Patents by Inventor Xinhua Liu

Xinhua Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230296021
    Abstract: A three-level prevention and control method for a rock burst roadway, the method comprising: pre-weakening a thick and hard rock layer above a roadway before the roadway is excavated; carrying out prestress support, pressure relief and reinforcement when the roadway is excavated; and carrying out stress transfer on an advance abutment pressure, and arranging a composite energy absorption protective structure around the roadway before the mining of a working face. By coordinating the spatio-temporal relationship between pressure relief, support and prevention, the energy dissipation in the rock burst roadway is changed from an unstable, disorderly and uncontrollable dissipation state to a stable, orderly and controllable dissipation state.
    Type: Application
    Filed: April 15, 2021
    Publication date: September 21, 2023
    Applicant: CCTEG COAL MINING RESEARCH INSTITUTE
    Inventors: Yongzheng Wu, Yukai Fu, Xiaowei Chu, Jinyu Chen, Jie He, Xinhua Liu, Xianzhi Meng
  • Patent number: 11674570
    Abstract: A self-adaptive heavy-duty gear transmission walking device includes a guide track. A carrying seat is slidably installed on the guide track. A loading platform is arranged on the carrying seat, and matching frames are arranged at the bottom of the carrying seat and positioned opposite from each other. A first driving mechanism, a walking mechanism, a first support bracket, a stop mechanism, and a second support bracket are arranged on the carrying seat. A vertical support mechanism and a horizontal support mechanism are arranged in the matching frame. The first driving mechanism is connected to one end of the walking mechanism. The walking mechanism penetrates through the carrying seat and is magnetically connected to the guide track. The other end of the walking mechanism is connected to a first transmission shaft. The first transmission shaft penetrates through the first support bracket and is fixedly installed with a brake disc.
    Type: Grant
    Filed: October 11, 2022
    Date of Patent: June 13, 2023
    Assignees: XUZHOU XCMG DRIVELINE TECHNOLOGY CO., LTD., XUZHOU UNIVERSITY OF TECHNOLOGY
    Inventors: Datong Qin, Nong Zhang, Liqiao Jiang, Ming Ma, Chang Lyu, Zhongbin Wang, Jianjun Hu, Chuanhui Huang, Dandan Sun, Jun Song, Haodong Yin, Lige Xue, Minghu He, Hongrui Zhu, Minghui Hu, Yonggang Liu, Changzhao Liu, Xinhua Liu, Kun Han, Shengcheng Wang
  • Publication number: 20230150947
    Abstract: A pyrimidine-2,4-diamine compound and a preparation method and application thereof are provided. The pyrimidine-2,4-diamine compound of the present disclosure can be used in the research of biological or pharmacological phenomena and cathepsin C-involved signal pathway transduction and the evaluation of novel cathepsin C inhibitors. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-cathepsin C activity in vitro and in vivo and proved to have strong inhibitory activity on cathepsin C. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-NSP activity in vivo and proved to have strong inhibitory activity on NSP. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-inflammatory activity in vivo and proved to have an effective therapeutic effect on inflammatory disease models. Meanwhile, the pyrimidine-2,4-diamine compound shows low toxicity and exhibits good application prospect.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 18, 2023
    Applicant: ANHUI MEDICAL UNIVERSITY
    Inventors: Xinhua LIU, Xing CHEN, Jingbo SHI, Mingming LIU, Yaoyao YAN, Zhaoyan ZHANG, Famin ZHANG
  • Patent number: 11647879
    Abstract: A multifunctional emergency starting power for motor vehicles is provided, including a bracket (10), an accumulator (20) mounted on the bracket (10), a first interface (50) for charging the accumulator (20), and a second interface (30) for outputting an emergency starting voltage to a motor vehicle. The bracket (10) is also installed with a vacuum cleaner (70) and a controller (60) for controlling the operation of the vacuum cleaner and the charging of the accumulator. The accumulator is respectively connected to the vacuum cleaner and the controller and supplies an electrical energy thereto. The emergency starting power and the vacuuming function are integrated, and the battery of the emergency starting power is configured for powering the vacuum cleaner and the controller of the emergency starting power is configured for controlling the power charging and the vacuum cleaner work.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: May 16, 2023
    Assignee: SHENZHEN CHIC ELECTRICS CO. LTD.
