Patents by Inventor Xing Liao

Xing Liao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220358059
    Abstract: An improved data access method for direct memory access (DMA), comprising: allocating m DMA hardware descriptors, and n data buffer units from a data buffer to the controller; constructing software descriptors of the buffer into a two-dimensional array with each row directing to one buffer unit, wherein the value of a first subscript of each array item ranges between 0 and n?1, and the value of a second subscript ranges between 0 and 1; respectively storing a virtual and physical address of the same buffer unit in a column of the two-dimensional array of the corresponding software descriptor; creating an index to establish a directional relationship between the buffer units and the software descriptors, the index comprising an idle index and a scheduling index; and implementing the hardware and software descriptors access by the CPU and DMA to a memory in a data transfer process of the high-speed interface.
    Type: Application
    Filed: April 25, 2022
    Publication date: November 10, 2022
    Inventor: Xing Liao
  • Publication number: 20200347393
    Abstract: The present invention generally relates to micro- and nanoneedles, e.g., for use in penetrating plant cells, or other cells. In some embodiments, delivery of target biomolecules into cells with protective outer layers (e.g. plant cells or plant pollen), cells in seeds, or cells in tissues may be achieved. These outer layers could be native biological protections (e.g. complex exines for pollens), other types of cells, or general biological materials. In some cases, the needles are attached at an end on a surface. In some cases, pollen or seeds may have substantially thick and tough layers (intine and exine), which may render it more difficult to penetrate such materials, as compared with cell membranes, e.g., in mammalian cells.
    Type: Application
    Filed: December 7, 2018
    Publication date: November 5, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Hongkun Park, Xing Liao, Jeffrey T. Abott, Steven Ban, Tianyang Ye
  • Publication number: 20180059550
    Abstract: In accordance with an embodiment of the disclosure, a tip array can include an elastomeric tip substrate layer comprising a first surface and an oppositely disposed second surface, the tip substrate layer being formed from an elastomeric material; a plurality of tips fixed to the first surface, the tips each comprising a tip end disposed opposite the first surface, the tips having a radius of curvature of less than about 1 micron; and an array of heaters disposed on the second surface of the tip substrate layer and configured such that when the tip substrate layer is heated by a heater, a tip disposed in a location of a heated portion of tip substrate layer is lowered relative to a tip disposed in a location of an unheated portion of the tip substrate layer.
    Type: Application
    Filed: September 1, 2017
    Publication date: March 1, 2018
    Inventors: Chad A. Mirkin, Xing Liao, Keith A. Brown, Guoliang Liu, Abrin L. Schmucke, Shu He, Wooyoung Shim, Daniel J. Eichelsdoerfer, Boris Rasin
  • Patent number: 9766551
    Abstract: In accordance with an embodiment of the disclosure, a method of patterning can include dividing an image into a set of frame sections; determining a tip pattern for a respective portion of an image to be patterned by each tip of the tip array in each frame section of the set of frame sections; disposing the tip array in a patterning position in a first location of the substrate corresponding to a location of the substrate in which the first frame section in the set of frame sections is to be patterned; projecting a first pattern of radiation onto the tip array to selectively irradiate one or more tips of the tip array and pattern the substrate, wherein the first pattern of radiation corresponds to a tip pattern for the first frame section; disposing the tip array in a patterning position in a second location of the substrate corresponding to a location of the substrate in which the second frame section in the set of frame sections is to be patterned; projecting a second pattern of radiation onto the tip array
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: September 19, 2017
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Xing Liao, Keith A. Brown, Guoliang Liu, Abrin L. Schmucker, Shu He, Wooyoung Shim, Daniel J. Eichelsdoerfer, Boris Rasin
  • Publication number: 20150309073
    Abstract: A coat micro tip can include a tip having a base and an oppositely disposed tip end having a radius of curvature of less than 1 ?m and a graphene film conformally coated on the tip.
