Patents by Inventor Xin Jiang

Xin Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRAZOLYL AND PYRIMIDINYL TRICYCLIC ENONES AS ANTIOXIDANT INFLAMMATION MODULATORS
    Publication number: 20140051739
    Abstract: Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.
    Type: Application
    Filed: July 11, 2013
    Publication date: February 20, 2014
    Inventors: Eric ANDERSON, Gary L. BOLTON, Bradley CAPRATHE, Xin JIANG, Chitase LEE, William H. ROARK, Melean VISNICK
  • ANTIOXIDANT INFLAMMATION MODULATORS: OLEANOLIC ACID DERIVATIVES WITH AMINO AND OTHER MODIFICATIONS AT C-17
    Publication number: 20130317007
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: April 11, 2013
    Publication date: November 28, 2013
    Applicant: Reata Pharmaceuticals, Inc.
    Inventors: Eric ANDERSON, Xin JIANG, Melean VISNICK
  • ELECTRONIC BOOK CONTENT PROTECTION
    Publication number: 20130283384
    Abstract: A system and method are disclosed for protecting an electronic book from unauthorized access. HTML for the book is shredded by dividing it into portions, and a selection scheme is used to intersperse decoy data among the portions. Dynamically generated cascading style sheets are used to define a pattern for decoy and content data such that a browser on a client device correctly processes the HTML but an unauthorized program such as a web scraper cannot correctly process the HTML.
    Type: Application
    Filed: April 23, 2012
    Publication date: October 24, 2013
    Applicant: GOOGLE INC.
    Inventors: Xin Jiang, Shawn Brenneman
  • Dustproof electrical connector assembly
    Patent number: 8545242
    Abstract: An electrical connector assembly (100) includes an electrical connector (1), a cage (5) defining an opening (51), an ejection mechanism (3) assembled on an electrical device and receiving the electrical connector, and a flexible circuit board (2) connecting the electrical connector with a mother board of the electrical device for signal transmission. The ejection mechanism has a second housing (7) retractively movably relative to the first housing to extend through the opening of the cage. The electrical connector is received in the second housing such that the electrical connector is movable out of the electrical device for connecting with a mating connector and retractable in the electrical device when the electrical connector is not in use.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: October 1, 2013
    Assignee: Hon Hai Precision Industry Co., Ltd.
    Inventors: Han-Ming Zhang, Jian-Xin Jiang
  • Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators
    Patent number: 8513436
    Abstract: Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: August 20, 2013
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Eric Anderson, Gary L. Bolton, Bradley Caprathe, Xin Jiang, Chitase Lee, William H. Roark, Melean Visnick
  • Double balanced mixer
    Patent number: 8498604
    Abstract: An improved double balanced mixer is provided which in one embodiment includes a first balun for receiving a first single input and providing a first balanced output having two ports, a second balun for receiving a second single input and providing a second balanced output having two ports, and a balanced mixer core responsive to the first and second balanced outputs to provide a mixed signal from the first and second single inputs. The first balun includes an RC network coupled between at least one of the ports of the first balanced output and one of ground and a common mode node of the first balun to improve the linearity of the double balanced mixer.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: July 30, 2013
    Assignee: Hittite Microwave Corporation
    Inventors: Xin Jiang, Michael Koechlin
  • Screening methods involving the detection of short-lived proteins
    Patent number: 8460876
    Abstract: A method is provided for screening for agents that affect protein degradation rates, the method comprising: taking a library of cells, the cells expressing a fusion protein comprising a reporter protein and a protein encoded by a sequence from a cDNA library derived from a sample of cells, the sequence from the cDNA library varying within the cell library; contacting the library of cells with a plurality of agents which may affect protein degradation rates; for each agent, selecting cells in the library which express short-lived proteins based on whether the cells have different reporter signal intensities than other cells in the library, the difference being indicative of the selected cells expressing shorter lived fusion proteins than the fusion proteins expressed by the other cells in the library; and characterizing the fusion proteins expressed by the selected cells for each agent.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: June 11, 2013
    Assignee: Affymetrix, Inc.
    Inventors: Xianqiang Li, Xin Jiang
  • Antioxidant inflammation modulators: oleanolic acid derivatives with amino acid and other modifications at C-17
    Patent number: 8440854
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: May 14, 2013
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Eric Anderson, Xin Jiang, Melean Visnick
  • Antioxidant inflammation modulators: oleanolic acid derivatives with saturation in the C-ring
    Patent number: 8440820
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: May 14, 2013
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Eric Anderson, Xin Jiang, Xiaofeng Liu, Melean Visnick
  • BABY MONITORING MAT BASED ON FIBER OPTIC SENSOR
    Publication number: 20130109931
    Abstract: The present invention provides a baby monitoring mat having a sensor mat having a top mesh layer, a bottom mesh layer, and two flexible sheets and an optical cable, wherein the optical cable is routed across and sandwiched in between the top mesh layer and the bottom mesh layer, and the flexible sheets further sandwiched the top mesh layer and the bottom mesh layer in between forming sensing area across the flexible sheet surface; a light source for feeding light from one side of the optical cable; a photodiode for detecting light attenuation at the other end of the optical cable; a printed circuit board having a processor connected to the light source and the photodiode, wherein the processor operationally receives signals from the photodiode, the signals are processed to determine movements and breath counts.