    Inventor: Xinhua Liu
  • Patent number: 11552536
    Abstract: An electric motor and inverter assembly (100) used in an electric vehicle or a hybrid electric vehicle to drive the vehicle's wheels to rotate is disclosed. The electric motor and inverter assembly comprises: an electric motor (300), which includes a housing including a main shell (310), an end cover (320) and a connecting cover (330), wherein a cooling passage is formed in a wall of the housing such that coolant is able to flow in the cooling passage, and an end cover (320) and a connecting cover (330) are respectively connected to opposite ends of the main shell; and an inverter, which includes a housing (210) in which a power element and/or an electrical device is received, wherein the housing of the inverter contacts the connecting cover such that an interface is defined between the connecting cover and the housing of the inverter, and the coolant flowing through the cooling passage is able to contact the interface.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: January 10, 2023
    Assignee: Robert Bosch GmbH
    Inventors: Tao Zhu, Yanlin Li, Xinhua Liu, Takashi Shigematsu, Heinz-Bernd Haiser, Peter Ropertz, Ralf Schmid, Shi Deng
  • Patent number: 11511018
    Abstract: A method for preparing a conductive biomimetic skin scaffold material with self-repairing function includes the following steps: adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to a homogeneous dispersion of acidified carbon nanotubes, poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and gelatin to cross-link to obtain a conductive composite colloid; and injecting the conductive composite colloid into a mold, aging at ?4-4° C. for 12-24 hours, and then soaking in a phosphate-buffered saline (PBS) solution with a pH of 7.0-7.4 for 12-24 hours to obtain the conductive biomimetic skin scaffold material.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: November 29, 2022
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xuechuan Wang, Manhui Zheng, Xinhua Liu, Ouyang Yue, Mengdi Hou, Youyou Wang
  • Patent number: 11446270
    Abstract: This invention belongs to the modern pharmaceutical field of Traditional Chinese Medicine, and relates to an herbal extract of Chinese Motherwort and its application in pharmacy, which specifically relates to the crystal structure of a Chinese Motherwort extract: Leonurine, and its application in the preparation of medicine. The chemical name of the above-mentioned Leonurine is 4-guanidino-1-)butyl 4-hydroxy-3,5-dimethoxybenzoate. The invention by specific methods prepares leonurine as 6 kinds of crystals with different crystal forms. Specifically, there are six different structures of leonurine sulfate crystals, two of them are hydrate, two are anhydrous crystal form, one is methanol solvate, one is ethanol solvate. The leonurine crystal forms of this invention can applicate in preparing medicine such as insulin sensitizer, hypoglycemic and lipid-lowering drugs.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: September 20, 2022
    Assignee: ZHUHAI HENGQIN NEW DISTRICT ZHONGZHU ZHENGTAI MEDICAL MANAGEMENT CO., LTD.
    Inventors: Yichun Zhu, Yizhun Zhu, Xinhua Liu, Ying Chen, Rinkiko Suguro, Yanfei Zhang
  • Publication number: 20220110494
    Abstract: A multifunctional emergency starting power for motor vehicles is provided, including a bracket (10), an accumulator (20) mounted on the bracket (10), a first interface (50) for charging the accumulator (20), and a second interface (30) for outputting an emergency starting voltage to a motor vehicle. The bracket (10) is also installed with a vacuum cleaner (70) and a controller (60) for controlling the operation of the vacuum cleaner and the charging of the accumulator. The accumulator is respectively connected to the vacuum cleaner and the controller and supplies an electrical energy thereto. The emergency starting power and the vacuuming function are integrated, and the battery of the emergency starting power is configured for powering the vacuum cleaner and the controller of the emergency starting power is configured for controlling the power charging and the vacuum cleaner work.
    Type: Application
    Filed: April 23, 2020
    Publication date: April 14, 2022
    Inventor: XINHUA LIU
  • Publication number: 20220023507
    Abstract: A method for preparing a conductive biomimetic skin scaffold material with self-repairing function includes the following steps: adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to a homogeneous dispersion of acidified carbon nanotubes, poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and gelatin to cross-link to obtain a conductive composite colloid; and injecting the conductive composite colloid into a mold, aging at ?4-4° C. for 12-24 hours, and then soaking in a phosphate-buffered saline (PBS) solution with a pH of 7.0-7.4 for 12-24 hours to obtain the conductive biomimetic skin scaffold material.
    Type: Application
    Filed: March 16, 2021
    Publication date: January 27, 2022
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xuechuan WANG, Manhui ZHENG, Xinhua LIU, Ouyang YUE, Mengdi HOU, Youyou WANG
  • Publication number: 20210070723
    Abstract: Provided are a crystal form of a sesquiterpene derivative, a preparation method therefor and the use thereof. In an X-ray powder diffraction pattern of crystal form A, there are characteristic diffraction peaks at positions corresponding to the 2? diffraction angles of 6.840±0.2, 9.390±0.2, 15.980±0.2, 16.830±0.2, 17.780±0.2, 18.760±0.2, 19.340±0.2, 20.400±0.2, 21.910±0.2, 23.280±0.2, 25.520±0.2, 26.680±0.2, 27.490±0.2, 32.110±0.2, 32.300±0.2, 37.980±0.2 and 44.230±0.2. The crystal form A has a high degree of crystallinity and is basically non-hygroscopic; in addition, same shows more favorable dissolution kinetics and has a bioavailability that can reach 85.8%.
