Abstract: Method and systems for sorting drug-responsive cell population based on single-cell RNA sequencing (scRNA-seq) data are disclosed. In some examples, the method includes: constructing a target gene regulatory network (GRN) for each of the cell populations based on scRNA-seq data of cell populations in a disease state; virtually knocking out targets in the GRN, and constructing a target-perturbed gene regulatory network (tpGRN); acquiring a low-dimensional representation of each of network nodes from the GRN in the GRN and the tpGRN through manifold alignment; calculating a Euclidean distance for each of the network nodes between the GRN and the tpGRN through a Euclidean distance; scoring a drug response of each of the cell populations by comprehensively considering changing trends of a drug target, a 2-hop node, and an edge of the 2-hop node in the GRN and the tpGRN, and determining a sorting result of the drug-responsive cell population.

Abstract: A vilazodone composition, a pharmaceutical preparation thereof, a preparation therefor, and a use thereof, relating to the pharmaceutical field. The composition contains an inclusion compound, the inclusion compound containing an active ingredient wrapped in an inclusion material; and the specification of the pharmaceutical preparation is 8 mg to 9 mg, 16 mg to 18 mg, or 32 mg to 36 mg. Under the condition that the specification of the pharmaceutical preparation can be reduced, the pharmacokinetics effect of the pharmaceutical preparation in a human body can still be equivalent to that of a reference listed drug, and the pharmaceutical preparation has an unexpected technical effect.

Abstract: This application relates to a communication method and a device. The communication method includes: transmitting, by a first device, a first message to a second device, where the first message is used to request at least one of the following operations: downloading application model data or adding application model data; updating application model data or modifying application model data; uploading application model data; or deleting application model data.

Abstract: A transformational energy efficient technology using ionic liquid (IL) to couple with monoethanolamine (MEA) for catalytic CO2 capture is disclosed. [EMmim+][NTF2?] based catalysts are rationally synthesized and used for CO2 capture with MEA. A catalytic CO2 capture mechanism is disclosed according to experimental and computational studies on the [EMmim+][NTF2?] for the reversible CO2 sorption and desorption.

Abstract: Disclosed is an antibody that specifically recognizes and binds to folate receptor ?, also referred to as anti-folate receptor a antibody or anti-FR? antibody. Also disclosed is an antibody-drug conjugate of the anti-FR? antibody. Disclosed are uses of the anti-FR? antibody and the antibody-drug conjugate in the treatment of diseases related to FR? expression.

Abstract: A wireless communication method includes: determining a measurement result of at least one cell; and in a case where a cell whose measurement result meets a corresponding condition exists in the at least one cell, performing, through a layer 1 or a layer 2, any one of: reporting cell quality information of the at least one cell, reporting cell quality information of at least one first candidate cell, and triggering a handover process.

Abstract: A pixel driving circuit, a driving method thereof and a display panel are provided. The pixel driving circuit includes a driving transistor, a capacitor having two terminals connected to a first power terminal and a gate electrode of the driving transistor, and a light emitting device. The pixel driving circuit includes: a reset module; a data writing module; a threshold compensation module including a compensation transistor configured to electrically connect second and gate electrodes of the driving transistor together in the data writing phase; a light emitting control module including a first gating transistor configured to electrically connect the second electrode of the driving transistor and the light emitting device in the reset phase and disconnect the second electrode from the light emitting device in the data writing phase. The compensation transistor and the first gating transistor are oxide transistors, and the driving transistor is a low-temperature polysilicon transistor.

Abstract: The invention pertains to a measuring system for the conductivity of supercritical geothermal fluid, featuring a reaction control unit with a reaction vessel lined with corundum ceramic and containing a stirrer, a pressure control unit including a booster pump connected to Ar gas and an air compressor, a flow control unit with a flowmeter, and a temperature control unit comprising a heating furnace with thermocouples both inside and outside the reaction chamber. An electrical signal monitoring unit with electrodes fitted through a corundum capillary into the ceramic lining measures current and voltage. The invention also details a method for measuring conductivity, highlighting how water-rock interactions in supercritical geothermal fluids affect conductivity changes.

Abstract: An array substrate and a display apparatus are provided The array substrate includes: at least one adjusting portion on the base substrate and having a first cross section in a plane perpendicular to the base substrate; first cross section includes top and bottom sides, first and second lateral sides; the bottom side is closer to the base substrate than the top side, an orthographic projection of the top side on the base substrate is within an orthographic projection of the bottom side on the base substrate; the first and/or second lateral sides is/are stepped; a buffer layer on a side of the adjusting portion away from the base substrate; light-emitting devices on a side of the buffer layer away from the base substrate and each including a first electrode, a light-emitting layer and a second electrode sequentially arranged along a direction away from the base substrate.

Abstract: A display substrate includes a first electrode layer, a pixel define layer, an organic light-emitting layer, a second electrode layer and a first encapsulation layer which are sequentially disposed away from an base substrate. The pixel define layer has a plurality of openings, at least one of which exposes the first electrode layer. The pixel define layer has a first climbing part and a second climbing part close to the edge of at least one opening, the distance from a surface of the second climbing part away from the base substrate to the base substrate is greater than the distance from a surface of the first climbing part away from the base substrate to the base substrate, and the slope angle of the first climbing part is different from that of the second climbing part.

