Patents by Inventor Xing Chen

Xing Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230150947
    Abstract: A pyrimidine-2,4-diamine compound and a preparation method and application thereof are provided. The pyrimidine-2,4-diamine compound of the present disclosure can be used in the research of biological or pharmacological phenomena and cathepsin C-involved signal pathway transduction and the evaluation of novel cathepsin C inhibitors. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-cathepsin C activity in vitro and in vivo and proved to have strong inhibitory activity on cathepsin C. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-NSP activity in vivo and proved to have strong inhibitory activity on NSP. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-inflammatory activity in vivo and proved to have an effective therapeutic effect on inflammatory disease models. Meanwhile, the pyrimidine-2,4-diamine compound shows low toxicity and exhibits good application prospect.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 18, 2023
    Applicant: ANHUI MEDICAL UNIVERSITY
    Inventors: Xinhua LIU, Xing CHEN, Jingbo SHI, Mingming LIU, Yaoyao YAN, Zhaoyan ZHANG, Famin ZHANG
  • Patent number: 11629137
    Abstract: Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: April 18, 2023
    Assignee: Tesaro, Inc.
    Inventors: Alistair Stewart, Anthony Joseph Toto, Frank Xing Chen, George Wu
  • Publication number: 20230097145
    Abstract: The present disclosure is related to a multi-stage control negative Poisson self-expanding anchor apparatus. The apparatus is constructed to solve the problem of poor effect or even failure of anchor bolts owing to insufficient force area of the bolt and easy damage of the locking section under the action of large tension in the existing technology. The anchorage section mainly comprises a plurality of circular platform bodies spaced with larger outward and smaller inward along the axial direction. The axial inner segment of the round platform body is coaxial connected with the force resistant body, and the axial outer segment of the round platform body is opened with an axial inward through the hole of the force resistant body. The axial inner part of the force resistant body is fixed on the anchorage segment.
    Type: Application
    Filed: September 23, 2022
    Publication date: March 30, 2023
    Inventors: Xingsheng ZHANG, Jinyu DONG, Weihua LI, Mengke HU, Xinglong YANG, Xing CHEN, Yawen ZHAO
  • Publication number: 20230090373
    Abstract: Certain aspects of the present disclosure provide techniques for packet buffering. A method that may be performed by a receiving node includes dynamically determining one or more time durations to buffer packets. The one or more time durations can be different than a time duration of a configured timer for buffering the packets. The receiving node may input one or more parameters to a machine learning algorithm and obtain, as output of the machine learning algorithm based on the input one or more parameters, one or more time durations to buffer packets. The receiving node buffers packets for the determined one or more time durations. The receiving node may use machine learning to dynamically determine the one or more time durations to buffer packet. The buffering may be at a radio link control (RLC) reassembling buffer and/or a packet data convergence protocol (PDCP) buffer.
    Type: Application
    Filed: November 28, 2022
    Publication date: March 23, 2023
    Inventors: Vishal DALMIYA, Xing CHEN, Arun Prasanth BALASUBRAMANIAN, Vaishakh RAO, Leena ZACHARIAS, Vanitha Aravamudhan KUMAR, Shailesh MAHESHWARI, Kuo-Chun LEE
  • Publication number: 20220386303
    Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a wireless communication device may receive protocol data units (PDUs) in multiple TTIs (e.g., slots). The wireless communication device may generate, for each TTI of the multiple TTIs, a descriptor that identifies serial numbers (SNs) of PDUs that are received in the TTI. The wireless communication device may aggregate the descriptors for the multiple TTIs into an aggregated descriptor that identifies the SNs of the PDUs across the multiple TTIs. The wireless communication device may process the PDUs received in the multiple TTIs based at least in part on the aggregated descriptor. Numerous other aspects are described.
    Type: Application
    Filed: May 31, 2021
    Publication date: December 1, 2022
    Inventors: Akshay KUMAR, Arnaud MEYLAN, Xing CHEN, Shailesh MAHESHWARI, Lulu WANG, Ashwin RAMAN
  • Patent number: 11512387
    Abstract: Methods and apparatus for passivating a target are provided herein. For example, a method includes a) supplying an oxidizing gas into an inner volume of the process chamber; b) igniting the oxidizing gas to form a plasma and oxidize at least one of a target or target material deposited on a process kit disposed in the inner volume of the process chamber; and c) performing a cycle purge comprising: c1) providing air into the process chamber to react with the at least one of the target or target material deposited on the process kit; c2) maintaining a predetermined pressure for a predetermined time within the process chamber to generate a toxic by-product caused by the air reacting with the at least one of the target or target material deposited on the process kit; and c3) exhausting the process chamber to remove the toxic by-product.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: November 29, 2022
    Assignee: APPLIED MATERIALS, INC.