    Type: Application
    Filed: November 22, 2018
    Publication date: March 11, 2021
    Applicants: Nankai University, Uni-Hua (Tianjin) Scientific Industries Pty. Ltd.
    Inventors: Cheng YANG, Guang YANG, Honggang ZHOU, Tao SUN, Shuangwei LIU, Xinhua LIU, Tongtong LIU
  • Patent number: 10919952
    Abstract: A method for preparing a collagen from a chromium-containing tanned leather waste is disclosed. The method includes acid dechromation, obtaining a collagen aggregate, and converting the collagen aggregate to the collagen. The method also includes a reaction in a supercritical carbon dioxide reactor.
    Type: Grant
    Filed: March 2, 2019
    Date of Patent: February 16, 2021
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xuechuan Wang, Mengdi Hou, Xinhua Liu, Chengyuan Liang, Ouyang Yue, Manhui Zheng, Xing Zhu, Qingxin Han, Ji Li, Huijie Zhang, Taotao Qiang
  • Patent number: 10830044
    Abstract: A system and method for remotely locating a communication error support for hydraulic supports. The system includes a control panel, a support controller, a data converter, and two support drivers of the same type. Each support driver has two bus interfaces. The control panel transmits a control command to the data converter in a form of a WiFi signal. The data converter converts the WiFi signal into a message signal and transmits the message signal to the support controller. The support controller transmits the control command to the two support drivers, respectively. The support drivers transmit the command through CANH twisted pairs and CANL twisted pairs. When a bus for transmitting the command of a certain node has an error, the support controller calculates the fault node according to a formula n = p ? t 8 ? m , and feeds back the fault node onto the control panel.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: November 10, 2020
    Assignees: CHINA UNIVERSITY OF MINING AND TECHNOLOGY, XUZHOU GOLDFLUID HYDRAULIC TECHNOLOGY DEVELOPMENT CO., LTD.
    Inventors: Chao Tan, Zhongbin Wang, Hongya Zhou, Lei Si, Xinhua Liu, Xuliang Lu, Xiaoyu Li, Bowen Liu, Yue Wu, Honglin Wu
  • Patent number: 10815348
    Abstract: A method of preparing an aesculin sturgeon skin gelatin with antioxidant activity and Enterococcus faecalis detection ability includes: 1) mixing a sturgeon skin gelatin and distilled water in a ratio of 1:15-1:25 (w/v) at 50-70° C. and filtering to obtain a sturgeon skin gelatin solution; 2) adding aesculin and a glycerin solution to the sturgeon skin gelatin solution, stirring the resulted sturgeon skin gelatin solution at 30-50° C. for 30 minutes, and filtering; and 3) removing air bubbles from the sturgeon skin gelatin solution of step 2) under reduced pressure, placing the sturgeon skin gelatin solution on an acrylic glass, and drying the sturgeon skin gelatin solution at in a vented oven 25° C. and 45-55% relative humidity for 24 hours to obtain the aesculin sturgeon skin gelatin film.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: October 27, 2020
    Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xuechuan Wang, Ouyang Yue, Xinhua Liu, Taotao Qiang, Longfang Ren, Lei Tian, Minyi Jia, Xingke Ju, Chengyuan Liang
  • Publication number: 20200280238
    Abstract: An electric motor and inverter assembly (100) used in an electric vehicle or a hybrid electric vehicle to drive the vehicle's wheels to rotate is disclosed. The electric motor and inverter assembly comprises: an electric motor (300), which includes a housing including a main shell (310), an end cover (320) and a connecting cover (330), wherein a cooling passage is formed in a wall of the housing such that coolant is able to flow in the cooling passage, and an end cover (320) and a connecting cover (330) are respectively connected to opposite ends of the main shell; and an inverter, which includes a housing (210) in which a power element and/or an electrical device is received, wherein the housing of the inverter contacts the connecting cover such that an interface is defined between the connecting cover and the housing of the inverter, and the coolant flowing through the cooling passage is able to contact the interface.