    Type: Application
    Filed: March 3, 2011
    Publication date: May 2, 2013
    Applicant: Excelpoint Technology Limited
    Inventors: Seng Tat Ng, Xin Jiang, Hwee Siong Chong
  • Alpha5-beta1 antibodies and their uses
    Patent number: 8399647
    Abstract: The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin ?5?1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-?5?1 antibodies or antigen binding portions thereof described herein.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: March 19, 2013
    Assignees: Pfizer Inc., Bristol-Myers Squibb Company
    Inventors: Steven L. Bender, Gerald F. Casperson, Dana D. Hu-Lowe, Xin Jiang, Gang Li, Michael A. North, Jianying Wang, Grant Wickman, Peter Brams, Haichun Huang, Brigitte Devaux, Haibin Chen, Dawn M. Tanamachi, Kristopher Toy, Lan Yang, Tim W. Sproul, Mark Yamanaka
  • Antioxidant inflammation modulators: C-17 homologated oleanolic acid derivatives
    Patent number: 8394967
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: March 12, 2013
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Antioxidant inflammation modulators: novel derivatives of oleanolic acid
    Patent number: 8338618
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: December 25, 2012
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • COMPOUNDS INCLUDING AN ANTI-INFLAMMATORY PHARMACORE AND METHODS OF USE
    Publication number: 20120283450
    Abstract: This invention provides novel compounds comprising the following anti-inflammatory pharmacore: wherein X, R1 and R2 are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: July 18, 2012
    Publication date: November 8, 2012
    Inventors: Eric Anderson, Gary L. Bolton, Deborah A. Ferguson, Xin Jiang, Robert M. Kral, JR., Patrick M. O'Brien, Melean Visnick
  • DUSTPROOF ELECTRICAL CONNECTOR ASSEMBLY
    Publication number: 20120264313
    Abstract: An electrical connector assembly (100) includes an electrical connector (1), a cage (5) defining an opening (51), an ejection mechanism (3) assembled on an electrical device and receiving the electrical connector, and a flexible circuit board (2) connecting the electrical connector with a mother board of the electrical device for signal transmission. The ejection mechanism has a second housing (7) retractively movably relative to the first housing to extend through the opening of the cage. The electrical connector is received in the second housing such that the electrical connector is movable out of the electrical device for connecting with a mating connector and retractable in the electrical device when the electrical connector is not in use.
    Type: Application
    Filed: April 12, 2012
    Publication date: October 18, 2012
    Applicant: HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: HAN-MING ZHANG, JIAN-XIN JIANG
  • C4 Monomethyl Triterpenoid Derivatives and Methods of Use Thereof
    Publication number: 20120252776
    Abstract: Disclosed herein are novel C4-monomethyl triterpenoid compounds and derivatives thereof, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example as antioxidant inflammation modulators, and compositions thereof are also provided.
    Type: Application
    Filed: March 12, 2012
    Publication date: October 4, 2012
    Inventors: Eric Anderson, Christopher F. Bender, Xiaofeng Liu, Xin Jiang, Melean Visnick
  • Antioxidant Inflammation Modulators: Oleanolic Acid Derivatives with Saturation in the C-Ring
    Publication number: 20120245374
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: January 11, 2012
    Publication date: September 27, 2012
    Applicant: REATA PHARMACEUTICALS, INC.
    Inventors: Eric Anderson, Xin Jiang, Xiaofeng Liu, Melean Visnick
  • ANTIOXIDANT INFLAMMATION MODULATORS: NOVEL DERIVATIVES OF OLEANOLIC ACID
    Publication number: 20120238767
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Application
    Filed: November 11, 2011
    Publication date: September 20, 2012
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • Dehydroandrosterone analogs including an anti-inflammatory pharmacore and methods of use
    Patent number: 8258329
    Abstract: This invention provides novel compounds comprising the following anti-inflammatory pharmacore: wherein X, R1 and R2 are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: September 4, 2012
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Eric Anderson, Gary L. Bolton, Deborah A. Ferguson, Xin Jiang, Robert M. Kral, Jr., Patrick M. O'Brien, Melean Visnick
  • ANTIOXIDANT INFLAMMATION MODULATORS: OLEANOLIC ACID DERIVATIVES WITH AMINO ACID AND OTHER MODIFICATIONS AT C-17
    Publication number: 20120214814
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: January 23, 2012
    Publication date: August 23, 2012
    Inventors: Eric Anderson, Xin Jiang, Melean Visnick