Abstract: The present disclosure provides compounds represented by Formula I-A: A1-L1-B1??I-A and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein A1, B1, and L1 are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I-A for use to treat a condition or disorder responsive to degradation of MDM2 protein such as cancer.

Abstract: The present disclosure provides compounds represented by Formula (I) and the salts or solvates thereof, wherein R3a, E, L, A1, B1, X1, X2, Z1, and Z2 are as defined in the specification. Compounds having Formula (I) are androgen receptor degraders useful for the treatment of cancer and other diseases.

Abstract: Provided are a pump body assembly and an assembly method therefor. The pump body assembly includes a first cylinder assembly (10), a second cylinder assembly (20) and a third cylinder assembly (30) sequentially arranged in a vertical direction. At least one of the first cylinder assembly (10), the second cylinder assembly (20) and the third cylinder assembly (30) is provided with a positioning detection portion (40).

Abstract: A wireless input apparatus is provided, applied to a computer host. The wireless input apparatus includes a wireless dongle and an input module. The wireless dongle is physically connected to the computer host to receive an effect command, and includes a data segmentation unit and a first transceiver unit. The data segmentation unit segments the effect command into a plurality of data segments. The first transceiver unit sequentially transmits the plurality of data segments outwards. The input module includes a second transceiver unit, a merging unit, an effect generation unit, and a control unit. The second transceiver unit is coupled to the first transceiver unit to sequentially receive the plurality of data segments. The merging unit merges the plurality of data segments into the effect command. The control unit receives the effect command, and controls the effect generation unit to generate an effect according to the effect command.

Abstract: A color-mixing lighting control method is used for receiving an original color-mixing light data to control a color-mixing light source. The color-mixing light source includes a plurality of light-emitting elements to produce a plurality of emission colors. The original color-mixing light data includes a plurality of original light intensity values corresponding to the emission colors. The color-mixing lighting control method comprising: determining a maximum value of the original light intensity values; calculating the light intensity percentage of each of the emission colors in the original color-mixing light data according to the original light intensity values; generating the corrected light intensity value of each of the emission colors according to the maximum value and the light intensity percentage of each of the emission colors; and respectively controlling the light-emitting elements by using the corresponding corrected light intensity value of each of the emission colors.

Abstract: A control circuit for an input device including a micro-switch is provided. The control circuit includes an input circuit, a receiver circuit, a control unit, and a detecting unit. The input circuit includes a first contact and a second contact for electrically connecting to the micro-switch. The receiver circuit includes a third contact and a fourth contact for electrically connecting to the micro-switch. The control unit is electrically connected to the first contact and the third contact for providing an input signal via the first contact to the micro-switch and receiving a switching signal from the micro-switch via the third contact. The detecting unit detects a voltage of the second contact to generate a detecting signal. The control unit receives the detecting signal to determine a type of the micro-switch.

Abstract: A cotton topping unmanned aerial vehicle having cutter discs and front grain lifting baffle plates is provided, the unmanned aerial vehicle includes an unmanned aerial vehicle body, a carrying component, a grain lifting component, and a cutting component. The carrying component includes a suspension, an electric push rod mounting base, an electric push rod, a motor mounting base, and motors. An upper end of the electric push rod is bolted to the electric push rod mounting base. The motor mounting base is welded to a lower end of the electric push rod. The grain lifting component is grain lifting baffle plates which include a left baffle plate and a right baffle plate, and both the left baffle plate and the right baffle plate are welded to guard plates.

Abstract: A farmland reference crop evapotranspiration prediction method based on uncertainty of meteorological factors, includes: S1. acquiring a set number of groups of weather forecast data of a prediction region within a preset time period; S2. inputting each group of weather forecast data into a Bayesian probability forecast system to obtain corrected weather forecast data; and S3. inputting each group of the corrected weather forecast data into a trained RBF neural network, and predicting to obtain a farmland reference crop evapotranspiration. In the present invention, the Bayesian probability forecast system is configured to correct the weather forecast data and eliminate uncertainty of weather forecast data to obtain the accurate reference crop evapotranspiration forecasted by the RBF neural network using these data.

Abstract: The present disclosure provides compounds represented by Formula (I): A-L-B (I), and the salts or solvates thereof, wherein A, L, and B are as defined in the specification. Compounds having Formula (I) are androgen receptor degraders useful for the treatment of cancer.

Abstract: A control circuit for an input device including a micro-switch is provided. The control circuit includes an input circuit, a receiver circuit, a control unit, and a detecting unit. The input circuit includes a first contact and a second contact for electrically connecting to the micro-switch. The receiver circuit includes a third contact and a fourth contact for electrically connecting to the micro-switch. The control unit is electrically connected to the first contact and the third contact for providing an input signal via the first contact to the micro-switch and receiving a switching signal from the micro-switch via the third contact. The detecting unit detects a voltage of the second contact to generate a detecting signal. The control unit receives the detecting signal to determine a type of the micro-switch.

Abstract: An optical switch module including a light generation circuit, a light receiving circuit, and a control unit is provided. The light generation circuit includes a light generation unit and a control end, and generates light according to a control signal from the control end. The light receiving circuit includes a light receiving unit and a signal reading end, and is configured to receive light to generate a detection signal at the signal reading end. The control unit is configured to generate the control signal and receive the detection signal. The control unit further selectively configures the signal reading end in an input mode or an output mode. Before the control unit configures the signal reading end in the input mode to read the detection signal, the control unit configures the signal reading end in the output mode to pull up a potential of the light receiving unit.

