Abstract: The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

Abstract: The present invention discloses a color photoresist and its use, a color film substrate, a display panel and a liquid crystal display, which pertains to the field of photosensitive materials. The color photoresist comprises a photoinitiator and QDs. The photoinitiator is a first photoinitiator containing no electron-rich group or a second photoinitiator containing an electron-rich group. The second photoinitiator comprises a conjugation structure, and the conjugation structure consists of the electron-rich group and an adjacent group of the electron-rich group. The color photoresist provided in embodiments of the present invention contains QDs which emit light normally. The color film substrate prepared by using the color photoresist has a high color gamut and can effectively improve the picture quality of the liquid crystal display.

Abstract: An electrical connector includes an terminal module and a metallic tubular shield fixedly enclosing the terminal module to form a sub-assembly, and a metallic tubular bracket enclosing the sub-assembly. The terminal module includes an insulator having a base and a tongue portion forwardly extending from the base, and a plurality of terminals disposed in the insulator. The base includes a rear end having a securing section, and the bracket has a fixing section correspondingly, wherein the bracket is adapted to be forwardly assembled from a rear side of the sub-assembly to have the fixing section engaged with the securing section.

Abstract: An electrical connector with a terminal module enclosed within an insulative shield wherein the terminal module includes a plurality of terminals embedded within an insulative main body. The insulative main body forms a rear mounting standing part and a front mating tongue part extending forwardly from the rear mounting standing part. The insulative shield forms a rearward step against a forward shoulder of the base portion so as to prevent further forward movement of the base portion relative to the insulative shield. The insulative main body forms a protrusion and the insulative shield forms a securing hole to receive said protrusion for securing the insulative shield and the terminal module together.

Abstract: The present disclosure relates to a system and method for determining an effective electrical resistance in an electronic circuit design. Embodiments may include receiving, at one or more computing devices, an electronic circuit design and identifying one or more features associated with the electronic circuit design. Embodiments may also include performing a resistance only extraction of a circuit net associated with the electronic circuit design and identifying at least two node locations from the electronic circuit as one or more port nodes. Embodiments may further include reducing the resistance only extraction to an equivalent circuit including only the port nodes and attaching a high-resistance ground voltage source to at least one of the port nodes of the reduced equivalent circuit. Embodiments may also include generating a conductance matrix, based upon, at least in part, the reduced equivalent circuit.

Abstract: The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure, kidney disease, edema, and conditions associated with excessive salt and water retention.

Abstract: The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

Abstract: Systems and methods for verifying a digital certificate are provided. According to one embodiment, a network security device intercepts a session between a client and a server, wherein a secure channel is requested to be established between the client and the server in the session. The network security device captures a digital certificate that is being sent from the server to the client, wherein the digital certificate is used for authenticating the server in connection with establishing the secure channel. The network security device verifies the authenticity of the server certificate and performs an action with respect to the session based on a result of the verifying.

Abstract: Systems and methods for verifying a digital certificate are provided. According to one embodiment, a trusted digital certificate of a server is collect by a network security device from a channel. The trusted digital certificate is stored by the network security device within a storage. A digital certificate of the server captured by a certificate inspector is receive by the network security device. The network security device verifies whether the captured digital certificate is an authentic certificate of the server and returns a result of the verification to the certificate inspector.

Abstract: Provided are an optical coupling device and an optical coupling unit including the optical coupling device. The optical coupling device includes a right-angle reflecting prism (23) and a mobile optical fibre connector (21). A reflecting surface of the right-angle reflecting prism (23) is provided with a curve reflecting surface (24), the curve reflecting surface being used for gathering and reflecting rays propagated by an optical fibre. The mobile optical fibre connector (21) is fixed to the right-angle reflecting prism (23), to make the rays propagated by the optical fibre being incident on the curve reflecting surface (24) of the right-angle reflecting prism (23).

Abstract: A display panel, a fabricating method thereof and a display device are provided. The display panel comprises: a first substrate (1); a second substrate (2), opposed to the first substrate (1); a sealant (3), disposed between the first substrate (1) and the second substrate (2) to seal the first substrate (1) and the second substrate (2), and the sealant (3) between adjacent display regions (10,11) between the first substrate (1) and the second substrate (2) including a pre-cutting position (a-a?); and a curing barrier layer (5), disposed at a position corresponding to the pre-cutting position on a surface facing the second substrate (2) of the first substrate (1) and/or on a surface facing the first substrate (1) of the second substrate (2). The sealant (3) covers the curing barrier layer (5). According to the display panel and the fabricating method thereof, the success rate of the sealant (3) break can be increased, and the design of the narrow bezel can be achieved.

