Abstract: A photolithography machine with an alignment system is described. The photolithography machine can identify a fiducial pattern provided on a substrate and use the location of the fiducial pattern to align the substrate before exposure. The fiducial pattern can include a plurality of fiducial markings arranged in a specified pattern. A model matching technique can be applied to match the respective individual fiducial markings. A shaping technique can then be used to identify the fiducial pattern based on the matched fiducial markings.

Abstract: Disclosed are assays for ultra-fast exponential isothermal amplification of nucleic acids. The assays can improve target detection specificity by using three adjacent binding sites on the target sequence, compared to just one trigger sequence in conventional EXPAR, to initiate the exponential amplification reaction. Amplification of an EXPAR trigger sequence can be carried out via a two-stage process, wherein a first stage achieves linear amplification of the trigger sequence upon successful detection of three adjacent binding sites specified on the target nucleic acid, followed by a second stage that achieves subsequent exponential amplification.

Abstract: A device and a method for recovering by-product oxygen from water-electrolysis hydrogen production using a low-temperature method are provided, solving the waste problem of by-product oxygen in the green water-electrolysis hydrogen production system. The device according to the present disclosure comprises an oxygen clarifying system, a pressurizing and heat exchanging system, and a circulating gas compression and expansion refrigeration system. The recovering method according to the present disclosure comprises the following steps: first clarifying and purifying the by-product oxygen from water-electrolysis hydrogen production is to remove hydrogen, carbon monoxide, carbon dioxide, water and other impurities in the oxygen; and then, liquefying, pressurizing and heat exchanging the pure oxygen to obtain the product oxygen and liquid oxygen with required pressure. In the whole process, the cooling capacity is provided by the circulating gas expansion refrigeration system.

Abstract: A non-acidified fermented dairy product and a preparation method thereof are provided, relating to the technical field of fermented dairy products processing. The preparation method of the non-acidified fermented dairy product includes: inoculating a fermentation inoculum into cow milk, and performing a two-stage fermentation to obtain the non-acidified fermented milk; wherein the two-stage fermentation comprises a first-stage fermentation and a second-stage fermentation; a rotation speed of the first-stage fermentation is 180-250 revolutions per minute, and a duration is 10-20 hours; a rotation speed of the second-stage fermentation is 100-160 revolutions per minute, and a duration is 8-16 hours.

Abstract: A method for lowering cholesterol and lipid levels using the Antrodia cinnamomea water-insoluble dietary fiber prepared as herein. After ethanol and water extraction, Antrodia cinnamomea wastes are dried and superfine-comminuted to obtain Antrodia cinnamomea waste powder. The waste powder treated with NaOH solution containing NaBH4 is extracted it twice to obtain two extracts. The two extracts are combined and an appropriate amount of glacial acetic acid are added for neutralization. The extracts are centrifugalized and precipitate is collected. After washing the precipitate with ultrapure water, the precipitate is dissolved with LiCl-DMSO. The precipitate that is insoluble in the LiCl-DMSO solution is dialyzed and freeze-dried to obtain the water-insoluble dietary fiber component ACA-IDK of Antrodia cinnamomea. The LiCl-DMSO solution is subjected to ethanol/DMSO fractional precipitation, and then the precipitate is collected and dialyzed.

Abstract: A preparation method of Antrodia cinnamomea water-insoluble dietary fiber. After ethanol and water extraction, Antrodia cinnamomea wastes are dried and superfine-comminuted to obtain Antrodia cinnamomea waste powder. The waste powder treated with NaOH solution containing NaBH4 is extracted it twice to obtain two extracts. The two extracts are combined and an appropriate amount of glacial acetic acid are added for neutralization. The extracts are centrifugalized and precipitate is collected. After washing the precipitate with ultrapure water, the precipitate is dissolved with LiCl-DMSO. The precipitate that is insoluble in the LiCl-DMSO solution is dialyzed and freeze-dried to obtain the water-insoluble dietary fiber component ACA-IDK of Antrodia cinnamomea. The LiCl-DMSO solution is subjected to ethanol/DMSO fractional precipitation, and then the precipitate is collected and dialyzed. The water-insoluble dietary fiber component ACA-DK of Antrodia cinnamomea is obtained after freeze-drying.

Abstract: Disclosed are a system and method for enhancing the visualization, classification, and/or interpretation of a photonic readout of a colorimetric assay. The colorimetric assay is associated with a defined color spectrum that includes a positive region indicative of positive test results and a negative region indicative of negative test results. The system and method operate to receive an image of the photonic readout, convert the image to a predefined color space, enhance image saturation and hue, and adjust a brightness level of the image. The system and method increase visual contrast between the negative and positive regions of the color spectrum specific to the colorimetric assay, making the readout easier to interpret for both users with normal vision and users with variations of color weakness or blindness.