    Inventors: Chao Du, Xing Chen, Keith A. Miller, Jothilingam Ramalingam, Jianxin Lei
  • Patent number: 11507396
    Abstract: Techniques perform storage management. In accordance with such techniques, in response to determining that there is an abnormal process in a process group of an application, and a first size of storage space occupied by the abnormal process exceeds a first threshold, an abnormal process is terminated. A second size of storage space occupied by other processes than the abnormal process in the process group after the abnormal process is terminated is determined. In response to the second size exceeding a second threshold, at least one process in the process group to reduce the second size is terminated, where the at least one process is different from the abnormal process.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: November 22, 2022
    Assignee: EMC IP Holding Company LLC
    Inventors: Dazhi Dong, Binhua Lu, Shufang Meng, Xing Chen, Chen Zhang, Tongyin Xu
  • Patent number: 11474201
    Abstract: The present invention discloses a method of controlling transmitting frequencies of microwave source, which includes the following steps of: a) collecting reflection frequencies of a load according to a pre-set sampling rate; b) calculating a change rate of the reflection frequencies collected in the step a; c) setting a reflection frequency threshold and a change rate threshold; d) comparing the reflection frequencies and the change rate with the reflection frequency threshold and the change rate threshold respectively; wherein if the reflection frequencies or the change rate is less than the threshold goes to step e or returns to the step a; e) sending control signals to the microwave source and tuning the transmitting frequencies; and f) returning to step a. The present invention also discloses a microwave transmission system thereof. The present invention can be applied in controlling microwave source consists of single magnetron tube or multiple magnetron tubes.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: October 18, 2022
    Assignee: Sichuan University
    Inventors: Yang Yang, Kama Huang, Xing Chen, Changjun Liu, Huacheng Zhu
  • Publication number: 20220325934
    Abstract: The present application relates to the field of ice making, and provides an ice making system and a refrigeration apparatus. The ice making system includes an ice making assembly, a water collecting tank located below the ice making assembly, and a water diversion ice rake structure. The water diversion ice rake structure includes: a pair of water receiving lateral wings, each of which is constructed with a rotary end and a free end; the pair of water receiving lateral wings are rotatably disposed on opposite sides of the ice making assembly through the respective rotary ends to rotate between an ice making position and an ice falling position. At the ice making position, the free ends of the pair of water receiving lateral wings are butted in a space between the ice making assembly and the water collecting tank to form a closure space with an opening facing the ice making assembly, and a water outlet communicating with the water collecting tank is constructed on one side of the closure space.
    Type: Application
    Filed: December 30, 2019
    Publication date: October 13, 2022
    Inventors: Xing CHEN, Yang SHAO, Zanxi LIU, Jincai WANG, Zengqiang SI, Mingxing SUN, Cunyu LIU, Gang CUI
  • Publication number: 20220327724
    Abstract: A method for rapidly calculating intersection over union (IOU) between a target region and a designated region in an image is used in an electronic device. The electronic device detects a target object from an image received from a monitored location, and determines a designated region, a target region, and a combined region from the image, the target region including the target object. The electronic device calculates a first area of the designated region, a second area of the target region, and a third area of the combined region, and calculates a value of IOU according to formula of SIOU=(S1+S2?S3)/S2. S1 represents the first area, S2 represents the second area, and S3 represents the third area. The electronic device issues an intrusion warning in or concerning a monitored region according to a comparison result between the value of IOU and a preset threshold.
