Abstract: An electronic paper and a manufacturing method thereof are provided. The electronic paper includes a first substrate provided with a microstructure and multiple first electrodes thereon; a second substrate arranged opposite to the first substrate and provided with multiple second electrodes thereon, the microstructure is arranged on a side of the first substrate facing the second substrate; and pixel isolation walls arranged between the first and second substrates, for dividing the electronic paper into pixel units; each pixel unit includes: one first substrate; one second substrate; charged particles arranged between the first and second electrodes, the first and second electrodes control, depending on a voltage applied thereto, contact between the charged particles and the microstructure; when the charged particles are not in contact with the microstructure, light from outside is subject to total internal reflection after being radiated to the microstructure through the first substrate.

Abstract: A display panel and a manufacturing method thereof, and a display device are provided. The display panel includes a plurality of display units. Each display unit includes a first substrate and a second substrate opposite to each other. The first substrate includes a first base substrate and a first electrode, an electrostriction layer and a reflective trough which are disposed thereon. The second substrate includes a second base substrate and a second electrode and a reflective cavity body which are disposed thereon. A support is disposed between the first base substrate and the second base substrate, such that a distance between the first base substrate and the second base substrate is kept constant.

Abstract: In general, the present embodiments are directed to designing an electronic system such as an IC, and more particularly to a design technique that can determine an optimal number and placement of ESD cells in a design for an IC. In embodiments, the technique includes determining an effective resistance criteria between a set of candidate ESD cells to the bumps/pads of the IC and finding a minimum set of ESD cells that covers all the bumps/pads. In embodiments, the technique is employed at the early stage of the design of the IC.

Abstract: A reflective display and a preparation method thereof are disclosed. The reflective display includes: a first substrate and a second substrate, a first electrode provided on the first substrate a transparent dielectric layer provided on a side of the first substrate, which side faces the second substrate, a second electrode provided on the second substrate, and liquid crystal located between the first substrate and the second substrate; a refractive index of the liquid crystal changes under action of an electric field formed by the first electrode and the second electrode so that the refractive index of the liquid crystal is the same as or substantially the same as a refractive index of the transparent dielectric layer, or less than the refractive index of the transparent dielectric layer.

Abstract: The invention relates to methods of identifying compounds that modulate mTORC1 activity in a cell by modulating the activity of SAMTOR, as well as to the use of such identified compounds in the modulation of mTORC1 and the treatment of diseases and conditions characterized by aberrant mTORC1 activity.

Abstract: The disclosure provides a light-adjusting glass, including an outer light transmissive layer and an inner light transmissive layer, a microstructure layer bonded to or disposed on an inner surface of the outer light transmissive layer and provided with a reflective microstructure, a sealing member bonded to an end portion of the outer light transmissive layer and an end portion of the inner light transmissive layer, the sealing member, the microstructure layer and the inner light transmissive layer enclosing a space having a predetermined volume. A predetermined amount of a first substance is disposed within the space. The disclosure also provides a method for preparing a light-adjusting glass. The light-adjusting glass of the present disclosure does not require an electric field to control the light-adjusting.

Abstract: A reflective holographic display apparatus and a display method thereof are disclosed. The reflective holographic display apparatus includes a front light source module, a display panel and a phase plate. The front light source module is configured to provide reference lights; the display panel is configured to adjust amplitude information of the reference lights, wherein the display panel includes a reflective layer and the front light source module is located at a light exit side of the display panel; and the phase plate is configured to adjust phase information of the reference lights and located at a light exit side of the reflective layer.

Abstract: The present disclosure relates to a holographic display apparatus and a method for display by using the same. The holographic display apparatus comprises: a display device, wherein the display device comprises pixels, the pixel contains a light-emitting component, and in each pixel, an amplitude of a light wave emitted from the light-emitting component is independently adjustable; and a phase-controlling plate, wherein the phase-controlling plate is located at a position between the light-emitting component and a light emergence surface of the display apparatus, so that a phase of the light wave emitted from the light-emitting component in each pixel, when the light wave arrives the light emergence surface, is independently adjustable by the phase-controlling plate.