    Type: Application
    Filed: July 12, 2013
    Publication date: October 29, 2015
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Wooyoung Shim, Keith A. Brown, Boris Rasin, Xing Liao, Xiaozhu Zhou
  • Publication number: 20150286148
    Abstract: In accordance with an embodiment of the disclosure, a method of patterning can include dividing an image into a set of frame sections; determining a tip pattern for a respective portion of an image to be patterned by each tip of the tip array in each frame section of the set of frame sections; disposing the tip array in a patterning position in a first location of the substrate corresponding to a location of the substrate in which the first frame section in the set of frame sections is to be patterned; projecting a first pattern of radiation onto the tip array to selectively irradiate one or more tips of the tip array and pattern the substrate, wherein the first pattern of radiation corresponds to a tip pattern for the first frame section; disposing the tip array in a patterning position in a second location of the substrate corresponding to a location of the substrate in which the second frame section in the set of frame sections is to be patterned; projecting a second pattern of radiation onto the tip array
    Type: Application
    Filed: October 15, 2013
    Publication date: October 8, 2015
    Inventors: Chad A. Mirkin, Xing Liao, Keith A. Brown, Guoliang Liu, Abrin L. Schmucker, Shu He, Wooyoung Shim, Daniel J. Eichelsdoerfer, Boris Rasin
  • Patent number: 8961853
    Abstract: Disclosed are methods of lithography using a tip array having a plurality of pens attached to a backing layer, where the tips can comprise a metal, metalloid, and/or semi-conducting material, and the backing layer can comprise an elastomeric polymer. The tip array can be used to perform a lithography process in which the tips are coated with an ink (e.g., a patterning composition) that is deposited onto a substrate upon contact of the tip with the substrate surface. The tips can be easily leveled onto a substrate and the leveling can be monitored optically by a change in light reflection of the backing layer and/or near the vicinity of the tips upon contact of the tip to the substrate surface.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: February 24, 2015
    Assignee: Northwestern University
    Inventors: Chad A. Mirkin, Wooyoung Shim, Adam B. Braunschweig, Xing Liao, Jinan Chai, Jong Kuk Lim, Gengfeng Zheng, Zijian Zheng
  • Patent number: 8753813
    Abstract: The disclosure relates to a method of forming a pattern having pattern elements with a plurality of sizes on a substrate surface with a tilted pen array that includes choosing a tilt geometry for a pen array with respect to a substrate, inducing the tilt geometry between the pen array and the substrate surface, and forming a pattern having pattern elements on the substrate surface with the titled pen array, whereby the size of the formed pattern elements varies across the substrate surface along the tilted axis or axes. For example, the tilt geometry is in reference to the substrate surface and comprises a first angle with respect to a first axis of the substrate and a second angle with respect to a second axis of the substrate, the second axis being perpendicular to the first axis, and at least one of the first and second angles being non-zero.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: June 17, 2014
    Assignee: Northwestern University
    Inventors: Chad A. Mirkin, Adam B. Braunschweig, Jinan Chai, Dan J. Eichelsdoerfer, Louise R. Giam, Xing Liao, Lu Shin Wong
  • Patent number: 8745761
    Abstract: A method of leveling a polymer pen array includes contacting a pen array with a surface and measuring a total force exerted on the surface by the pen array, the pen array being disposed at a first angle with respect to a first axis of the surface and a second angle with respect to a second axis of the surface; tilting one or both of the pen array and the surface to vary the first and second angles of the pen array with respect to the surface; measuring the total force exerted by the tilted pen array on the surface; and repeating the tilting and measuring steps until a global maximum of the total force exerted on the surface by the pen array is measured, thereby determining first and second angles which correspond to a leveled position of the pen array with respect to the surface.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: June 3, 2014
    Assignee: Northwestern University
    Inventors: Chad A. Mirkin, Xing Liao, Adam B. Braunschweig
  • Publication number: 20130040856
    Abstract: The disclosure relates to a method of forming a pattern having pattern elements with a plurality of sizes on a substrate surface with a tilted pen array that includes choosing a tilt geometry for a pen array with respect to a substrate, inducing the tilt geometry between the pen array and the substrate surface, and forming a pattern having pattern elements on the substrate surface with the titled pen array, whereby the size of the formed pattern elements varies across the substrate surface along the tilted axis or axes. For example, the tilt geometry is in reference to the substrate surface and comprises a first angle with respect to a first axis of the substrate and a second angle with respect to a second axis of the substrate, the second axis being perpendicular to the first axis, and at least one of the first and second angles being non-zero.