Abstract: The present invention relates to compounds of formula (I) that are metallo-?-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with ?-lactam antibiotics for overcoming resistance.

Abstract: Novel spirocyclic compounds of formula I: and pharmaceutically acceptable salts thereof are disclosed as inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention. Pharmaceutical compositions and methods of treatment are also included.

Abstract: An electrochromic structure, a method and a display apparatus. The electrochromic structure includes a display layer including a first substrate (9), a color layer (7) and a second substrate (5); and a background layer including a controllable layer (3) and a third substrate (1); and the display layer is over the background layer. The electrochromic structure has clear hierarchy and simple structure, and can be made into display devices of larger size.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes a pixel unit including first and second sub-unit regions. Liquid crystal molecules in the liquid crystal layer corresponding to the first sub-unit region have a first initial alignment direction, and liquid crystal molecules in the liquid crystal layer corresponding to the second sub-unit region have a second initial alignment direction. The pixel unit further includes a third sub-unit region arranged between the first and second sub-unit regions. Liquid crystal molecules in the liquid crystal layer corresponding to the third sub-unit region have a third initial alignment direction, which is an alignment direction in a rotation from the first initial alignment direction towards the second initial alignment direction along a first rotation direction. An angle difference between the first and second initial alignment directions is greater than 0° and less than or equal to 90°.

Abstract: Embodiments of the present invention disclose a double-faced display panel and a manufacturing method thereof, the double-faced display panel includes: an array substrate, including a first transparent substrate, a first trans-reflective layer formed on the first transparent substrate and a first electrode layer formed on the first trans-reflective layer; an opposed substrate, disposed to face the array substrate, and including a second transparent substrate, a second trans-reflective layer formed on a side of the second transparent substrate facing the first transparent substrate and a second electrode layer formed on a side of the second transparent substrate facing the first transparent substrate; a display structure, disposed between the array substrate and the opposed substrate and including a plurality groups of display units arranged in matrix, wherein each of the first and second trans-reflective layers includes a plurality of reflection regions and a plurality of transmission regions disposed alterna

Abstract: Embodiments of the invention comprise a cholesteric liquid display and a method for preparing the same. The cholesteric liquid display comprises a first substrate; an electrode substrate opposite to the first substrate; and a cholesteric liquid crystal layer between the first substrate and the electrode substrate, wherein the cholesteric liquid crystal layer comprises at least one layer of cholesteric liquid crystal, and the same layer of cholesteric liquid crystal has different pitches in different regions so as to be capable of reflecting light of different colors, respectively.

Abstract: The present disclosure provides a transparent liquid crystal display panel and a transparent liquid crystal display. The transparent liquid crystal display panel includes a backlight module, a color filter substrate and a TFT array substrate which are cell-assembled. Liquid crystal is filled between the color filter substrate and the TFT array substrate. Each pixel unit of the color filter substrate includes a sub-pixel unit and a transparent pixel unit. A region on the TFT array substrate that corresponds to the transparent pixel unit is transparent. A region between the color filter substrate and the TFT array substrate that corresponds to the transparent pixel unit is provided with a transparent resin spacer. A region in the backlight module that corresponds to the transparent pixel unit is a transparent region.

Abstract: An identity management system provides single sign-on (SSO) services to clients, logging the clients into a variety of third-party services for which the clients have accounts. An SSO integration is stored for each of the third-party services, the SSO integration including information that allows the identity management system to automate the login for the corresponding third-party service, such as locations of the login pages, and/or identities of username and password fields. The identity management system uses different techniques in different embodiments to detect that a given SSO integration is broken (i.e., no longer permits login for its corresponding third-party service) and/or to repair the SSO integration.

Abstract: An electrochromic display device comprises: a first electrode substrate; a second electrode substrate; an electrochromic fluid distributed between the first and the second electrode substrate; and a dividing wall located between the first and the second electrode substrate, contacting the first and the second electrode substrate, respectively, and used for isolating the electrochromic fluid into various pixel areas. The electrochromic display device has no interference occurred between adjacent pixel areas. A method for producing such an electrochromic display device is further disclosed.