Abstract: A double-sided display panel and a double-sided display device are provided. The double-sided display panel includes a first substrate, a second substrate, a pair of electrodes, and a color display unit, an isolating reflection layer and a black-and-white display unit which are sequentially provided between the first substrate and the second substrate, wherein the color display unit includes an electrochromic material; the black-and-white display unit includes an electrolytic solution, and black particles and white particles having opposite charges dispersed in the electrolytic solution; the isolating reflection layer has properties of allowing ions in the electrolytic solution to permeation and reflecting light. The double-sided display panel has a simple structure and is easy for production, and displays on both sides do not affect each other and bistable display can be achieved.

Abstract: The present invention relates to metallo-?-lactamase inhibitor compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-?-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more ?-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.

Abstract: Disclosed herein are systems and methods to perform electrical analysis of a circuit design to verify electrical behavior and performance of the circuit design in a two-step process. Initially, a simulator transient analysis is performed on circuit blocks of a circuit design to obtain a current through each device path in each circuit block, and using the current obtained the IR drop and EM problems are examined to get EM-IR drop analysis. Next, a simulator transient analysis is performed on a top level circuit of a circuit design and current values generated in a first step to obtain EM-IR drop analysis for a full circuit design such that a circuit designer may debug, analyze and visualize various IR and EM value plots for circuit blocks and top level circuit of the circuit design together or separately.

Abstract: A reflective display includes a first substrate and a second substrate arranged oppositely, a first electrode provided on the first substrate, a transparent dielectric layer arranged on the side of the first substrate opposite to the second substrate, a second electrode provided on the second substrate, and immiscible electrostriction light-absorbing material and transparent liquid filled between the first substrate and the second substrate. The light incident into the reflective display can be totally reflected on the side of the transparent liquid next to the first substrate; the electrostriction light-absorbing material deforms under action of an electric field formed by the first electrode and the second electrode, which enables a spreading area of the side of the transparent liquid next to the first substrate change.

Abstract: A color filter substrate, a display panel and a display device are provided. The color filter substrate includes a base plate and a color filter layer formed on the base plate, a photoluminescent layer arranged at a side of the color filter layer away from the base plate, and a brightness enhancement structure arranged at the side of the color filter layer away from the base plate. In the color filter substrate, by arranging the photoluminescent layer and the brightness enhancement structure at the side of the color filter layer away from the base plate, the color filter substrate has a better color gamut and the brightness at a light-outgoing side is increased.

Abstract: The present disclosure relates to a light-emitting diode (LED), including: a grating layer; and a light reflecting layer, wherein a light-emitting component is disposed between the grating layer and the light reflecting layer; and wherein the grating layer is configured to let linearly polarized light perpendicular to a grating direction of the grating layer in light emitted from the light-emitting component transmit through the grating layer, and reflect linearly polarized light parallel to the grating direction of the grating layer in the light emitted from the light-emitting component.

Abstract: An identity management system detects the occurrence of a trigger event, such as a time period expiration, or an action on the identity management system. The identity management system accordingly generates a new password for an account of a user on a third-party service and causes the account of the user on the third-party service to use the new password. The identity management system can also detect a manual user change of a password for a third-party service and cause configuration of client devices of the user to reflect the new password.

Abstract: Embodiments of the present disclosure provide a light emitting diode, an array substrate, a light emitting device and a display device. The light emitting diode includes an anode, a hole transport layer, a light emitting layer, an electron transport layer, and a cathode sequentially disposed. The light emitting diode further includes a first auxiliary electrode and a first insulating layer which are disposed on a side of the anode away from the hole transport layer, wherein the first insulating layer is located between the first auxiliary electrode and the anode; and/or a second insulating layer and a second auxiliary electrode which are disposed on a side of the cathode away from the electron transport layer, wherein the second insulating layer is located between the second auxiliary electrode and the cathode.

Abstract: The present invention relates to metallo-?-lactamase inhibitor compounds of Formula I: (I) and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and RB are as defined herein. The present invention also relates to compositions which comprise a metallo-?-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more ?-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.

Abstract: The present invention relates to metallo-beta-lactamase inhibitor compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-beta-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta-lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more ?-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.

Abstract: A display panel, a display method thereof and a display device are disclosed. The display panel includes an electrochromic layer (101) and an electrolyte layer (102) arranged in a stacked manner, and at least one kind of colored charged particles (103) being provided in the electrolyte layer (102). While the electrochromic layer (102) is transparent, the display panel displays color of the colored charged particles (103). The display panel may further display the color of the colored charged particles, which increases diversity of the colors displayed by the display panel.

Abstract: The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.