Abstract: The present disclosure provides compounds represented by Formula I-A: A1-L1-B1 I-A and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein A1, B1, and L1 are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I-A for use to treat a condition or disorder responsive to degradation of MDM2 protein such as cancer.

Abstract: A wireless input apparatus is provided, applied to a computer host. The wireless input apparatus includes a wireless dongle and an input module. The wireless dongle is physically connected to the computer host to receive an effect command, and includes a data segmentation unit and a first transceiver unit. The data segmentation unit segments the effect command into a plurality of data segments. The first transceiver unit sequentially transmits the plurality of data segments outwards. The input module includes a second transceiver unit, a merging unit, an effect generation unit, and a control unit. The second transceiver unit is coupled to the first transceiver unit to sequentially receive the plurality of data segments. The merging unit merges the plurality of data segments into the effect command. The control unit receives the effect command, and controls the effect generation unit to generate an effect according to the effect command.

Abstract: A color-mixing lighting control method is used for receiving an original color-mixing light data to control a color-mixing light source. The color-mixing light source includes a plurality of light-emitting elements to produce a plurality of emission colors. The original color-mixing light data includes a plurality of original light intensity values corresponding to the emission colors. The color-mixing lighting control method comprising: determining a maximum value of the original light intensity values; calculating the light intensity percentage of each of the emission colors in the original color-mixing light data according to the original light intensity values; generating the corrected light intensity value of each of the emission colors according to the maximum value and the light intensity percentage of each of the emission colors; and respectively controlling the light-emitting elements by using the corresponding corrected light intensity value of each of the emission colors.

Abstract: Disclosed are an additive raw material composition and an additive for superhard material product, a composite binding agent, a superhard material product, a self-sharpening diamond grinding wheel and a method for manufacturing the same. The raw material composition consisting of components in following mass percentage: Bi2O3 25%˜40%, B2O3 25%˜40%, ZnO 5%˜25%, SiO2 2%˜10%, Al2O3 2%˜10%, Na2CO3 1%˜5%, Li2CO3 1%˜5%, MgCO3 0%˜5%, and CaF2 1%˜5%. The composite binding agent is prepared from the additive and a metal composite binding agent. The self-sharpening diamond grinding wheel prepared from the composite binding agent has high self-sharpness, high strength, and fine texture, is uniformly consumed during the grinding process, does not need to be trimmed during the process of being used, and maintains good grinding force all the time, fundamentally solving the problems of long trimming time and high trimming cost of the diamond grinding wheel (FIG. 1).

Abstract: Provided are a pump body assembly and an assembly method therefor. The pump body assembly comprises a first cylinder assembly (10), a second cylinder assembly (20) and a third cylinder assembly (30) sequentially arranged in the vertical direction. At least one of the first cylinder assembly (10), the second cylinder assembly (20) and the third cylinder assembly (30) is provided with a positioning detection portion (40).

Abstract: The present disclosure provides compounds represented by Formula I: and the salts or solvates thereof, wherein X, L, Y, and B are as defined in the specification. Compounds having Formula I are immunomodulators and/or monofunctional synthetic intermediates that can be used to prepare small-molecule drug conjugates.

Abstract: The present disclosure provides compounds represented by Formula I: and the salts or solvates thereof, wherein X, L, Y, and B are as defined in the specification. Compounds having Formula I are immunomodulators and/or monofunctional synthetic intermediates that can be used to prepare small-molecule drug conjugates.

Abstract: Disclosed are an additive raw material composition and an additive for superhard material product, a composite binding agent, a superhard material product, a self-sharpening diamond grinding wheel and a method for manufacturing the same. The raw material composition consisting of components in following mass percentage: Bi2O3 25%˜40%, B2O3 25%˜40%, ZnO 5%˜25%, SiO2 2%˜10%, Al2O3 2%˜10%, Na2CO3 1%˜5%, Li2CO3 1%-5%, MgCO3 0%˜5%, and CaF2 1%˜5%. The composite binding agent is prepared from the additive and a metal composite binding agent. The self-sharpening diamond grinding wheel prepared from the composite binding agent has high self-sharpness, high strength, and fine texture, is uniformly consumed during the grinding process, does not need to be trimmed during the process of being used, and maintains good grinding force all the time, fundamentally solving the problems of long trimming time and high trimming cost of the diamond grinding wheel (FIG. 1).

Abstract: Disclosed are an additive raw material composition and an additive for superhard material product, a method for preparing the additive, a composite binding agent, a superhard material product, a self-sharpening diamond grinding wheel and a method for manufacturing the same. The raw material composition consisting of components in following mass percentage: Bi2O3 25%˜40%, B2O3 25%˜40%, ZnO 5%˜25%, SiO2 2%˜10%, Al2O3 2%˜10%, Na2CO3 1%˜5%, Li2CO3 1%˜5%, MgCO3 0%˜5%, and CaF2 1%˜5%. The composite binding agent is prepared from the additive and a metal composite binding agent. The self-sharpening diamond grinding wheel prepared from the composite binding agent has high self-sharpness, high strength, and fine texture, is uniformly consumed during the grinding process, does not need to be trimmed during the process of being used, and maintains good grinding force all the time, fundamentally solving the problems of long trimming time and high trimming cost of the diamond grinding wheel.