    Type: Application
    Filed: April 11, 2022
    Publication date: October 13, 2022
    Inventors: BIN-BIN LIANG, DONG-MING LI, JI-XING CHEN
  • Publication number: 20220310364
    Abstract: Methods and apparatus for cleaning a process kit configured for processing a substrate are provided. For example, a process chamber for processing a substrate can include a chamber wall; a sputtering target disposed in an upper section of the inner volume; a pedestal including a substrate support having a support surface to support a substrate below the sputtering target; a power source configured to energize sputtering gas for forming a plasma in the inner volume; a process kit surrounding the sputtering target and the substrate support; and an ACT connected to the pedestal and a controller configured to tune the pedestal using the ACT to maintain a predetermined potential difference between the plasma in the inner volume and the process kit, wherein the predetermined potential difference is based on a percentage of total capacitance of the ACT and a stray capacitance associated with a grounding path of the process chamber.
    Type: Application
    Filed: June 13, 2022
    Publication date: September 29, 2022
    Inventors: Halbert CHONG, Rong TAO, Jianxin LEI, Rongjun WANG, Keith A. Miller, Irena H. Wysok, Tza-Jing Gung, Xing Chen
  • Publication number: 20220310531
    Abstract: Exemplary methods of processing a semiconductor substrate may include forming a layer of dielectric material on the semiconductor substrate. The methods may include performing an edge exclusion removal of the layer of dielectric material. The methods may include forming a mask material on the semiconductor substrate. The mask material may contact the dielectric material at an edge region of the semiconductor substrate. The methods may include patterning an opening in the mask material overlying a first surface of the semiconductor substrate. The methods may include etching one or more trenches through the semiconductor substrate.
    Type: Application
    Filed: March 26, 2021
    Publication date: September 29, 2022
    Applicant: Applied Materials, Inc.
    Inventors: Amirhasan Nourbakhsh, Lan Yu, Joseph F. Salfelder, Ki Cheol Ahn, Tyler Sherwood, Siddarth Krishnan, Michael Jason Fronckowiak, Xing Chen
  • Publication number: 20220310363
    Abstract: Methods and apparatus for cleaning a process kit configured for processing a substrate are provided. For example, a process chamber for processing a substrate can include a chamber wall; a sputtering target disposed in an upper section of the inner volume; a pedestal including a substrate support having a support surface to support a substrate below the sputtering target; a power source configured to energize sputtering gas for forming a plasma in the inner volume; a process kit surrounding the sputtering target and the substrate support; and an ACT connected to the pedestal and a controller configured to tune the pedestal using the ACT to maintain a predetermined potential difference between the plasma in the inner volume and the process kit, wherein the predetermined potential difference is based on a percentage of total capacitance of the ACT and a stray capacitance associated with a grounding path of the process chamber.
    Type: Application
    Filed: June 13, 2022
    Publication date: September 29, 2022
    Inventors: Halbert CHONG, Rong TAO, Jianxin LEI, Rongjun WANG, Keith A. Miller, Irena H. Wysok, Tza-Jing Gung, Xing Chen
  • Publication number: 20220307126
    Abstract: Methods and apparatus for passivating a target are provided herein. For example, a method includes a) supplying an oxidizing gas into an inner volume of the process chamber; b) igniting the oxidizing gas to form a plasma and oxidize at least one of a target or target material deposited on a process kit disposed in the inner volume of the process chamber; and c) performing a cycle purge comprising: c1) providing air into the process chamber to react with the at least one of the target or target material deposited on the process kit; c2) maintaining a predetermined pressure for a predetermined time within the process chamber to generate a toxic by-product caused by the air reacting with the at least one of the target or target material deposited on the process kit; and c3) exhausting the process chamber to remove the toxic by-product.
    Type: Application
    Filed: June 13, 2022
    Publication date: September 29, 2022
    Inventors: Chao DU, Xing CHEN, Keith A. MILLER, Jothilingam RAMALINGAM, Jianxin LEI
  • Patent number: 11454114
    Abstract: Disclosed is a method for installing a groundwater monitoring well inside a permeable reactive barrier (PRB) trench including excavating a PRB trench, installing a trench side-wall support, positioning a monitoring well borehole, installing an outer installation casing for pre-burying the monitoring well, installing a monitoring well positioning bracket, installing a monitoring well casing, installing monitoring well filter packs and seal materials, filling the trench with PRB media and capping with a covering soil layer, removing the outer installation casing, removing the trench side-wall support, completing the monitoring well with a wellhead, and conducting well development.