Abstract: Provided is a display panel. The display panel includes a base substrate and a plurality of pixel circuits disposed on the base substrate. At least two pixel circuits in a same column are coupled with a same first initial power line, such that only a small quantity of signal lines need to be disposed on the base substrate.

Abstract: Provided is a method for cell measurement, and a device. The method is applicable to a terminal device. The method includes: performing neighbor cell layer 1 (L1) measurement based on an L1 measurement configuration. The device includes a processor, wherein the processor, when loading and running a computer program, is caused to perform the method for cell measurement.

Abstract: Provided is a display module. The display module includes: a display panel, a first printed circuit board, and a flexible printed circuit board; wherein the display panel is electrically connected to the first printed circuit board, the first printed circuit board is disposed at a back of the display panel, and the flexible printed circuit board includes a first connecting portion, a second connecting portion, and a flexible connecting structure, wherein the flexible connecting structure includes a plurality of stacked connecting bands, two ends of the flexible connecting structure are connected to the first connecting portion and the second connecting portion respectively, the first connecting portion is connected to the first printed circuit board, and the second connecting portion is configured to be connected to the host.

Abstract: The present invention discloses a method for infrared small target detection based on a depth map in a complex scene, and belongs to the field of target detection. An infrared image is collected, the image is binarized by using priori knowledge of a to-be-detected target and adopting a pixel value method, the binary image is further limited based on deep priori knowledge, then static and dynamic scoring strategies are formulated to score a candidate connected component in the morphologically processed image, and an infrared small target in a complex scene is detected finally. The method can screen out targets within a specific range, has high reliability; has strong robustness; is simple in program and easy to implement, can be used in sea, land, and air, and has a significant advantage under a complex jungle background.

Abstract: Systems and methods for determining at least one correction parameter for a Positron Emission Tomography (PET) scanner including a plurality of detector units is provided. For each line of response (LOR) of a plurality of lines of response (LORs) associated with the plurality of detector units, the methods may include determining, based on scan data of one or more scans of a phantom at a plurality of positions, a first sum of coincidence events on the LOR, wherein the phantom is moved to the plurality of positions along an axis of a field of view of the PET scanner during the one or more scans, and a length of the phantom is less than a length of the field of view of the PET scanner along the axis; determining, based on the first sum of coincidence events, at least one correction parameter associated with the LOR.

Abstract: The present invention discloses a method for fully automatically detecting chessboard corner points, and belongs to the field of image processing and computer vision. Full automatic detection of chessboard corner points is completed by setting one or a plurality of marks with colors or certain shapes on a chessboard to mark an initial position, shooting an image and conducting corresponding processing, using a homography matrix H calculated by initial pixel coordinates of a unit grid in a pixel coordinate system and manually set world coordinates in a world coordinate system to expand outwards, and finally spreading to the whole chessboard region.

Abstract: The present disclosure relates to systems and methods for image processing. The method may include obtaining a first image and a second image of a first modality of a target object. The first image may correspond to a first state of the target object, and the second image may correspond to a second state of the target object. The method may include obtaining a third image of a second modality of the target object. The third image may correspond to the first state of the target object. The method may further include determining, based on the first image, the second image, the third image, and an image processing model, a fourth image of the second modality of the target object under the second state.

Abstract: The present invention discloses a disparity estimation optimization method based on upsampling and exact rematching, which conducts exact rematching within a small range in an optimized network, improves previous upsampling methods such as neighbor interpolation and bilinear interpolation for disparity maps or cost maps, and works out a propagation-based upsampling method by the way of network so that accurate disparity values can be better restored from disparity maps in the upsampling process.

Abstract: Systems and methods for determining at least one correction parameter for a Positron Emission Tomography (PET) scanner including a plurality of detector units is provided. For each of the plurality of detector units, the methods may include determining, based on scan data of one or more scans of a phantom at a plurality of positions, a first sum of coincidence events detected by the detector unit. The methods may further include determining a second sum of coincidence events that are expected to be detected by the detector unit and determining, based on the first sum of coincidence events and the second sum of coincidence events, at least one correction parameter associated with the detector unit. The phantom may be moved to the plurality of positions along an axis of a field of view of the PET scanner during the one or more scans.

Abstract: The disclosure relates to the technical field of electric drive assemblies, and in particular provides an electric drive assembly for an electric vehicle, and an electric vehicle. The disclosure provides an electric drive assembly composed of an input shaft integrated with an electric motor rotor and a gearbox first-stage driving gear, three intermediate shafts each integrated with a gearbox first-stage driven gear and a second-stage driving gear, and a differential integrated with a second-stage driven gear. The three intermediate shafts are evenly disposed around the input shaft. The power of the electric motor is transmitted from the first-stage driving gear to the second-stage driven gear on the differential evenly through the three intermediate shafts.