Abstract: A calculation system for predicting a proppant embedding depth based on a shale softening effect is provided, including a sampling test terminal, a scheduling module, a monitoring module, and a calculation module, wherein the scheduling module, the monitoring module, and the calculation module are connected in communication, and the monitoring module is connected to an external operating system through a wireless network, wherein the external operating system is configured to perform a hydraulic fracturing operation and receive a first control signal and/or a second control signal from the monitoring module. The sampling test terminal is configured to test the samples and obtain test data. The scheduling module is configured to determine a target construction parameter.

Abstract: Disclosed are a new AXL-targeting monoclonal antibody and antibody-drug conjugate. Also disclosed is a method for preparing said antibody and antibody-drug conjugate. The AXL antibody of the present invention can bind with purified human AXL protein and multiple AXL on tumor cell surface with high effectiveness and high specificity. Said humanized antibody also has high affinity and low immunogenicity. Said AXL antibody-drug conjugate has markable performance against tumors having high AXL expression.

Abstract: The audio playing method is provided by embodiments of the present disclosure, applied to on-board audio system (including multiple speaker modules arranged at different positions in a car cabin, the audio playing method includes: obtaining an audio signal to be played; decomposing the audio signal to obtain multiple audio source signals of different categories, where each of the multiple sound source signals includes multiple sub sound source signals of a same category; establishing a route between all sub sound source signals and the multiple speaker modules according to a preset distribution principle indicating rules for playing different sub sound source signals by different speaker modules; and playing each of the multiple sub sound source signals by a corresponding speaker module according to the route. The present disclosure provides more accurate and immersive car multi-channel surround sound playback, which can effectively improve overall acoustic experience of the on-board audio system.

Abstract: A method of a polyurethane foam includes the following steps of: (1) simultaneously pumping a mixed solution prepared from hydrogen peroxide, an organic acid, a catalyst and a stabilizer and a vegetable oil into a first microstructured reactor of a micro-channel modular reaction device for reacting to obtain a reaction solution containing epoxidized vegetable oil; (2) simultaneously pumping the reaction solution containing the epoxidized vegetable oil obtained from the step (1) and a compound of formula III into a second microstructured reactor of the micro-channel modular reaction device for reaction to obtain a vegetable oil polyol; and (3) reacting the vegetable oil polyol prepared from the step (2) with a foam stabilizer, a cyclohexylamine, an isocyanate and a foaming agent cyclopentane for foaming so as to prepare a rigid polyurethane foam.

Abstract: Provided herein are methods and related apparatus for depositing an ashable hard mask (AHM) on a substrate by providing a wide gap electrode spacing in low-pressure conditions. A wide gap electrode may facilitate control of parasitic plasmas in low-pressure conditions, thereby enabling formation of high selectivity, low stress, and low-hydrogen AHMs. The AHM may then be used to etch features into underlying layers of the substrate.

Abstract: A channel measurement method includes: receiving a plurality of reference signals in a plurality of first frequency domain units in a same time domain unit, where the plurality of reference signals may be respectively precoded by using precoding matrices corresponding to the first frequency domain units in which the plurality of reference signals are located, and precoding matrices corresponding to at least two different first frequency domain units in the plurality of first frequency domain units are different; generating a precoding matrix indicator (PMI) based on the plurality of reference signals, where the PMI indicates a plurality of codewords corresponding to a plurality of second frequency domain units, the plurality of second frequency domain units and the plurality of first frequency domain units belong to a same frequency domain resource, and the plurality of codewords may be used for determining a downlink channel; and sending the PMI.

Abstract: Systems and methods are provided for acquiring training data and building an organizational-based language model based on the training data. In organizational data is generated via one or more applications associated with an organization, the collected organizational data is aggregated and filtered into training data that is used for training an organizational-based language model for speech processing based on the training data.

Abstract: Provided is a system and method for acquiring training data and building an organizational-based language model based on the training data. In one example, the method may include collecting organizational data that is generated via one or more applications associated with an organization, aggregating the collected organizational data with previously collected organizational data to generate aggregated organizational training data, training an organizational-based language model for speech processing based on the aggregated organizational training data, and storing the trained organizational-based language model.

Abstract: Provided is a system and method for acquiring training data and building an organizational-based language model based on the training data. In one example, the method may include collecting organizational data that is generated via one or more applications associated with an organization, aggregating the collected organizational data with previously collected organizational data to generate aggregated organizational training data, training an organizational-based language model for speech processing based on the aggregated organizational training data, and storing the trained organizational-based language model.

Abstract: In a fluoro-TF-MUC1 glycopeptide conjugate, a glycopeptide has a clear and single chemical structure, and can be synthesized in large quantities by chemical methods. The linker selected is easy to be activated, which can be coupled with a carrier protein with high efficiency, and improve the glycoprotein load of the carrier protein. The introduction of fluorine atoms can enhance the stability of glycosidic bonds in glycopeptide antigens, thereby improving the metabolic stability, fat solubility and bioavailability of glycopeptide antigens, and solving the problems of poor immunogenicity and instability of natural tumor-associated MUC1 glycopeptide. Enzyme-linked immunoassay (ELISA) shows that the antibodies in the serum after immunization can recognize the natural MUC1 and achieve cross recognition.

