[n]arene-crown-[m]-ether compound.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: September 12, 2000
    Assignees: Battelle Memorial Institute, Idaho Research Foundation, Inc.
    Inventors: Darrell R. Fisher, Chien M. Wai, Xiaoyuan Chen
  • Ion binding compounds, radionuclide complexes, methods of making radionuclide complexes, methods of extracting radionuclides, and methods of delivering radionuclides to target locations
    Patent number: 6075130
    Abstract: The invention pertains to compounds for binding lanthanide ions and actinide ions. The invention further pertains to compounds for binding radionuclides, and to methods of making radionuclide complexes. Also, the invention pertains to methods of extracting radionuclides. Additionally, the invention pertains to methods of delivering radionuclides to target locations. In one aspect, the invention includes a compound comprising: a) a calix[n]arene group, wherein n is an integer greater than 3, the calix[n]arene group comprising an upper rim and a lower rim; b) at least one ionizable group attached to the lower rim; and c) an ion selected from the group consisting of lanthanide and actinide elements bound to the ionizable group.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: June 13, 2000
    Assignees: Battelle Memorial Institute, Idaho Research Foundation, Inc.
    Inventors: Xiaoyuan Chen, Chien M. Wai, Darrell R. Fisher