    Type: Application
    Filed: December 2, 2010
    Publication date: February 14, 2013
    Applicant: NORTHEWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Adam B. Braunschweig, Jinan Chai, Dan J. Eichelsdoerfer, Louise R. Giam, Xing Liao, Lu Shin Wong
  • Publication number: 20120167262
    Abstract: Disclosed are methods of lithography using a tip array having a plurality of pens attached to a backing layer, where the tips can comprise a metal, metalloid, and/or semi-conducting material, and the backing layer can comprise an elastomeric polymer. The tip array can be used to perform a lithography process in which the tips are coated with an ink (e.g., a patterning composition) that is deposited onto a substrate upon contact of the tip with the substrate surface. The tips can be easily leveled onto a substrate and the leveling can be monitored optically by a change in light reflection of the backing layer and/or near the vicinity of the tips upon contact of the tip to the substrate surface.
    Type: Application
    Filed: June 4, 2010
    Publication date: June 28, 2012
    Applicant: Northwestern University
    Inventors: Chad A. Mirkin, Wooyoung Shim, Adam B. Braunschweig, Xing Liao, Jinan Chai, Jong Kuk Lim, Gengfeng Zheng, Zijian Zheng
  • Publication number: 20110165329
    Abstract: A method of leveling a polymer pen array includes contacting a pen array with a surface and measuring a total force exerted on the surface by the pen array, the pen array being disposed at a first angle with respect to a first axis of the surface and a second angle with respect to a second axis of the surface; tilting one or both of the pen array and the surface to vary the first and second angles of the pen array with respect to the surface; measuring the total force exerted by the tilted pen array on the surface; and repeating the tilting and measuring steps until a global maximum of the total force exerted on the surface by the pen array is measured, thereby determining first and second angles which correspond to a leveled position of the pen array with respect to the surface.
    Type: Application
    Filed: December 3, 2010
    Publication date: July 7, 2011
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Xing Liao, Adam B. Braunschweig
  • Publication number: 20100115672
    Abstract: A dual tip probe for scanning probe epitaxy and a method of forming the dual tip probe are disclosed. The dual tip probe includes first and second tips disposed on a cantilever arm. The first and second tips can be a reader tip and a synthesis tip, respectively. The first tip can remain in contact with a substrate during writing and provide in situ characterization of the substrate and or structures written, while the second tip can perform in non-contact mode to write and synthesis nanostructures. This feature can allow the dual tip probe to detect errors in a printed pattern using the first tip and correct the errors using the second tip.
    Type: Application
    Filed: May 13, 2009
    Publication date: May 6, 2010
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Chang Liu, Yuhuang Wang, Adam B. Braunschweig, Xing Liao, Louise R. Giam, Byung Y. Lee, Shifeng Li
  • Publication number: 20100071098
    Abstract: A dual tip probe for scanning probe epitaxy is disclosed. The dual tip probe includes first and second tips disposed on a cantilever arm. The first and second tips can be a reader tip and a synthesis tip, respectively. The dual tip probe further includes a rib disposed on the cantilever arm between the first and second tips. The dual tip probe can also include a strain gauge disposed along the length of the cantilever arm.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 18, 2010
    Applicants: NORTHWESTERN UNIVERSITY, Nanolnk, Inc.
    Inventors: Chad A. Mirkin, Chang Liu, Yuhuang Wang, Adam B. Braunschweig, Xing Liao, Louise R. Giam, Byung Y. Lee, Shifeng Li, Joseph S. Fragala, Albert K. Henning
  • Patent number: D835604
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: December 11, 2018
    Inventor: Xing Liao
  • Patent number: D879283
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: March 24, 2020
    Inventor: Xing Liao