    Type: Application
    Filed: September 18, 2017
    Publication date: September 3, 2020
    Inventors: Tao Zhu, Yanlin Li, Xinhua Liu, Takashi Shigematsu, Heinz-Bernd Haiser, Peter Ropertz, Ralf Schmid, Shi Deng
  • Patent number: 10701928
    Abstract: A method for disinfecting and sterilizing an animal tissue material and a corresponding soak solution for an animal tissue. The method includes placing the animal tissue material into an alkaline soak solution containing a metal peroxide and a detergent, and shaking; removing organic components released from microorganisms and animal tissue cells by soaking and washing in a neutral cleaning solution; washing the tissue matrix with a weak acidic cleaning solution; cryopreserving or freeze-drying the tissue matrix in a neutral solution. The soak solution for the animal tissue contains 0.01˜0.2% (w/v) of the metal peroxide and 0.05˜1.0% (w/v) of the detergent. The animal tissue pretreated by the method is advantageous to the preservation and further decellularization treatment of the tissue for manufacture of an intact scaffold material of a tissue matrix.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: July 7, 2020
    Assignee: Beijing Ruijian Gaoke Biotechnology Co., Ltd.
    Inventors: Zhi-gang Liu, Xinhua Liu
  • Publication number: 20200069633
    Abstract: This invention belongs to the modern pharmaceutical field of Traditional Chinese Medicine, and relates to an herbal extract of Chinese Motherwort and its application in pharmacy, which specifically relates to the crystal structure of a Chinese Motherwort extract: Leonurine, and its application in the preparation of medicine. The chemical name of the above-mentioned Leonurine is 4-guanidino-1-)butyl 4-hydroxy-3,5-dimethoxybenzoate. The invention by specific methods prepares leonurine as 6 kinds of crystals with different crystal forms. Specifically, there are six different structures of leonurine sulfate crystals, two of them are hydrate, two are anhydrous crystal form, one is methanol solvate, one is ethanol solvate. The leonurine crystal forms of this invention can applicate in preparing medicine such as insulin sensitizer, hypoglycemic and lipid-lowering drugs.
    Type: Application
    Filed: September 18, 2018
    Publication date: March 5, 2020
    Inventors: Yichun ZHU, Yizhun ZHU, Xinhua LIU, Ying CHEN, Rinkiko SUGURO, Yanfei ZHANG
  • Publication number: 20190309051
    Abstract: A method for preparing a collagen from a chromium-containing tanned leather waste is disclosed. The method includes acid dechromation, obtaining a collagen aggregate, and converting the collagen aggregate to the collagen. The method also includes a reaction in a supercritical carbon dioxide reactor.
    Type: Application
    Filed: March 2, 2019
    Publication date: October 10, 2019
    Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xuechuan WANG, Mengdi HOU, Xinhua LIU, Chengyuan LIANG, Ouyang YUE, Manhui ZHENG, Xing ZHU, Qingxin HAN, Ji LI, Huijie ZHANG, Taotao QIANG
  • Patent number: 10426868
    Abstract: A method for manufacturing an animal acellular tissue matrix material and a tissue matrix material manufactured by the same. The tissue matrix material manufactured by the method retains an original basic scaffold structure of a tissue extracellular matrix, with an antigen causing immunological rejection in a human body being effectively removed from the animal tissue. An animal dermal matrix manufactured by the method retains the biological integrity of a natural dermal tissue matrix and can be used for restoration and repair of lesion and missing tissues.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: October 1, 2019
    Assignee: Beijing Ruijian Gaoke Biotechnology Co., Ltd.
    Inventors: Zhi-gang Liu, Xinhua Liu
  • Patent number: 9901440
    Abstract: The present invention relates to a support device for breast prosthesis based on an acellular matrix material of a biological tissue. The support device for breast prosthesis is formed by tailoring a membranaceous material into a petal-shaped planar biological matrix blank and by connecting adjacent edges thereof. The support device can match with the breast prosthesis; and provide a support, fixation and coverage for the breast prosthesis in various surgical operations such as mammoplasty and breast orthopedics, to avoid the ptosis and translocation of the breast prosthesis, thereby achieving desirable effects of plastic surgery. Once being implanted, the matrix material of a biological tissue can be integrated into the surrounding breast tissue of the subject, and thus transformed into new tissues in human body without the retention of foreign bodies. The present invention further relates to a method for manufacturing a support device, and a membranaceous biological matrix material.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: February 27, 2018
    Assignee: Beijing Ruijian Gaoke Biotechnology Co., Ltd.
    Inventors: Zhi-gang Liu, Xinhua Liu
  • Patent number: D851586
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: June 18, 2019
    Assignee: Shenzhen Chic Electrics Co. Ltd.
    Inventor: Xinhua Liu