    Type: Grant
    Filed: January 5, 2022
    Date of Patent: September 27, 2022
    Assignee: INSTITUTE OF SOIL SCIENCE, CHINESE ACADEMY OF SCIENCES
    Inventors: Xin Song, Peng Jin, Changlong Wei, Kang Li, Zhiwen Tang, Heng Fu, Xing Chen
  • Patent number: 11434235
    Abstract: Disclosed are a solid form of (E)-3-((R)-4-(((R)-6-(2-chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)acrylic acid, a preparation method therefor, a pharmaceutical composition comprising same, and the use thereof in the preparation of drugs for preventing or treating viral diseases.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: September 6, 2022
    Assignee: SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.
    Inventors: Tianming Wang, Chengxi Yang, Jiaqiang Cai, Wei Liu, Baolei Zhang, Qiang Tian, Shuai Song, Hao Hu, Weibiao Han, Youqiang Li, Xing Chen, Lichun Wang, Jingyi Wang
  • Publication number: 20220254886
    Abstract: Exemplary methods of forming a semiconductor structure may include forming a doped silicon layer on a semiconductor substrate. A level of doping may be increased at an increasing distance from the semiconductor substrate. The methods may include etching the doped silicon layer to define a trench extending to the semiconductor substrate. The doped silicon layer may define a sloping sidewall of the trench. The trench may be characterized by a depth of greater than or about 30 ?m. The methods may include lining the trench with a first oxide material. The methods may include depositing a second oxide material within the trench. The methods may include forming a contact to produce a power device.
    Type: Application
    Filed: February 8, 2021
    Publication date: August 11, 2022
    Applicant: Applied Materials, Inc.
    Inventors: Ashish Pal, El Mehdi Bazizi, Siddarth Krishnan, Xing Chen, Lan Yu, Tyler Sherwood
  • Patent number: 11405821
    Abstract: A method and apparatus for prioritizing data packets when stateful compression is enabled for wireless communications is disclosed. For example, the aspects include receiving a plurality of data packets scheduled in a first order for transmission. The described aspects further include prioritizing one or more data packets of the plurality of data packets as one or more prioritized data packets, each prioritized data packet being scheduled in an order for transmission different from the first order for transmission. The described aspects further include compressing one or more unprioritized data packets of the plurality of data packets into one or more compressed unprioritized data packets. The described aspects further include scheduling the one or more prioritized data packets and the one or more compressed unprioritized data packets in a second order for transmission, the second order differing from the first order.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: August 2, 2022
    Assignee: QUALCOMM Incorporated
    Inventors: Shailesh Maheshwari, Xing Chen, Vishal Dalmiya, Gang Xiao, Saket Bathwal, Peng Wu, Leena Zacharias
  • Patent number: 11382316
    Abstract: Provided herein non-human transgenic animals comprising a genome that: i) under-expresses, or is inducible to under-express, Hu Antigen R (HuR) in at least some neurons of said transgenic animal; ii) does not express HuR, or is inducible to not express HuR, in at least some neurons of said transgenic animal; or iii) does not express functional HuR, or is inducible to not express functional HuR in at least some neurons of said transgenic animal, as well as methods of screening drugs and therapies (e.g., useful in treating ALS) using such animals.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: July 12, 2022
    Assignee: The Cleveland Clinic Foundation
    Inventors: Xiaoxia Li, Tomasz Herjan, Kevin Sun, Xing Chen
  • Publication number: 20220214321
    Abstract: The present application is directed to a method of measuring the concentration of radicals in a gas stream which includes the steps of flowing a radical gas stream emitted from at least one radical gas generator to at least one processing chamber, providing at least one sampling reaction module having at least one sampling tube therein, establishing a reference temperature of the sampling tube with at least one thermal control module, diverting a portion of the radical gas steam from the radical gas generator into the sampling tube, reacting at least one reagent with at least one radical gas within a defined volume of the radical gas stream thereby forming at least one chemical species within at least one compound stream, the compound stream flowing within the sampling tube, measuring a change of temperature of the sampling tube due to interaction of the chemical species within the compound stream and the sampling tube with sensor module, and calculating a concentration of the chemical species within the comp
    Type: Application
    Filed: January 25, 2022
    Publication date: July 7, 2022
    Applicant: MKS Instruments, Inc.
    Inventors: Johannes Chiu, Xing Chen, Chiu-Ying Tai, Michael Harris, Atul Aupta