Abstract: Pseudomonas and a use thereof are provided. The preservation number of the Pseudomonas is CGMCC No. 22583. The growth temperature of the Pseudomonas is 37-45° C. Under a medium-high temperature oil reservoir condition, the Pseudomonas can be denatured from a non-viscosity fluid to a multifunctional oil-extraction bacterial solution having both surface activity and viscoelasticity, and also has the functions of expanding the swept volume and improving the oil washing efficiency. The recovery ratio is increased by more than 20% in a physical simulation experiment.

Abstract: A system may port a data model into a strict schema system, translate the data model into a transformation rule definition, fit the transformation rule definition to a transform action, receive strict schema data, perform the transform action on the strict schema data based on the transformation rule definition to form rough data, and execute filtering and enriching operations on the rough data to form loose schema data.

Abstract: Systems and methods for improving substrate fabrication are provided. Subsets of dies of substrates may be inspected at various points in the fabrication process to generate spectra data. The spectra data can be used to generate data that are input to a machine learning model to predict yields for the substrates.

Abstract: Proactive management of semiconductor substrate tools. A machine learning model is used to predict future performance characteristics for such tools. In some examples, the model can diagnose issues with tools or with ambient conditions of the tools' environment. In some examples, the model can recommend one or more remedial actions to maintain adequate performance of the substrate tool.

Abstract: Systems and methods for identifying and classifying defects in a manufactured article, such as an article containing a semiconductor substrate, are provided. Inspection data generated by an inspection tool inspecting the manufactured article is used to generate a defect map. The defect map includes an arrangement of potential defect indicators. Thresholding is performed between potential defect indicators, removing, based on the dynamic thresholding, a subset of the potential defect indicators from the arrangement to generate a modified defect map. Based on the modified defect map, a defect can be identified and classified.

Abstract: Provided in the present disclosure are an emoji display method and apparatus, and a device and a storage medium. The emoji display method provided in the present disclosure comprises: displaying at least one preset masked icon on an input panel of a conversation interface; and displaying a first emoji in a first emoji set on the input panel, responsive to a triggering on the preset masked icon, to switch the preset masked icon.

Abstract: A method for community search is performed by an electronic device. The method includes: obtaining graph data to be processed, in which the graph data includes a plurality of nodes and a plurality of connection edges between the nodes; determining a query node from the plurality of nodes based on the graph data, and determining a target community to which the query node belongs by performing a community search for the query node, in which the target community includes the query node, and at least one node other than the query node in the plurality of nodes; and determining the query node and performing the community search for the query node repeatedly until the community to which each node included in the graph data belongs is determined.

Abstract: A multi-specific antibody targeting BCMA. Specifically provided are a multi-specific antibody, a nucleic acid encoding same, a vector including the nucleic acid, a cell including the vector, and a pharmaceutical composition including same. Further provided is the use thereof for treating a subject having a disease related to BCMA expression.

Abstract: The present disclosure provides compositions and methods related to the detection of pathogenic organisms. In particular, the present disclosure provides compositions and methods related to the detection and/or quantification of viral RNA in a sample from a subject that has, or is suspected of having, a SARS-COV-2 infection. Using rapid reverse-transcription loop-mediated isothermal amplification (RT-LAMP), the compositions and methods of the present disclosure provide a portable, inexpensive, rapid, and accurate assay platform for detecting and/or quantifying the presence of a pathogenic organism (e.g., SARS-COV-2) in a patient sample.

Abstract: Provided is a method for lowering a temperature in thermal remediation of contaminated soil, which belongs to the field of soil and groundwater contamination control technologies. In the present disclosure, the method includes the following steps: injecting an entrainer into petroleum hydrocarbons (PHCs) contaminated soil to be remediated to allow soil remediation by thermal desorption; where the entrainer includes ethanol at a volume percentage of 10% to 50%.

Abstract: A system and/or method of detecting a defect in a manufactured article. Images of the manufactured article are generated having different imaging attributes from one another. A multi-channel image is constructed using the images, each image channel of the multi-channel image corresponding to one of the images. The multi-channel image is input to a processor, which determines, based on the input. at least whether the manufactured article includes a defect.

Abstract: A water and gas dual-purpose electric erection aid includes a vacuum barrel and a device bin, which has a seal cover that covers one end of the vacuum barrel and a pump valve pipeline mechanism arranged in the seal cover and used for vacuumizing the vacuum barrel; the device bin is installed with a button control assembly via a support frame; the seal cover is provided with an open groove exposing a button part of the button control assembly and the open groove is tightly attached to the button control assembly; the pump valve pipeline mechanism is communicated with two connection ports formed at the top of the vacuum barrel and a vent cover fixedly arranged on the seal cover through a connecting pipe. The erection aid can be used both in air and underwater. It has good adjuvant treatment and improvement effects on men suffering from sexual dysfunction.

Abstract: Disclosed herein are methods, compositions, and kits for rapid molecular diagnostics that integrate sample processing (including sample inactivation, sample lysis, nucleases inhibition, nucleic acid extraction, nucleic acid stabilization), nucleic acid amplification, and result readout into a single unified-one-pot reaction, enabling the molecular assay to be completed with minimal steps inside a single reaction vessel.