Abstract: System and methods for identifying pulmonary arteries and veins and creating three-dimensional models of pulmonary arteries and veins. This invention helps lung surgical planning and quantitative analyses of the vessel relevant diseases and the study of vascular alternations, which may serve as biomarkers for other diseases (e.g., COPD or pulmonary hypertension) and their progressions.

Abstract: An EnodeB or a transmitting device intermittently generates synchronization signals, and then performs perfect omnidirectional pre-coding processing on the synchronization signals; the synchronization signals after perfect omnidirectional pre-coding processing pass through a transmission channel and are then received by a mobile terminal or a receiving device, and the mobile terminal or the receiving device uses the received synchronization signals and local replicas of the synchronization signals for receiving and synchronization processing. An EnodeB or a transmitting device generates vector signals via low-dimensional space-time coding, and then performs perfect omnidirectional pre-coding processing on the vector signals; the transmitted signals after perfect omnidirectional pre-coding processing pass through a transmission channel and are then received by a mobile terminal or a receiving device, and the mobile terminal or the receiving device uses the received signals for signal receiving processing.

Abstract: Provided is a system and method for acquiring training data and building an organizational-based language model based on the training data. In one example, the method may include collecting organizational data that is generated via one or more applications associated with an organization, aggregating the collected organizational data with previously collected organizational data to generate aggregated organizational training data, training an organizational-based language model for speech processing based on the aggregated organizational training data, and storing the trained organizational-based language model.

Abstract: An EnodeB or a transmitting device intermittently generates synchronization signals, and then performs perfect omnidirectional pre-coding processing on the synchronization signals; the synchronization signals after perfect omnidirectional pre-coding processing pass through a transmission channel and are then received by a mobile terminal or a receiving device, and the mobile terminal or the receiving device uses the received synchronization signals and local replicas of the synchronization signals for receiving and synchronization processing. An EnodeB or a transmitting device generates vector signals via low-dimensional space-time coding, and then performs perfect omnidirectional pre-coding processing on the vector signals; the transmitted signals after perfect omnidirectional pre-coding processing pass through a transmission channel and are then received by a mobile terminal or a receiving device, and the mobile terminal or the receiving device uses the received signals for signal receiving processing.

Abstract: This Application pertains to a charging control method including: setting a temperature range when a wearable electronic device is being charged according to a user demand; when the charging starts, turning on a wirelessly receiving coil of the wearable electronic device and using it to generate a charging current for charging the wearable electronic device; when it is monitored that a value of the charging current of the wearable electronic device rises to a preset constant-current charging current value, acquiring in real time a temperature value of the wearable electronic device; and judging whether the temperature value is within the temperature range; and if yes, maintaining the present value of the charging current of the wearable electronic device; and if not, changing the value of the charging current of the wearable electronic device, so that the temperature value of the wearable electronic device is within the temperature range.

Abstract: The present disclosure relates to a 2,4-disubstituted pyrimidine derivative and the use thereof as a therapeutically effective cyclin-dependent kinase (CDK) inhibitor. In particular, the present disclosure relates to the use of a new 2,4-disubstituted pyrimidine derivatives shown in formula (I) and a pharmaceutical composition thereof as a selective CDK4/6 inhibitor in preventing or treating diseases related to CDK4/6.

Abstract: The present invention relates to a heterocyclic-substituted pyridinopyrimidinone derivative and the use thereof as a therapeutically effective cyclin-dependent kinase (CDK) inhibitor. In particular, the present invention relates to the use of a new heterocyclic-substitute pyridinopyrimidinone derivative as shown in formula (I) and a pharmaceutical composition thereof as a selective CDK4/6 inhibitor in preventing or treating diseases related to CDK4/6.

Abstract: Described herein is an omni-directional transmission scheme allowing signals to transmit from a base station to multiple users in massive MIMO systems with reduced pilot overhead and system complexity. The transmission scheme uses a low-dimensional space-time coding scheme to generate a K-dimensional vector signal, and based on the K-dimensional vector signal, using an omni-directional precoding matrix W to generate an M-dimensional vector signal for transmission over a large number of transmitting antennas, wherein the matrix W comprises M rows and K columns, and K is much smaller than M.

Abstract: The present disclosure relates to a 2,4-disubstituted pyrimidine derivative and the use thereof as a therapeutically effective cyclin-dependent kinase (CDK) inhibitor. In particular, the present disclosure relates to the use of a new 2,4-disubstituted pyrimidine derivatives shown in formula (I) and a pharmaceutical composition thereof as a selective CDK4/6 inhibitor in preventing or treating diseases related to CDK4/6.

Abstract: The present invention relates to a heterocyclic-substituted pyridinopyrimidinone derivative and the use thereof as a therapeutically effective cyclin-dependent kinase (CDK) inhibitor. In particular, the present invention relates to the use of a new heterocyclic-substitute pyridinopyrimidinone derivative as shown in formula (I) and a pharmaceutical composition thereof as a selective CDK4/6 inhibitor in preventing or treating diseases related to CDK4/6.